Functional motor recovery is improved due to local placement of GDNF microspheres after delayed nerve repair

Biotechnology and Bioengineering

Volumn 110, Issue 5, 2013, Pages 1272-1281

  Wood, Matthew D ^a,b   Gordon, Tessa ^a,b   Kemp, Stephen W P ^a,b   Liu, Edward H ^a,b   Kim, Howard ^c   Shoichet, Molly S ^c   Borschel, Gregory H ^a,b,c,d  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b HOSPITAL FOR SICK CHILDREN RESEARCH INSTITUTE   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

^d UNIVERSITY OF TORONTO   (Canada)

Author keywords

Chronic axotomy; Chronic denervation; Common fibular nerve; Drug delivery; Regenerative medicine

Indexed keywords

AXOTOMY; COMMON FIBULAR; DELETERIOUS EFFECTS; DENERVATION; EXPERIMENTAL GROUPS; FUNCTIONAL RECOVERY; PERIPHERAL NERVE REGENERATION; REGENERATIVE MEDICINE;

DRUG DELIVERY; MICROSPHERES; MUSCLE;

REPAIR;

FIBRIN GLUE; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; MICROSPHERE; POLYGLACTIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL COUNT; CONTROLLED STUDY; DISEASE MODEL; DRUG DELIVERY SYSTEM; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GEL; HEART MUSCLE CONTRACTILE FORCE; HISTOLOGY; MOTOR PERFORMANCE; MUSCLE MASS; NERVE FIBER; NERVE INJURY; NERVE REGENERATION; NONHUMAN; RAT;

ANALYSIS OF VARIANCE; ANIMALS; AXONS; DRUG CARRIERS; FEMALE; FIBRIN TISSUE ADHESIVE; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR; LACTIC ACID; MICROSPHERES; MUSCLE FIBERS, SKELETAL; MUSCULAR ATROPHY; MYELIN SHEATH; POLYGLYCOLIC ACID; RATS; RATS, SPRAGUE-DAWLEY; SCIATIC NERVE;

RATTUS;

EID: 84875528057     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.24800     Document Type: Article

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