Arginine enhances osteoblastogenesis and inhibits adipogenesis through the regulation of Wnt and NFATc signaling in human mesenchymal stem cells

International Journal of Molecular Sciences

Volumn 15, Issue 7, 2014, Pages 13010-13029

  Huh, Jeong Eun ^a   Choi, Jun Young ^a   Shin, Ye Ok ^a   Park, Dong Suk ^b   Kang, Jung Won ^a   Nam, Dongwoo ^a   Choi, Do Young ^a   Lee, Jae Dong ^a  

^a Kyung Hee University   (South Korea)

^b Kyung Hee University College of Medicine   (South Korea)

Author keywords

Adipogenesis; Arginine; Mesenchymal stem cells; NFATc Wnt signaling pathway; Osteoblastogenesis

Indexed keywords

ALKALINE PHOSPHATASE; ARGININE; BETA CATENIN; CCAAT ENHANCER BINDING PROTEIN ALPHA; COLLAGEN TYPE 1; COLLAGEN TYPE 2; DICKKOPF 1 PROTEIN; FATTY ACID BINDING PROTEIN 4; OSTEOCALCIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; SECRETED FRIZZLED RELATED PROTEIN 1; TRANSCRIPTION FACTOR NFAT; TRANSCRIPTION FACTOR OSTERIX; TRANSCRIPTION FACTOR RUNX2; WNT PROTEIN; MESSENGER RNA; NFATC1 PROTEIN, HUMAN;

ADIPOGENESIS; ARTICLE; BONE DEVELOPMENT; BONE MINERALIZATION; CELL DIFFERENTIATION; CELL PROLIFERATION ASSAY; CONTROLLED STUDY; HUMAN; HUMAN CELL; LYMPHOCYTE TRANSFORMATION; MESENCHYMAL STEM CELL; MRNA EXPRESSION ASSAY; OSTEOBLASTOGENESIS; PROTEIN SYNTHESIS REGULATION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING; WNT SIGNALING PATHWAY; CYTOLOGY; DRUG EFFECTS; GENETICS; MESENCHYMAL STROMA CELL; METABOLISM;

ADIPOGENESIS; ALKALINE PHOSPHATASE; ARGININE; CELL DIFFERENTIATION; COLLAGEN TYPE I; HUMANS; MESENCHYMAL STROMAL CELLS; NFATC TRANSCRIPTION FACTORS; OSTEOCALCIN; OSTEOGENESIS; RNA, MESSENGER; SIGNAL TRANSDUCTION; WNT PROTEINS;

EID: 84904653539     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms150713010     Document Type: Article

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