Role of cathepsin B in regulating migration and invasion of fibroblast-like synoviocytes into inflamed tissue from patients with rheumatoid arthritis

Clinical and Experimental Immunology

Volumn 177, Issue 3, 2014, Pages 586-597

  Tong, B ^a   Wan, B ^b   Wei, Z ^a   Wang, T ^a   Zhao, P ^a   Dou, Y ^a   Lv, Z ^b   Xia, Y ^a   Dai, Y ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b THE FIRST AFFILIATED HOSPITAL OF NANJING MEDICAL UNIVERSITY   (China)

Author keywords

Cathepsin B; Invasion; Migration; Rheumatoid arthritis; Synoviocytes

Indexed keywords

CATHEPSIN B; CATHEPSIN B INHIBITOR; F ACTIN; FOCAL ADHESION KINASE; GELATINASE A; GELATINASE B; MESSENGER RNA; METHOTREXATE; MITOGEN ACTIVATED PROTEIN KINASE P38; NONSTEROID ANTIINFLAMMATORY AGENT; PREDNISONE; SALAZOSULFAPYRIDINE; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE;

ADULT; AGED; ARTICLE; CELL INVASION; CELL MIGRATION; CELL PROLIFERATION; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; EX VIVO STUDY; FEMALE; FIBROBLAST; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOREGULATION; JOINT DESTRUCTION; MALE; MIDDLE AGED; OSTEOARTHRITIS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; RHEUMATOID ARTHRITIS; RNA INTERFERENCE; SYNOVIOCYTE; SYNOVITIS; SYNOVIUM;

CATHEPSIN B; INVASION; MIGRATION; RHEUMATOID ARTHRITIS; SYNOVIOCYTES;

ACTINS; ADULT; ARTHRITIS, RHEUMATOID; CATHEPSIN B; CELL MOVEMENT; CELL PROLIFERATION; DIPEPTIDES; FEMALE; FIBROBLASTS; FOCAL ADHESION PROTEIN-TYROSINE KINASES; HUMANS; MALE; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MIDDLE AGED; MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PLATELET-DERIVED GROWTH FACTOR; RNA, SMALL INTERFERING; SYNOVIAL MEMBRANE; TRANSFECTION;

EID: 84904740862     PISSN: 00099104     EISSN: 13652249     Source Type: Journal    
DOI: 10.1111/cei.12357     Document Type: Article

References (39)

1. Niedermeier M, Pap T, Korb A. Therapeutic opportunities in fibroblasts in inflammatory arthritis. Best Pract Res Clin Rheumatol 2010; 24:527-540.
2. Yoshihara Y, Nakamura H, Obata K-I etal. Matrix metallo-proteinases and tissue inhibitors of metalloproteinases in synovial fluids from patients with rheumatoid arthritis orosteoarthritis. Ann Rheum Dis 2000; 59:455-461.
3. Lindy O, Konttinen YT, Sorsa T etal. Matrix metalloproteinase 13 (collagenase 13) in human rheumatoid synovium. Arthritis Rheum 1997; 40:1391-1399.
4. Vasiljeva O, Reinheckel T, Peters C, Turk D, Turk V, Turk B. Emerging roles of cathepasins in disease and their potential as drug targets. Curr Pharm Des 2007; 13:387-403.
5. Hashimoto Y, Kakegawa H, Narita Y etal. Significance of cathepsin B accumulation in synovial fluid of rheumatoid arthritis. Biochem Biophys Res Commun 2001; 283:334-339.
6. Hansen T, Petrow PK, Gaumann A etal. Cathepsin B and its endogenous inhibitor cystatin C in rheumatoid arthritis synovium. J Rheumatol 2000; 27:859-865.
7. Trabandt A, Gay RE, Fassbender HG, Gay S. Cathepsin B in synovial cells at the site of joint destruction in rheumatoid arthritis. Arthritis Rheum 1991; 34:1444-1451.
8. Arnett FC, Edworthy SM, Bloch DA etal. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 1988; 31:315-324.
9. Altman R, Asch E, Bloch D etal. Development of criteria for the classification and reporting of osteoarthritis: classification of osteoarthritis of the knee. Arthritis Rheum 1986; 29:1039-1049.
10. Lu Q, Lu S, Gao X etal. Norisoboldine, an alkaloid compound isolated from Radix Linderae, inhibits synovial angiogenesis in adjuvant-induced arthritis rats by moderating Notch1 pathway-related endothelial tip cell phenotype. Exp Biol Med (Maywood) 2012; 237:919-932.
11. Miller MC, Manning HB, Jain A etal. Membrane type1 matrix metalloproteinase is a crucial promoter of synovial invasion in human rheumatoid arthritis. Arthritis Rheum 2009; 60:686-697.
12. Wei Z, Wang F, Song J etal. Norisoboldine inhibits the production of interleukin-6 in fibroblast-like synoviocytes from adjuvant arthritis rats through PKC/MAPK/NF-κB-p65/CREB pathways. J Cell Biochem 2012; 113:2785-2795.
13. Lee S, Qiao J, Paul P, Chung DH. Integrin β1 is critical for gastrin-releasing peptide receptor-mediated neuroblastoma cell migration and invasion. Surgery 2013; 154:369-375.
14. Wu F, Bian D, Xia Y etal. Indentification of major active ingredients responsible for burn wound healing of centella asiatica herbs. Evid Based Complement Alternat Med 2012; 2012:848093.
15. Park HB, Yang JH, Chung KH. Characterization of the cytokine profile of platelet rich plasma (PRP) and PRP-induced cell proliferation and migration: upregulation of matrix metalloproteinase-1 and -9 in HaCaT cells. Korean J Hematol 2011; 46:265-273.
16. Tong B, Lu D, Wei Z, Wang T, Xia Y, Dai Y. Gleditsioside B, a triterpene saponin isolated from the anomalous fruits of Gleditsia sinensis Lam., abrogates bFGF-induced endothelial cell migration through preventing the activation of MMP-2 and FAK via inhibiting ERK and PI3K/AKT signaling pathways. Vascul Pharmacol 2013; 58:118-126.
17. Murnane MJ, Sheahan K, Ozdemirli M, Shuja S. Stage-specific increases in cathepsin B messenger RNA content in human colorectal carcinoma. Cancer Res 1991; 51:1137-1142.
18. Xu H, Song J, Gao X etal. Paeoniflorin attenuates lipopolysaccharide-induced permeability of endothelial cells: involvements of F-actin expression and phosphorylations of PI3K/Akt and PKC. Inflammation 2013; 36:216-225.
19. Hashimoto K, Morishige K, Sawada K etal. Geranylgeranylacetone inhibits lysophosphatidic acid-induced invasion of human ovarian carcinoma cells in vitro. Cancer 2005; 103:1529-1536.
20. Rempel SA, Rosenblum ML, Mikkelsen T etal. Cathepsin B expression and localization in glioma progression and invasion. Cancer Res 1994; 54:6027-6031.
21. Krepela E, Kasafirek E, Novak K, Viklicky J. Increased cathepsin B activity in human lung tumors. Neoplasma 1990; 37:61-70.
22. Sinha AA, Morgan JL, Buus RJ etal. Cathepsin B expression is similar in African-American and Caucasian prostate cancer patients. Anticancer Res 2007; 27:3135-3141.
23. Sinha AA, Gleason DF, Deleon OF, Wilson MJ, Sloane BF. Localization of a biotinylated cathepsin B oligonucleotide probe in human prostate including invasive cells and invasive edges by in situ hybridization. Anat Rec 1993; 235:233-240.
24. Krepela E, Vicar J, Cernoch M. Cathepsin B in human breast tumor tissue and cancer cells. Neoplasma 1989; 36:41-52.
25. Yin M, Soikkeli J, Jahkola T, Virolainen S, Saksela O, Hölttä E. TGF-β signaling, activated stromal fibroblasts, and cysteine cathepsins B and L drive the invasive growth of human melanoma cells. Am J Pathol 2012; 181:2202-2216.
26. Nomura T, Katunuma N. Involvement of cathepsins in the invasion, metastasis and proliferation of cancer cells. J Med Invest 2005; 52:1-9.
27. Gocheva V, Joyce JA. Cysteine cathepsins and the cutting edge of cancer invasion. Cell Cycle 2007; 6:60-64.
28. Szpaderska AM, Frankfater A. An intracellular form of cathepsin B contributes to invasiveness in cancer. Cancer Res 2001; 61:3493-3500.
29. Song C, Zhu S, Wu C, Kang J. HDAC10 suppresses cervical cancer metastasis through inhibition of matrix metalloproteinase (MMP) 2 and 9 expression. J Biol Chem 2013; 288:28021-28033.
30. Berube M, Deschambeault A, Boucher M, Germain L, Petitclerc E, Guérin SL. MMP-2 expression in uveal melanoma: differential activation status dictated by the cellular environment. Mol Vis 2005; 11:1101-1111.
31. Di Nezza LA, Misajon A, Zhang J etal. Presence of active gelatinases in endometrial carcinoma and correlation of matrix metalloproteinase expression with increasing tumor grade and invasion. Cancer 2002; 94:1466-1475.
32. Li G, Zhang Y, Qian Y etal. Interleukin-17A promotes rheumatoid arthritis synoviocytes migration and invasion under hypoxia by increasing MMP2 and MMP9 expression through NF-κB/HIF-1α pathway. Mol Immunol 2013; 53:227-236.
33. Kostoulas G, Lang A, Nagase H, Baici A. Stimulation of angiogenesis through cathepsin B inactivation of the tissue inhibitors of matrix metalloproteinases. FEBS Lett 1999; 455:286-290.
34. Premzl A, Turk V, Kos J. Intracelluar proteolytic activity of cathepsin B is associated with capillary-like tube formation by endothelial cells in vitro. J Cell Biochem 2006; 97:1230-1240.
35. Mitra SK, Schlaepfer DD. Integrin-regulated FAK-Src signaling in normal and cancer cells. Curr Opin Cell Biol 2006; 18:516-523.
36. Alapati K, Gopinath S, Malla RR, Dasari VR, Rao JS. uPAR and cathepsin B knockdown inhibits radiation-induced PKC integrated integrin signaling to the cytoskeleton of glioma-initiating cells. Int J Oncol 2012; 41:599-610.
37. Hsia DA, Mitra SK, Hauck CR etal. Differential regulation of cell motility and invasion by FAK. J Cell Biol 2003; 160:753-767.
38. Schlaepfer DD, Mitra SK. Multiple connections link FAK to cell motility and invasion. Curr Opin Genet Dev 2004; 14:92-101.
39. Nowicki TS, Zhao H, Darzynkiewicz Z etal. Downregulation of uPAR inhibits migration, invasion, proliferation, FAK/PI3K/Akt signaling and induces senescence in papillary thyroid carcinoma cells. Cell Cycle 2011; 10:100-107.