메뉴 건너뛰기




Volumn 229, Issue 11, 2014, Pages 1595-1606

PPARγ and RXR Ligands Disrupt the Inflammatory Cross-talk in the Hypoxic Breast Cancer Stem Cells Niche

Author keywords

[No Author keywords available]

Indexed keywords

6 OH 11 O HYDROXYPHENANTHRENE; APOLIPOPROTEIN E; CARBONATE DEHYDRATASE IX; GELATINASE A; GELATINASE B; HYPOXIA INDUCIBLE FACTOR 1ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; JAGGED1; NOTCH3 RECEPTOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PHENANTHRENE DERIVATIVE; PIOGLITAZONE; RETINOID X RECEPTOR; UNCLASSIFIED DRUG;

EID: 84904876378     PISSN: 00219541     EISSN: 10974652     Source Type: Journal    
DOI: 10.1002/jcp.24601     Document Type: Article
Times cited : (50)

References (56)
  • 3
    • 83555177230 scopus 로고    scopus 로고
    • Inflamm-aging of the stem cell niche: Breast cancer as a paradigmatic example: Breakdown of the multi-shell cytokine network fuels cancer in aged people
    • Bonafè M, Storci G, Franceschi C. 2012. Inflamm-aging of the stem cell niche: Breast cancer as a paradigmatic example: Breakdown of the multi-shell cytokine network fuels cancer in aged people. Bioessays 34:40-49.
    • (2012) Bioessays , vol.34 , pp. 40-49
    • Bonafè, M.1    Storci, G.2    Franceschi, C.3
  • 6
    • 84880174251 scopus 로고    scopus 로고
    • Matrix metalloproteinases: Inflammatory regulators of cell behaviors in vascular formation and remodeling
    • Chen Q, Jin M, Yang F, Zhu J, Xiao Q, Zhang L. 2013. Matrix metalloproteinases: Inflammatory regulators of cell behaviors in vascular formation and remodeling. Mediat Inflamm 2013: 928315.
    • (2013) Mediat Inflamm , vol.2013 , pp. 928315
    • Chen, Q.1    Jin, M.2    Yang, F.3    Zhu, J.4    Xiao, Q.5    Zhang, L.6
  • 7
    • 33748794547 scopus 로고    scopus 로고
    • Theoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug combination studies
    • Chou TC. 2006. Theoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug combination studies. Pharm Rev 58:621-681.
    • (2006) Pharm Rev , vol.58 , pp. 621-681
    • Chou, T.C.1
  • 9
    • 77949881221 scopus 로고    scopus 로고
    • The senescence-associated secretory phenotype: the dark side of tumour suppression
    • Coppé JP, Desprez PY, Krtolica A, Campisi J. 2010. The senescence-associated secretory phenotype: the dark side of tumour suppression. Annu Rev Pathol 5:99-118.
    • (2010) Annu Rev Pathol , vol.5 , pp. 99-118
    • Coppé, J.P.1    Desprez, P.Y.2    Krtolica, A.3    Campisi, J.4
  • 11
    • 33845654683 scopus 로고    scopus 로고
    • Role of carbonic anhydrases in the progression of renal cell carcinoma subtypes: Proposal of a unified hypothesis
    • Dorai T, Sawczuk I, Pastorek J, Wiernik PH, Dutcher JP. 2006. Role of carbonic anhydrases in the progression of renal cell carcinoma subtypes: Proposal of a unified hypothesis. Cancer Invest 8:754-779.
    • (2006) Cancer Invest , vol.8 , pp. 754-779
    • Dorai, T.1    Sawczuk, I.2    Pastorek, J.3    Wiernik, P.H.4    Dutcher, J.P.5
  • 12
    • 32944469305 scopus 로고    scopus 로고
    • MMPs and ADAMTs: Functional studies
    • Flannery CR. 2006. MMPs and ADAMTs: Functional studies. Front Biosci 11:544-569.
    • (2006) Front Biosci , vol.11 , pp. 544-569
    • Flannery, C.R.1
  • 14
    • 47149099173 scopus 로고    scopus 로고
    • The cross-talk between NF-κB and HIF-1: Further evidence for a significant liaison
    • Görlach A, Bonello S. 2008. The cross-talk between NF-κB and HIF-1: Further evidence for a significant liaison. Biochem J 412:e17-e19.
    • (2008) Biochem J , vol.412
    • Görlach, A.1    Bonello, S.2
  • 17
    • 84874299961 scopus 로고    scopus 로고
    • Contrasting hypoxic effects on breast cancer stem cell hierarchy is dependent on ERα status
    • Harrison H, Rogerson L, Gregson HJ, Brennan KR, Clarke RB, Landberg G. 2013. Contrasting hypoxic effects on breast cancer stem cell hierarchy is dependent on ERα status. Cancer Res 15:1420-1433.
    • (2013) Cancer Res , vol.15 , pp. 1420-1433
    • Harrison, H.1    Rogerson, L.2    Gregson, H.J.3    Brennan, K.R.4    Clarke, R.B.5    Landberg, G.6
  • 18
    • 82555181276 scopus 로고    scopus 로고
    • Exosome signaling in mammary gland development and cancer
    • Hendrix A, Hume AN. 2011. Exosome signaling in mammary gland development and cancer. Int J Dev Biol 55:879-887.
    • (2011) Int J Dev Biol , vol.55 , pp. 879-887
    • Hendrix, A.1    Hume, A.N.2
  • 20
    • 80053401068 scopus 로고    scopus 로고
    • Breast cancer stem cells, cytokine networks, and the tumour microenvironment
    • Korkaya H, Liu S, Wicha MS. 2011. Breast cancer stem cells, cytokine networks, and the tumour microenvironment. J Clin Invest 3:3804-3809.
    • (2011) J Clin Invest , vol.3 , pp. 3804-3809
    • Korkaya, H.1    Liu, S.2    Wicha, M.S.3
  • 21
    • 84872246916 scopus 로고    scopus 로고
    • The role of peroxisome proliferator-activated receptor-γ in breast cancer
    • Kotta-Loizou I, Giaginis C, Theocharis S. 2012. The role of peroxisome proliferator-activated receptor-γ in breast cancer. Anticancer Agents Med Chem 12:1025-1044.
    • (2012) Anticancer Agents Med Chem , vol.12 , pp. 1025-1044
    • Kotta-Loizou, I.1    Giaginis, C.2    Theocharis, S.3
  • 23
    • 77957591579 scopus 로고    scopus 로고
    • Targeting breast cancer stem cells
    • Liu S, Wicha MS. 2010. Targeting breast cancer stem cells. J Clin Oncol 28:4006-4012.
    • (2010) J Clin Oncol , vol.28 , pp. 4006-4012
    • Liu, S.1    Wicha, M.S.2
  • 24
    • 79955490807 scopus 로고    scopus 로고
    • Targeting tumour hypoxia: suppression of breast tumour growth and metastasis by novel carbonic anhydrase IX inhibitors
    • Lou Y, McDonald PC, Oloumi A, Chia S, Ostlund C, et al. 2011. Targeting tumour hypoxia: suppression of breast tumour growth and metastasis by novel carbonic anhydrase IX inhibitors. Cancer Res 71:3364-3376.
    • (2011) Cancer Res , vol.71 , pp. 3364-3376
    • Lou, Y.1    McDonald, P.C.2    Oloumi, A.3    Chia, S.4    Ostlund, C.5
  • 25
    • 84876577003 scopus 로고    scopus 로고
    • Nuclear control of the inflammatory response in mammals by peroxisome proliferator-activated receptors
    • Mandard S, Patsouris D. 2013. Nuclear control of the inflammatory response in mammals by peroxisome proliferator-activated receptors. PPAR Res 2013:613864.
    • (2013) PPAR Res , vol.2013 , pp. 613864
    • Mandard, S.1    Patsouris, D.2
  • 27
    • 65949117036 scopus 로고    scopus 로고
    • PPARγ and RXR ligands act sinergistically as potent antineoplastic agents in vitro and in vivo glioma models
    • Papi A, Tatenhorst L, Terwel D, Hermes M, Kummer MP, Orlandi M, Heneka MT. 2009. PPARγ and RXR ligands act sinergistically as potent antineoplastic agents in vitro and in vivo glioma models. J Neurochem 109:1779-1790.
    • (2009) J Neurochem , vol.109 , pp. 1779-1790
    • Papi, A.1    Tatenhorst, L.2    Terwel, D.3    Hermes, M.4    Kummer, M.P.5    Orlandi, M.6    Heneka, M.T.7
  • 28
    • 77956229623 scopus 로고    scopus 로고
    • RXRγ and PPARγ Ligands in Combination to Inhibit Proliferation and Invasiveness in Colon Cancer Cells
    • Papi A, Rocchi P, Ferreri AM, Orlandi M. 2010. RXRγ and PPARγ Ligands in Combination to Inhibit Proliferation and Invasiveness in Colon Cancer Cells. Cancer Lett 297:65-72.
    • (2010) Cancer Lett , vol.297 , pp. 65-72
    • Papi, A.1    Rocchi, P.2    Ferreri, A.M.3    Orlandi, M.4
  • 30
    • 84872861339 scopus 로고    scopus 로고
    • Peroxisome proliferator activated receptor-α/hypoxia inducible factor-1α interplay sustains carbonic anhydrase IX and apolipoprotein E expression in breast cancer stem cells
    • Papi A, Storci G, Guarnieri T, De Carolis S, Bertoni S, Avenia N, Sanguinetti A, Sidoni A, Santini D, Ceccarelli C, et al. 2013. Peroxisome proliferator activated receptor-α/hypoxia inducible factor-1α interplay sustains carbonic anhydrase IX and apolipoprotein E expression in breast cancer stem cells. Plos One 8:e54968.
    • (2013) Plos One , vol.8
    • Papi, A.1    Storci, G.2    Guarnieri, T.3    De Carolis, S.4    Bertoni, S.5    Avenia, N.6    Sanguinetti, A.7    Sidoni, A.8    Santini, D.9    Ceccarelli, C.10
  • 33
    • 84857641358 scopus 로고    scopus 로고
    • The role of peroxisome proliferator-activated receptors in carcinogenesis and chemoprevention
    • Peters JM, Shah YM, Gonzalez FJ. 2012. The role of peroxisome proliferator-activated receptors in carcinogenesis and chemoprevention. Nat Rev Cancer 12:181-195.
    • (2012) Nat Rev Cancer , vol.12 , pp. 181-195
    • Peters, J.M.1    Shah, Y.M.2    Gonzalez, F.J.3
  • 34
    • 84861125111 scopus 로고    scopus 로고
    • Molecular mechanisms regulating matrix metalloproteinases
    • Piperi C, Papavassiliou AG. 2012. Molecular mechanisms regulating matrix metalloproteinases. Curr Top Med Chem 12:1095-1112.
    • (2012) Curr Top Med Chem , vol.12 , pp. 1095-1112
    • Piperi, C.1    Papavassiliou, A.G.2
  • 36
    • 40949142209 scopus 로고    scopus 로고
    • The role of hypoxia-inducible factors in tumourigenesis
    • Rankin EB, Giaccia AJ. 2011. The role of hypoxia-inducible factors in tumourigenesis. Cell Death Differ 15:678-685.
    • (2011) Cell Death Differ , vol.15 , pp. 678-685
    • Rankin, E.B.1    Giaccia, A.J.2
  • 38
    • 70349976210 scopus 로고    scopus 로고
    • MicroRNAs: Novel regulators in the hallmarks of human cancer
    • Ruan K, Fang X, Ouyang G. 2009. MicroRNAs: Novel regulators in the hallmarks of human cancer. Cancer Lett. 28:116-126.
    • (2009) Cancer Lett. , vol.28 , pp. 116-126
    • Ruan, K.1    Fang, X.2    Ouyang, G.3
  • 39
    • 80053974912 scopus 로고    scopus 로고
    • Roles of metalloproteases in metastatic niche
    • Rucci N, Sanità P, Angelucci A. 2011. Roles of metalloproteases in metastatic niche. Curr Mol Med 11:609-622.
    • (2011) Curr Mol Med , vol.11 , pp. 609-622
    • Rucci, N.1    Sanità, P.2    Angelucci, A.3
  • 40
    • 80053012538 scopus 로고    scopus 로고
    • Functional heterogeneity of breast fibroblasts is defined by a prostaglandin secretory phenotype that promotes expansion of cancer-stem like cells
    • Rudnick JA, Arendt LM, Klebba I, Hinds JW, et al. 2011. Functional heterogeneity of breast fibroblasts is defined by a prostaglandin secretory phenotype that promotes expansion of cancer-stem like cells. PLoS One. 6:e24605.
    • (2011) PLoS One. , vol.6
    • Rudnick, J.A.1    Arendt, L.M.2    Klebba, I.3    Hinds, J.W.4
  • 41
    • 80051752025 scopus 로고    scopus 로고
    • MicroRNA 130 family regulates the hypoxia response signal through the P-body protein DDX6
    • Saito K, Kondo E, Matsushita M. 2011. MicroRNA 130 family regulates the hypoxia response signal through the P-body protein DDX6. Nucleic Acids Res 39:6086-6099.
    • (2011) Nucleic Acids Res , vol.39 , pp. 6086-6099
    • Saito, K.1    Kondo, E.2    Matsushita, M.3
  • 45
    • 84864925226 scopus 로고    scopus 로고
    • The key to unlocking the chemotherapeutic potential of PPARγ ligands: Having the right combination
    • Skelhorne-Gross G, Nicol CJ. 2012. The key to unlocking the chemotherapeutic potential of PPARγ ligands: Having the right combination. PPAR Res 946943.
    • (2012) PPAR Res , pp. 946943
    • Skelhorne-Gross, G.1    Nicol, C.J.2
  • 48
    • 77956264919 scopus 로고    scopus 로고
    • A novel nanoparticle drug delivery system: The anti-inflammatory activity of curcumin is enhanced when encapsulated in exosomes
    • Sun D, Zhuang X, Xiang X, Liu Y, Zhang S, Liu C, Barnes S, Grizzle W, Miller D, Zhang HG. 2010. A novel nanoparticle drug delivery system: The anti-inflammatory activity of curcumin is enhanced when encapsulated in exosomes. Mol Ther 18:1606-1614.
    • (2010) Mol Ther , vol.18 , pp. 1606-1614
    • Sun, D.1    Zhuang, X.2    Xiang, X.3    Liu, Y.4    Zhang, S.5    Liu, C.6    Barnes, S.7    Grizzle, W.8    Miller, D.9    Zhang, H.G.10
  • 49
    • 67449132372 scopus 로고    scopus 로고
    • Therapeutic potential of "rexinoids" in cancer prevention and treatment
    • Tanaka T, De Luca LM. 2009. Therapeutic potential of "rexinoids" in cancer prevention and treatment. Cancer Res 12:4945-4957.
    • (2009) Cancer Res , vol.12 , pp. 4945-4957
    • Tanaka, T.1    De Luca, L.M.2
  • 51
    • 0345643514 scopus 로고    scopus 로고
    • Regulation of matrix metalloproteinase expression in tumour invasion
    • Westermarck J, Kähäri VM. 1999. Regulation of matrix metalloproteinase expression in tumour invasion. FASEB J 13:781-792.
    • (1999) FASEB J , vol.13 , pp. 781-792
    • Westermarck, J.1    Kähäri, V.M.2
  • 52
    • 78149473681 scopus 로고    scopus 로고
    • Hypoxia-induced mitogenic factor (HIMF/FIZZ1/RELMalpha) increases lung inflammation and activates pulmonary microvascular endothelial cells via an IL-4-dependent mechanism
    • Yamaji-Kegan K, Su Q, Angelini DJ, Myers AC, Cheadle C, Johns RA. 2010. Hypoxia-induced mitogenic factor (HIMF/FIZZ1/RELMalpha) increases lung inflammation and activates pulmonary microvascular endothelial cells via an IL-4-dependent mechanism. J Immunol 185:5539-5548.
    • (2010) J Immunol , vol.185 , pp. 5539-5548
    • Yamaji-Kegan, K.1    Su, Q.2    Angelini, D.J.3    Myers, A.C.4    Cheadle, C.5    Johns, R.A.6
  • 53
    • 35148854599 scopus 로고    scopus 로고
    • Hypoxia is a potential risk factor for chronic inflammation and adiponectin reduction in adipose tissue of ob/ob and dietary obese mice
    • Ye J, Gao Z, Yin J, He Q. 2007. Hypoxia is a potential risk factor for chronic inflammation and adiponectin reduction in adipose tissue of ob/ob and dietary obese mice. Am J Physiol Endocrinol Metab 293:1118-1128.
    • (2007) Am J Physiol Endocrinol Metab , vol.293 , pp. 1118-1128
    • Ye, J.1    Gao, Z.2    Yin, J.3    He, Q.4
  • 54
    • 79961244975 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors and cancer: Challenges and opportunities
    • Youssef J, Badr M. 2011. Peroxisome proliferator-activated receptors and cancer: Challenges and opportunities. Br J Pharmacol 164:68-82.
    • (2011) Br J Pharmacol , vol.164 , pp. 68-82
    • Youssef, J.1    Badr, M.2
  • 55
    • 9144242586 scopus 로고    scopus 로고
    • Divergent effects of peroxisome proliferator-activated receptor gamma agonists and tumor necrosis factor alpha on adipocyte ApoE expression
    • Yue L, Rasouli N, Ranganathan G, Kern PA, Mazzone T. 2004. Divergent effects of peroxisome proliferator-activated receptor gamma agonists and tumor necrosis factor alpha on adipocyte ApoE expression. J Biol Chem 279:47626-47632.
    • (2004) J Biol Chem , vol.279 , pp. 47626-47632
    • Yue, L.1    Rasouli, N.2    Ranganathan, G.3    Kern, P.A.4    Mazzone, T.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.