-
1
-
-
77956262278
-
Multiple sclerosis genetics-is the glass half full, or half empty?
-
Oksenberg JR, Baranzini SE. Multiple sclerosis genetics-is the glass half full, or half empty? Nat Rev Neurol 2010; 6: 429-437.
-
(2010)
Nat Rev Neurol
, vol.6
, pp. 429-437
-
-
Oksenberg, J.R.1
Baranzini, S.E.2
-
2
-
-
34548299105
-
Risk alleles for multiple sclerosis identified by a genomewide study
-
The International Multiple Sclerosis Genetics Consortium
-
The International Multiple Sclerosis Genetics Consortium. Risk alleles for multiple sclerosis identified by a genomewide study. N Eng J Med 2007; 357: 851-862.
-
(2007)
N Eng J Med
, vol.357
, pp. 851-862
-
-
-
3
-
-
67649876123
-
Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci
-
De Jager PL, Jia X, Wang J, de Bakker PIW, Ottoboni L, Aggarwal NT et al. Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci. Nat Genet 2009; 41: 776-782.
-
(2009)
Nat Genet
, vol.41
, pp. 776-782
-
-
De Jager, P.L.1
Jia, X.2
Wang, J.3
De Bakker Piw4
Ottoboni, L.5
Aggarwal, N.T.6
-
4
-
-
77954886757
-
IL12A, MPHOSPH9/CDK2AP1 and RSG1 are novel multiple sclerosis susceptibility loci
-
The International Multiple Sclerosis Genetics Consortium
-
The International Multiple Sclerosis Genetics Consortium. IL12A, MPHOSPH9/CDK2AP1 and RSG1 are novel multiple sclerosis susceptibility loci. Genes Immun 2010; 11: 397-405.
-
(2010)
Genes Immun
, vol.11
, pp. 397-405
-
-
-
5
-
-
33644797572
-
Glutamatemediated glial injury: Mechanisms and clinical importance
-
Matute C, Domercq M, Sánchez-Gómez MV. Glutamatemediated glial injury: mechanisms and clinical importance. Glia 2006; 53: 212-224.
-
(2006)
Glia
, vol.53
, pp. 212-224
-
-
Matute, C.1
Domercq, M.2
Sánchez-Gómez, M.V.3
-
6
-
-
34548368541
-
Variation in interleukin 7 receptor α chain (IL7R) influences risk of multiple sclerosis
-
DOI 10.1038/ng2106, PII NG2106
-
Lundmark F, Duvefelt K, Iacobaeus E, Kockum I, Wallström E, Khademi M et al. Variation in interleukin 7 receptor a chain (IL7R) influences risk of multiple sclerosis. Nat Genet 2007; 39: 1108-1113. (Pubitemid 47340654)
-
(2007)
Nature Genetics
, vol.39
, Issue.9
, pp. 1108-1113
-
-
Lundmark, F.1
Duvefelt, K.2
Iacobaeus, E.3
Kockum, I.4
Wallstrom, E.5
Khademi, M.6
Oturai, A.7
Ryder, L.P.8
Saarela, J.9
Harbo, H.F.10
Celius, E.G.11
Salter, H.12
Olsson, T.13
Hillert, J.14
-
7
-
-
39049159767
-
IL7RA polymorphisms and susceptibility to multiple sclerosis [18]
-
DOI 10.1056/NEJMc0707553
-
O'Doherty C, Kantarci O, Vandenbroeck K. IL7RA polymorphisms and susceptibility to multiple sclerosis. N Eng J Med 2008; 358: 753-754. (Pubitemid 351240775)
-
(2008)
New England Journal of Medicine
, vol.358
, Issue.7
, pp. 753-754
-
-
O'Doherty, C.1
Kantarci, O.2
Vandenbroeck, K.3
-
8
-
-
59149093148
-
The expanding genetic overlap between multiple sclerosis and type i diabetes
-
The International Multiple Sclerosis Genetics Consortium
-
The International Multiple Sclerosis Genetics Consortium. The expanding genetic overlap between multiple sclerosis and type I diabetes. Genes Immun 2009; 10: 11-14.
-
(2009)
Genes Immun
, vol.10
, pp. 11-14
-
-
-
9
-
-
78649354194
-
Differential expression of SOCS1 in macrophages in relapsing-remitting and chronic EAE and its role in disease severity
-
Berard JL, Kerr BJ, Johnson HM, David S. Differential expression of SOCS1 in macrophages in relapsing-remitting and chronic EAE and its role in disease severity. Glia 2010; 58: 1816-1826.
-
(2010)
Glia
, vol.58
, pp. 1816-1826
-
-
Berard, J.L.1
Kerr, B.J.2
Johnson, H.M.3
David, S.4
-
11
-
-
18744407587
-
Evidence of elevated glutamate in multiple sclerosis using magnetic resonance spectroscopy at 3 T
-
DOI 10.1093/brain/awh467
-
Srinivasan R, Sailasuta N, Hurd R, Nelson S, Pelletier D. Evidence of elevated glutamate in multiple sclerosis using magnetic resonance spectroscopy at 3T. Brain 2005; 128: 1016-1025. (Pubitemid 40675457)
-
(2005)
Brain
, vol.128
, Issue.5
, pp. 1016-1025
-
-
Srinivasan, R.1
Sailasuta, N.2
Hurd, R.3
Nelson, S.4
Pelletier, D.5
-
12
-
-
77956369535
-
Genetic variation influences glutamate concentrations in brains of patients with multiple sclerosis
-
Baranzini SE, Srinivasan R, Khankhanian P, Okuda DT, Nelson SJ, Matthews PM et al. Genetic variation influences glutamate concentrations in brains of patients with multiple sclerosis. Brain 2010; 133: 2603-2611.
-
(2010)
Brain
, vol.133
, pp. 2603-2611
-
-
Baranzini, S.E.1
Srinivasan, R.2
Khankhanian, P.3
Okuda, D.T.4
Nelson, S.J.5
Matthews, P.M.6
-
13
-
-
40849094272
-
Genome-wide pharmacogenomic analysis of the response to interferon beta therapy in multiple sclerosis
-
DOI 10.1001/archneurol.2008.47
-
Byun E, Caillier SJ, Montalban X, Villoslada P, Fernández O, Brassat D et al. Genome-wide pharmacogenomic analysis of the response to interferon beta therapy in multiple sclerosis. Arch Neurol 2008; 65: 337-344. (Pubitemid 351398518)
-
(2008)
Archives of Neurology
, vol.65
, Issue.3
, pp. 337-344
-
-
Byun, E.1
Caillier, S.J.2
Montalban, X.3
Villoslada, P.4
Fernandez, O.5
Brassat, D.6
Comabella, M.7
Wang, J.8
Barcellos, L.F.9
Baranzini, S.E.10
Oksenberg, J.R.11
-
14
-
-
68549085471
-
Genome-wide scan of 500 000 singlenucleotide polymorphisms among responders and nonresponders to interferon beta therapy in multiple sclerosis
-
Comabella M, Craig DW, Morcillo-Suárez C, Río J, Navarro A, Fernández M et al. Genome-wide scan of 500 000 singlenucleotide polymorphisms among responders and nonresponders to interferon beta therapy in multiple sclerosis. Arch Neurol 2009; 66: 972-978.
-
(2009)
Arch Neurol
, vol.66
, pp. 972-978
-
-
Comabella, M.1
Craig, D.W.2
Morcillo-Suárez, C.3
Río, J.4
Navarro, A.5
Fernández, M.6
-
16
-
-
0036142847
-
Regulation of signal transducer and activator of transcription and suppressor of cytokine-signaling gene expression in the brain of mice with astrocyte-targeted production of interleukin-12 or experimental autoimmune encephalomyelitis
-
Maier J, Kincaid C, Pagenstecher A, Campbell IL. Regulation of signal transducer and activator of transcription and suppressor of cytokine-signaling gene expression in the brain of mice with astrocyte-targeted production of interleukin-12 or experimental autoimmune encephalomyelitis. Am J Pathol 2002; 160: 271-288. (Pubitemid 34052288)
-
(2002)
American Journal of Pathology
, vol.160
, Issue.1
, pp. 271-288
-
-
Maier, J.1
Kincaid, C.2
Pagenstecher, A.3
Campbell, I.L.4
-
17
-
-
31544435227
-
Differential expression of suppressors of cytokine signaling-1 and -3 and related cytokines in central nervous system during remitting versus non-remitting forms of experimental autoimmune encephalomyelitis
-
DOI 10.1093/intimm/dxh373
-
Stark JL, Cross AH. Differential expression of suppressors of cytokine signaling-1 and-3 and related cytokines in central nervous system during remitting versus non-remitting forms of experimental autoimmune encephalomyelitis. Int Immunol 2006; 18: 347-353. (Pubitemid 43160147)
-
(2006)
International Immunology
, vol.18
, Issue.2
, pp. 347-353
-
-
Stark, J.L.1
Cross, A.H.2
-
18
-
-
33847223756
-
Interferon-gamma-oligodendrocyte interactions in the regulation of experimental autoimmune encephalomyelitis
-
Balabanov R, Strand K, Goswami R, McMahon E, Begolka W, Miller SD et al. Interferon-gamma-oligodendrocyte interactions in the regulation of experimental autoimmune encephalomyelitis. J Neurosci 2007; 27: 2013-2024.
-
(2007)
J Neurosci
, vol.27
, pp. 2013-2024
-
-
Balabanov, R.1
Strand, K.2
Goswami, R.3
McMahon, E.4
Begolka, W.5
Miller, S.D.6
-
19
-
-
26844548688
-
Treatment of mice with the suppressor of cytokine signaling-1 mimetic peptide, tyrosine kinase inhibitor peptide, prevents development of the acute form of experimental allergic encephalomyelitis and induces stable remission in the chronic relapsing/remitting form
-
Mujitaba MG, Flowers LO, Patel CB, Patel RA, Haider MI, Johnson HM. Treatment of mice with the suppressor of cytokine signaling-1 mimetic peptide, tyrosine kinase inhibitor peptide, prevents development of the acute form of experimental allergic encephalomyelitis and induces stable remission in the chronic relapsing/remitting form. J Immunol 2005; 175: 5077-5086. (Pubitemid 41456391)
-
(2005)
Journal of Immunology
, vol.175
, Issue.8
, pp. 5077-5086
-
-
Mujtaba, M.G.1
Flowers, L.O.2
Patel, C.B.3
Patel, R.A.4
Haider, M.I.5
Johnson, H.M.6
-
20
-
-
44849115688
-
Loss of suppressor of cytokine signaling 1 in helper T cells leads to defective Th17 differentiation by enhancing antagonistic effects of IFN-gamma on STAT3 and Smads
-
Tanaka K, Ichiyama K, Hashimoto M, Yoshida H, Takimoto T, Takaesu G et al. Loss of suppressor of cytokine signaling 1 in helper T cells leads to defective Th17 differentiation by enhancing antagonistic effects of IFN-gamma on STAT3 and Smads. J Immunol 2008; 180: 3746-3756.
-
(2008)
J Immunol
, vol.180
, pp. 3746-3756
-
-
Tanaka, K.1
Ichiyama, K.2
Hashimoto, M.3
Yoshida, H.4
Takimoto, T.5
Takaesu, G.6
-
21
-
-
59349092716
-
Functional SOCS1 polymorphisms are associated with variation in obesity in whites
-
Gylvin T, Ek J, Nolsøe R, Albrechtsen A, Andersen G, Bergholdt R et al. Functional SOCS1 polymorphisms are associated with variation in obesity in whites. Diabetes Obes Metab 2009; 11: 196-203.
-
(2009)
Diabetes Obes Metab
, vol.11
, pp. 196-203
-
-
Gylvin, T.1
Ek, J.2
Nolsøe, R.3
Albrechtsen, A.4
Andersen, G.5
Bergholdt, R.6
-
22
-
-
34247265510
-
Functional polymorphism in the suppressor of cytokine signaling 1 gene associated with adult asthma
-
DOI 10.1165/rcmb.2006-0090OC
-
Harada M, Nakahima K, Hirota T, Shimizu M, Doi S, Fujita K et al. Functional polymorphism in the suppressor of cytokine signaling 1 gene associated with adult asthma. Am J Respir Cell Mol Biol 2007; 36: 491-496. (Pubitemid 46623008)
-
(2007)
American Journal of Respiratory Cell and Molecular Biology
, vol.36
, Issue.4
, pp. 491-496
-
-
Harada, M.1
Nakashima, K.2
Hirota, T.3
Shimizu, M.4
Doi, S.5
Fujita, K.6
Shirakawa, T.7
Enomoto, T.8
Yoshikawa, M.9
Moriyama, H.10
Matsumoto, K.11
Saito, H.12
Suzuki, Y.13
Nakamura, Y.14
Tamari, M.15
-
23
-
-
77951626389
-
Genetic variation in the IL7RA/IL7 pathway increases multiple sclerosis susceptibility
-
Zuvich RL, McCauleu JL, Oksenberg JTR, Sawcer SJ, De Jager PL, IMSGC et al. Genetic variation in the IL7RA/IL7 pathway increases multiple sclerosis susceptibility. Hum Genet 2010; 127: 525-535.
-
(2010)
Hum Genet
, vol.127
, pp. 525-535
-
-
Zuvich, R.L.1
McCauleu, J.L.2
Jtr, O.3
Sawcer, S.J.4
Imsgc Pl D.Jager5
-
24
-
-
0028987573
-
Coordinate expression of the PRM1, PRM2, and TNP2 multigene locus in human testis
-
Wykes SM, Nelson JE, Visscher DW, Djakiew D, Krawetz SA. Coordinate expression of the PRM1, PRM2, and TNP2 multigene locus in human testis. DNA Cell Biol 1995; 14: 155-161.
-
(1995)
DNA Cell Biol
, vol.14
, pp. 155-161
-
-
Wykes, S.M.1
Nelson, J.E.2
Visscher, D.W.3
Djakiew, D.4
Krawetz, S.A.5
-
25
-
-
78650673588
-
IL-22RA2 associates with multiple sclerosis and macrophage effector mechanisms in experimental neuroinflammation
-
Beyeen AD, Adzemovic MZ, Ockinger J, Stridh P, Becanovic K, Laaksonen H et al. IL-22RA2 associates with multiple sclerosis and macrophage effector mechanisms in experimental neuroinflammation. J Immunol 2010; 185: 6883-6890.
-
(2010)
J Immunol
, vol.185
, pp. 6883-6890
-
-
Beyeen, A.D.1
Adzemovic, M.Z.2
Ockinger, J.3
Stridh, P.4
Becanovic, K.5
Laaksonen, H.6
-
26
-
-
78049347495
-
A genomewide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1
-
Genetic Analysis of Psoriasis Consortium et al
-
Genetic Analysis of Psoriasis Consortium et al. A genomewide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1. Nat Genet 2010; 42: 985-990.
-
(2010)
Nat Genet
, vol.42
, pp. 985-990
-
-
-
28
-
-
77949797723
-
Aspects of observing and claiming allele flips in association studies
-
Clarke GM, Cardon LR. Aspects of observing and claiming allele flips in association studies. Genet Epidemiol 2010; 34: 266-274.
-
(2010)
Genet Epidemiol
, vol.34
, pp. 266-274
-
-
Clarke, G.M.1
Cardon, L.R.2
-
29
-
-
70349629969
-
Replication analysis identifies TYK2 as a multiple sclerosis susceptibility factor
-
Ban M, Goris A, Lorentzen AR, Baker A, Mihalova T, Ingram G et al. Replication analysis identifies TYK2 as a multiple sclerosis susceptibility factor. Eur J Hum Genet 2009; 10: 1309-1313.
-
(2009)
Eur J Hum Genet
, vol.10
, pp. 1309-1313
-
-
Ban, M.1
Goris, A.2
Lorentzen, A.R.3
Baker, A.4
Mihalova, T.5
Ingram, G.6
-
30
-
-
78751649865
-
Validation of IRF5 as multiple sclerosis risk gene: Putative role in interferon beta therapy and human herpes virus-6 infection
-
Vandenbroeck K, Alloza I, Swaminathan B, Antigüedad A, Otaegui D, Olascoaga J et al. Validation of IRF5 as multiple sclerosis risk gene: putative role in interferon beta therapy and human herpes virus-6 infection. Genes Immun 2011; 12: 40-45.
-
(2011)
Genes Immun
, vol.12
, pp. 40-45
-
-
Vandenbroeck, K.1
Alloza, I.2
Swaminathan, B.3
Antigüedad, A.4
Otaegui, D.5
Olascoaga, J.6
-
31
-
-
45249112573
-
Interferon regulatory factor 5 (IRF5) gene variants are associated with multiple sclerosis in three distinct populations
-
DOI 10.1136/jmg.2007.055012
-
Kristjansdottir G, Sandling JK, Bonetti A, Roos IM, Milani L, Wang C et al. Interferon regulatory factor 5 (IRF5) gene variants are associated with multiple sclerosis in three distinct populations. J Med Genet 2008; 45: 362-369. (Pubitemid 351839477)
-
(2008)
Journal of Medical Genetics
, vol.45
, Issue.6
, pp. 362-369
-
-
Kristjansdottir, G.1
Sandling, J.K.2
Bonetti, A.3
Roos, I.M.4
Milani, L.5
Wang, C.6
Gustafsdottir, S.M.7
Sigurdsson, S.8
Lundmark, A.9
Tienari, P.J.10
Koivisto, K.11
Elovaara, I.12
Pirttila, T.13
Reunanen, M.14
Peltonen, L.15
Saarela, J.16
Hillert, J.17
Olsson, T.18
Landegren, U.19
Alcina, A.20
Fernandez, O.21
Leyva, L.22
Guerrero, M.23
Lucas, M.24
Izquierdo, G.25
Matesanz, F.26
Syvanen, A.-C.27
more..
-
32
-
-
0020686503
-
New diagnostic criteria for multiple sclerosis: Guidelines for research protocols
-
DOI 10.1002/ana.410130302
-
Poser CM, Paty DW, Scheinberg L, McDonald WI, Davis FA, Ebers GC et al. New diagnostic criteria for multiple sclerosis: guidelines for research protocols. Ann Neurol 1983; 13: 227-231. (Pubitemid 13158528)
-
(1983)
Annals of Neurology
, vol.13
, Issue.3
, pp. 227-231
-
-
Poser, C.M.1
Paty, D.W.2
Scheinberg, L.3
-
33
-
-
0034955141
-
Recommended diagnostic criteria for multiple sclerosis: Guidelines from the International Panel on the diagnosis of multiple sclerosis
-
MacDonald WI, Compston A, Edan G, Goodkin D, Hartung HP, Lublin FD et al. Recommended diagnostic criteria for multiple sclerosis: guidelines from the International Panel on the diagnosis of multiple sclerosis. Ann Neurol 2001; 50: 121-127.
-
(2001)
Ann Neurol
, vol.50
, pp. 121-127
-
-
MacDonald, W.I.1
Compston, A.2
Edan, G.3
Goodkin, D.4
Hartung, H.P.5
Lublin, F.D.6
-
34
-
-
34548292504
-
PLINK: A tool set for whole-genome association and population-based linkage analyses
-
DOI 10.1086/519795
-
Purcell S, Neale B, Todd-Brown K, Thomas L, Ferreira MA, Bender D et al. PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet 2007; 81: 559-575. (Pubitemid 47330214)
-
(2007)
American Journal of Human Genetics
, vol.81
, Issue.3
, pp. 559-575
-
-
Purcell, S.1
Neale, B.2
Todd-Brown, K.3
Thomas, L.4
Ferreira, M.A.R.5
Bender, D.6
Maller, J.7
Sklar, P.8
De Bakker, P.I.W.9
Daly, M.J.10
Sham, P.C.11
-
35
-
-
13444269543
-
Haploview: Analysis and visualization of LD and haplotype maps
-
DOI 10.1093/bioinformatics/bth457
-
Barrett JC, Fry B, Maller J, Daly MJ. Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics 2005; 21: 263-265. (Pubitemid 40202029)
-
(2005)
Bioinformatics
, vol.21
, Issue.2
, pp. 263-265
-
-
Barrett, J.C.1
Fry, B.2
Maller, J.3
Daly, M.J.4
-
36
-
-
31744435871
-
Joint analysis is more efficient than replication-based analysis for two-stage genome-wide association studies
-
DOI 10.1038/ng1706, PII NG1706
-
Skol AD, Scott LJ, Abecasis GR, Boehnke M. Joint analysis is more efficient than replication-based analysis for two-stage genome-wide association studies. Nat Genet 2006; 38: 209-213. (Pubitemid 43177235)
-
(2006)
Nature Genetics
, vol.38
, Issue.2
, pp. 209-213
-
-
Skol, A.D.1
Scott, L.J.2
Abecasis, G.R.3
Boehnke, M.4
-
37
-
-
57249114505
-
SNAP: A web-based tool for identification and annotation of proxy SNPs using HapMap
-
Johnson AD, Handsaker RE, Pulit SL, Nizzari MM, O'Donnell CJ, de Bakker PI. SNAP: a web-based tool for identification and annotation of proxy SNPs using HapMap. Bioinformatics 2008; 24: 2938-2939.
-
(2008)
Bioinformatics
, vol.24
, pp. 2938-2939
-
-
Johnson, A.D.1
Handsaker, R.E.2
Pulit, S.L.3
Nizzari, M.M.4
O'Donnell, C.J.5
De Bakker, P.I.6
|