-
1
-
-
0034792584
-
Clinical relevance of genetic polymorphisms in the human CYP2C subfamily
-
DOI 10.1046/j.0306-5251.2001.01499.x
-
J.A. Goldstein Clinical relevance of genetic polymorphisms in the human CYP2C subfamily Br J Clin Pharmacol 52 2001 349 355 (Pubitemid 32939439)
-
(2001)
British Journal of Clinical Pharmacology
, vol.52
, Issue.4
, pp. 349-355
-
-
Goldstein, J.A.1
-
2
-
-
0028590127
-
Biochemistry and molecular biology of the human CYP2C subfamily
-
J.A. Goldstein, and S.M. de Morais Biochemistry and molecular biology of the human CYP2C subfamily Pharmacogenetics 4 1994 285 299
-
(1994)
Pharmacogenetics
, vol.4
, pp. 285-299
-
-
Goldstein, J.A.1
De Morais, S.M.2
-
3
-
-
0032520750
-
Regional distribution of individual forms of cytochrome P450 mRNA in normal adult human brain
-
DOI 10.1016/S0006-2952(97)00516-9, PII S0006295297005169
-
M.C. McFayden, W.T. Melvin, and G.I. Murray Regional distribution of individual forms of cytochrome P450 mRNA in normal adult human brain Biochem Pharmacol 55 1998 825 830 (Pubitemid 28319646)
-
(1998)
Biochemical Pharmacology
, vol.55
, Issue.6
, pp. 825-830
-
-
McFadyen, M.C.E.1
Melvin, W.T.2
Murray, G.I.3
-
5
-
-
34047173527
-
Detection of human CYP2C8, CYP2C9, and CYP2J2 in cardiovascular tissues
-
DOI 10.1124/dmd.106.012823
-
T.C. Delozier, G.E. Kissling, S.J. Coulter, D. Dai, J.F. Foley, and J.A. Bradbury et al. Detection of human CYP2C8, CYP2C9, and CYP2J2 in cardiovascular tissues Drug Metab Dispos 35 2007 682 688 (Pubitemid 46513273)
-
(2007)
Drug Metabolism and Disposition
, vol.35
, Issue.4
, pp. 682-688
-
-
DeLozier, T.C.1
Kissling, G.E.2
Coulter, S.J.3
Dai, D.4
Foley, J.F.5
Bradbury, J.A.6
Murphy, E.7
Steenbergen, C.8
Zeldin, D.C.9
Goldstein, J.A.10
-
6
-
-
79551646708
-
Endothelial CYP epoxygenase overexpression and soluble epoxide hydrolase disruption attenuate acute vascular inflammatory responses in mice
-
Y. Deng, M.L. Edin, K.N. Theken, R.N. Schuck, G.P. Flake, and M.A. Kannon et al. Endothelial CYP epoxygenase overexpression and soluble epoxide hydrolase disruption attenuate acute vascular inflammatory responses in mice FASEB J 25 2011 703 713
-
(2011)
FASEB J
, vol.25
, pp. 703-713
-
-
Deng, Y.1
Edin, M.L.2
Theken, K.N.3
Schuck, R.N.4
Flake, G.P.5
Kannon, M.A.6
-
7
-
-
0037016761
-
Transcriptional regulation of CYP2C9 gene. Role of glucocorticoid receptor and constitutive androstane receptor
-
DOI 10.1074/jbc.M107228200
-
S. Gerbal-Chaloin, M. Daujat, J.M. Pascussi, L. Pichard-Garcia, M.J. Vilarem, and P. Maurel Transcriptional regulation of CYP2C9 gene. Role of glucocorticoid receptor and constitutive androstane receptor J Biol Chem 277 2002 209 217 (Pubitemid 34952047)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.1
, pp. 209-217
-
-
Gerbal-Chaloin, S.1
Daujat, M.2
Pascussi, J.-M.3
Pichard-Garcia, L.4
Vilarem, M.-J.5
Maurel, P.6
-
8
-
-
0036765751
-
Regulation of human CYP2C9 by the constitutive androstane receptor: Discovery of a new distal binding site
-
DOI 10.1124/mol.62.3.737
-
S.S. Ferguson, E.L. LeCluyse, M. Negishi, and J.A. Goldstein Regulation of human CYP2C9 by the constitutive androstane receptor: discovery of a new distal binding site Mol Pharmacol 62 2002 737 746 (Pubitemid 36329394)
-
(2002)
Molecular Pharmacology
, vol.62
, Issue.3
, pp. 737-746
-
-
Ferguson, S.S.1
Lecluyse, E.L.2
Negishi, M.3
Goldstein, J.A.4
-
9
-
-
23944516070
-
Human CYP2C8 is transcriptionally regulated by the nuclear receptors constitutive androstane receptor, pregnane X receptor, glucocorticoid receptor, and hepatic nuclear factor 4α
-
DOI 10.1124/mol.105.013169
-
S.S. Ferguson, Y. Chen, E.L. LeCluyse, M. Negishi, and J.A. Goldstein Human CYP2C8 is transcriptionally regulated by the nuclear receptors constitutive androstane receptor, pregnane X receptor, glucocorticoid receptor, and hepatic nuclear factor 4alpha Mol Pharmacol 68 2005 747 757 (Pubitemid 41206028)
-
(2005)
Molecular Pharmacology
, vol.68
, Issue.3
, pp. 747-757
-
-
Ferguson, S.S.1
Chen, Y.2
LeCluyse, E.L.3
Negishi, M.4
Goldstein, J.A.5
-
10
-
-
0042844649
-
Identification of constitutive androstane receptor and glucocorticoid receptor binding sites in the CYP2C19 promoter
-
DOI 10.1124/mol.64.2.316
-
Y. Chen, S.S. Ferguson, M. Negishi, and J.A. Goldstein Identification of constitutive androstane receptor and glucocorticoid receptor binding sites in the CYP2C19 promoter Mol Pharmacol 64 2003 316 324 (Pubitemid 36909995)
-
(2003)
Molecular Pharmacology
, vol.64
, Issue.2
, pp. 316-324
-
-
Chen, Y.1
Ferguson, S.S.2
Negishi, M.3
Goldstein, J.A.4
-
11
-
-
1642498178
-
Induction of Human CYP2C9 by Rifampicin, Hyperforin, and Phenobarbital Is Mediated by the Pregnane X Receptor
-
DOI 10.1124/jpet.103.058818
-
Y. Chen, S.S. Ferguson, M. Negishi, and J.A. Goldstein Induction of human CYP2C9 by rifampicin, hyperforin, and phenobarbital is mediated by the pregnane X receptor J Pharmacol Exp Ther 308 2004 495 501 (Pubitemid 38134210)
-
(2004)
Journal of Pharmacology and Experimental Therapeutics
, vol.308
, Issue.2
, pp. 495-501
-
-
Chen, Y.1
Ferguson, S.S.2
Negishi, M.3
Goldstein, J.A.4
-
12
-
-
84865203418
-
Human CYP2C8 is post-transcriptionally regulated by microRNAs 103 and 107 in human liver
-
S.Y. Zhang, S. Surapureddi, S. Coulter, S.S. Ferguson, and J.A. Goldstein Human CYP2C8 is post-transcriptionally regulated by microRNAs 103 and 107 in human liver Mol Pharmacol 82 2012 529 540
-
(2012)
Mol Pharmacol
, vol.82
, pp. 529-540
-
-
Zhang, S.Y.1
Surapureddi, S.2
Coulter, S.3
Ferguson, S.S.4
Goldstein, J.A.5
-
13
-
-
79959501864
-
The ligands of estrogen receptor alpha regulate cytochrome P4502C9 (CYP2C9) expression
-
J. Mwinyi, I. Cavaco, B. Yurdakok, S. Mkrtchian, and M. Ingelman-Sundberg The ligands of estrogen receptor alpha regulate cytochrome P4502C9 (CYP2C9) expression J Pharmacol Exp Ther 338 2011 302 309
-
(2011)
J Pharmacol Exp Ther
, vol.338
, pp. 302-309
-
-
Mwinyi, J.1
Cavaco, I.2
Yurdakok, B.3
Mkrtchian, S.4
Ingelman-Sundberg, M.5
-
14
-
-
78751558863
-
Med25 is required for RNA polymerase II recruitment to specific promoters, thus regulating xenobiotic and lipid metabolism in human liver
-
R. Rana, S. Surapureddi, W. Kam, S. Ferguson, and J.A. Goldstein Med25 is required for RNA polymerase II recruitment to specific promoters, thus regulating xenobiotic and lipid metabolism in human liver Mol Cell Biol 31 2011 466 481
-
(2011)
Mol Cell Biol
, vol.31
, pp. 466-481
-
-
Rana, R.1
Surapureddi, S.2
Kam, W.3
Ferguson, S.4
Goldstein, J.A.5
-
15
-
-
79953166050
-
Isolation of primary human hepatocytes from normal and diseased liver tissue: A one hundred liver experience
-
R.H. Bhogal, J. Hodson, D.C. Bartlett, C.J. Weston, S.M. Curbishley, and E. Haughton et al. Isolation of primary human hepatocytes from normal and diseased liver tissue: a one hundred liver experience PLoS One 6 2011 e18222
-
(2011)
PLoS One
, vol.6
, pp. 18222
-
-
Bhogal, R.H.1
Hodson, J.2
Bartlett, D.C.3
Weston, C.J.4
Curbishley, S.M.5
Haughton, E.6
-
16
-
-
33646829646
-
Role of the Mediator complex in nuclear hormone receptor signaling
-
M. Belakavadi, and J.D. Fondell Role of the Mediator complex in nuclear hormone receptor signaling Rev Physiol Biochem Pharmacol 156 2006 23 43
-
(2006)
Rev Physiol Biochem Pharmacol
, vol.156
, pp. 23-43
-
-
Belakavadi, M.1
Fondell, J.D.2
-
17
-
-
77958111633
-
The metazoan Mediator co-activator complex as an integrative hub for transcriptional regulation
-
S. Malik, and R.G. Roeder The metazoan Mediator co-activator complex as an integrative hub for transcriptional regulation Nat Rev Genet 11 2010 761 772
-
(2010)
Nat Rev Genet
, vol.11
, pp. 761-772
-
-
Malik, S.1
Roeder, R.G.2
-
18
-
-
84880273878
-
Mechanisms of Mediator complex action in transcriptional activation
-
S.A. Ansari, and R.H. Morse Mechanisms of Mediator complex action in transcriptional activation Cell Mol Life Sci 70 2013 2743 2756
-
(2013)
Cell Mol Life Sci
, vol.70
, pp. 2743-2756
-
-
Ansari, S.A.1
Morse, R.H.2
-
19
-
-
23944510035
-
The nuclear receptors constitutive androstane receptor and pregnane X receptor cross-talk with hepatic nuclear factor 4α to synergistically activate the human CYP2C9 promoter
-
DOI 10.1124/jpet.105.087072
-
Y. Chen, G. Kissling, M. Negishi, and J.A. Goldstein The nuclear receptors constitutive androstane receptor and pregnane X receptor cross-talk with hepatic nuclear factor 4alpha to synergistically activate the human CYP2C9 promoter J Pharmacol Exp Ther 314 2005 1125 1133 (Pubitemid 41205977)
-
(2005)
Journal of Pharmacology and Experimental Therapeutics
, vol.314
, Issue.3
, pp. 1125-1133
-
-
Chen, Y.1
Kissling, G.2
Negishi, M.3
Goldstein, J.A.4
-
20
-
-
0034957480
-
Nuclear hormone receptors and gene expression
-
A. Aranda, and A. Pascual Nuclear hormone receptors and gene expression Physiol Rev 81 2001 1269 1304 (Pubitemid 32606670)
-
(2001)
Physiological Reviews
, vol.81
, Issue.3
, pp. 1269-1304
-
-
Aranda, A.1
Pascual, A.2
-
21
-
-
0012473279
-
The nuclear receptor superfamily: The second decade
-
D.J. Mangelsdorf, C. Thummel, M. Beato, P. Herrlich, G. Schutz, and K. Umesono et al. The nuclear receptor superfamily: the second decade Cell 83 1995 835 839
-
(1995)
Cell
, vol.83
, pp. 835-839
-
-
Mangelsdorf, D.J.1
Thummel, C.2
Beato, M.3
Herrlich, P.4
Schutz, G.5
Umesono, K.6
-
22
-
-
1342308232
-
Anatomy of the estrogen response element
-
DOI 10.1016/j.tem.2004.01.008
-
C.J. Gruber, D.M. Gruber, I.M. Gruber, F. Wieser, and J.C. Huber Anatomy of the estrogen response element Trends Endocrinol Metab 15 2004 73 78 (Pubitemid 38253009)
-
(2004)
Trends in Endocrinology and Metabolism
, vol.15
, Issue.2
, pp. 73-78
-
-
Gruber, C.J.1
Gruber, D.M.2
Gruber, I.M.L.3
Wieser, F.4
Huber, J.C.5
-
23
-
-
84865598963
-
MED25 is a Mediator component of HNF4alpha-driven transcription leading to insulin secretion in pancreatic beta-cells
-
E.H. Han, G.B. Rha, and Y.I. Chi MED25 is a Mediator component of HNF4alpha-driven transcription leading to insulin secretion in pancreatic beta-cells PLoS One 7 2012 e44007
-
(2012)
PLoS One
, vol.7
, pp. 44007
-
-
Han, E.H.1
Rha, G.B.2
Chi, Y.I.3
-
24
-
-
0025286261
-
A novel Mediator between activator proteins and the RNA polymerase II transcription apparatus
-
R.J. Kelleher 3rd, P.M. Flanagan, and R.D. Kornberg A novel Mediator between activator proteins and the RNA polymerase II transcription apparatus Cell 61 1990 1209 1215
-
(1990)
Cell
, vol.61
, pp. 1209-1215
-
-
Kelleher III, R.J.1
Flanagan, P.M.2
Kornberg, R.D.3
-
25
-
-
0033786937
-
Mediator of transcriptional regulation
-
L.C. Myers, and R.D. Kornberg Mediator of transcriptional regulation Annu Rev Biochem 69 2000 729 749
-
(2000)
Annu Rev Biochem
, vol.69
, pp. 729-749
-
-
Myers, L.C.1
Kornberg, R.D.2
-
26
-
-
18844451820
-
Mediator and the mechanism of transcriptional activation
-
DOI 10.1016/j.tibs.2005.03.011, PII S0968000405000836
-
R.D. Kornberg Mediator and the mechanism of transcriptional activation Trends Biochem Sci 30 2005 235 239 (Pubitemid 40693865)
-
(2005)
Trends in Biochemical Sciences
, vol.30
, Issue.5
, pp. 235-239
-
-
Kornberg, R.D.1
-
27
-
-
36248983165
-
Mediator complexes and eukaryotic transcription regulation: An overview
-
DOI 10.1016/j.biochi.2007.08.002, PII S0300908407002040
-
A. Casamassimi, and C. Napoli Mediator complexes and eukaryotic transcription regulation: an overview Biochimie 89 2007 1439 1446 (Pubitemid 350122855)
-
(2007)
Biochimie
, vol.89
, Issue.12
, pp. 1439-1446
-
-
Casamassimi, A.1
Napoli, C.2
-
28
-
-
84877575200
-
The Mediator complex in thyroid hormone receptor action
-
J.D. Fondell The Mediator complex in thyroid hormone receptor action Biochim Biophys Acta 1830 2013 3867 3875
-
(2013)
Biochim Biophys Acta
, vol.1830
, pp. 3867-3875
-
-
Fondell, J.D.1
-
29
-
-
34547812030
-
MED25 is distinct from TRAP220/MED1 in cooperating with CBP for retinoid receptor activation
-
H.K. Lee, U.H. Park, E.J. Kim, and S.J. Um MED25 is distinct from TRAP220/MED1 in cooperating with CBP for retinoid receptor activation EMBO J 26 2007 3545 3557
-
(2007)
EMBO J
, vol.26
, pp. 3545-3557
-
-
Lee, H.K.1
Park, U.H.2
Kim, E.J.3
Um, S.J.4
-
30
-
-
0037022631
-
The TRAP/mediator coactivator complex interacts directly with estrogen receptors α and β through the TRAP220 subunit and directly enhances estrogen receptor function in vitro
-
DOI 10.1073/pnas.261715899
-
Y.K. Kang, M. Guermah, C.X. Yuan, and R.G. Roeder The TRAP/Mediator coactivator complex interacts directly with estrogen receptors alpha and beta through the TRAP220 subunit and directly enhances estrogen receptor function in vitro Proc Natl Acad Sci U S A 99 2002 2642 2647 (Pubitemid 34240514)
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.5
, pp. 2642-2647
-
-
Kang, Y.K.1
Guermah, M.2
Yuan, C.-X.3
Roeder, R.G.4
|