The insulin-like growth factor axis: A biological mechanism linking physical activity to colorectal cancer survival

Cancer Epidemiology

Volumn 38, Issue 4, 2014, Pages 455-459

  Sax, Andrew T ^a   Jenkins, David G ^a   Devin, James L ^a   Hughes, Gareth I ^a   Bolam, Kate A ^a   Skinner, Tina L ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

Biomarker; Colorectal neoplasms; Exercise; Insulin like growth factor 1; Insulin like growth factor binding proteins

Indexed keywords

SOMATOMEDIN; SOMATOMEDIN BINDING PROTEIN 3; SOMATOMEDIN C;

ARTICLE; BIOAVAILABILITY; CANCER DIAGNOSIS; CANCER INCIDENCE; CANCER MORTALITY; CANCER RISK; CANCER SURVIVAL; CANCER SURVIVOR; CELL DIFFERENTIATION; CELL GROWTH; CELL PROLIFERATION; COLORECTAL CANCER; HUMAN; PHYSICAL ACTIVITY; PHYSICAL INACTIVITY; PRIORITY JOURNAL; COLORECTAL TUMOR; METABOLISM; MORTALITY; MOTOR ACTIVITY; PHYSIOLOGY;

COLORECTAL NEOPLASMS; HUMANS; MOTOR ACTIVITY; SOMATOMEDINS;

EID: 84904545323     PISSN: 18777821     EISSN: 1877783X     Source Type: Journal    
DOI: 10.1016/j.canep.2014.05.011     Document Type: Article

References (65)

1. Ferlay J., Shin H.R., Bray F., Forman D., Mathers C., Parkin D.M. GLOBOCAN 2008 v2.0, Cancer Incidence and Mortality Worldwide: IARC CancerBase No. 10 2010, International Agency for Research on Cancer, Lyon, France, Available from: http://globocan.iarc.fr [cited 02.05.13].
2. Danaei G., Vander Hoorn S., Lopez A.D., Murray C.J., Ezzati M. Causes of cancer in the world: comparative risk assessment of nine behavioural and environmental risk factors. Lancet 2005, 366(9499):1784-1793.
3. Ballard-Barbash R.R., Friedenreich C.M.C., Courneya K.S.K., Siddiqi S.M.S., McTiernan A.A., Alfano C.M.C. Physical activity, biomarkers, and disease outcomes in cancer survivors: a systematic review. J Natl Cancer Inst 2012 Jun 5, 104(11):815-840.
4. Denlinger C.S., Engstrom P.F. Colorectal cancer survivorship: movement matters. Cancer Prev Res 2011 Apr 3, 4(4):502-511.
5. Giovannucci E., Pollak M.N., Platz E.A., Willett W.C., Stampfer M.J., Majeed N., et al. A prospective study of plasma insulin-like growth factor-1 and binding protein-3 and risk of colorectal neoplasia in women. Cancer Epidemiol Biomarkers Prev 2000, 9(April (4)):345-349.
6. Giovannucci E. Insulin, insulin-like growth factors and colon cancer: a review of the evidence. J Nutr 2001, 131(November (11 Suppl.)):3109S-3120S.
7. Chi F., Wu R., Zeng Y.-C., Xing R., Liu Y. Circulation insulin-like growth factor peptides and colorectal cancer risk: an updated systematic review and meta-analysis. Mol Biol Rep 2012, 27(December):1-8.
8. Samad A.K.A., Taylor R.S., Marshall T., Chapman M.A.S. A meta-analysis of the association of physical activity with reduced risk of colorectal cancer. Colorectal Dis 2005, 7(May (3)):204-213.
9. Wolin K.Y., Yan Y., Colditz G.A., Lee I-M. Physical activity and colon cancer prevention: a meta-analysis. Br J Cancer 2009, 100(February (4)):611-616.
10. Boyle T., Keegel T., Bull F., Heyworth J., Fritschi L. Physical activity and risks of proximal and distal colon cancers: a systematic review and meta-analysis. JNCI J Natl Cancer Inst 2012, 104(October (20)):1548-1561.
11. Meyerhardt J.A.J., Giovannucci E.L.E., Ogino S.S., Kirkner G.J.G., Chan A.T.A., Willett W.W., et al. Physical activity and male colorectal cancer survival. Arch Intern Med 2009, 169(December (22)):2102-2108.
12. Meyerhardt J.A., Physical Activity Survival after colorectal cancer diagnosis. J Clin Oncol 2006, 24(May (22)):3527-3534.
13. Meyerhardt J.A. Impact of physical activity on cancer recurrence and survival in patients with stage III colon cancer: findings from CALGB 89803. J Clin Oncol 2006, 24(May (22)):3535-3541.
14. Haydon A.M.M., Macinnis R.J., English D.R., Giles G.G. Effect of physical activity and body size on survival after diagnosis with colorectal cancer. Gut 2006, 55(January (1)):62-67.
15. Boyle T. Physical activity and colon cancer: timing, intensity and sedentary behavior. Am J Lifestyle Med 2012, 6(May (3)):204-215.
16. Garber C.E., Blissmer B., Deschenes M.R., Franklin B.A., LaMonte M.J., Lee I.-M., et al. Quantity and quality of exercise for developing and maintaining cardiorespiratory, musculoskeletal, and neuromotor fitness in apparently healthy adults. Med Sci Sports Exerc 2011, 43(July (7)):1334-1359.
17. Lissner L. Recall of physical activity in the distant past: the 32-year follow-up of the prospective population study of women in Goteborg, Sweden. Am J Epidemiol 2004, 159(February (3)):304-307.
18. Courneya K.S., Booth C.M., Gill S., O'Brien P., Vardy J., Friedenreich C.M., et al. The Colon Health and Life-Long Exercise Change trial: a randomized trial of the National Cancer Institute of Canada Clinical Trials Group. Science 2008, 15(December (6)):271.
19. Wolin K.Y., Lee I-M., Colditz G.A., Glynn R.J., Fuchs C., Giovannucci E. Leisure-time physical activity patterns and risk of colon cancer in women. Science 2007, 121(12):2776-2781.
20. Harriss D.J., Cable N.T., George K., Reilly T., Renehan A.G., Haboubi N. Physical activity before and after diagnosis of colorectal cancer. Science 2007, 37(11):947-960.
21. Takahashi H.H., Kuriyama S.S., Tsubono Y.Y., Nakaya N.N., Fujita K.K., Nishino Y.Y., et al. Time spent walking and risk of colorectal cancer in Japan: the Miyagi Cohort study. Eur J Cancer Prev 2007, 16(September (5)):403-408.
22. Jones J.I., Clemmons D.R. Insulin-like growth factors and their binding proteins: biological actions. Endocr Rev 1995, 16(February (1)):3-34. Available from: http://ezproxy.library.uq.edu.au/login?url=http://www.ncbi.nlm.nih.gov/pubmed?otool=iauqulib.
23. Barozzi C.C., Ravaioli M.M., D'Errico A.A., Grazi G.L.G., Poggioli G.G., Cavrini G.G., et al. Relevance of biologic markers in colorectal carcinoma: a comparative study of a broad panel. Cancer 2002, 94(January (3)):647-657.
24. Renehan A.G., Zwahlen M., Minder C., O'Dwyer S.T., Shalet S.M., Egger M. Insulin-like growth factor (IGF)-I, IGF binding protein-3, and cancer risk: systematic review and meta-regression analysis. Lancet 2004, 363(April (9418)):1346-1353.
25. Kukliński A., Kamocki Z., Cepowicz D., Gryko M., Czyżewska J., Pawlak K., et al. Relationships between insulin-like growth factor i and selected clinico-morphological parameters in colorectal cancer patients. Pol Przegl Chir 2011, 83(May (5)):250-257.
26. Renehan A.G., Painter J.E., Atkin W.S., Potten C.S., Shalet S.M., O'dwyer S.T. High-risk colorectal adenomas and serum insulin-like growth factors. Science 2001, 88(January (1)):107-113.
27. Pollak M.N., Schernhammer E.S., Hankinson S.E. Insulin-like growth factors and neoplasia. Nat Rev Cancer 2004, 4(July (7)):505-518.
28. Gapstur S.M., Kopp P., Chiu B.C-H., Gann P.H., Colangelo L.A., Liu K. Longitudinal associations of age, anthropometric and lifestyle factors with serum total insulin-like growth factor-I and IGF binding protein-3 levels in Black and White men: the CARDIA Male Hormone Study. Cancer Epidemiol Biomarkers Prev 2004, 13(December (12)):2208-2216.
29. Harrela M., Koistinen H., Kaprio J., Lehtovirta M., Tuomilehto J., Eriksson J., et al. Genetic and environmental components of interindividual variation in circulating levels of IGF-I, IGF-II, IGFBP-1, and IGFBP-3. Science 1996, 98(December (11)):2612-2615.
30. Yu H., Mistry J., Nicar M.J., Khosravi M.J., Diamandis A., van Doorn J., et al. Insulin-like growth factors (IGF-I, free IGF-I and IGF-II) and insulin-like growth factor binding proteins (IGFBP-2, IGFBP-3, IGFBP-6, and ALS) in blood circulation. J Clin Lab Anal 1999, 13(4):166-172.
31. Clemmons D.R., Underwood L.E. Nutritional regulation of IGF-I and IGF binding proteins. Annu Rev Nutr 1991, 11(July (1)):393-412.
32. Yu H., Rohan T. Role of the insulin-like growth factor family in cancer development and progression. J Natl Cancer Inst 2000, 92(September (18)):1472-1489.
33. Stewart C.E., Rotwein P. Growth, differentiation, and survival: multiple physiological functions for insulin-like growth factors. Physiol Rev 1996, 76(October (4)):1005-1026.
34. Resnicoff M., Abraham D., Yutanawiboonchai W., Rotman H.L., Kajstura J., Rubin R., et al. The insulin-like growth factor i receptor protects tumor cells from apoptosis in vivo. Cancer Res 1995, 55(June (11)):2463-2469.
35. Frattali A.L., Pessin J.E. Relationship between alpha subunit ligand occupancy and beta subunit autophosphorylation in insulin/insulin-like growth factor-1 hybrid receptors. J Biol Chem 1993, 268(10):7393-7400.
36. O'Dell S.D., Day I.N.M. Molecules in focus insulin-like growth factor II (IGF-II). Int J Biochem Cell Biol 1998, 30(July (7)):767-771.
37. Guler H.P., Zapf J., Schmid C., Froesch E.R. Insulin-like growth factors I and II in healthy man. Estimations of half-lives and production rates. Acta Endocrinol 1989, 121(December (6)):753-758.
38. Gatti R.R., De Palo E.F.E., Antonelli G.G., Spinella P.P. IGF-I/IGFBP system: metabolism outline and physical exercise. J Endocrinol Invest 2012, 35(June (7)):699-707.
39. Clemmons D.R. Role of insulin-like growth factor binding proteins in controlling IGF actions. Mol Cell Endocrinol 1998, 140(May (1-2)):19-24.
40. Kelley K.M.K., Oh Y.Y., Gargosky S.E.S., Gucev Z.Z., Matsumoto T.T., Hwa V.V., et al. Insulin-like growth factor-binding proteins (IGFBPs) and their regulatory dynamics. Int J Biochem Cell Biol 1996, 28(May (6)):619-637.
41. Firth S.M., Baxter R.C. Cellular actions of the insulin-like growth factor binding proteins. Endocr Rev 2002, 23(December (6)):824-854.
42. Giovannucci E., Pollak M., Platz E.A., Willett W.C., Stampfer M.J., Majeed N., et al. Insulin-like growth factor I (IGF-I), IGF-binding protein-3 and the risk of colorectal adenoma and cancer in the Nurses' Health Study. Growth Horm IGF Res 2000, 10(April (Suppl. A)):S30-S31.
43. Ma J., Pollak M.N., Giovannucci E., Chan J.M., Tao Y., Hennekens C.H., et al. Prospective study of colorectal cancer risk in men and plasma levels of insulin-like growth factor (IGF)-I and IGF-binding protein-3. J Natl Cancer Inst 1999, 91(April (7)):620-625.
44. Kaaks R., Toniolo P., Akhmedkhanov A., Lukanova A., Biessy C., Dechaud H., et al. Serum C-peptide, insulin-like growth factor (IGF)-I, IGF-binding proteins, and colorectal cancer risk in women. J Natl Cancer Inst 2000, 92(19):1592-1600.
45. Probst-Hensch N.M., Yuan J.M., Stanczyk F.Z., Gao Y.T., Ross R.K., Yu M.C. IGF-1, IGF-2 and IGFBP-3 in prediagnostic serum: association with colorectal cancer in a cohort of Chinese men in Shanghai. Br J Cancer 2001, 85(11):1695.
46. Howlader N., Noone A.M., Krapcho M., Neyman N., Aminou R., Altekruse S.F., et al. SEER Cancer Statistics Review, 1975-2009 (Vintage 2009 Populations) 2012, National Cancer Institute, Bethesda, MD, Available from: http://seer.cancer.gov/statfacts/html/colorect.html#survival [cited 26.03.13].
47. Wu Y., Yakar S., Zhao L., Hennighausen L., LeRoith D. Circulating insulin-like growth factor-I levels regulate colon cancer growth and metastasis. Cancer Res 2002, 62(February (4)):1030-1035.
48. Glass A.R., Kikendall J.W., Sobin L.H., Bowen P.E. Serum concentrations of insulin-like growth factor 1 in colonic neoplasia. Acta Oncol 1994, 33(1):70-71.
49. Jacobs E.T., Martinez M.E., Alberts D.S., Ashbeck E.L., Gapstur S.M., Lance P., et al. Plasma insulin-like growth factor I is inversely associated with colorectal adenoma recurrence: a novel hypothesis. Cancer Epidemiol Biomarkers Prev 2008, 17(February (2)):300-305.
50. Hakam A., Yeatman T.J., Lu L., Mora L., Marcet G., Nicosia S.V., et al. Expression of insulin-like growth factor-1 receptor in human colorectal cancer. Hum Pathol 1999, 30(October (10)):1128-1133.
51. Tricoli J.V., Rall L.B., Karakousis C.P., Herrera L., Petrelli N.J., Bell G.I., et al. Enhanced levels of insulin-like growth factor messenger RNA in human colon carcinomas and liposarcomas. Cancer Res 1986, 46(December (12 Pt 1)):6169-6173.
52. Freier S., Weiss O., Eran M., Flyvbjerg A., Dahan R., Nephesh I. Expression of the insulin-like growth factors and their receptors in adenocarcinoma of the colon. BMJ 1999, 44(May (5)):704.
53. Wolpin B.M., Meyerhardt J.A., Chan A.T., Ng K., Chan J.A., Wu K., et al. Insulin, the insulin-like growth factor axis, and mortality in patients with nonmetastatic colorectal cancer. J Clin Oncol 2009, 27(January (2)):176-185.
54. Fuchs C.S., Goldberg R.M., Sargent D.J., Meyerhardt J.A., Wolpin B.M., Green E.M., et al. Plasma insulin-like growth factors, insulin-like binding protein-3, and outcome in metastatic colorectal cancer: results from intergroup trial N9741. Clin Cancer Res 2008, 14(December (24)):8263-8269.
55. Rarick K.R., Pikosky M.A., Grediagin A., Smith T.J., Glickman E.L., Alemany J.A., et al. Energy flux, more so than energy balance, protein intake, or fitness level, influences insulin-like growth factor-I system responses during 7 days of increased physical activity. J Appl Physiol 2007, 103(October (5)):1613-1621.
56. Rosendal L., Langberg H., Flyvbjerg A., Frystyk J., Ørskov H., Kjær M. Physical capacity influences the response of insulin-like growth factor and its binding proteins to training. J Appl Physiol 2002, 93(November (5)):1669-1675.
57. Nemet D., Connolly P.H., Pontello-Pescatello A.M., Rose-Gottron C., Larson J.K., Pietro Galassetti, et al. Negative energy balance plays a major role in the IGF-I response to exercise training. J Appl Physiol 2003, 96(December (1)):276-282.
58. Mina D.S., Connor M.K., Alibhai S.M., Toren P., Guglietti C., Matthew A.G., et al. Exercise effects on adipokines and the IGF axis in men with prostate cancer treated with androgen deprivation: a randomized study. Can Urol Assoc J 2013, 7(11-12):E692.
59. Irwin M.L., Varma K., Alvarez-Reeves M., Cadmus L., Wiley A., Chung G.G., et al. Randomized controlled trial of aerobic exercise on insulin and insulin-like growth factors in breast cancer survivors: the Yale Exercise and Survivorship study. Cancer Epidemiol Biomarkers Prev 2009, 18(January (1)):306-313.
60. Schmitz K.H. Safety and efficacy of weight training in recent breast cancer survivors to alter body composition, insulin, and insulin-like growth factor axis proteins. Cancer Epidemiol Biomarkers Prev 2005, 14(July (7)):1672-1680.
61. Fairey A.S., Courneya K.S., Field C.J., Bell G.J., Jones L.W., Mackey J.R. Effects of exercise training on fasting insulin, insulin resistance, insulin-like growth factors, and insulin-like growth factor binding proteins in postmenopausal breast cancer survivors: a randomized controlled trial. Cancer Epidemiol Biomarkers Prev 2003, 12(August (8)):721-727.
62. Lee D.H., Kim J.Y., Lee M.K., Lee C., Min J.-H., Jeong D.H., et al. Effects of a 12-week home-based exercise program on the level of physical activity, insulin, and cytokines in colorectal cancer survivors: a pilot study. Support Care Cancer 2013, 21(September (9)):2537-2545.
63. Haydon A.M.M. Physical activity, insulin-like growth factor 1, insulin-like growth factor binding protein 3, and survival from colorectal cancer. Gut 2006, 55(May (5)):689-694.
64. Schmitz K.H., Ahmed R.L., Yee D. Effects of a 9-month strength training intervention on insulin, insulin-like growth factor (IGF)-I, IGF-binding protein (IGFBP)-1, and IGFBP-3 in 30-50-year-old women. Cancer Epidemiol Biomarkers Prev 2002, 11(December (12)):1597-1604.
65. Smith A.T., Clemmons D.R., Underwood L.E., Ben-Ezra V., McMurray R. The effect of exercise on plasma somatomedin-C/insulinlike growth factor I concentrations. Metab Clin Exp 1987, 36(June (6)):533-537.