Antipsychotics and the risk of sudden cardiac death

Archives of Internal Medicine

Volumn 164, Issue 12, 2004, Pages 1293-1297

  Straus, Sabine M J M ^a   Bleumink, Gysèle S ^a,c   Dieleman, Jeanne P ^a   Van Der Lei, Johan ^a   'T Jong, Geert W ^a   Kingma, J Herre ^b,d   Sturkenboom, Miriam C J M ^a   Stricker, Bruno H C ^a,c  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b MEDICINES EVALUATION BOARD   (Netherlands)

^c Inspectorate for Health Care   (Netherlands)

^d UNIVERSITY OF GRONINGEN   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN 2 RECEPTOR ANTAGONIST; ANTIARRHYTHMIC AGENT; ANTILIPEMIC AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BUTYROPHENONE DERIVATIVE; CALCIUM CHANNEL BLOCKING AGENT; CARDIAC GLYCOSIDE; CARDIOVASCULAR AGENT; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; LITHIUM; NEUROLEPTIC AGENT; PHENOTHIAZINE DERIVATIVE; THIOXANTHENE DERIVATIVE;

ADULT; ALCOHOL ABUSE; ARTICLE; CARDIOVASCULAR DISEASE; CASE CONTROL STUDY; CEREBROVASCULAR DISEASE; COMORBIDITY; CONTROLLED STUDY; DIABETES MELLITUS; FEMALE; HEART ARRHYTHMIA; HEART FAILURE; HUMAN; HYPERCHOLESTEROLEMIA; HYPERTENSION; LONG TERM CARE; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD; PRIORITY JOURNAL; QT PROLONGATION; RISK FACTOR; SCHIZOPHRENIA; SMOKING; STATISTICAL ANALYSIS; SUDDEN DEATH;

ADOLESCENT; ADULT; AGED; ANTIPSYCHOTIC AGENTS; CASE-CONTROL STUDIES; DEATH, SUDDEN, CARDIAC; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HEART CONDUCTION SYSTEM; HUMANS; INCIDENCE; MALE; MIDDLE AGED; RISK FACTORS; SCHIZOPHRENIA; STATISTICS; SURVIVAL ANALYSIS; TREATMENT FAILURE;

EID: 3042542936     PISSN: 00039926     EISSN: None     Source Type: Journal    
DOI: 10.1001/archinte.164.12.1293     Document Type: Article

References (22)

1. Myerburg RJ. Cardiac arrest and sudden cardiac death. In: Braunwald E, ed. Heart Disease, A Text Book of Cardiovascular Medicine. New York, NY: WB Saunders Publishing Co; 1997:742-779.
2. Priori SG, Aliot E, Blomstrom-Lundqvist C, et al. Task Force on Sudden Cardiac Death of the European Society of Cardiology. Eur Heart J. 2001;22:1374-450.
3. Granger ME. Phenothiazines and sudden death. JAMA. 1965;194:678-679.
4. Witton K. Phenothiazines and sudden death. JAMA. 1965;194:679.
5. Huston JR, Bell GE. The effect of thioridazine hydrochloride and chlorpromazine on the electrocardiogram. JAMA. 1966;198:134-138.
6. Haddad PM, Anderson IM. Antipsychotic-related QTc prolongation, torsade de pointes and sudden death. Drugs. 2002;62:1649-1671.
7. Reilly JG, Ayis SA, Ferrier IN, Jones SJ, Thomas SH. QTc-interval abnormalities and psychotropic drug therapy in psychiatric patients. Lancet. 2000;355:1048-1052.
8. Ray WA, Meredith S, Thapa PB, Meador KG, Hall K, Murray KT. Antipsychotics and the risk of sudden cardiac death. Arch Gen Psychiatry. 2001;58:1161-1167.
9. Reilly JG, Ayis SA, Ferrier IN, Jones SJ, Thomas SH. Thioridazine and sudden unexplained death in psychiatric in-patients. Br J Psychiatry. 2002;180:515-522.
10. Hennessy S, Bilker WB, Knauss JS, et al. Cardiac arrest and ventricular arrhythmia in patients taking antipsychotic drugs: cohort study using administrative data. BMJ. 2002;325:1070.
11. Vlug AE, van der Lei J, Mosseveld BM, et al. Postmarketing surveillance based on electronic patient records: the IPCI project. Methods Inf Med. 1999;38:339-344.
12. van der Lei J, Duisterhout JS, Westerhof HP, et al. The introduction of computer-based patient records in the Netherlands. Ann Intern Med. 1993;119:1036-1041.
13. Lamberts H, Wood M, Hofmans-Okkes IM. International primary care classifications: the effect of fifteen years of evolution. Fam Pract. 1992;9:330-339.
14. ATC Index With DDDs. Oslo, Norway: WHO Collaborating Centre for Drug Statistics Methodology; 2002.
15. 1999 World Health Organization-International Society of Hypertension Guidelines for the Management of Hypertension: Guidelines Subcommittee. J Hypertens. 1999;17:151-183.
16. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition. Washington, DC: American Psychiatric Association; 1994.
17. Greenland S. Modeling and variable selection in epidemiologic analysis. Am J Public Health. 1989;79:340-349.
18. De Ponti F, Poluzzi E, Montanaro N. Organising evidence on QT prolongation and occurrence of torsades de pointes with non-antiarrhythmic drugs: a call for consensus. Eur J Clin Pharmacol 2001;57:185-209.
19. Glassman AH, Bigger JT Jr. Antipsychotic drugs: prolonged QTc interval, torsade de pointes, and sudden death. Am J Psychiatry. 2001;158:1774-1782.
20. Huikuri HV, Castellanos A, Myerburg RJ. Sudden death due to cardiac arrhythmias. N Engl J Med. 2001;345:1473-1482.
21. van Staa TP, Abenhaim L, Leufkens H. A study of the effects of exposure misclassification due to the time-window design in pharmacoepidemiologic studies. J Clin Epidemiol 1994;47:183-189.
22. de Vreede-Swagemakers JJ, Gorgels AP, Weijenberg MP, et al. Risk indicators for out-of-hospital cardiac arrest in patients with coronary artery disease. J Clin Epidemiol 1999;52:601-607.