Epidermal growth factor inhibits transforming growth factor-β-induced fibrogenic differentiation marker expression through ERK activation

Cellular Signalling

Volumn 26, Issue 10, 2014, Pages 2276-2283

  Liu, Xiaoying ^a   Hubchak, Susan C ^a   Browne, James A ^a   Schnaper, H William ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

EGF; EMT; ERK; Fibrosis; Smad2 3; TGF

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; COLLAGEN TYPE 1; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE INHIBITOR; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; PHOSPHATIDYLINOSITOL 3 KINASE; SMAD2 PROTEIN; SMAD3 PROTEIN; STRESS ACTIVATED PROTEIN KINASE; TRANSFORMING GROWTH FACTOR BETA; ACTA2 PROTEIN, HUMAN; ACTIN; COLLAGEN TYPE I, ALPHA 1 CHAIN; EPIDERMAL GROWTH FACTOR RECEPTOR; HOMEODOMAIN PROTEIN; MAP2K1 PROTEIN, HUMAN; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; REPRESSOR PROTEIN; SMAD2 PROTEIN, HUMAN; TGIF1 PROTEIN, HUMAN; TRANSFORMING GROWTH FACTOR BETA1;

ARTICLE; CELL STIMULATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; EPITHELIAL MESENCHYMAL TRANSITION; EPITHELIUM CELL; GENE EXPRESSION; HUMAN; HUMAN CELL; KIDNEY FIBROSIS; KIDNEY PROXIMAL TUBULE; KIDNEY TUBULE EPITHELIUM; NUCLEOCYTOPLASMIC TRANSPORT; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; ANTAGONISTS AND INHIBITORS; CELL LINE; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PHOSPHORYLATION;

ACTINS; CELL LINE; COLLAGEN TYPE I; ENZYME ACTIVATION; EPIDERMAL GROWTH FACTOR; EPITHELIAL-MESENCHYMAL TRANSITION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE EXPRESSION REGULATION; HOMEODOMAIN PROTEINS; HUMANS; MAP KINASE KINASE 1; PHOSPHORYLATION; PROMOTER REGIONS, GENETIC; RECEPTOR, EPIDERMAL GROWTH FACTOR; REPRESSOR PROTEINS; SMAD2 PROTEIN; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84904906776     PISSN: 08986568     EISSN: 18733913     Source Type: Journal    
DOI: 10.1016/j.cellsig.2014.05.018     Document Type: Article

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