Multiple loading conditions analysis can improve the association between finite element bone strength estimates and proximal femur fractures: A preliminary study in elderly women

Bone

Volumn 67, Issue , 2014, Pages 71-80

  Falcinelli, Cristina ^a,b   Schileo, Enrico ^a   Balistreri, Luca ^a   Baruffaldi, Fabio ^a   Bordini, Barbara ^a   Viceconti, Marco ^c,f   Albisinni, Ugo ^a   Ceccarelli, Francesco ^d   Milandri, Luigi ^e   Toni, Aldo ^a   Taddei, Fulvia ^a  

^a RIZZOLI ORTHOPAEDIC INSTITUTE   (Italy)

^b UNIVERSITY OF ROME TOR VERGATA   (Italy)

^c UNIVERSITY OF SHEFFIELD   (United Kingdom)

^d UNIVERSITY OF PARMA   (Italy)

^e Ospedale di Faenza   (Italy)

^f CISTIB Centre for Computational Imaging and Simulation Technologies in Biomedicine INSIGNEO Institute for in silico Medicine Department of Mechanical Engineering The University of Sheffield   (United Kingdom)

Author keywords

Biomechanics; Bone strength; Case control study; Finite element analysis; Osteoporosis; Proximal femur fracture

Indexed keywords

AGED; BIOMECHANICS; BODY MASS; CASE CONTROL STUDY; FEMALE; FEMUR; FEMUR FRACTURE; FINITE ELEMENT ANALYSIS; FRAGILITY FRACTURE; HUMAN; METABOLISM; MIDDLE AGED; PATHOPHYSIOLOGY; PHYSIOLOGY; VERY ELDERLY;

AGED; AGED, 80 AND OVER; BIOMECHANICAL PHENOMENA; BODY MASS INDEX; CASE-CONTROL STUDIES; FEMALE; FEMORAL FRACTURES; FEMUR; FINITE ELEMENT ANALYSIS; HUMANS; MIDDLE AGED; OSTEOPOROTIC FRACTURES;

EID: 84904464013     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2014.06.038     Document Type: Article

References (49)

1. Cooper C., Cole Z., Holroyd S.C., Earl N.C., Harvey E.M., Dennison, et al. Secular trends in the incidence of hip and other osteoporotic fractures. Osteoporos Int 2011, 22:1277-1288.
2. Bouxsein M. Determinants of skeletal fragility. Best Pract Res Clin Rheumatol 2005, 19:897-911.
3. Seeman E., Delmas P. Bone quality - the material and structural basis of bone strength and fragility. N Engl J Med 2006, 354:2250-2261.
4. Cody D.D., Gross G.J., Hou F.J., Spencer H.J., Goldstein S.A., Fyhrie D.P. Femoral strength is better predicted by finite element models than QCT and DXA. J Biomech 1999, 32:1013-1020.
5. Bessho M., Ohnishi I., Matsuyama J., Matsumoto T., Imai K., Nakamura K. Prediction of strength and strain of the proximal femur by a CT-based finite element method. J Biomech 2007, 40:1745-1753.
6. Keyak J., Kaneko T., Tehranzadeh J., Skinner H. Predicting proximal femoral strength using structural engineering models. Clin Orthop Relat Res 2005, 347:219-228.
7. Nishiyama K.K., Gilchrist S., Guy P., Cripton P., Boyd S.K. Proximal femur bone strength estimated by a computationally fast finite element analysis in a sideways fall configuration. J Biomech 2013, 46:1231-1236.
8. Koivumäki J., Thevenot J., Pulkkinen P., Kuhn V., Link T.M., Eckstein F., et al. Cortical bone finite element models in the estimation of experimentally measured failure loads in the proximal femur. Bone 2012, 51:737-740.
9. Trabelsi N., Yosibash Z. Patient-specific finite-element analyses of the proximal femur with orthotropic material properties validated by experiments. J Biomech Eng 2011, 133:061001.
10. Schileo E., Taddei F., Cristofolini L., Viceconti M. Subject-specific finite element models implementing a maximum principal strain criterion are able to estimate failure risk and fracture location on human femurs tested in vitro. J Biomech 2008, 41:356-367.
11. Dall'Ara E., Luisier B., Schmidt R., Kainberger F., Zysset P., Pahr D. A nonlinear QCT-based finite element model validation study for the human femur tested in two configurations in vitro. Bone 2013, 52:27-38.
12. Keyak J.H., Sigurdsson S., Karlsdottir G.S., Oskarsdottir D., Sigmarsdottir A., Zhao S., et al. Male-female differences in the association between incident hip fracture and proximal femoral strength: a finite element analysis study. Bone 2011, 48:1239-1245.
13. Orwoll E.S., Marshall L.M., Nielson C.M., Cummings S.R., Lapidus J., Cauley J.A., et al. Finite element analysis of the proximal femur and hip fracture risk in older men. J Bone Miner Res 2009, 24:475-483.
14. Amin S., Kopperdhal D.L., Melton L.J., Achenbach S.J., Therneau T.M., Riggs B.L., et al. Association of hip strength estimates by finite-element analysis with fractures in women and men. J Bone Miner Res 2011, 26:1593-1600.
15. Kopperdahl D.L., Aspelund T., Hoffmann P.F., Sigurdsson S., Siggeirsdottir K., Harris T.B., et al. Assessment of incident spine and hip fractures in women and men using finite element analysis of CT scans. J Bone Miner Res 2013, 10.1002/jbmr.2069.
16. Keyak J.H., Sigurdsson S., Karlsdottir G.S., Oskarsdottir D., Sigmarsdottir A., Kornak J., et al. Effect of finite element model loading condition on fracture risk assessment in men and women: the AGES-Reykjavik study. Bone 2013, 57:18-29.
17. Lattanzi R., Baruffaldi F., Zannoni C., Viceconti M. Specialised CT scan protocols for 3-D pre-operative planning of total hip replacement. Med Eng Phys 2004, 26:237-245.
18. Kalender W.A., Felsenberg D., Genant H.K., Fischer M., Dequeker J., Reeve J. The European Spine Phantom-a tool for standardization and quality control in spinal bone mineral measurements by DXA and QCT. Eur J Radiol 1995, 20:83-92.
19. Schileo E., Taddei F., Malandrino A., Cristofolini L., Viceconti M. Subject-specific finite element models can accurately predict strain levels in long bones. J Biomech 2007, 40:2982-2989.
20. th World Congress of Biomechanics (WCB 2014) 2014, http://www.abstractsonline.com/Plan/ViewAbstract.aspx?sKey=acddcedd-8f3c-436c-a8cf-2346ca7c4d6e&cKey=c43dfcfc-ef3d-46ee-93ac-ab223341faf0&mKey=%7b0D04D93F-3CBF-4352-9F47-E1E75F25E684%7d.
21. Bergmann G., Deuretzbacher G., Heller M., Graichen F., Rohlmann A., Strauss J., et al. Hip contact forces and gait patterns from routine activities. J Biomech 2001, 34:859-871.
22. Grassi L., Schileo E., Taddei F., Zani L., Juszczyk M., Cristofolini L., et al. Accuracy of finite element predictions in sideways load configurations for the proximal human femur. J Biomech 2012, 45:394-399.
23. Helgason B., Taddei F., Pálsson H., Schileo E., Cristofolini L., Viceconti M., et al. A modified method for assigning material properties to FE models of bones. Med Eng Phys 2008, 30:444-453.
24. Taddei F., Schileo E., Helgason B., Cristofolini L., Viceconti M. The material mapping strategy influences the accuracy of CT-based finite element models of bones: an evaluation against experimental measurements. Med Eng Phys 2007, 29:973-979.
25. Schileo E., Dall'Ara E., Taddei F., Malandrino A., Schotkamp T., Baleani M., et al. An accurate estimation of bone density improves the accuracy of subject-specific finite element models. J Biomech 2008, 41:2483-2491.
26. Morgan E.F., Bayraktar H.H., Keaveny T.M. Trabecular bone modulus-density relationships depend on anatomic site. J Biomech 2003, 36:897-904.
27. Taddei F., Pancanti A., Viceconti M. An improved method for the automatic mapping of computed tomography numbers onto finite element models. Med Eng Phys 2004, 26:61-69.
28. Bayraktar H.H., Morgan E.F., Niebur G.L., Morris G.E., Wong E.K., Keaveny T.M. Comparison of the elastic and yield properties of human femoral trabecular and cortical bone tissue. J Biomech 2004, 37:27-35.
29. Vaeth M., Skovlund E. A simple approach to power and sample size calculations in logistic regression and Cox regression models. Stat Med 2004, 23:1781-1792.
30. Archer K.J., Lemeshow S., Hosmer D.W. Goodness-of-fit tests for logistic regression models when data are collected using a complex sampling design. Comput Stat Data Anal 2007, 51:4450-4464.
31. Danielson M.E., Beck T.J., Karlamangla A.S., Greendale G.A., Atkinson E.J., Lian Y., et al. A comparison of DXA and CT based methods for estimating the strength of the femoral neck in post-menopausal women. Osteoporos Int 2013, 24:1379-1388.
32. Ito M., Wakao N., Hida T., Matsui Y., Abe Y., Aoyagi K., et al. Analysis of hip geometry by clinical CT for the assessment of hip fracture risk in elderly Japanese women. Bone 2010, 46:453-457.
33. Wang Q., Teo J.W., Ghasem-Zadeh A., Seeman E. Women and men with hip fractures have a longer femoral neck moment arm and greater impact load in a sideways fall. Osteoporos Int 2009, 20:1151-1156.
34. Bell K.L., Loveridge N., Power J., Garrahan N., Meggitt B.F., Reeve J. Regional differences in cortical porosity in the fractured femoral neck. Bone 1999, 24:57-64.
35. Nazarian A., Muller J., Zurakowski D., Muller R., Snyder B. Densitometric, morphometric and mechanical distributions in the human proximal femur. J Biomech 2007, 40:2573-2579.
36. Pasco J.A., Seeman E., Henry M.J., Merriman E.N., Nicholson G.C., Kotowicz M.A. The population burden of fractures originates in women with osteopenia, not osteoporosis. Osteoporos Int 2006, 17:1404-1409.
37. Wainwright S., Marshall L., Ensrud K., Cauley J.A., Black D.M., Hillier T.A., et al. Hip fracture in women without osteoporosis. J Clin Endocrinol Metab 2005, 90:2787-2793.
38. Cummings S.R., Bates D., Black D.M. Clinical use of bone densitometry scientific review. JAMA 2013, 288:1889-1898.
39. Kanis J.A., Johnell O., Oden A., Dawson A., De Laet C., Jonsson B. Ten year probabilities of osteoporotic fractures according to BMD and diagnostic thresholds. Osteoporos Int 2001, 12:989-995.
40. Parkkari J., Kannus P., Palvanen M., Natri A., Vainio J., Aho H., et al. Clinical investigations majority of hip fractures occur as a result of a fall and impact on the greater trochanter of the femur: a prospective controlled hip fracture study with 206 consecutive patients. Calcif Tissue Int 1999, 65:183-187.
41. Bouxsein M.L., Szulc P., Munoz F., Thrall E., Sornay-Rendu E., Delmas P.D. Contribution of trochanteric soft tissues to fall force estimates, the factor of risk, and prediction of hip fracture risk. J Bone Miner Res 2007, 22:825-831.
42. Pinilla T.P., Boardman K.C., Bouxsein M.L., Myers E.R., Hayes W.C. Impact direction from a fall influences the failure load of the proximal femur as much as age-related bone loss. Calcif Tissue Int 1996, 58:231-235.
43. Van Den Kroonenberg A.J., Hayes W.C., McMahon T.A. Hip impact velocities and body configurations for voluntary falls from standing height. J Biomech 1996, 29:807-811.
44. Hamacher D., Singh N.B., Van Dieën J.H., Heller M.O., Taylor W.R. Kinematic measures for assessing gait stability in elderly individuals: a systematic review. J R Soc Interface 2011, 8:1682-1698.
45. Riggs B.L., Melton L.J., Robb R.A., Camp J.J., Atkinson E.J., Oberg A.L., et al. Population-based analysis of the relationship of whole bone strength indices and fall-related loads to age- and sex-specific patterns of hip and wrist fractures. J Bone Miner Res 2006, 21:315-323.
46. Eckstein F., Wunderer C., Boehm H., Kuhn V., Priemel M., Link T.M., et al. Reproducibility and side differences of mechanical tests for determining the structural strength of the proximal femur. J Bone Miner Res 2004, 19:379-385.
47. Juszczyk M., Cristofolini L., Viceconti M. The human proximal femur behaves linearly elastic up to failure under physiological loading conditions. J Biomech 2011, 44:2259-2266.
48. Poole K.E.S., Treece G.M., Mayhew P.M., Vaculik J., Dungl P., Horak M., et al. Cortical thickness mapping to identify focal osteoporosis in patients with hip fracture. PLoS One 2012, 7:e38466.
49. Nicolella D.P., Bredbenner T.L. Development of a parametric finite element model of the proximal femur using statistical shape and density modelling. Comput Methods Biomech Biomed Eng 2012, 15:101-110.