Protective effects of melittin on transforming growth factor-β1 injury to hepatocytes via anti-apoptotic mechanism

Toxicology and Applied Pharmacology

Volumn 256, Issue 2, 2011, Pages 209-215

  Lee, Woo Ram ^a   Park, Ji Hyun ^a   Kim, Kyung Hyun ^a   Park, Yoon Yub ^a   Han, Sang Mi ^b   Park, Kwan kyu ^a  

^a Catholic University of Daegu   (South Korea)

^b National Institute of Animal Science   (South Korea)

Author keywords

Apoptosis; Hepatocytes; Liver disease; Melittin; TGF 1

Indexed keywords

APOPTOTIC PROTEASE ACTIVATING FACTOR 1; CASPASE; CASPASE 3; CASPASE 9; CYTOCHROME C; MELITTIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; PROTEIN BAX; PROTEIN BCL 2; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CYCLE REGULATION; CELL PROTECTION; CELL STRUCTURE; CELL SURVIVAL; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DNA DAMAGE; DRUG EFFECT; ENZYME INHIBITION; LIVER CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; NONHUMAN; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; CASPASES; CELL LINE; CELL SURVIVAL; CYTOCHROMES C; DRUG-INDUCED LIVER INJURY; FLOW CYTOMETRY; HEPATOCYTES; IMMUNOBLOTTING; MELITTEN; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; MITOCHONDRIA, LIVER; POLY(ADP-RIBOSE) POLYMERASES; PROTO-ONCOGENE PROTEINS C-BCL-2; TRANSFORMING GROWTH FACTOR BETA1;

APIS MELLIFERA; BACTERIA (MICROORGANISMS);

EID: 80053133552     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2011.08.012     Document Type: Article

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