Apamin inhibits hepatic fibrosis through suppression of transforming growth factor β1-induced hepatocyte epithelial-mesenchymal transition

Biochemical and Biophysical Research Communications

Volumn 450, Issue 1, 2014, Pages 195-201

  Lee, Woo Ram ^a   Kim, Kyung Hyun ^a   An, Hyun Jin ^a   Kim, Jung Yeon ^a   Lee, Sun Jae ^a   Han, Sang Mi ^b   Pak, Sok Cheon ^c   Park, Kwan Kyu ^a  

^a Catholic University of Daegu   (South Korea)

^b National Institute of Animal Science   (South Korea)

^c CHARLES STURT UNIVERSITY   (Australia)

Author keywords

Apamin; EMT; Hepatocyte; Liver fibrosis; TGF 1

Indexed keywords

APAMIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN KINASE B; SMAD2 PROTEIN; SMAD3 PROTEIN; SMAD4 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; UVOMORULIN; VIMENTIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL JUNCTION; CONTROLLED STUDY; DRUG MECHANISM; ENZYME PHOSPHORYLATION; EPITHELIAL MESENCHYMAL TRANSITION; EXPERIMENTAL LIVER FIBROSIS; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION;

ANIMALIA; APOIDEA;

APAMIN; CCL(4); EMT; HEPATOCYTE; LIVER FIBROSIS; TGF-Β1;

ANIMALS; APAMIN; CARBON TETRACHLORIDE; CELL LINE; EPITHELIAL-MESENCHYMAL TRANSITION; HEPATOCYTES; LIVER CIRRHOSIS; MALE; MICE; MICE, INBRED C57BL; TRANSFORMING GROWTH FACTOR BETA1; TREATMENT OUTCOME;

EID: 84904748893     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2014.05.089     Document Type: Article

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