Formulation optimization and in vivo proof-of-concept study of thermosensitive liposomes balanced by phospholipid, elastin-like polypeptide, and cholesterol

PLoS ONE

Volumn 9, Issue 7, 2014, Pages

  Park, Sun Min ^a   Cha, Jae Min ^a   Nam, Jungyong ^a   Kim, Min Sang ^a   Park, Sang Jun ^a   Park, Eun Sung ^a   Lee, Hwankyu ^b   Kim, Hyun Ryoung ^a  

^a Samsung Advanced Institute of Technology (SAIT)   (South Korea)

^b Dankook University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

1,2 DISTEAROYL SN GLYCERO 3 PHOSPHOETHANOLAMINE N [METHOXY(POLYETHYLENEGLYCOL) 2000]; CHOLESTEROL; DIPALMITOYLPHOSPHATIDYLCHOLINE; DOXORUBICIN; ELASTIN; LIPOSOME; PHOSPHOLIPID; UNCLASSIFIED DRUG; ANTINEOPLASTIC ANTIBIOTIC; LIPID BILAYER; NANOPARTICLE; PEPTIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST TUMOR; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; DIFFUSION COEFFICIENT; DRUG ACCUMULATION; DRUG DELIVERY SYSTEM; DRUG DESIGN; DRUG EFFECT; DRUG EFFICACY; DRUG FORMULATION; HEAT SENSITIVITY; HYPERTHERMIA; IN VITRO STUDY; IN VIVO STUDY; LIPID BILAYER; MALE; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; PERMEABILITY; PROCESS OPTIMIZATION; TEMPERATURE DEPENDENCE; THERMAL STIMULATION; THERMOREGULATION; THERMOSTABILITY; TUMOR CELL LINE; ANIMAL; CHEMISTRY; DISEASE MODEL; DRUG RELEASE; DRUG SCREENING; HUMAN; MEDICINAL CHEMISTRY; MOLECULAR DOCKING; PARTICLE SIZE; THERMODYNAMICS; TRANSITION TEMPERATURE; ULTRASTRUCTURE;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; CHEMISTRY, PHARMACEUTICAL; CHOLESTEROL; DISEASE MODELS, ANIMAL; DOXORUBICIN; DRUG DELIVERY SYSTEMS; DRUG LIBERATION; HUMANS; LIPID BILAYERS; LIPOSOMES; MALE; MICE; MOLECULAR DOCKING SIMULATION; NANOPARTICLES; PARTICLE SIZE; PEPTIDES; PHOSPHOLIPIDS; THERMODYNAMICS; TRANSITION TEMPERATURE; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84904865534     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0103116     Document Type: Article

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