-
1
-
-
0023646810
-
Site-directed mutagenesis by gene targeting in mouse embryo- derived stem cells
-
Thomas K.R., Capecchi M.R. Site-directed mutagenesis by gene targeting in mouse embryo- derived stem cells. Cell 1987, 51:503-512.
-
(1987)
Cell
, vol.51
, pp. 503-512
-
-
Thomas, K.R.1
Capecchi, M.R.2
-
2
-
-
11944259305
-
-
Introduction of a lacZ reporter gene into the mouse int-2 locus by homologous recombination. Proc. Natl. Acad. Sci. U.S.A.
-
Mansour SL, Thomas KR, Deng CX, Capecchi MR (1990). Introduction of a lacZ reporter gene into the mouse int-2 locus by homologous recombination. Proc. Natl. Acad. Sci. U.S.A. 87, 7688-7692.
-
(1990)
, vol.87
, pp. 7688-7692
-
-
Mansour, S.L.1
Thomas, K.R.2
Deng, C.X.3
Capecchi, M.R.4
-
3
-
-
0034951142
-
-
Double-strand-break-induced homologous recombination in mammalian cells. Biochem. Soc.Trans. 29
-
Johnson RD, Jasin M (2001). Double-strand-break-induced homologous recombination in mammalian cells. Biochem. Soc.Trans. 29, 196-201.
-
(2001)
, pp. 196-201
-
-
Johnson, R.D.1
Jasin, M.2
-
4
-
-
0842287698
-
DNA double-strand break repair by homologous recombination
-
Dudas A., Chocanec M. DNA double-strand break repair by homologous recombination. Mutat. Res. 2004, 566:131-167.
-
(2004)
Mutat. Res.
, vol.566
, pp. 131-167
-
-
Dudas, A.1
Chocanec, M.2
-
5
-
-
74249095519
-
-
CRISPR/Cas, the immune system of bacteria and archaea. Science 327
-
Horvath P, Barrangou R (2010). CRISPR/Cas, the immune system of bacteria and archaea. Science 327, 167-170.
-
(2010)
, pp. 167-170
-
-
Horvath, P.1
Barrangou, R.2
-
6
-
-
80755187812
-
CRISPR-Cas systems in bacteria and archaea: versatile small RNAs for adaptive defense and regulation
-
Bhaya D., Davison M., Barrangou R. CRISPR-Cas systems in bacteria and archaea: versatile small RNAs for adaptive defense and regulation. Annu. Rev. Genet. 2011, 45:273-297.
-
(2011)
Annu. Rev. Genet.
, vol.45
, pp. 273-297
-
-
Bhaya, D.1
Davison, M.2
Barrangou, R.3
-
7
-
-
84866138092
-
RNA-mediated programmable DNA cleavage
-
Barrangou R. RNA-mediated programmable DNA cleavage. Nat. Biotech. 2012, 30:836-838.
-
(2012)
Nat. Biotech.
, vol.30
, pp. 836-838
-
-
Barrangou, R.1
-
8
-
-
84874624936
-
Targeted genome engineering in human cells with the Cas9 RNA-guided endonuclease
-
Cho S.W., Kim S., Kim J.M., Kim J. Targeted genome engineering in human cells with the Cas9 RNA-guided endonuclease. Nat. Biotech. 2013, 31:230-232.
-
(2013)
Nat. Biotech.
, vol.31
, pp. 230-232
-
-
Cho, S.W.1
Kim, S.2
Kim, J.M.3
Kim, J.4
-
9
-
-
84873734105
-
-
RNA-guided human genome engineering via Cas9. Science 339,
-
Mali P., Yang L., Esvelt K.M., Arch J, Guell M., DiCarlo J.E., Norville J.E., Church G.M. (2013). RNA-guided human genome engineering via Cas9. Science 339, 823-826.
-
(2013)
, pp. 823-826
-
-
Mali, P.1
Yang, L.2
Esvelt, K.M.3
Arch, J.4
Guell, M.5
DiCarlo, J.E.6
Norville, J.E.7
Church, G.M.8
-
10
-
-
84892749369
-
Genetic screens in human cells using the CRISPR-Cas9 system
-
Wang R., Wei J.J., Sabatini D.M., Lander E.S. Genetic screens in human cells using the CRISPR-Cas9 system. Science 2013, 343:80-84.
-
(2013)
Science
, vol.343
, pp. 80-84
-
-
Wang, R.1
Wei, J.J.2
Sabatini, D.M.3
Lander, E.S.4
-
11
-
-
84880088705
-
-
Genome engineering of Drosophila with the CRISPR RNA-guided CAS9 nuclease. Genetics 194,
-
Gratz S.J., Cummings A.M., Nguyen J.N., Hamm D.C., Donohue L.K., Harrison M.M., Wildonger J., O'Connor-Giles K.M. (2013). Genome engineering of Drosophila with the CRISPR RNA-guided CAS9 nuclease. Genetics 194, 1029-1035.
-
(2013)
, pp. 1029-1035
-
-
Gratz, S.J.1
Cummings, A.M.2
Nguyen, J.N.3
Hamm, D.C.4
Donohue, L.K.5
Harrison, M.M.6
Wildonger, J.7
O'Connor-Giles, K.M.8
-
12
-
-
84888108873
-
-
Optimized gene editing technology for Drosophila melanogaster using germ line-specific Cas9. Proc. Natl. Acad. Sci. USA 110
-
Ren X., Sun J., Housden B.E., Hu Y., Roesel C., Lin S., Liu L.P., Yang Z., Mao D., Sun L. et al. (2013). Optimized gene editing technology for Drosophila melanogaster using germ line-specific Cas9. Proc. Natl. Acad. Sci. USA 110, 19012-19017.
-
(2013)
, pp. 19012-19017
-
-
Ren, X.1
Sun, J.2
Housden, B.E.3
Hu, Y.4
Roesel, C.5
Lin, S.6
Liu, L.P.7
Yang, Z.8
Mao, D.9
Sun, L.10
-
13
-
-
84876409836
-
-
Genome editing with RNA-guided Cas9 nuclease in Zebrafish embryos. Nature23,
-
Chang N., Sun C., Gao L., Zhu D., Xu X., Zhu X., Xiong J, Xi J.J. (2013). Genome editing with RNA-guided Cas9 nuclease in Zebrafish embryos. Nature23, 465-472.
-
(2013)
, pp. 465-472
-
-
Chang, N.1
Sun, C.2
Gao, L.3
Zhu, D.4
Xu, X.5
Zhu, X.6
Xiong, J.7
Xi, J.J.8
-
14
-
-
84874617789
-
-
Efficient genome editing in zebrafish using a CRISPR-Cas system. Nature 31
-
Hwang WY, Fu Y, Reyon D, Maeder ML, Tsai SQ, Sander JD, Peterson RT, Yeh JR & Joung JK (2013). Efficient genome editing in zebrafish using a CRISPR-Cas system. Nature 31, 227-229.
-
(2013)
, pp. 227-229
-
-
Hwang, W.Y.1
Fu, Y.2
Reyon, D.3
Maeder, M.L.4
Tsai, S.Q.5
Sander, J.D.6
Peterson, R.T.7
Yeh, J.R.8
Joung, J.K.9
-
15
-
-
84889589440
-
Generation of mutant mice by pronuclear injection of circular plasmid expressing Cas9 and single guided RNA
-
Mashiko D., Fujihara Y., Satouh Y., Miyata H., Isotani A., Ikawa M. Generation of mutant mice by pronuclear injection of circular plasmid expressing Cas9 and single guided RNA. Sci. Rep. 2013, 3:1-6.
-
(2013)
Sci. Rep.
, vol.3
, pp. 1-6
-
-
Mashiko, D.1
Fujihara, Y.2
Satouh, Y.3
Miyata, H.4
Isotani, A.5
Ikawa, M.6
-
16
-
-
84877103949
-
Generation of gene-modified mice via Cas9/RNA-mediated gene targeting
-
Shen B., Zhang J., Wu H., Wang J., Ma K., Li Z., Zhang X., Zhang P., Huang X. Generation of gene-modified mice via Cas9/RNA-mediated gene targeting. Cell Res. 2013, 5:720-723.
-
(2013)
Cell Res.
, vol.5
, pp. 720-723
-
-
Shen, B.1
Zhang, J.2
Wu, H.3
Wang, J.4
Ma, K.5
Li, Z.6
Zhang, X.7
Zhang, P.8
Huang, X.9
-
17
-
-
84883819602
-
-
Heritable gene targeting in the mouse and rat using a CRISPR-Cas system. Nat. Biotechnol. 8
-
Li D, Qiu Z, Shao Y, Chen Y, Guan Y, Liu M, Li Y, Gao N, Wang L, Lu X. et al. (2013) Heritable gene targeting in the mouse and rat using a CRISPR-Cas system. Nat. Biotechnol. 8, 681-683.
-
(2013)
, pp. 681-683
-
-
Li, D.1
Qiu, Z.2
Shao, Y.3
Chen, Y.4
Guan, Y.5
Liu, M.6
Li, Y.7
Gao, N.8
Wang, L.9
Lu, X.10
-
18
-
-
84894081986
-
Generation of gene-modified cynomolgus monkey via Cas9/RNA-mediated gene targeting in one-cell embryos
-
Niu Y., Shen B., Cui Y., Chen Y., Wang J., Wang L., Kang Y., Zhao X., Si W., Xiang A.P., et al. Generation of gene-modified cynomolgus monkey via Cas9/RNA-mediated gene targeting in one-cell embryos. Cell 2013, 156:836-843.
-
(2013)
Cell
, vol.156
, pp. 836-843
-
-
Niu, Y.1
Shen, B.2
Cui, Y.3
Chen, Y.4
Wang, J.5
Wang, L.6
Kang, Y.7
Zhao, X.8
Si, W.9
Xiang, A.P.10
-
19
-
-
84880570576
-
High-frequency off-target mutagenesis induced by CRISPR-Cas nuclease in human cells
-
Fu Y., Foden J.A., Khayter C., Maeder M.L., Reyon D., Joung J.K., Sander J.D. High-frequency off-target mutagenesis induced by CRISPR-Cas nuclease in human cells. Nat. Biotechnol. 2013, 9:822-826.
-
(2013)
Nat. Biotechnol.
, vol.9
, pp. 822-826
-
-
Fu, Y.1
Foden, J.A.2
Khayter, C.3
Maeder, M.L.4
Reyon, D.5
Joung, J.K.6
Sander, J.D.7
-
20
-
-
84884155038
-
-
High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity. Nat. Biotechnol. l9
-
Pattanayak V, Lin S, Guilinger JP, Ma E, Doudna JA, Liu DR (2013). High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity. Nat. Biotechnol. l9, 839-843.
-
(2013)
, pp. 839-843
-
-
Pattanayak, V.1
Lin, S.2
Guilinger, J.P.3
Ma, E.4
Doudna, J.A.5
Liu, D.R.6
-
21
-
-
84866859751
-
-
Cas9-crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria. Proc. Natl. Acad. Sci. U.S.A.
-
Gasiunas G., Barrangou R., Horvath P., Siksnys V. (2012). Cas9-crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria. Proc. Natl. Acad. Sci. U.S.A. 109, E2579-E2586.
-
(2012)
, vol.109
-
-
Gasiunas, G.1
Barrangou, R.2
Horvath, P.3
Siksnys, V.4
-
22
-
-
84887010498
-
Genome engineering the CRISPR-Cas9 system
-
(21)
-
Ran F., Hsu P.D., Wright J., Agarwala V., Scott D., Zhang F. Genome engineering the CRISPR-Cas9 system. Nat. Protoc. 2013, 11:2281-2308. (21).
-
(2013)
Nat. Protoc.
, vol.11
, pp. 2281-2308
-
-
Ran, F.1
Hsu, P.D.2
Wright, J.3
Agarwala, V.4
Scott, D.5
Zhang, F.6
-
23
-
-
84873729095
-
Multiplex genome engineering using CRISPR/Cas systems
-
Cong L., Ran F.A., Cox D., Lin S., Barretto R., Habib N., Hsu P.D., Wu X., Jiang W., Marraffini L.A., et al. Multiplex genome engineering using CRISPR/Cas systems. Science 2013, 339:819-823.
-
(2013)
Science
, vol.339
, pp. 819-823
-
-
Cong, L.1
Ran, F.A.2
Cox, D.3
Lin, S.4
Barretto, R.5
Habib, N.6
Hsu, P.D.7
Wu, X.8
Jiang, W.9
Marraffini, L.A.10
-
24
-
-
84884160273
-
CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering
-
Mali P., Aach J., Stranges P.B., Esvelt K.M., Moosburner M., Kosuri S., Yang L., Church G.M. CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering. Nat. Biotechnol. 2013, 9:833-838.
-
(2013)
Nat. Biotechnol.
, vol.9
, pp. 833-838
-
-
Mali, P.1
Aach, J.2
Stranges, P.B.3
Esvelt, K.M.4
Moosburner, M.5
Kosuri, S.6
Yang, L.7
Church, G.M.8
-
25
-
-
84884288934
-
Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity
-
Ran F.A., Hsu P.D., Lin C., Gootenberg J.S., Konermann S., Trevino A.E., Scott D.A., Inoue A., Matoba S., Zhang Y., et al. Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity. Cell 2013, 154:1380-1389.
-
(2013)
Cell
, vol.154
, pp. 1380-1389
-
-
Ran, F.A.1
Hsu, P.D.2
Lin, C.3
Gootenberg, J.S.4
Konermann, S.5
Trevino, A.E.6
Scott, D.A.7
Inoue, A.8
Matoba, S.9
Zhang, Y.10
-
26
-
-
84897954175
-
Efficient genome modification by CRISPR-Cas9 nickase with minimal off-target effects
-
Shen B., Zhang W., Zhang J., Zhou J., Wang J., Chen L., Wang L., Hodgkins A., Iyer V., Huang X. Efficient genome modification by CRISPR-Cas9 nickase with minimal off-target effects. Nat. Methods 2014, 11:399-402.
-
(2014)
Nat. Methods
, vol.11
, pp. 399-402
-
-
Shen, B.1
Zhang, W.2
Zhang, J.3
Zhou, J.4
Wang, J.5
Chen, L.6
Wang, L.7
Hodgkins, A.8
Iyer, V.9
Huang, X.10
-
27
-
-
84877707375
-
One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering
-
Wang H., Yang H., Shivalila C.S., Dawlaty M.M., Cheng A.W., Zhang F., Jaenisch R. One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering. Cell 2013, 153:1-9.
-
(2013)
Cell
, vol.153
, pp. 1-9
-
-
Wang, H.1
Yang, H.2
Shivalila, C.S.3
Dawlaty, M.M.4
Cheng, A.W.5
Zhang, F.6
Jaenisch, R.7
-
28
-
-
84884289608
-
One-step generation of mice carrying reporter and conditional alleles by CRISPR/Cas-mediate genome engineering
-
Yang H., Wang H., Shivalila C.S., Cheng A.W., Shi L., Jaenisch R. One-step generation of mice carrying reporter and conditional alleles by CRISPR/Cas-mediate genome engineering. Cell 2013, 154:1370-1379.
-
(2013)
Cell
, vol.154
, pp. 1370-1379
-
-
Yang, H.1
Wang, H.2
Shivalila, C.S.3
Cheng, A.W.4
Shi, L.5
Jaenisch, R.6
-
29
-
-
0028059099
-
Deletion of a DNA polymerase beta gene targeting segment in T cells using cell type specific gene targeting
-
Gu H., Marth J.D., Orban P.C., Mossmann H., Rajewsky K. Deletion of a DNA polymerase beta gene targeting segment in T cells using cell type specific gene targeting. Science 1994, 265:103-106.
-
(1994)
Science
, vol.265
, pp. 103-106
-
-
Gu, H.1
Marth, J.D.2
Orban, P.C.3
Mossmann, H.4
Rajewsky, K.5
-
30
-
-
0029959207
-
Conditional gene targeting
-
Rajewsky K., Gu H., Kuhn R., Betz U.A.K., Muller W., Roes J., Schwenk F. Conditional gene targeting. J. Clin. Invest. 1996, 98:600-603.
-
(1996)
J. Clin. Invest.
, vol.98
, pp. 600-603
-
-
Rajewsky, K.1
Gu, H.2
Kuhn, R.3
Betz, U.A.K.4
Muller, W.5
Roes, J.6
Schwenk, F.7
-
31
-
-
79959210305
-
-
A conditional knockout resource for the genome-widestudy of mouse gene function. Nature
-
Skarnes, W.C., Rosen, B., West, A.P., Koutsourakis, M., Bushell, W., Iyer, V., Mujica, A.O., Thomas, M., Harrow J., Cox T. et al. (2011). A conditional knockout resource for the genome-widestudy of mouse gene function. Nature 474, 337-342.
-
(2011)
, vol.474
, pp. 337-342
-
-
Skarnes, W.C.1
Rosen, B.2
West, A.P.3
Koutsourakis, M.4
Bushell, W.5
Iyer, V.6
Mujica, A.O.7
Thomas, M.8
Harrow, J.9
Cox, T.10
-
32
-
-
84891745242
-
Generating rats with conditional alleles using CRISPR/Cas9
-
Ma Y., Zhang X., Shen B., Lu Y., Chen W., Ma J., Bai L., Huang X., Zhang L. Generating rats with conditional alleles using CRISPR/Cas9. Cell Res. 2014, 24:122-125.
-
(2014)
Cell Res.
, vol.24
, pp. 122-125
-
-
Ma, Y.1
Zhang, X.2
Shen, B.3
Lu, Y.4
Chen, W.5
Ma, J.6
Bai, L.7
Huang, X.8
Zhang, L.9
-
33
-
-
84872696903
-
Dystroglycan organizes axon guidance cue localization and axonal pathfinding
-
Wright K.M., Lyon K.A., Leung H., Leahy D.J., Ma L., Ginty D.D. Dystroglycan organizes axon guidance cue localization and axonal pathfinding. Neuron 2012, 76:913-944.
-
(2012)
Neuron
, vol.76
, pp. 913-944
-
-
Wright, K.M.1
Lyon, K.A.2
Leung, H.3
Leahy, D.J.4
Ma, L.5
Ginty, D.D.6
-
34
-
-
84860322514
-
Mutations in ISPD cause Walker-Warburg syndrome and defective glycosylation of α-dystroglycan
-
Roscioli T., Kamsteeg E.J., Buysse K., Maystadt I., Van Reeuwijk J., Van Den Elzen C., Van Beusekom E., Riemersma M., Pfundt R., Vissers L.E., et al. Mutations in ISPD cause Walker-Warburg syndrome and defective glycosylation of α-dystroglycan. Nat. Genet. 2012, 44:581-585.
-
(2012)
Nat. Genet.
, vol.44
, pp. 581-585
-
-
Roscioli, T.1
Kamsteeg, E.J.2
Buysse, K.3
Maystadt, I.4
Van Reeuwijk, J.5
Van Den Elzen, C.6
Van Beusekom, E.7
Riemersma, M.8
Pfundt, R.9
Vissers, L.E.10
-
35
-
-
84860348118
-
ISPD loss-of-function mutations disrupt dystroglycan O-mannosylation and cause Walker-Warburg syndrome
-
Wiler T., Lee H., Lommel M., Yoshida-Moriguchi T., De Bernabe D.B., Venzke D., Cirak S., Schachter H., Vajsar J., Voit T., et al. ISPD loss-of-function mutations disrupt dystroglycan O-mannosylation and cause Walker-Warburg syndrome. Nat. Genet. 2012, 44:575-580.
-
(2012)
Nat. Genet.
, vol.44
, pp. 575-580
-
-
Wiler, T.1
Lee, H.2
Lommel, M.3
Yoshida-Moriguchi, T.4
De Bernabe, D.B.5
Venzke, D.6
Cirak, S.7
Schachter, H.8
Vajsar, J.9
Voit, T.10
|