Roles of GRK2 in cell signaling beyond GPCR desensitization: GRK2-HDAC6 interaction modulates cell spreading and motility

Science Signaling

Volumn 5, Issue 224, 2012, Pages

  Penela, Petronila ^a,b   Lafarga, Vanesa ^a,b   Tapia, Olga ^c   Rivas, Verónica ^a,b   Nogués, Laura ^a,b   Lucas, Elisa ^a,b   Vila Bedmar, Rocío ^a,b   Murga, Cristina ^a,b   Mayor, Federico ^a,b  

^a UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

^b Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas   (Spain)

^c UNIVERSITY OF CANTABRIA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

G PROTEIN COUPLED RECEPTOR KINASE 2; HISTONE DEACETYLASE 6; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN MDM2; TUBULIN; ADRBK1 PROTEIN, HUMAN; G PROTEIN COUPLED RECEPTOR; HDAC6 PROTEIN, HUMAN; HISTONE DEACETYLASE;

CELL ADHESION; CELL MIGRATION; CELL MOTILITY; CELL SPREADING; CHEMOTAXIS; DEACETYLATION; ENZYME ACTIVITY; EPITHELIUM CELL; HELA CELL; HISTONE ACETYLATION; HUMAN; INTRACELLULAR SIGNALING; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; REVIEW; SIGNAL TRANSDUCTION; ACETYLATION; ARTICLE; CELL MOTION; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; PROTEIN BINDING;

ACETYLATION; CELL MOVEMENT; G-PROTEIN-COUPLED RECEPTOR KINASE 2; HELA CELLS; HISTONE DEACETYLASES; HUMANS; PHOSPHORYLATION; PROTEIN BINDING; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION; TUBULIN;

EID: 84861118861     PISSN: 19450877     EISSN: 19379145     Source Type: Journal    
DOI: 10.1126/scisignal.2003098     Document Type: Review

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