Methylation differences at the HLA-DRB1 locus in CD4+ T-Cells are associated with multiple sclerosis

Multiple Sclerosis Journal

Volumn 20, Issue 8, 2014, Pages 1033-1041

  Graves, M C ^a   Benton, M ^b,c   Lea, R A ^a,b   Boyle, M ^d   Tajouri, L ^e   Macartney Coxson, D ^c   Scott, R J ^a,f   Lechner Scott, J ^a,d  

^a HUNTER MEDICAL RESEARCH INSTITUTE   (Australia)

^b GRIFFITH UNIVERSITY   (Australia)

^c INSTITUTE OF ENVIRONMENTAL SCIENCE AND RESEARCH   (New Zealand)

^d JOHN HUNTER HOSPITAL   (Australia)

^e BOND UNIVERSITY   (Australia)

^f JOHN HUNTER HOSPITAL   (Australia)

Author keywords

Epigenetics; genetics; immunology; methylation; multiple sclerosis

Indexed keywords

CD4 ANTIGEN; HLA DRB1 ANTIGEN;

ADULT; ARTICLE; CD4+ T LYMPHOCYTE; CLINICAL ARTICLE; CONTROLLED STUDY; CPG ISLAND; DNA METHYLATION; ENVIRONMENTAL EXPOSURE; EPIGENETICS; FEMALE; GENE; GENE LOCUS; HLA DRB1 GENE; HUMAN; MALE; MULTIPLE SCLEROSIS; COHORT ANALYSIS; DISEASE ASSOCIATION; GENETIC ASSOCIATION; GENETIC RISK; GENETIC SUSCEPTIBILITY; HAPLOTYPE; HUMAN CELL; 3' UNTRANSLATED REGION; 5' UNTRANSLATED REGION; ADOLESCENT; CASE CONTROL STUDY; GENETIC ASSOCIATION STUDY; GENETIC EPIGENESIS; GENETIC PREDISPOSITION; GENETICS; IMMUNOLOGY; MIDDLE AGED; PHENOTYPE; RISK FACTOR; YOUNG ADULT;

3' UNTRANSLATED REGIONS; 5' UNTRANSLATED REGIONS; ADOLESCENT; ADULT; CASE-CONTROL STUDIES; CD4-POSITIVE T-LYMPHOCYTES; CPG ISLANDS; DNA METHYLATION; EPIGENESIS, GENETIC; FEMALE; GENETIC ASSOCIATION STUDIES; GENETIC PREDISPOSITION TO DISEASE; HLA-DRB1 CHAINS; HUMANS; MALE; MIDDLE AGED; MULTIPLE SCLEROSIS, RELAPSING-REMITTING; PHENOTYPE; RISK FACTORS; YOUNG ADULT;

EID: 84904820156     PISSN: 13524585     EISSN: 14770970     Source Type: Journal    
DOI: 10.1177/1352458513516529     Document Type: Article

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