-
1
-
-
77953394241
-
Multiple sclerosis: risk factors, prodromes, and potential causal pathways
-
Ramagopalan SV, Dobson R, Meier UC, Giovannoni G Multiple sclerosis: risk factors, prodromes, and potential causal pathways. Lancet Neurol 2010, 9:727-739.
-
(2010)
Lancet Neurol
, vol.9
, pp. 727-739
-
-
Ramagopalan, S.V.1
Dobson, R.2
Meier, U.C.3
Giovannoni, G.4
-
2
-
-
84862747867
-
The genetics of multiple sclerosis: an up-to-date review
-
Gourraud PA, Harbo HF, Hauser SL, Baranzini SE The genetics of multiple sclerosis: an up-to-date review. Immunol Rev 2012, 248:87-103.
-
(2012)
Immunol Rev
, vol.248
, pp. 87-103
-
-
Gourraud, P.A.1
Harbo, H.F.2
Hauser, S.L.3
Baranzini, S.E.4
-
3
-
-
0037154187
-
MTR discloses subtle changes in the normal-appearing tissue from relatives of patients with MS
-
Siger-Zajdel M, Filippi M, Selmaj K MTR discloses subtle changes in the normal-appearing tissue from relatives of patients with MS. Neurology 2002, 58:317-320.
-
(2002)
Neurology
, vol.58
, pp. 317-320
-
-
Siger-Zajdel, M.1
Filippi, M.2
Selmaj, K.3
-
4
-
-
33645776415
-
Imaging brain damage in first-degree relatives of sporadic and familial multiple sclerosis
-
De Stefano N, Cocco E, Lai M, et al. Imaging brain damage in first-degree relatives of sporadic and familial multiple sclerosis. Ann Neurol 2006, 59:634-639.
-
(2006)
Ann Neurol
, vol.59
, pp. 634-639
-
-
De Stefano, N.1
Cocco, E.2
Lai, M.3
-
5
-
-
62849110378
-
Incidental MRI anomalies suggestive of multiple sclerosis: the radiologically isolated syndrome
-
Okuda DT, Mowry EM, Beheshtian A, et al. Incidental MRI anomalies suggestive of multiple sclerosis: the radiologically isolated syndrome. Neurology 2009, 72:800-805.
-
(2009)
Neurology
, vol.72
, pp. 800-805
-
-
Okuda, D.T.1
Mowry, E.M.2
Beheshtian, A.3
-
6
-
-
1642524998
-
Multiple sclerosis trait: the premorbid stage of multiple sclerosis. A hypothesis
-
Poser CM Multiple sclerosis trait: the premorbid stage of multiple sclerosis. A hypothesis. Acta Neurol Scand 2004, 109:239-243.
-
(2004)
Acta Neurol Scand
, vol.109
, pp. 239-243
-
-
Poser, C.M.1
-
7
-
-
1642485676
-
Vernalization and epigenetics: how plants remember winter
-
Sung S, Amasino RM Vernalization and epigenetics: how plants remember winter. Curr Opin Plant Biol 2004, 7:4-10.
-
(2004)
Curr Opin Plant Biol
, vol.7
, pp. 4-10
-
-
Sung, S.1
Amasino, R.M.2
-
8
-
-
84856232984
-
Environmentally coordinated epigenetic silencing of FLC by protein and long noncoding RNA components
-
Kim DH, Sung S Environmentally coordinated epigenetic silencing of FLC by protein and long noncoding RNA components. Curr Opin Plant Biol 2012, 15:51-56.
-
(2012)
Curr Opin Plant Biol
, vol.15
, pp. 51-56
-
-
Kim, D.H.1
Sung, S.2
-
9
-
-
84863561552
-
Low relative humidity triggers RNA-directed de novo DNA methylation and suppression of genes controlling stomatal development
-
Tricker PJ, Gibbings JG, Rodriguez Lopez CM, Hadley P, Wilkinson MJ Low relative humidity triggers RNA-directed de novo DNA methylation and suppression of genes controlling stomatal development. J Exp Bot 2012, 63:3799-3813.
-
(2012)
J Exp Bot
, vol.63
, pp. 3799-3813
-
-
Tricker, P.J.1
Gibbings, J.G.2
Rodriguez Lopez, C.M.3
Hadley, P.4
Wilkinson, M.J.5
-
10
-
-
79960141859
-
Tissue-specific distribution of aberrant DNA methylation associated with maternal low-folate status in human neural tube defects
-
Chang H, Zhang T, Zhang Z, et al. Tissue-specific distribution of aberrant DNA methylation associated with maternal low-folate status in human neural tube defects. J Nutr Biochem 2011, 22:1172-1177.
-
(2011)
J Nutr Biochem
, vol.22
, pp. 1172-1177
-
-
Chang, H.1
Zhang, T.2
Zhang, Z.3
-
11
-
-
79953706343
-
Tobacco-smoking-related differential DNA methylation: 27K discovery and replication
-
Breitling LP, Yang R, Korn B, Burwinkel B, Brenner H Tobacco-smoking-related differential DNA methylation: 27K discovery and replication. Am J Hum Genet 2011, 88:450-457.
-
(2011)
Am J Hum Genet
, vol.88
, pp. 450-457
-
-
Breitling, L.P.1
Yang, R.2
Korn, B.3
Burwinkel, B.4
Brenner, H.5
-
12
-
-
23044514669
-
Epigenetic differences arise during the lifetime of monozygotic twins
-
Fraga MF, Ballestar E, Paz MF, et al. Epigenetic differences arise during the lifetime of monozygotic twins. Proc Natl Acad Sci USA 2005, 102:10604-10609.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 10604-10609
-
-
Fraga, M.F.1
Ballestar, E.2
Paz, M.F.3
-
13
-
-
84862979818
-
Distinct DNA methylomes of newborns and centenarians
-
Heyn H, Li N, Ferreira HJ, et al. Distinct DNA methylomes of newborns and centenarians. Proc Natl Acad Sci USA 2012, 109:10522-10527.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 10522-10527
-
-
Heyn, H.1
Li, N.2
Ferreira, H.J.3
-
14
-
-
33750957133
-
Increased citrullination of histone H3 in multiple sclerosis brain and animal models of demyelination: a role for tumor necrosis factor-induced peptidylarginine deiminase 4 translocation
-
Mastronardi FG, Wood DD, Mei J, et al. Increased citrullination of histone H3 in multiple sclerosis brain and animal models of demyelination: a role for tumor necrosis factor-induced peptidylarginine deiminase 4 translocation. J Neurosci 2006, 26:11387-11396.
-
(2006)
J Neurosci
, vol.26
, pp. 11387-11396
-
-
Mastronardi, F.G.1
Wood, D.D.2
Mei, J.3
-
15
-
-
79952272438
-
Changed histone acetylation patterns in normal-appearing white matter and early multiple sclerosis lesions
-
Pedre X, Mastronardi F, Bruck W, Lopez-Rodas G, Kuhlmann T, Casaccia P Changed histone acetylation patterns in normal-appearing white matter and early multiple sclerosis lesions. J Neurosci 2011, 31:3435-3445.
-
(2011)
J Neurosci
, vol.31
, pp. 3435-3445
-
-
Pedre, X.1
Mastronardi, F.2
Bruck, W.3
Lopez-Rodas, G.4
Kuhlmann, T.5
Casaccia, P.6
-
16
-
-
2542541258
-
Parent-of-origin effect in multiple sclerosis: observations in half-siblings
-
Ebers GC, Sadovnick AD, Dyment DA, Yee IM, Willer CJ, Risch N Parent-of-origin effect in multiple sclerosis: observations in half-siblings. Lancet 2004, 363:1773-1774.
-
(2004)
Lancet
, vol.363
, pp. 1773-1774
-
-
Ebers, G.C.1
Sadovnick, A.D.2
Dyment, D.A.3
Yee, I.M.4
Willer, C.J.5
Risch, N.6
-
17
-
-
0346688789
-
Multiple sclerosis in US veterans of the Vietnam era and later military service: race, sex, and geography
-
Wallin MT, Page WF, Kurtzke JF Multiple sclerosis in US veterans of the Vietnam era and later military service: race, sex, and geography. Ann Neurol 2004, 55:65-71.
-
(2004)
Ann Neurol
, vol.55
, pp. 65-71
-
-
Wallin, M.T.1
Page, W.F.2
Kurtzke, J.F.3
-
18
-
-
33749681309
-
Sex ratio of multiple sclerosis in Canada: a longitudinal study
-
Orton SM, Herrera BM, Yee IM, et al. Sex ratio of multiple sclerosis in Canada: a longitudinal study. Lancet Neurol 2006, 5:932-936.
-
(2006)
Lancet Neurol
, vol.5
, pp. 932-936
-
-
Orton, S.M.1
Herrera, B.M.2
Yee, I.M.3
-
19
-
-
64749094075
-
Increasing prevalence and incidence of multiple sclerosis in South East Wales
-
Hirst C, Ingram G, Pickersgill T, Swingler R, Compston DA, Robertson NP Increasing prevalence and incidence of multiple sclerosis in South East Wales. J Neurol Neurosurg Psychiatry 2009, 80:386-391.
-
(2009)
J Neurol Neurosurg Psychiatry
, vol.80
, pp. 386-391
-
-
Hirst, C.1
Ingram, G.2
Pickersgill, T.3
Swingler, R.4
Compston, D.A.5
Robertson, N.P.6
-
20
-
-
84862620252
-
Exploring the role of the epigenome in multiple sclerosis: a window onto cell-specific transcriptional potential
-
Kaliszewska A, De Jager PL Exploring the role of the epigenome in multiple sclerosis: a window onto cell-specific transcriptional potential. J Neuroimmunol 2012, 248:2-9.
-
(2012)
J Neuroimmunol
, vol.248
, pp. 2-9
-
-
Kaliszewska, A.1
De Jager, P.L.2
-
21
-
-
77952678006
-
Epigenetic control of neural precursor cell fate during development
-
Hirabayashi Y, Gotoh Y Epigenetic control of neural precursor cell fate during development. Nat Rev Neurosci 2010, 11:377-388.
-
(2010)
Nat Rev Neurosci
, vol.11
, pp. 377-388
-
-
Hirabayashi, Y.1
Gotoh, Y.2
-
22
-
-
77950867183
-
Epigenetic regulation of oligodendrocyte identity
-
Liu J, Casaccia P Epigenetic regulation of oligodendrocyte identity. Trends Neurosci 2010, 33:193-201.
-
(2010)
Trends Neurosci
, vol.33
, pp. 193-201
-
-
Liu, J.1
Casaccia, P.2
-
23
-
-
46249112085
-
Combinatorial patterns of histone acetylations and methylations in the human genome
-
Wang Z, Zang C, Rosenfeld JA, et al. Combinatorial patterns of histone acetylations and methylations in the human genome. Nat Genet 2008, 40:897-903.
-
(2008)
Nat Genet
, vol.40
, pp. 897-903
-
-
Wang, Z.1
Zang, C.2
Rosenfeld, J.A.3
-
24
-
-
33847076849
-
Chromatin modifications and their function
-
Kouzarides T Chromatin modifications and their function. Cell 2007, 128:693-705.
-
(2007)
Cell
, vol.128
, pp. 693-705
-
-
Kouzarides, T.1
-
25
-
-
84859893371
-
Histone methylation: a dynamic mark in health, disease and inheritance
-
Greer EL, Shi Y Histone methylation: a dynamic mark in health, disease and inheritance. Nat Rev Genet 2012, 13:343-357.
-
(2012)
Nat Rev Genet
, vol.13
, pp. 343-357
-
-
Greer, E.L.1
Shi, Y.2
-
26
-
-
84860215207
-
Molecular mechanisms and potential functions of histone demethylases
-
Kooistra SM, Helin K Molecular mechanisms and potential functions of histone demethylases. Nat Rev Mol Cell Biol 2012, 13:297-311.
-
(2012)
Nat Rev Mol Cell Biol
, vol.13
, pp. 297-311
-
-
Kooistra, S.M.1
Helin, K.2
-
27
-
-
79959829510
-
Histone arginine methylation
-
Di Lorenzo A, Bedford MT Histone arginine methylation. FEBS Lett 2011, 585:2024-2031.
-
(2011)
FEBS Lett
, vol.585
, pp. 2024-2031
-
-
Di Lorenzo, A.1
Bedford, M.T.2
-
28
-
-
84865190335
-
Peptidylarginine deiminase 2-catalyzed histone H3 arginine 26 citrullination facilitates estrogen receptor alpha target gene activation
-
Zhang X, Bolt M, Guertin MJ, et al. Peptidylarginine deiminase 2-catalyzed histone H3 arginine 26 citrullination facilitates estrogen receptor alpha target gene activation. Proc Natl Acad Sci USA 2012, 109:13331-13336.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 13331-13336
-
-
Zhang, X.1
Bolt, M.2
Guertin, M.J.3
-
29
-
-
83255192184
-
A peek into the complex realm of histone phosphorylation
-
Banerjee T, Chakravarti D A peek into the complex realm of histone phosphorylation. Mol Cell Biol 2011, 31:4858-4873.
-
(2011)
Mol Cell Biol
, vol.31
, pp. 4858-4873
-
-
Banerjee, T.1
Chakravarti, D.2
-
30
-
-
84869071444
-
Chromatin modification by SUMO-1 stimulates the promoters of translation machinery genes
-
Liu HW, Zhang J, Heine GF, et al. Chromatin modification by SUMO-1 stimulates the promoters of translation machinery genes. Nucleic Acids Res 2012, 40:10172-10186.
-
(2012)
Nucleic Acids Res
, vol.40
, pp. 10172-10186
-
-
Liu, H.W.1
Zhang, J.2
Heine, G.F.3
-
31
-
-
27944454433
-
Monoubiquitination of human histone H2B: the factors involved and their roles in HOX gene regulation
-
Zhu B, Zheng Y, Pham AD, et al. Monoubiquitination of human histone H2B: the factors involved and their roles in HOX gene regulation. Mol Cell 2005, 20:601-611.
-
(2005)
Mol Cell
, vol.20
, pp. 601-611
-
-
Zhu, B.1
Zheng, Y.2
Pham, A.D.3
-
32
-
-
65249105512
-
RAD6-mediated transcription-coupled H2B ubiquitylation directly stimulates H3K4 methylation in human cells
-
Kim J, Guermah M, Ginty RK, et al. RAD6-mediated transcription-coupled H2B ubiquitylation directly stimulates H3K4 methylation in human cells. Cell 2009, 137:459-471.
-
(2009)
Cell
, vol.137
, pp. 459-471
-
-
Kim, J.1
Guermah, M.2
Ginty, R.K.3
-
33
-
-
33751001725
-
Histone citrullination by protein arginine deiminase: is arginine methylation a green light or a roadblock?
-
Thompson PR, Fast W Histone citrullination by protein arginine deiminase: is arginine methylation a green light or a roadblock?. ACS Chem Biol 2006, 1:433-441.
-
(2006)
ACS Chem Biol
, vol.1
, pp. 433-441
-
-
Thompson, P.R.1
Fast, W.2
-
34
-
-
0344824404
-
Histone sumoylation is associated with transcriptional repression
-
Shiio Y, Eisenman RN Histone sumoylation is associated with transcriptional repression. Proc Natl Acad Sci USA 2003, 100:13225-13230.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 13225-13230
-
-
Shiio, Y.1
Eisenman, R.N.2
-
35
-
-
7244234099
-
Role of histone H2A ubiquitination in Polycomb silencing
-
Wang H, Wang L, Erdjument-Bromage H, et al. Role of histone H2A ubiquitination in Polycomb silencing. Nature 2004, 431:873-878.
-
(2004)
Nature
, vol.431
, pp. 873-878
-
-
Wang, H.1
Wang, L.2
Erdjument-Bromage, H.3
-
36
-
-
77958577154
-
Epigenetic modifiers are necessary but not sufficient for reprogramming non-myelinating cells into myelin gene-expressing cells
-
Liu J, Sandoval J, Doh ST, Cai L, Lopez-Rodas G, Casaccia P Epigenetic modifiers are necessary but not sufficient for reprogramming non-myelinating cells into myelin gene-expressing cells. PLoS One 2010, 5:13023.
-
(2010)
PLoS One
, vol.5
, pp. 13023
-
-
Liu, J.1
Sandoval, J.2
Doh, S.T.3
Cai, L.4
Lopez-Rodas, G.5
Casaccia, P.6
-
37
-
-
34447262102
-
The transcription factor Yin Yang 1 is essential for oligodendrocyte progenitor differentiation
-
He Y, Dupree J, Wang J, et al. The transcription factor Yin Yang 1 is essential for oligodendrocyte progenitor differentiation. Neuron 2007, 55:217-230.
-
(2007)
Neuron
, vol.55
, pp. 217-230
-
-
He, Y.1
Dupree, J.2
Wang, J.3
-
38
-
-
50249167673
-
Age-dependent epigenetic control of differentiation inhibitors is critical for remyelination efficiency
-
Shen S, Sandoval J, Swiss VA, et al. Age-dependent epigenetic control of differentiation inhibitors is critical for remyelination efficiency. Nat Neurosci 2008, 11:1024-1034.
-
(2008)
Nat Neurosci
, vol.11
, pp. 1024-1034
-
-
Shen, S.1
Sandoval, J.2
Swiss, V.A.3
-
39
-
-
58149233779
-
Identification of dynamically regulated microRNA and mRNA networks in developing oligodendrocytes
-
Lau P, Verrier JD, Nielsen JA, Johnson KR, Notterpek L, Hudson LD Identification of dynamically regulated microRNA and mRNA networks in developing oligodendrocytes. J Neurosci 2008, 28:11720-11730.
-
(2008)
J Neurosci
, vol.28
, pp. 11720-11730
-
-
Lau, P.1
Verrier, J.D.2
Nielsen, J.A.3
Johnson, K.R.4
Notterpek, L.5
Hudson, L.D.6
-
40
-
-
77649175470
-
Dicer1 and miR-219 are required for normal oligodendrocyte differentiation and myelination
-
Dugas JC, Cuellar TL, Scholze A, et al. Dicer1 and miR-219 are required for normal oligodendrocyte differentiation and myelination. Neuron 2010, 65:597-611.
-
(2010)
Neuron
, vol.65
, pp. 597-611
-
-
Dugas, J.C.1
Cuellar, T.L.2
Scholze, A.3
-
41
-
-
77649166937
-
MicroRNA-mediated control of oligodendrocyte differentiation
-
Zhao X, He X, Han X, et al. MicroRNA-mediated control of oligodendrocyte differentiation. Neuron 2010, 65:612-626.
-
(2010)
Neuron
, vol.65
, pp. 612-626
-
-
Zhao, X.1
He, X.2
Han, X.3
-
42
-
-
0033753779
-
The DNA methyltransferases of mammals
-
Bestor TH The DNA methyltransferases of mammals. Hum Mol Genet 2000, 9:2395-2402.
-
(2000)
Hum Mol Genet
, vol.9
, pp. 2395-2402
-
-
Bestor, T.H.1
-
43
-
-
0028267714
-
Expression of DNA methyltransferase gene in mature and immature neurons as well as proliferating cells in mice
-
Goto K, Numata M, Komura JI, Ono T, Bestor TH, Kondo H Expression of DNA methyltransferase gene in mature and immature neurons as well as proliferating cells in mice. Differentiation 1994, 56:39-44.
-
(1994)
Differentiation
, vol.56
, pp. 39-44
-
-
Goto, K.1
Numata, M.2
Komura, J.I.3
Ono, T.4
Bestor, T.H.5
Kondo, H.6
-
44
-
-
16444381345
-
Dynamic expression of de novo DNA methyltransferases Dnmt3a and Dnmt3b in the central nervous system
-
Feng J, Chang H, Li E, Fan G Dynamic expression of de novo DNA methyltransferases Dnmt3a and Dnmt3b in the central nervous system. J Neurosci Res 2005, 79:734-746.
-
(2005)
J Neurosci Res
, vol.79
, pp. 734-746
-
-
Feng, J.1
Chang, H.2
Li, E.3
Fan, G.4
-
45
-
-
0024081657
-
Cytosine methylation prevents binding to DNA of a HeLa cell transcription factor required for optimal expression of the adenovirus major late promoter
-
Watt F, Molloy PL Cytosine methylation prevents binding to DNA of a HeLa cell transcription factor required for optimal expression of the adenovirus major late promoter. Genes Dev 1988, 2:1136-1143.
-
(1988)
Genes Dev
, vol.2
, pp. 1136-1143
-
-
Watt, F.1
Molloy, P.L.2
-
46
-
-
0035656305
-
DNA methylation is a critical cell-intrinsic determinant of astrocyte differentiation in the fetal brain
-
Takizawa T, Nakashima K, Namihira M, et al. DNA methylation is a critical cell-intrinsic determinant of astrocyte differentiation in the fetal brain. Dev Cell 2001, 1:749-758.
-
(2001)
Dev Cell
, vol.1
, pp. 749-758
-
-
Takizawa, T.1
Nakashima, K.2
Namihira, M.3
-
47
-
-
7544231794
-
Intragenic DNA methylation alters chromatin structure and elongation efficiency in mammalian cells
-
Lorincz MC, Dickerson DR, Schmitt M, Groudine M Intragenic DNA methylation alters chromatin structure and elongation efficiency in mammalian cells. Nat Struct Mol Biol 2004, 11:1068-1075.
-
(2004)
Nat Struct Mol Biol
, vol.11
, pp. 1068-1075
-
-
Lorincz, M.C.1
Dickerson, D.R.2
Schmitt, M.3
Groudine, M.4
-
48
-
-
80455176999
-
CTCF-promoted RNA polymerase II pausing links DNA methylation to splicing
-
Shukla S, Kavak E, Gregory M, et al. CTCF-promoted RNA polymerase II pausing links DNA methylation to splicing. Nature 2011, 479:74-79.
-
(2011)
Nature
, vol.479
, pp. 74-79
-
-
Shukla, S.1
Kavak, E.2
Gregory, M.3
-
49
-
-
79960979256
-
Allele-specific transcriptional elongation regulates monoallelic expression of the IGF2BP1 gene
-
Thomas BJ, Rubio ED, Krumm N, et al. Allele-specific transcriptional elongation regulates monoallelic expression of the IGF2BP1 gene. Epigenetics Chromatin 2011, 4:14.
-
(2011)
Epigenetics Chromatin
, vol.4
, pp. 14
-
-
Thomas, B.J.1
Rubio, E.D.2
Krumm, N.3
-
50
-
-
5444238192
-
DNA demethylation is necessary for the epigenetic reprogramming of somatic cell nuclei
-
Simonsson S, Gurdon J DNA demethylation is necessary for the epigenetic reprogramming of somatic cell nuclei. Nat Cell Biol 2004, 6:984-990.
-
(2004)
Nat Cell Biol
, vol.6
, pp. 984-990
-
-
Simonsson, S.1
Gurdon, J.2
-
51
-
-
0034598784
-
Demethylation of the zygotic paternal genome
-
Mayer W, Niveleau A, Walter J, Fundele R, Haaf T Demethylation of the zygotic paternal genome. Nature 2000, 403:501-502.
-
(2000)
Nature
, vol.403
, pp. 501-502
-
-
Mayer, W.1
Niveleau, A.2
Walter, J.3
Fundele, R.4
Haaf, T.5
-
52
-
-
0034176639
-
Active demethylation of the paternal genome in the mouse zygote
-
Oswald J, Engemann S, Lane N, et al. Active demethylation of the paternal genome in the mouse zygote. Curr Biol 2000, 10:475-478.
-
(2000)
Curr Biol
, vol.10
, pp. 475-478
-
-
Oswald, J.1
Engemann, S.2
Lane, N.3
-
53
-
-
0036768615
-
Epigenetic reprogramming in mouse primordial germ cells
-
Hajkova P, Erhardt S, Lane N, et al. Epigenetic reprogramming in mouse primordial germ cells. Mech Dev 2002, 117:15-23.
-
(2002)
Mech Dev
, vol.117
, pp. 15-23
-
-
Hajkova, P.1
Erhardt, S.2
Lane, N.3
-
54
-
-
0036333598
-
Erasing genomic imprinting memory in mouse clone embryos produced from day 11.5 primordial germ cells
-
Lee J, Inoue K, Ono R, et al. Erasing genomic imprinting memory in mouse clone embryos produced from day 11.5 primordial germ cells. Development 2002, 129:1807-1817.
-
(2002)
Development
, vol.129
, pp. 1807-1817
-
-
Lee, J.1
Inoue, K.2
Ono, R.3
-
55
-
-
0033575886
-
The thymine glycosylase MBD4 can bind to the product of deamination at methylated CpG sites
-
Hendrich B, Hardeland U, Ng HH, Jiricny J, Bird A The thymine glycosylase MBD4 can bind to the product of deamination at methylated CpG sites. Nature 1999, 401:301-304.
-
(1999)
Nature
, vol.401
, pp. 301-304
-
-
Hendrich, B.1
Hardeland, U.2
Ng, H.H.3
Jiricny, J.4
Bird, A.5
-
56
-
-
73349104113
-
Active DNA demethylation mediated by DNA glycosylases
-
Zhu JK Active DNA demethylation mediated by DNA glycosylases. Annu Rev Genet 2009, 43:143-166.
-
(2009)
Annu Rev Genet
, vol.43
, pp. 143-166
-
-
Zhu, J.K.1
-
57
-
-
83855163995
-
Uncovering the role of 5-hydroxymethylcytosine in the epigenome
-
Branco MR, Ficz G, Reik W Uncovering the role of 5-hydroxymethylcytosine in the epigenome. Nat Rev Genet 2011, 13:7-13.
-
(2011)
Nat Rev Genet
, vol.13
, pp. 7-13
-
-
Branco, M.R.1
Ficz, G.2
Reik, W.3
-
58
-
-
82955207588
-
Mechanisms and functions of Tet protein-mediated 5-methylcytosine oxidation
-
Wu H, Zhang Y Mechanisms and functions of Tet protein-mediated 5-methylcytosine oxidation. Genes Dev 2011, 25:2436-2452.
-
(2011)
Genes Dev
, vol.25
, pp. 2436-2452
-
-
Wu, H.1
Zhang, Y.2
-
59
-
-
10644282845
-
Activation-induced cytidine deaminase deaminates 5-methylcytosine in DNA and is expressed in pluripotent tissues: implications for epigenetic reprogramming
-
Morgan HD, Dean W, Coker HA, Reik W, Petersen-Mahrt SK Activation-induced cytidine deaminase deaminates 5-methylcytosine in DNA and is expressed in pluripotent tissues: implications for epigenetic reprogramming. J Biol Chem 2004, 279:52353-52360.
-
(2004)
J Biol Chem
, vol.279
, pp. 52353-52360
-
-
Morgan, H.D.1
Dean, W.2
Coker, H.A.3
Reik, W.4
Petersen-Mahrt, S.K.5
-
60
-
-
77249148019
-
Genome-wide erasure of DNA methylation in mouse primordial germ cells is affected by AID deficiency
-
Popp C, Dean W, Feng S, et al. Genome-wide erasure of DNA methylation in mouse primordial germ cells is affected by AID deficiency. Nature 2010, 463:1101-1105.
-
(2010)
Nature
, vol.463
, pp. 1101-1105
-
-
Popp, C.1
Dean, W.2
Feng, S.3
-
61
-
-
82855176833
-
Epigenetic reprogramming in mouse pre-implantation development and primordial germ cells
-
Saitou M, Kagiwada S, Kurimoto K Epigenetic reprogramming in mouse pre-implantation development and primordial germ cells. Development 2012, 139:15-31.
-
(2012)
Development
, vol.139
, pp. 15-31
-
-
Saitou, M.1
Kagiwada, S.2
Kurimoto, K.3
-
62
-
-
1842411320
-
Crystal structure of the nucleosome core particle at 2.8 A resolution
-
Luger K, Mader AW, Richmond RK, Sargent DF, Richmond TJ Crystal structure of the nucleosome core particle at 2.8 A resolution. Nature 1997, 389:251-260.
-
(1997)
Nature
, vol.389
, pp. 251-260
-
-
Luger, K.1
Mader, A.W.2
Richmond, R.K.3
Sargent, D.F.4
Richmond, T.J.5
-
63
-
-
33847106524
-
Higher-order structures of chromatin: the elusive 30 nm fiber
-
Tremethick DJ Higher-order structures of chromatin: the elusive 30 nm fiber. Cell 2007, 128:651-654.
-
(2007)
Cell
, vol.128
, pp. 651-654
-
-
Tremethick, D.J.1
-
64
-
-
2942746179
-
Histone variants, nucleosome assembly and epigenetic inheritance
-
Henikoff S, Furuyama T, Ahmad K Histone variants, nucleosome assembly and epigenetic inheritance. Trends Genet 2004, 20:306-320.
-
(2004)
Trends Genet
, vol.20
, pp. 306-320
-
-
Henikoff, S.1
Furuyama, T.2
Ahmad, K.3
-
65
-
-
84862732690
-
New insights into nucleosome and chromatin structure: an ordered state or a disordered affair?
-
Luger K, Dechassa ML, Tremethick DJ New insights into nucleosome and chromatin structure: an ordered state or a disordered affair?. Nat Rev Mol Cell Biol 2012, 13:436-447.
-
(2012)
Nat Rev Mol Cell Biol
, vol.13
, pp. 436-447
-
-
Luger, K.1
Dechassa, M.L.2
Tremethick, D.J.3
-
66
-
-
55549141877
-
Histone H2A.Z and DNA methylation are mutually antagonistic chromatin marks
-
Zilberman D, Coleman-Derr D, Ballinger T, Henikoff S Histone H2A.Z and DNA methylation are mutually antagonistic chromatin marks. Nature 2008, 456:125-129.
-
(2008)
Nature
, vol.456
, pp. 125-129
-
-
Zilberman, D.1
Coleman-Derr, D.2
Ballinger, T.3
Henikoff, S.4
-
67
-
-
78650816688
-
The histone variant macroH2A suppresses melanoma progression through regulation of CDK8
-
Kapoor A, Goldberg MS, Cumberland LK, et al. The histone variant macroH2A suppresses melanoma progression through regulation of CDK8. Nature 2010, 468:1105-1109.
-
(2010)
Nature
, vol.468
, pp. 1105-1109
-
-
Kapoor, A.1
Goldberg, M.S.2
Cumberland, L.K.3
-
68
-
-
79958815889
-
Histone variant macroH2A confers resistance to nuclear reprogramming
-
Pasque V, Gillich A, Garrett N, Gurdon JB Histone variant macroH2A confers resistance to nuclear reprogramming. EMBO J 2011, 30:2373-2387.
-
(2011)
EMBO J
, vol.30
, pp. 2373-2387
-
-
Pasque, V.1
Gillich, A.2
Garrett, N.3
Gurdon, J.B.4
-
69
-
-
77951222534
-
H2A.Bbd: an X-chromosome-encoded histone involved in mammalian spermiogenesis
-
Ishibashi T, Li A, Eirin-Lopez JM, et al. H2A.Bbd: an X-chromosome-encoded histone involved in mammalian spermiogenesis. Nucleic Acids Res 2010, 38:1780-1789.
-
(2010)
Nucleic Acids Res
, vol.38
, pp. 1780-1789
-
-
Ishibashi, T.1
Li, A.2
Eirin-Lopez, J.M.3
-
70
-
-
84855457949
-
A unique H2A histone variant occupies the transcriptional start site of active genes
-
Soboleva TA, Nekrasov M, Pahwa A, Williams R, Huttley GA, Tremethick DJ A unique H2A histone variant occupies the transcriptional start site of active genes. Nat Struct Mol Biol 2011, 19:25-30.
-
(2011)
Nat Struct Mol Biol
, vol.19
, pp. 25-30
-
-
Soboleva, T.A.1
Nekrasov, M.2
Pahwa, A.3
Williams, R.4
Huttley, G.A.5
Tremethick, D.J.6
-
71
-
-
67650725820
-
The biology of chromatin remodeling complexes
-
Clapier CR, Cairns BR The biology of chromatin remodeling complexes. Annu Rev Biochem 2009, 78:273-304.
-
(2009)
Annu Rev Biochem
, vol.78
, pp. 273-304
-
-
Clapier, C.R.1
Cairns, B.R.2
-
72
-
-
79952539053
-
ATP-dependent chromatin remodeling: genetics, genomics and mechanisms
-
Hargreaves DC, Crabtree GR ATP-dependent chromatin remodeling: genetics, genomics and mechanisms. Cell Res 2011, 21:396-420.
-
(2011)
Cell Res
, vol.21
, pp. 396-420
-
-
Hargreaves, D.C.1
Crabtree, G.R.2
-
73
-
-
0031244521
-
Nuclear histone acetylases and deacetylases and transcriptional regulation: HATs off to HDACs
-
Hassig CA, Schreiber SL Nuclear histone acetylases and deacetylases and transcriptional regulation: HATs off to HDACs. Curr Opin Chem Biol 1997, 1:300-308.
-
(1997)
Curr Opin Chem Biol
, vol.1
, pp. 300-308
-
-
Hassig, C.A.1
Schreiber, S.L.2
-
74
-
-
34249083199
-
Sirtuins in mammals: insights into their biological function
-
Michan S, Sinclair D Sirtuins in mammals: insights into their biological function. Biochem J 2007, 404:1-13.
-
(2007)
Biochem J
, vol.404
, pp. 1-13
-
-
Michan, S.1
Sinclair, D.2
-
75
-
-
79951686964
-
The sirtuin pathway in ageing and Alzheimer disease: mechanistic and therapeutic considerations
-
Bonda DJ, Lee HG, Camins A, et al. The sirtuin pathway in ageing and Alzheimer disease: mechanistic and therapeutic considerations. Lancet Neurol 2011, 10:275-279.
-
(2011)
Lancet Neurol
, vol.10
, pp. 275-279
-
-
Bonda, D.J.1
Lee, H.G.2
Camins, A.3
-
76
-
-
22344446199
-
Histone modifications affect timing of oligodendrocyte progenitor differentiation in the developing rat brain
-
Shen S, Li J, Casaccia-Bonnefil P Histone modifications affect timing of oligodendrocyte progenitor differentiation in the developing rat brain. J Cell Biol 2005, 169:577-589.
-
(2005)
J Cell Biol
, vol.169
, pp. 577-589
-
-
Shen, S.1
Li, J.2
Casaccia-Bonnefil, P.3
-
77
-
-
4644261125
-
Regulation of histone acetylation during memory formation in the hippocampus
-
Levenson JM, O'Riordan KJ, Brown KD, Trinh MA, Molfese DL, Sweatt JD Regulation of histone acetylation during memory formation in the hippocampus. J Biol Chem 2004, 279:40545-40559.
-
(2004)
J Biol Chem
, vol.279
, pp. 40545-40559
-
-
Levenson, J.M.1
O'Riordan, K.J.2
Brown, K.D.3
Trinh, M.A.4
Molfese, D.L.5
Sweatt, J.D.6
-
78
-
-
77952168294
-
Altered histone acetylation is associated with age-dependent memory impairment in mice
-
Peleg S, Sananbenesi F, Zovoilis A, et al. Altered histone acetylation is associated with age-dependent memory impairment in mice. Science 2010, 328:753-756.
-
(2010)
Science
, vol.328
, pp. 753-756
-
-
Peleg, S.1
Sananbenesi, F.2
Zovoilis, A.3
-
79
-
-
34547624303
-
Genome-wide maps of chromatin state in pluripotent and lineage-committed cells
-
Mikkelsen TS, Ku M, Jaffe DB, et al. Genome-wide maps of chromatin state in pluripotent and lineage-committed cells. Nature 2007, 448:553-560.
-
(2007)
Nature
, vol.448
, pp. 553-560
-
-
Mikkelsen, T.S.1
Ku, M.2
Jaffe, D.B.3
-
80
-
-
5044228483
-
Human PAD4 regulates histone arginine methylation levels via demethylimination
-
Wang Y, Wysocka J, Sayegh J, et al. Human PAD4 regulates histone arginine methylation levels via demethylimination. Science 2004, 306:279-283.
-
(2004)
Science
, vol.306
, pp. 279-283
-
-
Wang, Y.1
Wysocka, J.2
Sayegh, J.3
-
81
-
-
70249133329
-
Functional connection between deimination and deacetylation of histones
-
Denis H, Deplus R, Putmans P, Yamada M, Metivier R, Fuks F Functional connection between deimination and deacetylation of histones. Mol Cell Biol 2009, 29:4982-4993.
-
(2009)
Mol Cell Biol
, vol.29
, pp. 4982-4993
-
-
Denis, H.1
Deplus, R.2
Putmans, P.3
Yamada, M.4
Metivier, R.5
Fuks, F.6
-
82
-
-
0034523266
-
SUMO-nonclassical ubiquitin
-
Melchior F SUMO-nonclassical ubiquitin. Annu Rev Cell Dev Biol 2000, 16:591-626.
-
(2000)
Annu Rev Cell Dev Biol
, vol.16
, pp. 591-626
-
-
Melchior, F.1
-
85
-
-
40849106789
-
Histone ubiquitination: triggering gene activity
-
Weake VM, Workman JL Histone ubiquitination: triggering gene activity. Mol Cell 2008, 29:653-663.
-
(2008)
Mol Cell
, vol.29
, pp. 653-663
-
-
Weake, V.M.1
Workman, J.L.2
-
86
-
-
84865790047
-
An integrated encyclopedia of DNA elements in the human genome
-
Bernstein BE, Birney E, Dunham I, Green ED, Gunter C, Snyder M An integrated encyclopedia of DNA elements in the human genome. Nature 2012, 489:57-74.
-
(2012)
Nature
, vol.489
, pp. 57-74
-
-
Bernstein, B.E.1
Birney, E.2
Dunham, I.3
Green, E.D.4
Gunter, C.5
Snyder, M.6
-
87
-
-
84864126183
-
Emerging roles of non-coding RNAs in brain evolution, development, plasticity and disease
-
Qureshi IA, Mehler MF Emerging roles of non-coding RNAs in brain evolution, development, plasticity and disease. Nat Rev Neurosci 2012, 13:528-541.
-
(2012)
Nat Rev Neurosci
, vol.13
, pp. 528-541
-
-
Qureshi, I.A.1
Mehler, M.F.2
-
88
-
-
81355142141
-
Non-coding RNAs in human disease
-
Esteller M Non-coding RNAs in human disease. Nat Rev Genet 2011, 12:861-874.
-
(2011)
Nat Rev Genet
, vol.12
, pp. 861-874
-
-
Esteller, M.1
-
89
-
-
84865727393
-
The GENCODE v7 catalog of human long noncoding RNAs: analysis of their gene structure, evolution, and expression
-
Derrien T, Johnson R, Bussotti G, et al. The GENCODE v7 catalog of human long noncoding RNAs: analysis of their gene structure, evolution, and expression. Genome Res 2012, 22:1775-1789.
-
(2012)
Genome Res
, vol.22
, pp. 1775-1789
-
-
Derrien, T.1
Johnson, R.2
Bussotti, G.3
-
90
-
-
84871262247
-
Non-coding RNAs in neural networks, REST-assured
-
Rossbach M Non-coding RNAs in neural networks, REST-assured. Front Genet 2011, 2:8.
-
(2011)
Front Genet
, vol.2
, pp. 8
-
-
Rossbach, M.1
-
91
-
-
67650921949
-
Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression
-
Khalil AM, Guttman M, Huarte M, et al. Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression. Proc Natl Acad Sci USA 2009, 106:11667-11672.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 11667-11672
-
-
Khalil, A.M.1
Guttman, M.2
Huarte, M.3
-
92
-
-
77954572735
-
Long noncoding RNA as modular scaffold of histone modification complexes
-
Tsai MC, Manor O, Wan Y, et al. Long noncoding RNA as modular scaffold of histone modification complexes. Science 2010, 329:689-693.
-
(2010)
Science
, vol.329
, pp. 689-693
-
-
Tsai, M.C.1
Manor, O.2
Wan, Y.3
-
93
-
-
8144225486
-
MicroRNA genes are transcribed by RNA polymerase II
-
Lee Y, Kim M, Han J, et al. MicroRNA genes are transcribed by RNA polymerase II. EMBO J 2004, 23:4051-4060.
-
(2004)
EMBO J
, vol.23
, pp. 4051-4060
-
-
Lee, Y.1
Kim, M.2
Han, J.3
-
94
-
-
0141843656
-
The nuclear RNase III Drosha initiates microRNA processing
-
Lee Y, Ahn C, Han J, et al. The nuclear RNase III Drosha initiates microRNA processing. Nature 2003, 425:415-419.
-
(2003)
Nature
, vol.425
, pp. 415-419
-
-
Lee, Y.1
Ahn, C.2
Han, J.3
-
95
-
-
0347361541
-
Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs
-
Yi R, Qin Y, Macara IG, Cullen BR Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs. Genes Dev 2003, 17:3011-3016.
-
(2003)
Genes Dev
, vol.17
, pp. 3011-3016
-
-
Yi, R.1
Qin, Y.2
Macara, I.G.3
Cullen, B.R.4
-
96
-
-
78751477191
-
Gene silencing by microRNAs: contributions of translational repression and mRNA decay
-
Huntzinger E, Izaurralde E Gene silencing by microRNAs: contributions of translational repression and mRNA decay. Nat Rev Genet 2011, 12:99-110.
-
(2011)
Nat Rev Genet
, vol.12
, pp. 99-110
-
-
Huntzinger, E.1
Izaurralde, E.2
-
97
-
-
13944282215
-
Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs
-
Lim LP, Lau NC, Garrett-Engele P, et al. Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs. Nature 2005, 433:769-773.
-
(2005)
Nature
, vol.433
, pp. 769-773
-
-
Lim, L.P.1
Lau, N.C.2
Garrett-Engele, P.3
-
98
-
-
79957608247
-
Revealing the genetic basis of multiple sclerosis: are we there yet?
-
Baranzini SE Revealing the genetic basis of multiple sclerosis: are we there yet?. Curr Opin Genet Dev 2011, 21:317-324.
-
(2011)
Curr Opin Genet Dev
, vol.21
, pp. 317-324
-
-
Baranzini, S.E.1
-
99
-
-
38949107656
-
Environmental factors and multiple sclerosis
-
Ebers GC Environmental factors and multiple sclerosis. Lancet Neurol 2008, 7:268-277.
-
(2008)
Lancet Neurol
, vol.7
, pp. 268-277
-
-
Ebers, G.C.1
-
100
-
-
77949424680
-
Environmental factors and their timing in adult-onset multiple sclerosis
-
Handel AE, Giovannoni G, Ebers GC, Ramagopalan SV Environmental factors and their timing in adult-onset multiple sclerosis. Nat Rev Neurol 2010, 6:156-166.
-
(2010)
Nat Rev Neurol
, vol.6
, pp. 156-166
-
-
Handel, A.E.1
Giovannoni, G.2
Ebers, G.C.3
Ramagopalan, S.V.4
-
101
-
-
0001882253
-
Multiple sclerosis: from the standpoint of geographic distribution and race
-
Davenport CB Multiple sclerosis: from the standpoint of geographic distribution and race. Arch Neur Psych 1922, 8:51-58.
-
(1922)
Arch Neur Psych
, vol.8
, pp. 51-58
-
-
Davenport, C.B.1
-
102
-
-
0000241517
-
Some comments on the relationship of the distribution of multiple sclerosis to latitude, solar radiation, and other variables
-
Acheson ED, Bachrach CA, Wright FM Some comments on the relationship of the distribution of multiple sclerosis to latitude, solar radiation, and other variables. Acta Psychiatr Scand Suppl 1960, 35:132-147.
-
(1960)
Acta Psychiatr Scand Suppl
, vol.35
, pp. 132-147
-
-
Acheson, E.D.1
Bachrach, C.A.2
Wright, F.M.3
-
103
-
-
0003006753
-
The geography of multiple sclerosis reflects genetic susceptibility
-
Bulman DE, Ebers GC The geography of multiple sclerosis reflects genetic susceptibility. J Trop Geogr Neurol 1992, 2:66-72.
-
(1992)
J Trop Geogr Neurol
, vol.2
, pp. 66-72
-
-
Bulman, D.E.1
Ebers, G.C.2
-
104
-
-
0013950284
-
Risk of multiple sclerosis related to age at immigration to Israel
-
Alter M, Leibowitz U, Speer J Risk of multiple sclerosis related to age at immigration to Israel. Arch Neurol 1966, 15:234-237.
-
(1966)
Arch Neurol
, vol.15
, pp. 234-237
-
-
Alter, M.1
Leibowitz, U.2
Speer, J.3
-
105
-
-
0030670811
-
Age at immigration to England of Asian and Caribbean immigrants and the risk of developing multiple sclerosis
-
Dean G, Elian M Age at immigration to England of Asian and Caribbean immigrants and the risk of developing multiple sclerosis. J Neurol Neurosurg Psychiatry 1997, 63:565-568.
-
(1997)
J Neurol Neurosurg Psychiatry
, vol.63
, pp. 565-568
-
-
Dean, G.1
Elian, M.2
-
106
-
-
0025195157
-
Effect of low saturated fat diet in early and late cases of multiple sclerosis
-
Swank RL, Dugan BB Effect of low saturated fat diet in early and late cases of multiple sclerosis. Lancet 1990, 336:37-39.
-
(1990)
Lancet
, vol.336
, pp. 37-39
-
-
Swank, R.L.1
Dugan, B.B.2
-
107
-
-
0030808055
-
Ecologic studies of multiple sclerosis
-
Lauer K Ecologic studies of multiple sclerosis. Neurology 1997, 49(suppl 2):18-26.
-
(1997)
Neurology
, vol.49
, Issue.SUPPL. 2
, pp. 18-26
-
-
Lauer, K.1
-
108
-
-
0347364679
-
Antibody cross-reactivity between myelin oligodendrocyte glycoprotein and the milk protein butyrophilin in multiple sclerosis
-
Guggenmos J, Schubart AS, Ogg S, et al. Antibody cross-reactivity between myelin oligodendrocyte glycoprotein and the milk protein butyrophilin in multiple sclerosis. J Immunol 2004, 172:661-668.
-
(2004)
J Immunol
, vol.172
, pp. 661-668
-
-
Guggenmos, J.1
Schubart, A.S.2
Ogg, S.3
-
109
-
-
34347264890
-
Regional variations in the prevalence of multiple sclerosis in French farmers
-
Vukusic S, Van Bockstael V, Gosselin S, Confavreux C Regional variations in the prevalence of multiple sclerosis in French farmers. J Neurol Neurosurg Psychiatry 2007, 78:707-709.
-
(2007)
J Neurol Neurosurg Psychiatry
, vol.78
, pp. 707-709
-
-
Vukusic, S.1
Van Bockstael, V.2
Gosselin, S.3
Confavreux, C.4
-
110
-
-
33845720114
-
Serum 25-hydroxyvitamin D levels and risk of multiple sclerosis
-
Munger KL, Levin LI, Hollis BW, Howard NS, Ascherio A Serum 25-hydroxyvitamin D levels and risk of multiple sclerosis. JAMA 2006, 296:2832-2838.
-
(2006)
JAMA
, vol.296
, pp. 2832-2838
-
-
Munger, K.L.1
Levin, L.I.2
Hollis, B.W.3
Howard, N.S.4
Ascherio, A.5
-
111
-
-
0345830740
-
Vitamin D intake and incidence of multiple sclerosis
-
Munger KL, Zhang SM, O'Reilly E, et al. Vitamin D intake and incidence of multiple sclerosis. Neurology 2004, 62:60-65.
-
(2004)
Neurology
, vol.62
, pp. 60-65
-
-
Munger, K.L.1
Zhang, S.M.2
O'Reilly, E.3
-
112
-
-
12344314461
-
Timing of birth and risk of multiple sclerosis: population based study
-
Willer CJ, Dyment DA, Sadovnick AD, Rothwell PM, Murray TJ, Ebers GC Timing of birth and risk of multiple sclerosis: population based study. BMJ 2005, 330:120.
-
(2005)
BMJ
, vol.330
, pp. 120
-
-
Willer, C.J.1
Dyment, D.A.2
Sadovnick, A.D.3
Rothwell, P.M.4
Murray, T.J.5
Ebers, G.C.6
-
113
-
-
72149120030
-
Timing of birth and risk of multiple sclerosis in the Scottish population
-
Bayes HK, Weir CJ, O'Leary C Timing of birth and risk of multiple sclerosis in the Scottish population. Eur Neurol 2010, 63:36-40.
-
(2010)
Eur Neurol
, vol.63
, pp. 36-40
-
-
Bayes, H.K.1
Weir, C.J.2
O'Leary, C.3
-
114
-
-
77956885532
-
A ChIP-seq defined genome-wide map of vitamin D receptor binding: associations with disease and evolution
-
Ramagopalan SV, Heger A, Berlanga AJ, et al. A ChIP-seq defined genome-wide map of vitamin D receptor binding: associations with disease and evolution. Genome Res 2010, 20:1352-1360.
-
(2010)
Genome Res
, vol.20
, pp. 1352-1360
-
-
Ramagopalan, S.V.1
Heger, A.2
Berlanga, A.J.3
-
115
-
-
65349184462
-
Folic acid, methylation and neural tube closure in humans
-
Blom HJ Folic acid, methylation and neural tube closure in humans. Birth Defects Res A Clin Mol Teratol 2009, 85:295-302.
-
(2009)
Birth Defects Res A Clin Mol Teratol
, vol.85
, pp. 295-302
-
-
Blom, H.J.1
-
116
-
-
78650446334
-
Paternally induced transgenerational environmental reprogramming of metabolic gene expression in mammals
-
Carone BR, Fauquier L, Habib N, et al. Paternally induced transgenerational environmental reprogramming of metabolic gene expression in mammals. Cell 2010, 143:1084-1096.
-
(2010)
Cell
, vol.143
, pp. 1084-1096
-
-
Carone, B.R.1
Fauquier, L.2
Habib, N.3
-
117
-
-
50049108528
-
Feeding pregnant rats a protein-restricted diet persistently alters the methylation of specific cytosines in the hepatic PPAR alpha promoter of the offspring
-
Lillycrop KA, Phillips ES, Torrens C, Hanson MA, Jackson AA, Burdge GC Feeding pregnant rats a protein-restricted diet persistently alters the methylation of specific cytosines in the hepatic PPAR alpha promoter of the offspring. Br J Nutr 2008, 100:278-282.
-
(2008)
Br J Nutr
, vol.100
, pp. 278-282
-
-
Lillycrop, K.A.1
Phillips, E.S.2
Torrens, C.3
Hanson, M.A.4
Jackson, A.A.5
Burdge, G.C.6
-
118
-
-
72049092916
-
Body size and risk of MS in two cohorts of US women
-
Munger KL, Chitnis T, Ascherio A Body size and risk of MS in two cohorts of US women. Neurology 2009, 73:1543-1550.
-
(2009)
Neurology
, vol.73
, pp. 1543-1550
-
-
Munger, K.L.1
Chitnis, T.2
Ascherio, A.3
-
119
-
-
0031731258
-
Nutritional factors in the aetiology of multiple sclerosis: a case-control study in Montreal, Canada
-
Ghadirian P, Jain M, Ducic S, Shatenstein B, Morisset R Nutritional factors in the aetiology of multiple sclerosis: a case-control study in Montreal, Canada. Int J Epidemiol 1998, 27:845-852.
-
(1998)
Int J Epidemiol
, vol.27
, pp. 845-852
-
-
Ghadirian, P.1
Jain, M.2
Ducic, S.3
Shatenstein, B.4
Morisset, R.5
-
120
-
-
79952748674
-
Proinflammatory T-cell responses to gut microbiota promote experimental autoimmune encephalomyelitis
-
Lee YK, Menezes JS, Umesaki Y, Mazmanian SK Proinflammatory T-cell responses to gut microbiota promote experimental autoimmune encephalomyelitis. Proc Natl Acad Sci USA 2011, 108(suppl 1):4615-4622.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, Issue.SUPPL. 1
, pp. 4615-4622
-
-
Lee, Y.K.1
Menezes, J.S.2
Umesaki, Y.3
Mazmanian, S.K.4
-
121
-
-
81855167104
-
Commensal microbiota and myelin autoantigen cooperate to trigger autoimmune demyelination
-
Berer K, Mues M, Koutrolos M, et al. Commensal microbiota and myelin autoantigen cooperate to trigger autoimmune demyelination. Nature 2011, 479:538-541.
-
(2011)
Nature
, vol.479
, pp. 538-541
-
-
Berer, K.1
Mues, M.2
Koutrolos, M.3
-
122
-
-
84867845255
-
The interplay between the intestinal microbiota and the brain
-
Collins SM, Surette M, Bercik P The interplay between the intestinal microbiota and the brain. Nat Rev Microbiol 2012, 10:735-742.
-
(2012)
Nat Rev Microbiol
, vol.10
, pp. 735-742
-
-
Collins, S.M.1
Surette, M.2
Bercik, P.3
-
123
-
-
84859389254
-
The microbiome in infectious disease and inflammation
-
Honda K, Littman DR The microbiome in infectious disease and inflammation. Annu Rev Immunol 2012, 30:759-795.
-
(2012)
Annu Rev Immunol
, vol.30
, pp. 759-795
-
-
Honda, K.1
Littman, D.R.2
-
124
-
-
77951836633
-
Genome, epigenome and RNA sequences of monozygotic twins discordant for multiple sclerosis
-
Baranzini SE, Mudge J, van Velkinburgh JC, et al. Genome, epigenome and RNA sequences of monozygotic twins discordant for multiple sclerosis. Nature 2010, 464:1351-1356.
-
(2010)
Nature
, vol.464
, pp. 1351-1356
-
-
Baranzini, S.E.1
Mudge, J.2
van Velkinburgh, J.C.3
-
125
-
-
1042278765
-
The history of cancer epigenetics
-
Feinberg AP, Tycko B The history of cancer epigenetics. Nat Rev Cancer 2004, 4:143-153.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 143-153
-
-
Feinberg, A.P.1
Tycko, B.2
-
126
-
-
74849112968
-
Methylation patterns of cell-free plasma DNA in relapsing-remitting multiple sclerosis
-
Liggett T, Melnikov A, Tilwalli S, et al. Methylation patterns of cell-free plasma DNA in relapsing-remitting multiple sclerosis. J Neurol Sci 2010, 290:16-21.
-
(2010)
J Neurol Sci
, vol.290
, pp. 16-21
-
-
Liggett, T.1
Melnikov, A.2
Tilwalli, S.3
-
127
-
-
67349273027
-
MicroRNA in autoimmunity and autoimmune diseases
-
Pauley KM, Cha S, Chan EK MicroRNA in autoimmunity and autoimmune diseases. J Autoimmun 2009, 32:189-194.
-
(2009)
J Autoimmun
, vol.32
, pp. 189-194
-
-
Pauley, K.M.1
Cha, S.2
Chan, E.K.3
-
128
-
-
70449716915
-
MicroRNA miR-326 regulates TH-17 differentiation and is associated with the pathogenesis of multiple sclerosis
-
Du C, Liu C, Kang J, et al. MicroRNA miR-326 regulates TH-17 differentiation and is associated with the pathogenesis of multiple sclerosis. Nat Immunol 2009, 10:1252-1259.
-
(2009)
Nat Immunol
, vol.10
, pp. 1252-1259
-
-
Du, C.1
Liu, C.2
Kang, J.3
-
129
-
-
72649095061
-
MicroRNA profiling of multiple sclerosis lesions identifies modulators of the regulatory protein CD47
-
Junker A, Krumbholz M, Eisele S, et al. MicroRNA profiling of multiple sclerosis lesions identifies modulators of the regulatory protein CD47. Brain 2009, 132:3342-3352.
-
(2009)
Brain
, vol.132
, pp. 3342-3352
-
-
Junker, A.1
Krumbholz, M.2
Eisele, S.3
-
130
-
-
77749260581
-
Altered expression of miR-17-5p in CD4+ lymphocytes of relapsing-remitting multiple sclerosis patients
-
Lindberg RL, Hoffmann F, Mehling M, Kuhle J, Kappos L Altered expression of miR-17-5p in CD4+ lymphocytes of relapsing-remitting multiple sclerosis patients. Eur J Immunol 2010, 40:888-898.
-
(2010)
Eur J Immunol
, vol.40
, pp. 888-898
-
-
Lindberg, R.L.1
Hoffmann, F.2
Mehling, M.3
Kuhle, J.4
Kappos, L.5
-
131
-
-
77956343824
-
Altered miRNA expression in T regulatory cells in course of multiple sclerosis
-
De Santis G, Ferracin M, Biondani A, et al. Altered miRNA expression in T regulatory cells in course of multiple sclerosis. J Neuroimmunol 2010, 226:165-171.
-
(2010)
J Neuroimmunol
, vol.226
, pp. 165-171
-
-
De Santis, G.1
Ferracin, M.2
Biondani, A.3
-
132
-
-
77957888270
-
MicroRNAs miR-17 and miR-20a inhibit T cell activation genes and are under-expressed in MS whole blood
-
Cox MB, Cairns MJ, Gandhi KS, et al. MicroRNAs miR-17 and miR-20a inhibit T cell activation genes and are under-expressed in MS whole blood. PLoS One 2010, 5:12132.
-
(2010)
PLoS One
, vol.5
, pp. 12132
-
-
Cox, M.B.1
Cairns, M.J.2
Gandhi, K.S.3
-
133
-
-
80053459864
-
Expression and genetic analysis of miRNAs involved in CD4+ cell activation in patients with multiple sclerosis
-
Fenoglio C, Cantoni C, De Riz M, et al. Expression and genetic analysis of miRNAs involved in CD4+ cell activation in patients with multiple sclerosis. Neurosci Lett 2011, 504:9-12.
-
(2011)
Neurosci Lett
, vol.504
, pp. 9-12
-
-
Fenoglio, C.1
Cantoni, C.2
De Riz, M.3
-
134
-
-
84055221820
-
Genetic association and altered gene expression of mir-155 in multiple sclerosis patients
-
Paraboschi EM, Solda G, Gemmati D, et al. Genetic association and altered gene expression of mir-155 in multiple sclerosis patients. Int J Mol Sci 2011, 12:8695-8712.
-
(2011)
Int J Mol Sci
, vol.12
, pp. 8695-8712
-
-
Paraboschi, E.M.1
Solda, G.2
Gemmati, D.3
-
135
-
-
83755186512
-
Micro-RNA dysregulation in multiple sclerosis favours pro-inflammatory T-cell-mediated autoimmunity
-
Guerau-de-Arellano M, Smith KM, Godlewski J, et al. Micro-RNA dysregulation in multiple sclerosis favours pro-inflammatory T-cell-mediated autoimmunity. Brain 2011, 134:3578-3589.
-
(2011)
Brain
, vol.134
, pp. 3578-3589
-
-
Guerau-de-Arellano, M.1
Smith, K.M.2
Godlewski, J.3
-
136
-
-
84855964851
-
MicroRNA and mRNA expression profile screening in multiple sclerosis patients to unravel novel pathogenic steps and identify potential biomarkers
-
Martinelli-Boneschi F, Fenoglio C, Brambilla P, et al. MicroRNA and mRNA expression profile screening in multiple sclerosis patients to unravel novel pathogenic steps and identify potential biomarkers. Neurosci Lett 2012, 508:4-8.
-
(2012)
Neurosci Lett
, vol.508
, pp. 4-8
-
-
Martinelli-Boneschi, F.1
Fenoglio, C.2
Brambilla, P.3
-
137
-
-
67651113615
-
Differential micro RNA expression in PBMC from multiple sclerosis patients
-
Otaegui D, Baranzini SE, Armananzas R, et al. Differential micro RNA expression in PBMC from multiple sclerosis patients. PLoS One 2009, 4:6309.
-
(2009)
PLoS One
, vol.4
, pp. 6309
-
-
Otaegui, D.1
Baranzini, S.E.2
Armananzas, R.3
-
138
-
-
77149132365
-
Multiple sclerosis: microRNA expression profiles accurately differentiate patients with relapsing-remitting disease from healthy controls
-
Keller A, Leidinger P, Lange J, et al. Multiple sclerosis: microRNA expression profiles accurately differentiate patients with relapsing-remitting disease from healthy controls. PLoS One 2009, 4:7440.
-
(2009)
PLoS One
, vol.4
, pp. 7440
-
-
Keller, A.1
Leidinger, P.2
Lange, J.3
-
139
-
-
84863750004
-
Circulating microRNAs involved in multiple sclerosis
-
Siegel SR, Mackenzie J, Chaplin G, Jablonski NG, Griffiths L Circulating microRNAs involved in multiple sclerosis. Mol Biol Rep 2012, 39:6219-6225.
-
(2012)
Mol Biol Rep
, vol.39
, pp. 6219-6225
-
-
Siegel, S.R.1
Mackenzie, J.2
Chaplin, G.3
Jablonski, N.G.4
Griffiths, L.5
-
140
-
-
84871297324
-
Regulated microRNAs in the CSF of patients with multiple sclerosis: a case-control study
-
Haghikia A, Hellwig K, Baraniskin A, et al. Regulated microRNAs in the CSF of patients with multiple sclerosis: a case-control study. Neurology 2012, 79:2166-2170.
-
(2012)
Neurology
, vol.79
, pp. 2166-2170
-
-
Haghikia, A.1
Hellwig, K.2
Baraniskin, A.3
-
141
-
-
84861674736
-
Altered microRNA expression in B lymphocytes in multiple sclerosis: towards a better understanding of treatment effects
-
Sievers C, Meira M, Hoffmann F, Fontoura P, Kappos L, Lindberg RL Altered microRNA expression in B lymphocytes in multiple sclerosis: towards a better understanding of treatment effects. Clin Immunol 2012, 144:70-79.
-
(2012)
Clin Immunol
, vol.144
, pp. 70-79
-
-
Sievers, C.1
Meira, M.2
Hoffmann, F.3
Fontoura, P.4
Kappos, L.5
Lindberg, R.L.6
-
142
-
-
80053563273
-
NeurimmiRs: microRNAs in the neuroimmune interface
-
Soreq H, Wolf Y NeurimmiRs: microRNAs in the neuroimmune interface. Trends Mol Med 2011, 17:548-555.
-
(2011)
Trends Mol Med
, vol.17
, pp. 548-555
-
-
Soreq, H.1
Wolf, Y.2
-
143
-
-
80052661268
-
Silencing microRNA-155 ameliorates experimental autoimmune encephalomyelitis
-
Murugaiyan G, Beynon V, Mittal A, Joller N, Weiner HL Silencing microRNA-155 ameliorates experimental autoimmune encephalomyelitis. J Immunol 2011, 187:2213-2221.
-
(2011)
J Immunol
, vol.187
, pp. 2213-2221
-
-
Murugaiyan, G.1
Beynon, V.2
Mittal, A.3
Joller, N.4
Weiner, H.L.5
-
144
-
-
0036897351
-
Histone deacetylase activity is necessary for oligodendrocyte lineage progression
-
Marin-Husstege M, Muggironi M, Liu A, Casaccia-Bonnefil P Histone deacetylase activity is necessary for oligodendrocyte lineage progression. J Neurosci 2002, 22:10333-10345.
-
(2002)
J Neurosci
, vol.22
, pp. 10333-10345
-
-
Marin-Husstege, M.1
Muggironi, M.2
Liu, A.3
Casaccia-Bonnefil, P.4
-
145
-
-
67649797866
-
HDAC1 and HDAC2 regulate oligodendrocyte differentiation by disrupting the beta-catenin-TCF interaction
-
Ye F, Chen Y, Hoang T, et al. HDAC1 and HDAC2 regulate oligodendrocyte differentiation by disrupting the beta-catenin-TCF interaction. Nat Neurosci 2009, 12:829-838.
-
(2009)
Nat Neurosci
, vol.12
, pp. 829-838
-
-
Ye, F.1
Chen, Y.2
Hoang, T.3
-
146
-
-
79953194397
-
HDAC1 and HDAC2 control the transcriptional program of myelination and the survival of Schwann cells
-
Jacob C, Christen CN, Pereira JA, et al. HDAC1 and HDAC2 control the transcriptional program of myelination and the survival of Schwann cells. Nat Neurosci 2011, 14:429-436.
-
(2011)
Nat Neurosci
, vol.14
, pp. 429-436
-
-
Jacob, C.1
Christen, C.N.2
Pereira, J.A.3
-
147
-
-
0028342830
-
Myelin in multiple sclerosis is developmentally immature
-
Moscarello MA, Wood DD, Ackerley C, Boulias C Myelin in multiple sclerosis is developmentally immature. J Clin Invest 1994, 94:146-154.
-
(1994)
J Clin Invest
, vol.94
, pp. 146-154
-
-
Moscarello, M.A.1
Wood, D.D.2
Ackerley, C.3
Boulias, C.4
-
148
-
-
0034625091
-
Deimination of myelin basic protein. Effect of deimination of arginyl residues of myelin basic protein on its structure and susceptibility to digestion by cathepsin D
-
Pritzker LB, Joshi S, Gowan JJ, Harauz G, Moscarello MA Deimination of myelin basic protein. Effect of deimination of arginyl residues of myelin basic protein on its structure and susceptibility to digestion by cathepsin D. Biochemistry 2000, 39:5374-5381.
-
(2000)
Biochemistry
, vol.39
, pp. 5374-5381
-
-
Pritzker, L.B.1
Joshi, S.2
Gowan, J.J.3
Harauz, G.4
Moscarello, M.A.5
-
149
-
-
3042553626
-
Myelin basic protein-diverse conformational states of an intrinsically unstructured protein and its roles in myelin assembly and multiple sclerosis
-
Harauz G, Ishiyama N, Hill CM, Bates IR, Libich DS, Fares C Myelin basic protein-diverse conformational states of an intrinsically unstructured protein and its roles in myelin assembly and multiple sclerosis. Micron 2004, 35:503-542.
-
(2004)
Micron
, vol.35
, pp. 503-542
-
-
Harauz, G.1
Ishiyama, N.2
Hill, C.M.3
Bates, I.R.4
Libich, D.S.5
Fares, C.6
-
150
-
-
84866728974
-
Adhesive properties and inflammatory potential of citrullinated myelin basic protein peptide 45-89
-
Shanshiashvili LV, Kalandadze IV, Ramsden JJ, Mikeladze DG Adhesive properties and inflammatory potential of citrullinated myelin basic protein peptide 45-89. Neurochem Res 2012, 37:1959-1966.
-
(2012)
Neurochem Res
, vol.37
, pp. 1959-1966
-
-
Shanshiashvili, L.V.1
Kalandadze, I.V.2
Ramsden, J.J.3
Mikeladze, D.G.4
-
151
-
-
20444446595
-
Transcriptional therapy with the histone deacetylase inhibitor trichostatin A ameliorates experimental autoimmune encephalomyelitis
-
Camelo S, Iglesias AH, Hwang D, et al. Transcriptional therapy with the histone deacetylase inhibitor trichostatin A ameliorates experimental autoimmune encephalomyelitis. J Neuroimmunol 2005, 164:10-21.
-
(2005)
J Neuroimmunol
, vol.164
, pp. 10-21
-
-
Camelo, S.1
Iglesias, A.H.2
Hwang, D.3
-
152
-
-
34248523169
-
Recovery of learning and memory is associated with chromatin remodelling
-
Fischer A, Sananbenesi F, Wang X, Dobbin M, Tsai LH Recovery of learning and memory is associated with chromatin remodelling. Nature 2007, 447:178-182.
-
(2007)
Nature
, vol.447
, pp. 178-182
-
-
Fischer, A.1
Sananbenesi, F.2
Wang, X.3
Dobbin, M.4
Tsai, L.H.5
-
153
-
-
76749091005
-
Inhibitors of class 1 histone deacetylases reverse contextual memory deficits in a mouse model of Alzheimer's disease
-
Kilgore M, Miller CA, Fass DM, et al. Inhibitors of class 1 histone deacetylases reverse contextual memory deficits in a mouse model of Alzheimer's disease. Neuropsychopharmacology 2010, 35:870-880.
-
(2010)
Neuropsychopharmacology
, vol.35
, pp. 870-880
-
-
Kilgore, M.1
Miller, C.A.2
Fass, D.M.3
-
154
-
-
68349152772
-
Histone deactylase inhibition combined with behavioral therapy enhances learning and memory following traumatic brain injury
-
Dash PK, Orsi SA, Moore AN Histone deactylase inhibition combined with behavioral therapy enhances learning and memory following traumatic brain injury. Neuroscience 2009, 163:1-8.
-
(2009)
Neuroscience
, vol.163
, pp. 1-8
-
-
Dash, P.K.1
Orsi, S.A.2
Moore, A.N.3
-
155
-
-
72749101742
-
Histone deacetylase inhibitor ITF2357 is neuroprotective, improves functional recovery, and induces glial apoptosis following experimental traumatic brain injury
-
Shein NA, Grigoriadis N, Alexandrovich AG, et al. Histone deacetylase inhibitor ITF2357 is neuroprotective, improves functional recovery, and induces glial apoptosis following experimental traumatic brain injury. FASEB J 2009, 23:4266-4275.
-
(2009)
FASEB J
, vol.23
, pp. 4266-4275
-
-
Shein, N.A.1
Grigoriadis, N.2
Alexandrovich, A.G.3
-
156
-
-
75549089982
-
HDAC1 nuclear export induced by pathological conditions is essential for the onset of axonal damage
-
Kim JY, Shen S, Dietz K, et al. HDAC1 nuclear export induced by pathological conditions is essential for the onset of axonal damage. Nat Neurosci 2010, 13:180-189.
-
(2010)
Nat Neurosci
, vol.13
, pp. 180-189
-
-
Kim, J.Y.1
Shen, S.2
Dietz, K.3
-
157
-
-
84870539847
-
Impaired adult myelination in the prefrontal cortex of socially isolated mice
-
Liu J, Dietz K, Deloyht JM, et al. Impaired adult myelination in the prefrontal cortex of socially isolated mice. Nat Neurosci 2012, 15:1621-1623.
-
(2012)
Nat Neurosci
, vol.15
, pp. 1621-1623
-
-
Liu, J.1
Dietz, K.2
Deloyht, J.M.3
|