메뉴 건너뛰기




Volumn 37, Issue 7, 2014, Pages 501-520

Are the safety profiles of antipsychotic drugs used in dementia the same? An updated review of observational studies

Author keywords

[No Author keywords available]

Indexed keywords

AMISULPRIDE; ARIPIPRAZOLE; ASENAPINE; ATYPICAL ANTIPSYCHOTIC AGENT; CLOZAPINE; HALOPERIDOL; NEUROLEPTIC AGENT; OLANZAPINE; PEROSPIRONE; PIPAMPERONE; QUETIAPINE; RISPERIDONE; ZIPRASIDONE;

EID: 84904728420     PISSN: 01145916     EISSN: 11791942     Source Type: Journal    
DOI: 10.1007/s40264-014-0170-y     Document Type: Review
Times cited : (36)

References (126)
  • 3
    • 78650480296 scopus 로고    scopus 로고
    • Atypical antipsychotics for the treatment of behavioral and psychological symptoms in dementia, with a particular focus on longer term outcomes and mortality
    • Ballard C, Creese B, Corbett A, Aarsland D. Atypical antipsychotics for the treatment of behavioral and psychological symptoms in dementia, with a particular focus on longer term outcomes and mortality. Expert Opin Drug Saf 2011;10(1):35-43.
    • (2011) Expert Opin Drug Saf , vol.10 , Issue.1 , pp. 35-43
    • Ballard, C.1    Creese, B.2    Corbett, A.3    Aarsland, D.4
  • 4
    • 21044434765 scopus 로고    scopus 로고
    • The effect of staff training on the use of restraint in dementia: A single-blind randomised controlled trial
    • DOI 10.1002/gps.1329
    • Testad I, Aasland AM, Aarsland D. The effect of staff training on the use of restraint in dementia: a single-blind randomised controlled trial. Int J Geriatr Psychiatry. 2005;20(6):587-90. (Pubitemid 40873352)
    • (2005) International Journal of Geriatric Psychiatry , vol.20 , Issue.6 , pp. 587-590
    • Testad, I.1    Aasland, A.M.2    Aarsland, D.3
  • 5
    • 50349096198 scopus 로고    scopus 로고
    • The course of psychiatric and behavioral symptoms and the use of psychotropic medication in patients with dementia in Norwegian nursing homes: A 12-month follow-up study
    • Selbaek G, Kirkevold O, Engedal K. The course of psychiatric and behavioral symptoms and the use of psychotropic medication in patients with dementia in Norwegian nursing homes: a 12-month follow-up study. Am J Geriatr Psychiatry. 2008;16(7):528-36.
    • (2008) Am J Geriatr Psychiatry , vol.16 , Issue.7 , pp. 528-536
    • Selbaek, G.1    Kirkevold, O.2    Engedal, K.3
  • 6
    • 0025175970 scopus 로고
    • Survival of outpatients with Alzheimer-type dementia
    • Walsh JS, Welch HG, Larson EB. Survival of outpatients with Alzheimer-type dementia. Ann Intern Med. 1990;113(6):429-34. (Pubitemid 20333450)
    • (1990) Annals of Internal Medicine , vol.113 , Issue.6 , pp. 429-434
    • Walsh, J.S.1    Welch, H.G.2    Larson, E.B.3
  • 7
    • 84880598437 scopus 로고    scopus 로고
    • Behavioural and psychological symptoms of dementia, cognitive impairment and caregiver burden in patients with dementia
    • Rosdinom R, Zarina MZ, Zanariah MS, Marhani M, Suzaily W. Behavioural and psychological symptoms of dementia, cognitive impairment and caregiver burden in patients with dementia. Prev Med. 2013;57 Suppl:S67-9
    • (2013) Prev Med , vol.57 , Issue.SUPPL.
    • Rosdinom, R.1    Zarina, M.Z.2    Zanariah, M.S.3    Marhani, M.4    Suzaily, W.5
  • 8
    • 84862792198 scopus 로고    scopus 로고
    • Treatment of behavioral and psychological symptoms of Alzheimer's disease
    • Corbett A, Smith J, Creese B, Ballard C. Treatment of behavioral and psychological symptoms of Alzheimer's disease. Curr Treat Options Neurol. 2012;14(2):113-25.
    • (2012) Curr Treat Options Neurol , vol.14 , Issue.2 , pp. 113-125
    • Corbett, A.1    Smith, J.2    Creese, B.3    Ballard, C.4
  • 9
    • 47749146154 scopus 로고    scopus 로고
    • Antipsychotics for the treatment of Behavioral and Psychological Symptoms of Dementia (BPSD)
    • DOI 10.2174/157015908784533860
    • Liperoti R, Pedone C, Corsonello A. Antipsychotics for the treatment of behavioral and psychological symptoms of dementia (BPSD). Curr Neuropharmacol. 2008;6(2):117-24. (Pubitemid 352024796)
    • (2008) Current Neuropharmacology , vol.6 , Issue.2 , pp. 117-124
    • Liperoti, R.1    Pedone, C.2    Corsonello, A.3
  • 10
    • 0036110428 scopus 로고    scopus 로고
    • Pharmacology of atypical antipsychotics
    • DOI 10.1097/00002826-200205000-00005
    • Factor SA. Pharmacology of atypical antipsychotics. Clin Neuropharmacol. 2002;25(3):153-7. (Pubitemid 34556424)
    • (2002) Clinical Neuropharmacology , vol.25 , Issue.3 , pp. 153-157
    • Factor, S.A.1
  • 11
    • 58649100010 scopus 로고    scopus 로고
    • Asenapine: A novel psychopharmacologic agent with a unique human receptor signature
    • Shahid M, Walker GB, Zorn SH, Wong EH. Asenapine: a novel psychopharmacologic agent with a unique human receptor signature. J Psychopharmacol. 2009;23(1):65.-73.
    • (2009) J Psychopharmacol , vol.23 , Issue.1 , pp. 65-73
    • Shahid, M.1    Walker, G.B.2    Zorn, S.H.3    Wong, E.H.4
  • 13
  • 15
    • 17644392108 scopus 로고    scopus 로고
    • Antipsychotic prescribing pattern among Italian general practitioners: A population-based study during the years 1999-2002
    • DOI 10.1007/s00228-004-0868-3
    • Trifiro G, Spina E, Brignoli O, Sessa E, Caputi AP, Mazzaglia G. Antipsychotic prescribing pattern among Italian general practitioners: a population-based study during the years 1999-2002. Eur J Clin Pharmacol. 2005;61(1):47-53. (Pubitemid 40558279)
    • (2005) European Journal of Clinical Pharmacology , vol.61 , Issue.1 , pp. 47-53
    • Trifiro, G.1    Spina, E.2    Brignoli, O.3    Sessa, E.4    Caputi, A.P.5    Mazzaglia, G.6
  • 16
    • 33645527991 scopus 로고    scopus 로고
    • The effectiveness of atypical antipsychotics for the treatment of aggression and psychosis in Alzheimer's disease
    • Ballard C, Waite J. The effectiveness of atypical antipsychotics for the treatment of aggression and psychosis in Alzheimer's disease. Cochrane Database Syst Rev. 2006;(1):CD003476.
    • (2006) Cochrane Database Syst Rev , Issue.1
    • Ballard, C.1    Waite, J.2
  • 17
    • 34250658026 scopus 로고    scopus 로고
    • Meta-analysis of the effectiveness of atypical antipsychotics for the treatment of behavioural problems in persons with dementia
    • DOI 10.1159/000101499
    • Yury CA, Fisher JE. Meta-analysis of the effectiveness of atypical antipsychotics for the treatment of behavioural problems in persons with dementia. Psychother Psychosom. 2007;76(4):213-8. (Pubitemid 46933366)
    • (2007) Psychotherapy and Psychosomatics , vol.76 , Issue.4 , pp. 213-218
    • Yury, C.A.1    Fisher, J.E.2
  • 19
    • 80053215800 scopus 로고    scopus 로고
    • Efficacy and comparative effectiveness of atypical antipsychotic medications for off-label uses in adults: A systematic review and meta-analysis
    • Maher AR, Maglione M, Bagley S, Suttorp M, Hu JH, Ewing B, et al. Efficacy and comparative effectiveness of atypical antipsychotic medications for off-label uses in adults: a systematic review and meta-analysis. JAMA. 2011;306(12):1359-69.
    • (2011) JAMA , vol.306 , Issue.12 , pp. 1359-1369
    • Maher, A.R.1    Maglione, M.2    Bagley, S.3    Suttorp, M.4    Hu, J.H.5    Ewing, B.6
  • 20
    • 84865840009 scopus 로고    scopus 로고
    • Antipsychotics in dementia: Prevalence and quality of antipsychotic drug prescribing in UK mental health services
    • Barnes TR, Banerjee S, Collins N, Treloar A, McIntyre SM, Paton C. Antipsychotics in dementia: prevalence and quality of antipsychotic drug prescribing in UK mental health services. Br J Psychiatry. 2012;201(3):221-6.
    • (2012) Br J Psychiatry , vol.201 , Issue.3 , pp. 221-226
    • Barnes, T.R.1    Banerjee, S.2    Collins, N.3    Treloar, A.4    McIntyre, S.M.5    Paton, C.6
  • 21
    • 58149236875 scopus 로고    scopus 로고
    • Use of antipsychotics in elderly patients with dementia: Do atypical and conventional agents have a similar safety profile?
    • Trifirò G, Spina E, Gambassi G. Use of antipsychotics in elderly patients with dementia: do atypical and conventional agents have a similar safety profile? Pharmacol Res. 2009;59:1-12.
    • (2009) Pharmacol Res , vol.59 , pp. 1-12
    • Trifirò, G.1    Spina, E.2    Gambassi, G.3
  • 22
    • 50649116606 scopus 로고    scopus 로고
    • Effect of regulatory warnings on antipsychotic prescription rates among elderly patients with dementia: A population-based time-series analysis
    • Valiyeva E, Herrmann N, Rochon PA, Gill SS, Anderson GM. Effect of regulatory warnings on antipsychotic prescription rates among elderly patients with dementia: a population-based time-series analysis. CMAJ. 2008;179(5):438-46.
    • (2008) CMAJ , vol.179 , Issue.5 , pp. 438-446
    • Valiyeva, E.1    Herrmann, N.2    Rochon, P.A.3    Gill, S.S.4    Anderson, G.M.5
  • 23
    • 73449130136 scopus 로고    scopus 로고
    • Prescribing pattern of antipsychotic drugs in the Italian general population 2000-2005: A focus on elderly with dementia
    • Trifiro G, Sini G, Sturkenboom MC, Vanacore N, Mazzaglia G, Caputi AP, et al. Prescribing pattern of antipsychotic drugs in the Italian general population 2000-2005: a focus on elderly with dementia. Int Clin Psychopharmacol. 2010;25(1):22-8.
    • (2010) Int Clin Psychopharmacol , vol.25 , Issue.1 , pp. 22-28
    • Trifiro, G.1    Sini, G.2    Sturkenboom, M.C.3    Vanacore, N.4    Mazzaglia, G.5    Caputi, A.P.6
  • 26
    • 33745737632 scopus 로고    scopus 로고
    • Neuroleptic drugs in dementia: Benefits and harm
    • DOI 10.1038/nrn1926, PII NRN1926
    • Ballard C, Howard R. Neuroleptic drugs in dementia: benefits and harm. Nat Rev. 2006;7(6):492-500. (Pubitemid 44012289)
    • (2006) Nature Reviews Neuroscience , vol.7 , Issue.6 , pp. 492-500
    • Ballard, C.1    Howard, R.2
  • 27
    • 34249828144 scopus 로고    scopus 로고
    • cited 16 Apr 14. Available from
    • National Institute of Health and Care Excellence. Dementia: supporting people with dementia and their carers in health and social care. 2006 (cited 16 Apr 14). Available from: http://pathways.nice.org.uk/pathways/dementia#path= view%3A/pathways/dementia/dementia-interventions.xml&content= view-node%3Anodes-pharmacological-interventions-for-non-cognitive-symptoms.
    • (2006) Dementia: Supporting People with Dementia and Their Carers in Health and Social Care
  • 28
    • 57749191241 scopus 로고    scopus 로고
    • The critical role of clinical pharmacology in geriatric psychopharmacology
    • Pollock B, Forsyth C, Bies R. The critical role of clinical pharmacology in geriatric psychopharmacology. Clin Pharmacol Ther. 2009;85(1):89-93.
    • (2009) Clin Pharmacol Ther , vol.85 , Issue.1 , pp. 89-93
    • Pollock, B.1    Forsyth, C.2    Bies, R.3
  • 29
    • 79961039191 scopus 로고    scopus 로고
    • Age-related changes in pharmacodynamics: Focus on drugs acting on central nervous and cardiovascular systems
    • Trifiro G, Spina E. Age-related changes in pharmacodynamics: focus on drugs acting on central nervous and cardiovascular systems. Curr Drug Metab. 2011;12(7):611-20.
    • (2011) Curr Drug Metab , vol.12 , Issue.7 , pp. 611-620
    • Trifiro, G.1    Spina, E.2
  • 30
    • 37249022281 scopus 로고    scopus 로고
    • A roadmap to key pharmacologic principles in using antipsychotics
    • A roadmap to key pharmacologic principles in using antipsychotics. Prim Care Companion J Clin Psychiatry. 2007;9(6):444-54.
    • (2007) Prim Care Companion J Clin Psychiatry , vol.9 , Issue.6 , pp. 444-454
  • 32
    • 20444502908 scopus 로고    scopus 로고
    • European Medicines Agency. cited 18 Sep 2013. Available from
    • European Medicines Agency. EMEA public statement on the safety of olanzapine (Zyprexa, Zyprexa Velotab). 2004 (cited 18 Sep 2013). Available from: http://www.bfarm.de/SharedDocs/Downloads/DE/Arzneimittel/Pharmakovigilanz/ Service/aktuelles/emea-zyprexa-st.pdf?-blob=publicationFile&v=2.
    • (2004) EMEA Public Statement on the Safety of Olanzapine (Zyprexa, Zyprexa Velotab)
  • 33
    • 26844538114 scopus 로고    scopus 로고
    • Risk of death with atypical antipsychotic drug treatment for dementia: Meta-analysis of randomized placebo-controlled trials
    • DOI 10.1001/jama.294.15.1934
    • Schneider LS, Dagerman KS, Insel P. Risk of death with atypical antipsychotic drug treatment for dementia: meta-analysis of randomized placebo-controlled trials. Jama. 2005;294(15):1934-43. (Pubitemid 41464695)
    • (2005) Journal of the American Medical Association , vol.294 , Issue.15 , pp. 1934-1943
    • Schneider, L.S.1    Dagerman, K.S.2    Insel, P.3
  • 34
    • 79957990483 scopus 로고    scopus 로고
    • Available from
    • US FDA. Information on conventional antipsychotics. 2008. Available from: http://www.fda.gov/drugs/drugsafety/ postmarketdrugsafetyinformationforpatientsandproviders/ucm107211.htm.
    • (2008) Information on Conventional Antipsychotics
  • 36
    • 33947264305 scopus 로고    scopus 로고
    • Risk of death associated with the use of conventional versus atypical antipsychotic drugs among elderly patients
    • DOI 10.1503/cmaj.061250
    • Schneeweiss S, Setoguchi S, Brookhart A, Dormuth C, Wang PS. Risk of death associated with the use of conventional versus atypical antipsychotic drugs among elderly patients. CMAJ. 2007;176(5):627-32. (Pubitemid 46426056)
    • (2007) Canadian Medical Association Journal , vol.176 , Issue.5 , pp. 627-632
    • Schneeweiss, S.1    Setoguchi, S.2    Brookhart, A.3    Dormuth, C.4    Wang, P.S.5
  • 37
    • 35748963236 scopus 로고    scopus 로고
    • Mortality risk in patients with dementia treated with antipsychotics versus other psychiatric medications
    • quiz 623
    • Kales HC, Valenstein M, Kim HM, McCarthy JF, Ganoczy D, Cunningham F, et al. Mortality risk in patients with dementia treated with antipsychotics versus other psychiatric medications. Am J Psychiatry. 2007;164(10):1568-76;quiz 623.
    • (2007) Am J Psychiatry , vol.164 , Issue.10 , pp. 1568-1576
    • Kales, H.C.1    Valenstein, M.2    Kim, H.M.3    McCarthy, J.F.4    Ganoczy, D.5    Cunningham, F.6
  • 38
    • 79955159657 scopus 로고    scopus 로고
    • cited 19 Sep 2013. Available from
    • US FDA. Information for healthcare professionals: conventional antipsychotics. 2008 (cited 19 Sep 2013). Available from: http://www.fda.gov/ Drugs/DrugSafety/PostmarketDrugSafetyInformationforPatientsandProviders/ ucm124830.htm.
    • (2008) Information for Healthcare Professionals: Conventional Antipsychotics
  • 39
    • 38449111254 scopus 로고    scopus 로고
    • Antipsychotic medication dispensing and risk of death in veterans and war widows 65 years and older
    • Hollis J, Grayson D, Forrester L, Brodaty H, Touyz S, Cumming R. Antipsychotic medication dispensing and risk of death in veterans and war widows 65 years and older. Am J Geriatr Psychiatry. 2007;15(11):932-41.
    • (2007) Am J Geriatr Psychiatry , vol.15 , Issue.11 , pp. 932-941
    • Hollis, J.1    Grayson, D.2    Forrester, L.3    Brodaty, H.4    Touyz, S.5    Cumming, R.6
  • 41
    • 84858419468 scopus 로고    scopus 로고
    • Differential risk of death in older residents in nursing homes prescribed specific antipsychotic drugs: Population based cohort study
    • Huybrechts KF, Gerhard T, Crystal S, Olfson M, Avorn J, Levin R, et al. Differential risk of death in older residents in nursing homes prescribed specific antipsychotic drugs: population based cohort study. BMJ. 2012;344:e977.
    • (2012) BMJ , vol.344
    • Huybrechts, K.F.1    Gerhard, T.2    Crystal, S.3    Olfson, M.4    Avorn, J.5    Levin, R.6
  • 43
    • 84922464822 scopus 로고    scopus 로고
    • Associations between risk of mortality and atypical antipsychotic use in vascular dementia: A clinical cohort study
    • Epub 14 Mar
    • Sultana J, Chang CK, Hayes RD, Broadbent M, Stewart R, Corbett A, et al. Associations between risk of mortality and atypical antipsychotic use in vascular dementia: a clinical cohort study. Int J Geriat Psychiatry. Epub 14 Mar 2014.
    • (2014) Int J Geriat Psychiatry
    • Sultana, J.1    Chang, C.K.2    Hayes, R.D.3    Broadbent, M.4    Stewart, R.5    Corbett, A.6
  • 44
    • 72849130317 scopus 로고    scopus 로고
    • All-cause mortality associated with atypical and conventional antipsychotics among nursing home residents with dementia: A retrospective cohort study
    • Liperoti R, Onder G, Landi F, Lapane KL, Mor V, Bernabei R, et al. All-cause mortality associated with atypical and conventional antipsychotics among nursing home residents with dementia: a retrospective cohort study. J Clin Psychiatry. 2009;70(10):1340-7.
    • (2009) J Clin Psychiatry , vol.70 , Issue.10 , pp. 1340-1347
    • Liperoti, R.1    Onder, G.2    Landi, F.3    Lapane, K.L.4    Mor, V.5    Bernabei, R.6
  • 46
    • 79955125975 scopus 로고    scopus 로고
    • Risk of death and hospital admission for major medical events after initiation of psychotropic medications in older adults admitted to nursing homes
    • Huybrechts KF, Rothman KJ, Silliman RA, Brookhart MA, Schneeweiss S. Risk of death and hospital admission for major medical events after initiation of psychotropic medications in older adults admitted to nursing homes. CMAJ. 2011;183(7):E411-9.
    • (2011) CMAJ , vol.183 , Issue.7
    • Huybrechts, K.F.1    Rothman, K.J.2    Silliman, R.A.3    Brookhart, M.A.4    Schneeweiss, S.5
  • 47
    • 25844488136 scopus 로고    scopus 로고
    • Management of agitation, aggression, and psychosis associated with dementia: A pooled analysis including three randomized, placebo-controlled double-blind trials in nursing home residents treated with risperidone
    • DOI 10.1016/j.clineuro.2005.03.013, PII S0303846705000764
    • De Deyn PP, Katz IR, Brodaty H, Lyons B, Greenspan A, Burns A. Management of agitation, aggression, and psychosis associated with dementia: a pooled analysis including three randomized, placebo-controlled double-blind trials in nursing home residents treated with risperidone. Clin Neurol Neurosurg. 2005;107(6):497-508. (Pubitemid 41395226)
    • (2005) Clinical Neurology and Neurosurgery , vol.107 , Issue.6 , pp. 497-508
    • De Deyn, P.P.1    Katz, I.R.2    Brodaty, H.3    Lyons, B.4    Greenspan, A.5    Burns, A.6
  • 49
    • 84867736285 scopus 로고    scopus 로고
    • Risk of death in dual-eligible nursing home residents using typical or atypical antipsychotic agents
    • Aparasu RR, Chatterjee S, Mehta S, Chen H. Risk of death in dual-eligible nursing home residents using typical or atypical antipsychotic agents. Med Care. 2012;50(11):961-9.
    • (2012) Med Care , vol.50 , Issue.11 , pp. 961-969
    • Aparasu, R.R.1    Chatterjee, S.2    Mehta, S.3    Chen, H.4
  • 50
    • 51249092361 scopus 로고    scopus 로고
    • Potential causes of higher mortality in elderly users of conventional and atypical antipsychotic medications
    • Setoguchi S, Wang PS, Alan Brookhart M, Canning CF, Kaci L, Schneeweiss S. Potential causes of higher mortality in elderly users of conventional and atypical antipsychotic medications. J Am Geriatr Soc. 2008;56(9):1644-50.
    • (2008) J Am Geriatr Soc , vol.56 , Issue.9 , pp. 1644-1650
    • Setoguchi, S.1    Wang, P.S.2    Alan Brookhart, M.3    Canning, C.F.4    Kaci, L.5    Schneeweiss, S.6
  • 51
    • 34447135513 scopus 로고    scopus 로고
    • Neither atypical nor conventional antipsychotics increase mortality or hospital admissions among elderly patients with dementia: A two-year prospective study
    • Raivio MM, Laurila JV, Strandberg TE, Tilvis RS, Pitkala KH. Neither atypical nor conventional antipsychotics increase mortality or hospital admissions among elderly patients with dementia: a two-year prospective study. Am J Geriatr Psychiatry. 2007;15(5):416-24.
    • (2007) Am J Geriatr Psychiatry , vol.15 , Issue.5 , pp. 416-424
    • Raivio, M.M.1    Laurila, J.V.2    Strandberg, T.E.3    Tilvis, R.S.4    Pitkala, K.H.5
  • 52
    • 17844363843 scopus 로고    scopus 로고
    • Effect of antipsychotics on mortality in elderly patients with dementia: A 1-year prospective study in a nursing home
    • DOI 10.1017/S1041610205002243, PII S1041610205002243
    • Suh GH, Shah A. Effect of antipsychotics on mortality in elderly patients with dementia: a 1-year prospective study in a nursing home. Int Psychogeriatr. 2005;17(3):429-41. (Pubitemid 41391687)
    • (2005) International Psychogeriatrics , vol.17 , Issue.3 , pp. 429-441
    • Suh, G.-H.1    Shah, A.2
  • 54
    • 27144492767 scopus 로고    scopus 로고
    • Committee on Safety of Medicines. Cited 15 May 14. Available from
    • Committee on Safety of Medicines. Latest news: atypical antipsychotic drugs and stroke. 2004 (Cited 15 May 14). Available from: http://www.mhra.gov. uk/Safetyinformation/Safetywarningsalertsandrecalls/ Safetywarningsandmessagesformedicines/CON1004298.
    • (2004) Latest News: Atypical Antipsychotic Drugs and Stroke
  • 55
    • 84904755677 scopus 로고    scopus 로고
    • Italian Drug Agency Abilify (aripiprazolo). Cited 15 May 14. Accessed from
    • Italian Drug Agency.Nota informativa importante concordata conle autorità regolatorie europee e l'AIFA. Abilify (aripiprazolo). 2005 (Cited 15 May 14). Accessed from: http://www.agenziafarmaco.gov.it/wscs-render- attachment-by-id/111.42951.11587699323687791.pdf?id=111.98244.1138874026036.
    • (2005) Nota Informativa Importante Concordata Conle Autorità Regolatorie Europee e L'AIFA
  • 56
    • 2942618528 scopus 로고    scopus 로고
    • Atypical antipsychotics and risk of cerebrovascular accidents
    • DOI 10.1176/appi.ajp.161.6.1113
    • Herrmann N, Mamdani M, Lanctot KL. Atypical antipsychotics and risk of cerebrovascular accidents. Am J Psychiatry. 2004;161(6):1113-5. (Pubitemid 38736000)
    • (2004) American Journal of Psychiatry , vol.161 , Issue.6 , pp. 1113-1115
    • Herrmann, N.1    Mamdani, M.2    Lanctot, K.L.3
  • 57
    • 28744446448 scopus 로고    scopus 로고
    • Risperidone treatment in elderly patients with dementia: Relative risk of cerebrovascular events versus other antipsychotics
    • DOI 10.1017/S1041610205002280
    • Finkel S, Kozma C, Long S, Greenspan A, Mahmoud R, Baser O, et al. Risperidone treatment in elderly patients with dementia: relative risk of cerebrovascular events versus other antipsychotics. Int Psychogeriatr. 2005;17(4):617-29. (Pubitemid 41758766)
    • (2005) International Psychogeriatrics , vol.17 , Issue.4 , pp. 617-629
    • Finkel, S.1    Kozma, C.2    Long, S.3    Greenspan, A.4    Mahmoud, R.5    Baser, O.6    Engelhart, L.7
  • 58
    • 25444456717 scopus 로고    scopus 로고
    • Second-generation antipsychotics and risk of cerebrovascular accidents in the elderly
    • DOI 10.1097/01.jcp.0000178414.14685.c4
    • Percudani M, Barbui C, Fortino I, Tansella M, Petrovich L. Second-generation antipsychotics and risk of cerebrovascular accidents in the elderly. J Clin Psychopharmacol. 2005;25(5):468-70. (Pubitemid 41368370)
    • (2005) Journal of Clinical Psychopharmacology , vol.25 , Issue.5 , pp. 468-470
    • Percudani, M.1    Barbui, C.2    Fortino, I.3    Tansella, M.4    Petrovich, L.5
  • 59
    • 39649086952 scopus 로고    scopus 로고
    • Comparison of risk of cerebrovascular events in an elderly VA population with dementia between antipsychotic and nonantipsychotic users
    • DOI 10.1097/jcp.0b013e31815a2531, PII 0000471420071200000007
    • Barnett MJ, Wehring H, Perry PJ. Comparison of risk of cerebrovascular events in an elderly VA population with dementia between antipsychotic and nonantipsychotic users. J Clin Psychopharmacol. 2007;27(6):595-601. (Pubitemid 351339446)
    • (2007) Journal of Clinical Psychopharmacology , vol.27 , Issue.6 , pp. 595-601
    • Barnett, M.J.1    Wehring, H.2    Perry, P.J.3
  • 60
    • 37749013455 scopus 로고    scopus 로고
    • Risk of stroke with typical and atypical anti-psychotics: A retrospective cohort study including unexposed subjects
    • Sacchetti E, Trifiro G, Caputi A, Turrina C, Spina E, Cricelli C, et al. Risk of stroke with typical and atypical anti-psychotics: a retrospective cohort study including unexposed subjects. J Psychopharmacol. 2008;22(1):39-46.
    • (2008) J Psychopharmacol , vol.22 , Issue.1 , pp. 39-46
    • Sacchetti, E.1    Trifiro, G.2    Caputi, A.3    Turrina, C.4    Spina, E.5    Cricelli, C.6
  • 61
    • 25844449630 scopus 로고    scopus 로고
    • Comparison of incidence rates of cerebrovascular accidents and transient ischaemic attacks in observational cohort studies of patients prescribed risperidone, quetiapine or olanzapine in general practice in England including patients with dementia
    • DOI 10.1177/0269881105056524
    • Layton D, Harris S, Wilton LV, Shakir SA. Comparison of incidence rates of cerebrovascular accidents and transient ischaemic attacks in observational cohort studies of patients prescribed risperidone, quetiapine or olanzapine in general practice in England including patients with dementia. J Psychopharmacol. 2005;19(5):473-82. (Pubitemid 41392301)
    • (2005) Journal of Psychopharmacology , vol.19 , Issue.5 , pp. 473-482
    • Layton, D.1    Harris, S.2    Wilton, L.V.3    Shakir, S.A.W.4
  • 62
    • 20044375721 scopus 로고    scopus 로고
    • Atypical antipsychotic drugs and risk of ischaemic stroke: Population based retrospective cohort study
    • Gill SS, Rochon PA, Herrmann N, Lee PE, Sykora K, Gunraj N, et al. Atypical antipsychotic drugs and risk of ischaemic stroke: population based retrospective cohort study. BMJ. 2005;330(7489):445.
    • (2005) BMJ , vol.330 , Issue.7489 , pp. 445
    • Gill, S.S.1    Rochon, P.A.2    Herrmann, N.3    Lee, P.E.4    Sykora, K.5    Gunraj, N.6
  • 64
    • 2342628427 scopus 로고    scopus 로고
    • Olanzapine (Zyprexa): Increased incidence of cerebrovascular events in dementia trials
    • DOI 10.1503/cmaj.1040539
    • Wooltorton E. Olanzapine (Zyprexa): increased incidence of cerebrovascular events in dementia trials. CMAJ. 2004;170(9):1395. (Pubitemid 38594631)
    • (2004) Canadian Medical Association Journal , vol.170 , Issue.9 , pp. 1395
    • Wooltorton, E.1
  • 65
    • 51949116347 scopus 로고    scopus 로고
    • Exposure to antipsychotics and risk of stroke: Self controlled case series study
    • Douglas IJ, Smeeth L. Exposure to antipsychotics and risk of stroke: self controlled case series study. BMJ. 2008;337:a1227.
    • (2008) BMJ , vol.337
    • Douglas, I.J.1    Smeeth, L.2
  • 66
    • 84873716475 scopus 로고    scopus 로고
    • Association of stroke with the receptor-binding profiles of antipsychotics: A case-crossover study
    • Wu CS, Wang SC, Gau SS, Tsai HJ, Cheng YC. Association of stroke with the receptor-binding profiles of antipsychotics: a case-crossover study. Biol Psychiatry. 2013;73(5):414-21.
    • (2013) Biol Psychiatry , vol.73 , Issue.5 , pp. 414-421
    • Wu, C.S.1    Wang, S.C.2    Gau, S.S.3    Tsai, H.J.4    Cheng, Y.C.5
  • 69
    • 79960426655 scopus 로고    scopus 로고
    • Risk of cerebrovascular accident associated with use of antipsychotics: Population-based case-control study
    • Laredo L, Vargas E, Blasco AJ, Aguilar MD, Moreno A, Portoles A. Risk of cerebrovascular accident associated with use of antipsychotics: population-based case-control study. J Am Geriatr Soc. 2011;59(7):1182-7.
    • (2011) J Am Geriatr Soc , vol.59 , Issue.7 , pp. 1182-1187
    • Laredo, L.1    Vargas, E.2    Blasco, A.J.3    Aguilar, M.D.4    Moreno, A.5    Portoles, A.6
  • 70
    • 84855356825 scopus 로고    scopus 로고
    • Age, antipsychotics, and the risk of ischemic stroke in the Veterans Health Administration
    • Wang S, Linkletter C, Dore D, Mor V, Buka S, Maclure M. Age, antipsychotics, and the risk of ischemic stroke in the Veterans Health Administration. Stroke. 2013;43(1):28-31.
    • (2013) Stroke , vol.43 , Issue.1 , pp. 28-31
    • Wang, S.1    Linkletter, C.2    Dore, D.3    Mor, V.4    Buka, S.5    Maclure, M.6
  • 71
    • 77949530870 scopus 로고    scopus 로고
    • Antipsychotics and risk of cerebrovascular events in treatment of behavioural and psychological symptoms of dementia in Hong Kong: A hospital-based, retrospective, cohort study
    • Chan MC, Chong CS, Wu AY, Wong KC, Dunn EL, Tang OW, et al. Antipsychotics and risk of cerebrovascular events in treatment of behavioural and psychological symptoms of dementia in Hong Kong: a hospital-based, retrospective, cohort study. Int J Geriat Psychiatry. 2010;25(4):362-70.
    • (2010) Int J Geriat Psychiatry , vol.25 , Issue.4 , pp. 362-370
    • Chan, M.C.1    Chong, C.S.2    Wu, A.Y.3    Wong, K.C.4    Dunn, E.L.5    Tang, O.W.6
  • 73
    • 14644396191 scopus 로고    scopus 로고
    • Do atypical antipsychotics cause stroke?
    • DOI 10.2165/00023210-200519020-00001
    • Herrmann N, Lanctot KL. Do atypical antipsychotics cause stroke? CNS Drugs. 2005;19(2):91-103. (Pubitemid 40321762)
    • (2005) CNS Drugs , vol.19 , Issue.2 , pp. 91-103
    • Herrmann, N.1    Lanctot, K.L.2
  • 74
    • 1642408640 scopus 로고    scopus 로고
    • Association between risperidone treatment and cerebrovascular adverse events: Examining the evidence and postulating hypotheses for an underlying mechanism
    • Smith DA, Beier MT. Association between risperidone treatment and cerebrovascular adverse events: examining the evidence and postulating hypotheses for an underlying mechanism. J Am Med Dir Assoc. 2004;5(2):129-32. (Pubitemid 38380415)
    • (2004) Journal of the American Medical Directors Association , vol.5 , Issue.2 , pp. 129-132
    • Smith, D.A.1    Beier, M.T.2
  • 77
    • 77951250998 scopus 로고    scopus 로고
    • Association of community-acquired pneumonia with antipsychotic drug use in elderly patients: A nested case-control study
    • Trifiro G, Gambassi G, Sen EF, Caputi AP, Bagnardi V, Brea J, et al. Association of community-acquired pneumonia with antipsychotic drug use in elderly patients: a nested case-control study. Ann Intern Med. 2010;152(7):418-25, W139-40.
    • (2010) Ann Intern Med , vol.152 , Issue.7
    • Trifiro, G.1    Gambassi, G.2    Sen, E.F.3    Caputi, A.P.4    Bagnardi, V.5    Brea, J.6
  • 78
    • 79956196565 scopus 로고    scopus 로고
    • Antipsychotic drug use and community-acquired pneumonia
    • Trifiro G. Antipsychotic drug use and community-acquired pneumonia. Curr Infect Dis Rep. 2011;13(3):262-8.
    • (2011) Curr Infect Dis Rep , vol.13 , Issue.3 , pp. 262-268
    • Trifiro, G.1
  • 80
    • 0034712552 scopus 로고    scopus 로고
    • QTc-interval abnormalities and psychotropic drug therapy in psychiatric patients
    • Reilly JG, Ayis SA, Ferrier IN, Jones SJ, Thomas SH. QTc-interval abnormalities and psychotropic drug therapy in psychiatric patients. Lancet. 2000;355(9209):1048-52. (Pubitemid 30162807)
    • (2000) Lancet , vol.355 , Issue.9209 , pp. 1048-1052
    • Reilly, J.G.1    Ayis, S.A.2    Ferrier, I.N.3    Jones, S.J.4    Thomas, S.H.L.5
  • 81
    • 79958226940 scopus 로고    scopus 로고
    • Assessing QT interval prolongation and its associated risks with antipsychotics
    • Nielsen J, Graff C, Kanters JK, Toft E, Taylor D, Meyer JM. Assessing QT interval prolongation and its associated risks with antipsychotics. CNS Drugs. 2011;25(6):473-90.
    • (2011) CNS Drugs , vol.25 , Issue.6 , pp. 473-490
    • Nielsen, J.1    Graff, C.2    Kanters, J.K.3    Toft, E.4    Taylor, D.5    Meyer, J.M.6
  • 83
    • 0037048987 scopus 로고    scopus 로고
    • Cardiac arrest and ventricular arrhythmia in patients taking antipsychotic drugs: Cohort study using administrative data
    • Hennessy S, Bilker WB, Knauss JS, Margolis DJ, Kimmel SE, Reynolds RF, et al. Cardiac arrest and ventricular arrhythmia in patients taking antipsychotic drugs: cohort study using administrative data. BMJ. 2002;325(7372):1070.
    • (2002) BMJ , vol.325 , Issue.7372 , pp. 1070
    • Hennessy, S.1    Bilker, W.B.2    Knauss, J.S.3    Margolis, D.J.4    Kimmel, S.E.5    Reynolds, R.F.6
  • 84
    • 58349114259 scopus 로고    scopus 로고
    • Atypical antipsychotic drugs and the risk of sudden cardiac death
    • Ray WA, Chung CP, Murray KT, Hall K, Stein CM. Atypical antipsychotic drugs and the risk of sudden cardiac death. N Engl J Med. 2009;360(3):225-35.
    • (2009) N Engl J Med , vol.360 , Issue.3 , pp. 225-235
    • Ray, W.A.1    Chung, C.P.2    Murray, K.T.3    Hall, K.4    Stein, C.M.5
  • 86
    • 84865835392 scopus 로고    scopus 로고
    • Atypical antipsychotic use in patients with dementia: Managing safety concerns
    • Steinberg M, Lyketsos CG. Atypical antipsychotic use in patients with dementia: managing safety concerns. Am J Psychiatry. 2012;169(9):900-6.
    • (2012) Am J Psychiatry , vol.169 , Issue.9 , pp. 900-906
    • Steinberg, M.1    Lyketsos, C.G.2
  • 89
    • 0034619072 scopus 로고    scopus 로고
    • Antipsychotic drug use and risk of first-time idiopathic venous thromboembolism: A case-control study
    • Zornberg GL, Jick H. Antipsychotic drug use and risk of first-time idiopathic venous thromboembolism: a case-control study. Lancet. 2000;356(9237):1219-23.
    • (2000) Lancet , vol.356 , Issue.9237 , pp. 1219-1223
    • Zornberg, G.L.1    Jick, H.2
  • 90
    • 0035798942 scopus 로고    scopus 로고
    • Antipsychotic drugs and venous thromboembolism
    • author reply, 2
    • Tipper R, Hare E, Kondracki S, Taikato M, Lawrie SM. Antipsychotic drugs and venous thromboembolism. Lancet. 2001;357(9253):391;author reply, 2.
    • (2001) Lancet , vol.357 , Issue.9253 , pp. 391
    • Tipper, R.1    Hare, E.2    Kondracki, S.3    Taikato, M.4    Lawrie, S.M.5
  • 91
    • 0034660767 scopus 로고    scopus 로고
    • Antipsychotic drugs and venous thromboembolism
    • Thomassen R, Vandenbroucke JP, Rosendaal FR. Antipsychotic drugs and venous thromboembolism. Lancet. 2000;356(9225):252.
    • (2000) Lancet , vol.356 , Issue.9225 , pp. 252
    • Thomassen, R.1    Vandenbroucke, J.P.2    Rosendaal, F.R.3
  • 92
    • 0036339345 scopus 로고    scopus 로고
    • Antipsychotic and antidepressant drug use in the elderly and the risk of venous thromboembolism
    • Ray J, Mamdani M, Yeo E. Antipsychotic and antidepressant drug use in the elderly and the risk of venous thromboembolism. Thromb Haemost. 2002;88(2):205-9. (Pubitemid 34873699)
    • (2002) Thrombosis and Haemostasis , vol.88 , Issue.2 , pp. 205-209
    • Ray, J.G.1    Mamdani, M.M.2    Yeo, E.L.3
  • 94
    • 0037245162 scopus 로고    scopus 로고
    • Acute massive pulmonary thromboembolism associated with risperidone and conventional phenothiazines
    • DOI 10.1253/circj.67.46
    • Kamijo Y, Soma K, Nagai T, Kurihara K, Ohwada T. Acute massive pulmonary thromboembolism associated with risperidone and conventional phenothiazines. Circ J. 2003;67(1):46-8. (Pubitemid 36119621)
    • (2003) Circulation Journal , vol.67 , Issue.1 , pp. 46-48
    • Kamijo, Y.1    Soma, K.2    Nagai, T.3    Kurihara, K.4    Ohwada, T.5
  • 95
    • 4544272257 scopus 로고    scopus 로고
    • Massive pulmonary thromboembolism demonstrated at necropsy in Japanese psychiatric patients treated with neuroleptics including atypical antipsychotics
    • DOI 10.1253/circj.68.850
    • Hamanaka S, Kamijo Y, Nagai T, Kurihara K, Tanaka K, Soma K, et al. Massive pulmonary thromboembolism demonstrated at necropsy in Japanese psychiatric patients treated with neuroleptics including atypical antipsychotics. Circ J. 2004;68(9):850-2. (Pubitemid 39243806)
    • (2004) Circulation Journal , vol.68 , Issue.9 , pp. 850-852
    • Hamanaka, S.1    Kamijo, Y.2    Nagai, T.3    Kurihara, K.4    Tanaka, K.5    Soma, K.6    Miyaoka, H.7
  • 96
    • 28944441100 scopus 로고    scopus 로고
    • Venous thromboembolism among elderly patients treated with atypical and conventional antipsychotic agents
    • DOI 10.1001/archinte.165.22.2677
    • Liperoti R, Pedone C, Lapane KL, Mor V, Bernabei R, Gambassi G. Venous thromboembolism among elderly patients treated with atypical and conventional antipsychotic agents. Arch Intern Med. 2005;165(22):2677-82. (Pubitemid 41785068)
    • (2005) Archives of Internal Medicine , vol.165 , Issue.22 , pp. 2677-2682
    • Liperoti, R.1    Pedone, C.2    Lapane, K.L.3    Mor, V.4    Bernabei, R.5    Gambassi, G.6
  • 97
    • 36349004648 scopus 로고    scopus 로고
    • Association between antipsychotic drugs, antidepressant drugs and venous thromboembolism: Results from the EDITH case-control study
    • DOI 10.1111/j.1472-8206.2007.00515.x
    • Lacut K, Le Gal G, Couturaud F, Cornily G, Leroyer C, Mottier D, et al. Association between antipsychotic drugs, antidepressant drugs and venous thromboembolism: results from the EDITH case-control study. Fundam Clin Pharmacol. 2007;21(6):643-50. (Pubitemid 350151244)
    • (2007) Fundamental and Clinical Pharmacology , vol.21 , Issue.6 , pp. 643-650
    • Lacut, K.1    Le, G.G.2    Couturaud, F.3    Cornily, G.4    Leroyer, C.5    Mottier, D.6    Oger, E.7
  • 98
    • 47649124634 scopus 로고    scopus 로고
    • Associations between venous thromboembolism and antipsychotics: A study of the WHO database of adverse drug reactions
    • DOI 10.2165/00002018-200831080-00005
    • Hagg S, Bate A, Stahl M, Spigset O. Associations between venous thromboembolism and antipsychotics. A study of the WHO database of adverse drug reactions. Drug Saf. 2008;31(8):685-94. (Pubitemid 352019566)
    • (2008) Drug Safety , vol.31 , Issue.8 , pp. 685-694
    • Hagg, S.1    Bate, A.2    Stahl, M.3    Spigset, O.4
  • 100
    • 77957171407 scopus 로고    scopus 로고
    • Antipsychotic drugs and risk of venous thromboembolism: Nested case-control study
    • Parker C, Coupland C, Hippisley-Cox J. Antipsychotic drugs and risk of venous thromboembolism: nested case-control study. BMJ. 2010;341:c4245.
    • (2010) BMJ , vol.341
    • Parker, C.1    Coupland, C.2    Hippisley-Cox, J.3
  • 101
    • 84888134822 scopus 로고    scopus 로고
    • Antipsychotic drug use and the risk of venous thromboembolism in elderly patients with dementia
    • Schmedt N, Garbe E. Antipsychotic drug use and the risk of venous thromboembolism in elderly patients with dementia. J Clin Psychopharmacol. 2013;33(6):753-8.
    • (2013) J Clin Psychopharmacol , vol.33 , Issue.6 , pp. 753-758
    • Schmedt, N.1    Garbe, E.2
  • 102
    • 84861515314 scopus 로고    scopus 로고
    • Atypical antipsychotic drugs, schizophrenia, and metabolic syndrome in non-Euro-American societies
    • Bou Khalil R. Atypical antipsychotic drugs, schizophrenia, and metabolic syndrome in non-Euro-American societies. Clin Neuropharmacol. 2012;35(3):141-7.
    • (2012) Clin Neuropharmacol , vol.35 , Issue.3 , pp. 141-147
    • Bou Khalil, R.1
  • 103
    • 18744366088 scopus 로고    scopus 로고
    • Second-generation (atypical) antipsychotics and metabolic effects: A comprehensive literature review
    • DOI 10.2165/00023210-200519010-00001
    • Newcomer JW. Second-generation (atypical) antipsychotics and metabolic effects: a comprehensive literature review. CNS Drugs. 2005;19(Suppl 1):1-93. (Pubitemid 40677047)
    • (2005) CNS Drugs , vol.19 , Issue.SUPPL. 1 , pp. 1-93
    • Newcomer, J.W.1
  • 104
    • 33745677489 scopus 로고    scopus 로고
    • No effect of atypical antipsychotic drugs on weight gain and risk of developing type II diabetes or lipid abnormalities among nursing home elderly patients with Alzheimer's disease
    • Rondanelli M, Sarra S, Antoniello N, Mansi S, Govoni S, Falfo F. No effect of atypical antipsychotic drugs on weight gain and risk of developing type II diabetes or lipid abnormalities among nursing home elderly patients with Alzheimer's disease. Minerva Med. 2006;97:147-51. (Pubitemid 43966273)
    • (2006) Minerva Medica , vol.97 , Issue.2 , pp. 147-151
    • Rondanelli, M.1    Sarra, S.2    Antoniello, N.3    Mansi, V.4    Govoni, S.5    Falvo, F.6    Solerte, S.B.7    Ferrari, E.8
  • 105
    • 66149171513 scopus 로고    scopus 로고
    • Metabolic changes associated with second-generation antipsychotic use in Alzheimer's disease patients: The CATIE-AD study
    • Zheng L, Mack WJ, Dagerman KS, Hsiao JK, Lebowitz BD, Lyketsos CG, et al. Metabolic changes associated with second-generation antipsychotic use in Alzheimer's disease patients: the CATIE-AD study. Am J Psychiatry. 2009;166(5):583-90.
    • (2009) Am J Psychiatry , vol.166 , Issue.5 , pp. 583-590
    • Zheng, L.1    Mack, W.J.2    Dagerman, K.S.3    Hsiao, J.K.4    Lebowitz, B.D.5    Lyketsos, C.G.6
  • 107
    • 84895075496 scopus 로고    scopus 로고
    • Predictors of mortality in atypical antipsy-chotic-treated community-dwelling elderly patients with behavioural and psychological symptoms of dementia: A prospective population-based cohort study from Italy
    • Rafaniello C, Lombardo F, Ferrajolo C, Sportiello L, Parretta E, Formica R, et al. Predictors of mortality in atypical antipsy-chotic-treated community-dwelling elderly patients with behavioural and psychological symptoms of dementia: a prospective population-based cohort study from Italy. Eur J Clin Pharmacol. 2014;70(2):187-95.
    • (2014) Eur J Clin Pharmacol , vol.70 , Issue.2 , pp. 187-195
    • Rafaniello, C.1    Lombardo, F.2    Ferrajolo, C.3    Sportiello, L.4    Parretta, E.5    Formica, R.6
  • 108
    • 79551647270 scopus 로고    scopus 로고
    • Risk of cerebrovascular adverse events and death in elderly patients with dementia when treated with antipsychotic medications: A literature review of evidence
    • Mittal V, Kurup L, Williamson D, Muralee S, Tampi RR. Risk of cerebrovascular adverse events and death in elderly patients with dementia when treated with antipsychotic medications: a literature review of evidence. Am J Alzheimers Dis Other Demen. 2011;26(1):10-28.
    • (2011) Am J Alzheimers Dis Other Demen , vol.26 , Issue.1 , pp. 10-28
    • Mittal, V.1    Kurup, L.2    Williamson, D.3    Muralee, S.4    Tampi, R.R.5
  • 110
    • 84879364740 scopus 로고    scopus 로고
    • Risk of ischemic stroke with the use of risperidone, quetiapine and olanzapine in elderly patients: A population-based, case-crossover study
    • Shin JY, Choi NK, Jung SY, Lee J, Kwon JS, Park BJ. Risk of ischemic stroke with the use of risperidone, quetiapine and olanzapine in elderly patients: a population-based, case-crossover study. J Psychopharmacol. 2013;27(7):638-44.
    • (2013) J Psychopharmacol , vol.27 , Issue.7 , pp. 638-644
    • Shin, J.Y.1    Choi, N.K.2    Jung, S.Y.3    Lee, J.4    Kwon, J.S.5    Park, B.J.6
  • 111
    • 84893931911 scopus 로고    scopus 로고
    • Antipsychotics for delirium in the general hospital setting in consecutive 2453 inpatients: A prospective observational study
    • Hatta K, Kishi Y, Wada K, Odawara T, Takeuchi T, Shiganami T, et al. Antipsychotics for delirium in the general hospital setting in consecutive 2453 inpatients: a prospective observational study. Int J Geriat Psychiatry. 2013.
    • (2013) Int J Geriat Psychiatry
    • Hatta, K.1    Kishi, Y.2    Wada, K.3    Odawara, T.4    Takeuchi, T.5    Shiganami, T.6
  • 112
    • 34347361465 scopus 로고    scopus 로고
    • Conventional or atypical antipsychotics and the risk of femur fracture among elderly patients: Results of a case-control study
    • Liperoti R, Onder G, Lapane KL, Mor V, Friedman JH, Bernabei R, et al. Conventional or atypical antipsychotics and the risk of femur fracture among elderly patients: results of a case-control study. J Clin Psychiatry. 2007;68(6):929-34. (Pubitemid 47015494)
    • (2007) Journal of Clinical Psychiatry , vol.68 , Issue.6 , pp. 929-934
    • Liperoti, R.1    Onder, G.2    Lapane, K.L.3    Mor, V.4    Friedman, J.H.5    Bernabei, R.6    Gambassi, G.7
  • 113
    • 67649194773 scopus 로고    scopus 로고
    • Antipsychotic use and the risk of hip/femur fracture: A population-based case-control study
    • Pouwels S, van Staa TP, Egberts AC, Leufkens HG, Cooper C, de Vries F. Antipsychotic use and the risk of hip/femur fracture: a population-based case-control study. Osteoporos Int. 2009;20(9):1499-506.
    • (2009) Osteoporos Int , vol.20 , Issue.9 , pp. 1499-1506
    • Pouwels, S.1    Van Staa, T.P.2    Egberts, A.C.3    Leufkens, H.G.4    Cooper, C.5    De Vries, F.6
  • 114
    • 20244384575 scopus 로고    scopus 로고
    • Quetiapine and rivastigmine and cognitive decline in Alzheimer's disease: Randomised double blind placebo controlled trial
    • Ballard C, Margallo-Lana M, Juszczak E, Douglas S, Swann A, Thomas A, et al. Quetiapine and rivastigmine and cognitive decline in Alzheimer's disease: randomised double blind placebo controlled trial. BMJ. 2005;330(7496):874.
    • (2005) BMJ , vol.330 , Issue.7496 , pp. 874
    • Ballard, C.1    Margallo-Lana, M.2    Juszczak, E.3    Douglas, S.4    Swann, A.5    Thomas, A.6
  • 115
    • 33744495314 scopus 로고    scopus 로고
    • Sensitivity analysis and external adjustment for unmeasured confounders in epidemiologic database studies of therapeutics
    • DOI 10.1002/pds.1200
    • Schneeweiss S. Sensitivity analysis and external adjustment for unmeasured confounders in epidemiologic database studies of therapeutics. Pharmacoepidemiol Drug Saf. 2006;15(5):291-303. (Pubitemid 43797117)
    • (2006) Pharmacoepidemiology and Drug Safety , vol.15 , Issue.5 , pp. 291-303
    • Schneeweiss, S.1
  • 116
    • 67651042983 scopus 로고    scopus 로고
    • High-dimensional propensity score adjustment in studies of treatment effects using health care claims data
    • Schneeweiss S, Rassen JA, Glynn RJ, Avorn J, Mogun H, Brookhart MA. High-dimensional propensity score adjustment in studies of treatment effects using health care claims data. Epidemiology. 2009;20(4):512-22.
    • (2009) Epidemiology , vol.20 , Issue.4 , pp. 512-522
    • Schneeweiss, S.1    Rassen, J.A.2    Glynn, R.J.3    Avorn, J.4    Mogun, H.5    Brookhart, M.A.6
  • 117
    • 13744260134 scopus 로고    scopus 로고
    • Adjusting for unmeasured confounders in pharmacoepidemiologic claims data using external information: The example of COX2 inhibitors and myocardial infarction
    • DOI 10.1097/01.ede.0000147164.11879.b5
    • Schneeweiss S, Glynn R, Tsai E, Avorn J, Solomon D. Assessment of bias by unmeasured confounders in pharmacoepidemiologic claims data studies using external data. Epidemiology. 2005;16:17-24. (Pubitemid 40239274)
    • (2005) Epidemiology , vol.16 , Issue.1 , pp. 17-24
    • Schneeweiss, S.1    Glynn, R.J.2    Tsai, E.H.3    Avorn, J.4    Solomon, D.H.5
  • 119
    • 79953688283 scopus 로고    scopus 로고
    • Association between prescription of conventional or atypical antipsychotic drugs and mortality in older persons with Alzheimer's disease
    • Musicco M, Palmer K, Russo A, Caltagirone C, Adorni F, Pettenati C, et al. Association between prescription of conventional or atypical antipsychotic drugs and mortality in older persons with Alzheimer's disease. Dement Geriatr Cogn Disord. 2011;31(3):218-24.
    • (2011) Dement Geriatr Cogn Disord , vol.31 , Issue.3 , pp. 218-224
    • Musicco, M.1    Palmer, K.2    Russo, A.3    Caltagirone, C.4    Adorni, F.5    Pettenati, C.6
  • 120
    • 84876552971 scopus 로고    scopus 로고
    • Population-based 5-year follow-up study in Taiwan of dementia and risk of stroke
    • Liu ME, Tsai SJ, Chang WC, Hsu CH, Lu T, Hung KS, et al. Population-based 5-year follow-up study in Taiwan of dementia and risk of stroke. PloS ONE. 2013;8(4):e61771.
    • (2013) PloS ONE , vol.8 , Issue.4
    • Liu, M.E.1    Tsai, S.J.2    Chang, W.C.3    Hsu, C.H.4    Lu, T.5    Hung, K.S.6
  • 122
    • 78650531596 scopus 로고    scopus 로고
    • Pneumonia following antipsychotic prescriptions in electronic health records: A patient safety concern?
    • Star K, Bate A, Meyboom RH, Edwards IR. Pneumonia following antipsychotic prescriptions in electronic health records: a patient safety concern? Br J Gen Pract. 2010;60(579):e385-94.
    • (2010) Br J Gen Pract , vol.60 , Issue.579
    • Star, K.1    Bate, A.2    Meyboom, R.H.3    Edwards, I.R.4
  • 123
    • 33748936850 scopus 로고    scopus 로고
    • Outcomes of Antipsychotic Drug Use in Community-Dwelling Elders With Dementia
    • DOI 10.1016/j.apnu.2006.04.004, PII S0883941706000902
    • Kolanowski A, Fick D, Waller JL, Ahern F. Outcomes of antipsychotic drug use in community-dwelling elders with dementia. Arch Psychiatr Nurs. 2006;20(5):217-25. (Pubitemid 44436834)
    • (2006) Archives of Psychiatric Nursing , vol.20 , Issue.5 , pp. 217-225
    • Kolanowski, A.1    Fick, D.2    Waller, J.L.3    Ahern, F.4
  • 124
    • 75149172347 scopus 로고    scopus 로고
    • Antipsychotic use and the risk of hip fracture among older adults afflicted with dementia
    • Jalbert JJ, Eaton CB, Miller SC, Lapane KL. Antipsychotic use and the risk of hip fracture among older adults afflicted with dementia. J Am Med Dir Assoc. 2010;11(2):120-7.
    • (2010) J Am Med Dir Assoc , vol.11 , Issue.2 , pp. 120-127
    • Jalbert, J.J.1    Eaton, C.B.2    Miller, S.C.3    Lapane, K.L.4
  • 125
    • 79958847917 scopus 로고    scopus 로고
    • Risk of hospitalization for hip fracture and pneumonia associated with antipsychotic prescribing in the elderly: A self-controlled case-series analysis in an Australian health care claims database
    • Pratt N, Roughead EE, Ramsay E, Salter A, Ryan P. Risk of hospitalization for hip fracture and pneumonia associated with antipsychotic prescribing in the elderly: a self-controlled case-series analysis in an Australian health care claims database. Drug Saf. 2011;34(7):567-75.
    • (2011) Drug Saf , vol.34 , Issue.7 , pp. 567-575
    • Pratt, N.1    Roughead, E.E.2    Ramsay, E.3    Salter, A.4    Ryan, P.5
  • 126
    • 0034965441 scopus 로고    scopus 로고
    • Hazardous benzodiazepine regimens in the elderly: Effects of half-life, dosage, and duration on risk of hip fracture
    • DOI 10.1176/appi.ajp.158.6.892
    • Wang PS, Bohn RL, Glynn RJ, Mogun H, Avorn J. Hazardous benzodiazepine regimens in the elderly: effects of half-life, dosage, and duration on risk of hip fracture. Am J Psychiatry. 2001;158(6):892-8. (Pubitemid 32547618)
    • (2001) American Journal of Psychiatry , vol.158 , Issue.6 , pp. 892-898
    • Wang, P.S.1    Bohn, R.L.2    Glynn, R.J.3    Mogun, H.4    Avorn, J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.