Enterovirus71 (EV71) utilise host microRNAs to mediate host immune system enhancing survival during infection

PLoS ONE

Volumn 9, Issue 7, 2014, Pages

  Lui, Yan Long Edmund ^a,b   Tan, Tuan Lin ^b   Woo, Wee Hong ^b   Timms, Peter ^a,c   Hafner, Louise Marie ^a   Tan, Kian Hwa ^b   Tan, Eng Lee ^b,d  

^a QUEENSLAND UNIVERSITY OF TECHNOLOGY   (Australia)

^b SINGAPORE POLYTECHNIC   (Singapore)

^c UNIVERSITY OF THE SUNSHINE COAST   (Australia)

^d NATIONAL UNIVERSITY HOSPITAL   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

CXCL11 CHEMOKINE; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INTERFERON; INTERFERON REGULATORY FACTOR 7; MICRORNA; MICRORNA 548; NUCLEOTIDE BINDING OLIGOMERIZATION DOMAIN LIKE RECEPTOR; PROTEIN VP1; RANTES; RETINOIC ACID INDUCIBLE PROTEIN I; STAT1 PROTEIN; TOLL LIKE RECEPTOR; UNCLASSIFIED DRUG; VIRUS PROTEIN; VIRUS RNA;

ARTICLE; CASP1 GENE; CCL5 GENE; CELL SURVIVAL; CONTROLLED STUDY; CXCL10 GENE; CXCL11 GENE; DDX58 GENE; DHX58 GENE; DOWN REGULATION; ENTEROVIRUS 71; ENTEROVIRUS INFECTION; GENE; GENE EXPRESSION; HOST PATHOGEN INTERACTION; HUMAN; HUMAN CELL; IFBB1 GENE; IRF7 GENE; ISG15 GENE; MX1 GENE; NONHUMAN; OAS2 GENE; RNA ANALYSIS; RNA SYNTHESIS; STAT1 GENE; UPREGULATION; VIRUS CELL INTERACTION; VIRUS IMMUNITY; VIRUS REPLICATION; VIRUS SURVIVAL; ENTEROVIRUS A; GENETICS; IMMUNE SYSTEM; TUMOR CELL LINE; VIROLOGY;

CELL LINE, TUMOR; ENTEROVIRUS A, HUMAN; ENTEROVIRUS INFECTIONS; HUMANS; IMMUNE SYSTEM; MICRORNAS; VIRUS REPLICATION;

EID: 84904600642     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0102997     Document Type: Article

References (66)

1. Lui YLE, Lin Z, Lee JJ, Chow VTK, Poh CL, et al. (2013) Beta-actin variant is necessary for Enterovirus 71 replication. Biochemical and Biophysical Research Communications 433: 607-610.
2. McMinn PC (2002) An overview of the evolution of enterovirus 71 and its clinical and public health significance. FEMS Microbiol Rev 26: 91-107.
3. McMinn PC (2012) Recent advances in the molecular epidemiology and control of human enterovirus 71 infection. Curr Opin Virol 2: 199-205.
4. Ooi MH, Wong SC, Lewthwaite P, Cardosa MJ, Solomon T (2010) Clinical features, diagnosis, and management of enterovirus 71. Lancet Neurol 9: 1097-1105.
5. Patel KP, Bergelson JM (2009) Receptors identified for hand, foot and mouth virus. Nat Med 15: 728-729.
6. Solomon T, Lewthwaite P, Perera D, Cardosa MJ, McMinn P, et al. (2010) Virology, epidemiology, pathogenesis, and control of enterovirus 71. Lancet Infect Dis 10: 778-790.
7. Wong SS, Yip CC, Lau SK, Yuen KY (2010) Human enterovirus 71 and hand, foot and mouth disease. Epidemiol Infect 138: 1071-1089.
8. Ho BC, Yu SL, Chen JJ, Chang SY, Yan BS, et al. (2011) Enterovirus-induced miR-141 contributes to shutoff of host protein translation by targeting the translation initiation factor eIF4E. Cell Host Microbe 9: 58-69.
9. Huang HI, Weng KF, Shih SR (2012) Viral and host factors that contribute to pathogenicity of enterovirus 71. Future Microbiol 7: 467-479.
10. Chu PY, Lin KH, Hwang KP, Chou LC, Wang CF, et al. (2001) Molecular epidemiology of enterovirus 71 in Taiwan. Arch Virol 146: 589-600. (Pubitemid 32258320)
11. Lee JJ, Seah JB, Chow VT, Poh CL, Tan EL (2011) Comparative proteome analyses of host protein expression in response to Enterovirus 71 and Coxsackievirus A16 infections. J Proteomics 74: 2018-2024.
12. Lee MS, Chang LY (2010) Development of enterovirus 71 vaccines. Expert Rev Vaccines 9: 149-156.
13. Lee MS, Tseng FC, Wang JR, Chi CY, Chong P, et al. (2012) Challenges to licensure of enterovirus 71 vaccines. PLoS Negl Trop Dis 6: e1737.
14. Viswanathan K, Fruh K, DeFilippis V (2010) Viral hijacking of the host ubiquitin system to evade interferon responses. Curr Opin Microbiol 13: 517-523.
15. tenOever BR (2013) RNA viruses and the host microRNA machinery. Nat Rev Microbiol 11: 169-180.
16. Taylor KE, Mossman KL (2013) Recent advances in understanding viral evasion of type I interferon. Immunology 138: 190-197.
17. Randall RE, Goodbourn S (2008) Interferons and viruses: an interplay between induction, signalling, antiviral responses and virus countermeasures. J Gen Virol 89: 1-47.
18. Rajsbaum R, Garcia-Sastre A (2013) Viral evasion mechanisms of early antiviral responses involving regulation of ubiquitin pathways. Trends Microbiol 21: 421-429.
19. Munday DC, Surtees R, Emmott E, Dove BK, Digard P, et al. (2012) Using SILAC and quantitative proteomics to investigate the interactions between viral and host proteomes. Proteomics 12: 666-672.
20. Versteeg GA, Garcia-Sastre A (2010) Viral tricks to grid-lock the type I interferon system. Curr Opin Microbiol 13: 508-516.
21. Thompson MR, Kaminski JJ, Kurt-Jones EA, Fitzgerald KA (2011) Pattern recognition receptors and the innate immune response to viral infection. Viruses 3: 920-940.
22. Oudshoorn D, Versteeg GA, Kikkert M (2012) Regulation of the innate immune system by ubiquitin and ubiquitin-like modifiers. Cytokine Growth Factor Rev 23: 273-282.
23. de Weerd NA, Nguyen T (2012) The interferons and their receptors-distribution and regulation. Immunol Cell Biol 90: 483-491.
24. Brennan K, Bowie AG (2010) Activation of host pattern recognition receptors by viruses. Curr Opin Microbiol 13: 503-507.
25. Boss IW, Renne R (2011) Viral miRNAs and immune evasion. Biochim Biophys Acta 1809: 708-714.
26. Kanarek N, Ben-Neriah Y (2012) Regulation of NF-kappaB by ubiquitination and degradation of the IkappaBs. Immunol Rev 246: 77-94.
27. Sullivan CS, Ganem D (2005) MicroRNAs and viral infection. Mol Cell 20: 3-7. (Pubitemid 41396557)
28. Scaria V, Hariharan M, Maiti S, Pillai B, Brahmachari SK (2006) Host-virus interaction: a new role for microRNAs. Retrovirology 3: 68.
29. Ghosh Z, Mallick B, Chakrabarti J (2009) Cellular versus viral microRNAs in host-virus interaction. Nucleic Acids Res 37: 1035-1048.
30. Lau NC, Lim LP, Weinstein EG, Bartel DP (2001) An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans. Science 294: 858-862. (Pubitemid 33032104)
31. Lee RC, Feinbaum RL, Ambros V (1993) The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 75: 843-854. (Pubitemid 24014542)
32. Skalsky RL, Cullen BR (2010) Viruses, microRNAs, and host interactions. Annu Rev Microbiol 64: 123-141.
33. Nathans R, Chu CY, Serquina AK, Lu CC, Cao H, et al. (2009) Cellular microRNA and P bodies modulate host-HIV-1 interactions. Mol Cell 34: 696-709.
34. Mack GS (2007) MicroRNA gets down to business. Nat Biotechnol 25: 631-638.
35. Lui Y, Timms P, Hafner L, Tan T, Tan K, et al. (2013) Characterisation of enterovirus 71 replication kinetics in human colorectal cell line, HT29. SpringerPlus 2: 267.
36. Berkhout B, Jeang KT (2007) RISCy business: MicroRNAs, pathogenesis, and viruses. J Biol Chem 282: 26641-26645. (Pubitemid 47501890)
37. Lecellier CH, Dunoyer P, Arar K, Lehmann-Che J, Eyquem S, et al. (2005) A cellular microRNA mediates antiviral defense in human cells. Science 308: 557-560. (Pubitemid 40570587)
38. Gottwein E, Cullen BR (2008) Viral and cellular microRNAs as determinants of viral pathogenesis and immunity. Cell Host Microbe 3: 375-387. (Pubitemid 351773098)
39. Sullivan CS (2008) New roles for large and small viral RNAs in evading host defences. Nat Rev Genet 9: 503-507.
40. Boss IW, Renne R (2010) Viral miRNAs: tools for immune evasion. Curr Opin Microbiol 13: 540-545.
41. Roberts AP, Jopling CL (2010) Targeting viral infection by microRNA inhibition. Genome Biol 11: 201.
42. Chable-Bessia C, Meziane O, Latreille D, Triboulet R, Zamborlini A, et al. (2009) Suppression of HIV-1 replication by microRNA effectors. Retrovirology 6: 26.
43. Triboulet R, Mari B, Lin Y, Chable-Bessia C, Bennasser Y, et al. (2007) Suppression of microRNA-silencing pathway by HIV-1 during virus replication. Science 315: 1579-1582. (Pubitemid 46449475)
44. Otsuka M, Jing Q, Georgel P, New L, Chen J, et al. (2007) Hypersusceptibility to vesicular stomatitis virus infection in Dicer1-deficient mice is due to impaired miR24 and miR93 expression. Immunity 27: 123-134. (Pubitemid 47089021)
45. Buck AH, Perot J, Chisholm MA, Kumar DS, Tuddenham L, et al. (2010) Posttranscriptional regulation of miR-27 in murine cytomegalovirus infection. RNA 16: 307-315.
46. Cameron JE, Yin Q, Fewell C, Lacey M, McBride J, et al. (2008) Epstein-Barr virus latent membrane protein 1 induces cellular MicroRNA miR-146a, a modulator of lymphocyte signaling pathways. J Virol 82: 1946-1958. (Pubitemid 351206940)
47. Huang J, Wang F, Argyris E, Chen K, Liang Z, et al. (2007) Cellular microRNAs contribute to HIV-1 latency in resting primary CD4+ T lymphocytes. Nat Med 13: 1241-1247. (Pubitemid 47530631)
48. Jopling CL, Schutz S, Sarnow P (2008) Position-dependent function for a tandem microRNA miR-122-binding site located in the hepatitis C virus RNA genome. Cell Host Microbe 4: 77-85. (Pubitemid 351944051)
49. Lanford RE, Hildebrandt-Eriksen ES, Petri A, Persson R, Lindow M, et al. (2010) Therapeutic silencing of microRNA-122 in primates with chronic hepatitis C virus infection. Science 327: 198-201.
50. Martinez I, Gardiner AS, Board KF, Monzon FA, Edwards RP, et al. (2008) Human papillomavirus type 16 reduces the expression of microRNA-218 in cervical carcinoma cells. Oncogene 27: 2575-2582. (Pubitemid 351550884)
51. Yoshikawa T, Takata A, Otsuka M, Kishikawa T, Kojima K, et al. (2012) Silencing of microRNA-122 enhances interferon-alpha signaling in the liver through regulating SOCS3 promoter methylation. Sci Rep 2: 637.
52. Wiertz E, Hill A, Tortorella D, Ploegh H (1997) Cytomegaloviruses use multiple mechanisms to elude the host immune response. Immunol Lett 57: 213-216. (Pubitemid 27319341)
53. Jopling CL, Norman KL, Sarnow P (2006) Positive and negative modulation of viral and cellular mRNAs by liver-specific microRNA miR-122. Cold Spring Harb Symp Quant Biol 71: 369-376.
54. Jopling CL, Yi M, Lancaster AM, Lemon SM, Sarnow P (2005) Modulation of hepatitis C virus RNA abundance by a liver-specific MicroRNA. Science 309: 1577-1581. (Pubitemid 41266486)
55. Randall G, Panis M, Cooper JD, Tellinghuisen TL, Sukhodolets KE, et al. (2007) Cellular cofactors affecting hepatitis C virus infection and replication. Proc Natl Acad Sci U S A 104: 12884-12889. (Pubitemid 47255249)
56. Wen BP, Dai HJ, Yang YH, Zhuang Y, Sheng R (2013) MicroRNA-23b Inhibits Enterovirus 71 Replication through Downregulation of EV71 VPl Protein. Intervirology 56: 195-200.
57. Zheng Z, Ke X, Wang M, He S, Li Q, et al. (2013) Human microRNA hsa-miR-296-5p suppresses Enterovirus 71 replication by targeting the viral genome. J Virol.
58. Ho BC, Yu IS, Lu LF, Rudensky A, Chen HY, et al. (2014) Inhibition of miR-146a prevents enterovirus-induced death by restoring the production of type I interferon. Nat Commun 5: 3344.
59. Li Y, Xie J, Xu X, Wang J, Ao F, et al. (2013) MicroRNA-548 down-regulates host antiviral response via direct targeting of IFN-lambda1. Protein Cell 4: 130-141.
60. Lo AK, To KF, Lo KW, Lung RW, Hui JW, et al. (2007) Modulation of LMP1 protein expression by EBV-encoded microRNAs. Proc Natl Acad Sci U S A 104: 16164-16169. (Pubitemid 350099379)
61. Xiao C, Rajewsky K (2009) MicroRNA control in the immune system: basic principles. Cell 136: 26-36.
62. Liu ML, Lee YP, Wang YF, Lei HY, Liu CC, et al. (2005) Type I interferons protect mice against enterovirus 71 infection. J Gen Virol 86: 3263-3269.
63. Lui YLE, Tan TL, Timms P, Hafner LM, Tan KH, et al. (2014) Elucidating the host-pathogen interaction between human colorectal cells and invading Enterovirus 71 using transcriptomics profiling. FEBS Open Bio 4: 426-431.
64. Reed LJ, Muench H (1938) A simple method of estimating fifty percent endpoints. The American Journal of Hygiene 27: 493-497.
65. Tan EL, Chow VT, Quak SH, Yeo WC, Poh CL (2008) Development of multiplex real-time hybridization probe reverse transcriptase polymerase chain reaction for specific detection and differentiation of Enterovirus 71 and Coxsackievirus A16. Diagn Microbiol Infect Dis 61: 294-301. (Pubitemid 351847799)
66. Livak KJ, Schmittgen TD (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25: 402-408. (Pubitemid 34164012)