Population-based analysis of the relationship of whole bone strength indices and fall-related loads to age- and sex-specific patterns of hip and wrist fractures

Journal of Bone and Mineral Research

Volumn 21, Issue 2, 2006, Pages 315-323

  Riggs, B Lawrence ^a,c   Melton III, L Joseph ^a   Robb, Richard A ^a   Camp, Jon J ^a   Atkinson, Elizabeth J ^a   Oberg, Ann L ^a   Rouleau, Peggy A ^a   McCollough, Cynthia H ^a   Khosla, Sundeep ^a   Bouxsein, Mary L ^b  

^a Mayo Clinic   (United States)

^b BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^c MAYO CLINIC   (United States)

Author keywords

Bone quality; Falls; Osteoporosis

Indexed keywords

ADULT; AGED; ARTICLE; BIOMECHANICS; BONE DENSITY; BONE STRENGTH; CONTROLLED STUDY; FALLING; FEMALE; HIP FRACTURE; HUMAN; INCIDENCE; MAJOR CLINICAL STUDY; MALE; POPULATION RESEARCH; RISK ASSESSMENT; SEX RATIO; WEIGHT BEARING; WRIST FRACTURE;

ACCIDENTAL FALLS; ADULT; AGE FACTORS; AGED; AGED, 80 AND OVER; BONE DENSITY; DENSITOMETRY, X-RAY; FEMALE; FEMORAL NECK FRACTURES; HIP; HIP FRACTURES; HUMANS; MALE; MIDDLE AGED; RADIUS; RADIUS FRACTURES; SEX FACTORS; WEIGHT-BEARING;

EID: 33144479729     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1359/JBMR.051022     Document Type: Article

References (50)

1. Marshall D, Johnell O, Wedel H 1996 Meta-analysis of how well measures of bone mineral density predict occurrence of osteoporotic fractures. BMJ 312:1254-1259.
2. Cummings SR, Bates D, Black DM 2002 Clinical use of bone densitometry. JAMA 288:1889-1897.
3. Carter DR, Bouxsein ML, Marcus R 1992 New approaches for interpreting projected bone densitometry data. J Bone Miner Res 7:137-145.
4. Seeman E 1997 From density to structure: Growing up and growing old on the surfaces of bone. J Bone Miner Res 12:509-521.
5. Nelson HD, Helfand M, Woolf SH, Allan JD 2002 Screening for postmenopausal osteoporosis: A review of the evidence for the U.S. Preventive Services Task Force. Ann Intern Med 137:529-541.
6. Riggs BL, Wahner HW, Seeman E, Offord KP, Dunn WL, Mazess RB, Johnson KA, Melton LJ III 1982 Changes in bone mineral density of the proximal femur and spine with aging: Differences between the postmenopausal and senile osteoporosis syndromes. J Clin Invest 70:716-723.
7. Riggs BL, Melton LJI, Robb RA, Camp JJ, Atkinson EJ, Peterson JM, Rouleau PA, McCollough CH, Bouxsein ML, Khosla S 2004 Population-based study of age and sex differences in bone volumetric density, size, geometry, and structure at different skeletal sites. J Bone Miner Res 19:1945-1954.
8. Hayes WC, Piazza SJ, Zysset PK 1991 Biomechanics of fracture risk prediction of the hip and spine by quantitative computed tomography. Radiol Clin North Am 29:1-18.
9. Hayes WC, Myers ER, Morris JN, Gerhart TN, Yett HS, Lipsitz LA 1993 Impact near the hip dominates fracture risk in elderly nursing home residents who fall. Calcif Tissue Int 52:192-198.
10. Nevitt MC, Cummings SR for the Fractures SoO Group 1993 Type of fall and risk of hip and wrist fractures: The study of osteoporotic fractures. J Am Geriatr Soc 41:1226-1234.
11. Palvanen M, Kannus P, Parkkari J, Pitkajarvi T, Pasanen M, Vuori I, Jarvinen M 2000 The injury mechanisms of osteoporotic upper extremity fractures among older adults: A controlled study of 287 consecutive patients and their 108 controls. Osteoporos Int 11:822-831.
12. Robinovitch S, Hayes W, McMahon TA 1997 Predicting the impact response of a nonlinear, single-degree-of-freedom shock-absorbing system from the measured step response. J Biomech Eng 119:221-227.
13. Bouxsein ML 1999 Application of biomechanics to the aging human skeleton. In: Glowacki J, Rosen CJ, Bilezikian JP (eds.) The Aging Skeleton. Academic Press, San Diego, CA, USA, pp. 315-330.
14. Lochmuller E-M, Lill CA, Kuhn V, Schneider E, Eckstein F 2002 Radius bone strength in bending, compression, and falling and its correlation with clinical densitometry at multiple sites. J Bone Miner Res 17:1629-1638.
15. Pistoia W, Van Rietbergen B, Lochmuller E-M, Lill CA, Eckstein F, Ruegsegger P 2002 Estimation of distal radius failure load with micro-finite element analysis models based on three-dimensional peripheral quantitative computed tomography images. Bone 30:842-848.
16. Crawford RP, Cann CE, Keaveny TM 2003 Finite element models predict in vitro vertebral body compressive strength better than quantitative computed tomography. Bone 33:744-750.
17. Duan Y, Beck TJ, Wang X-F, Seeman E 2003 Structural and biomechanical basis of sexual dimorphism in femoral neck fragility has its origins in growth and aging. J Bone Miner Res 18:1766-1774.
18. Looker AC, Beck TJ, Orwoll ES 2001 Does body size account for gender differences in femur bone density and geometry? J Bone Miner Res 16:1291-1299.
19. Melton LJ III, Beck TJ, Amin S, Khosla S, Achenbach SJ, Oberg AL, Riggs BL 2005 Contributions of bone density and structure to fracture risk assessment in men and women. Osteoporos Int 16:460-467.
20. Cummings SR, Melton LJ 2002 Epidemiology and outcomes of osteoporotic fractures. Lancet 359:1761-1767.
21. Eastell R, Riggs BL, Wahner HW, O'Fallon WM, Amadio PC, Melton LJ III 1989 Colles' fracture and bone density of the ultradistal radius. J Bone Miner Res 4:607-613.
22. Camp JJ, Karwoski RA, Stacy MC, Atkinson EJ, Khosla S, Melton LJ, Riggs BL, Robb RA 2004 A system for the analysis of whole-bone strength from helical CT images. Proc SPIE 5369:74-88.
23. Cann CE 1988 Quantitative CT for determination of bone mineral density: A review. Radiology 166:509-522.
24. Hibbeler RC 2004 Mechanics of Materials, 5th ed. Brooks/Cole, Pacific Grove, CA, USA.
25. Keaveny TM, Morgan EF, Niebur GL, Yeh OC 2001 Biomechanics of trabecular bone. Annu Rev Biomed Eng 3:307-333.
26. Whealan KM, Kwak D, Tedrow JR, Inoue K, Snyder BD 2000 Noninvasive imaging predicts failure load of the spine with simulated osteolytic defects. J Bone Joint Surg Am 82:1240-1251.
27. Hong J, Cabe GD, Tedrow JR, Hipp JA, Snyder BD 2004 Failure of trabecular bone with simulated lytic defects can be predicted non-invasively by structural analysis. J Orthop Res 22:479-486.
28. Kopperdahl DL, Pearlman JL, Keaveny TM 2000 Biomechanical consequences of an isolated overload on the human vertebral body. J Orthop Res 18:685-690.
29. van den Kroonenberg A, Hayes W, McMahon TA 1996 Hip impact velocities and body configurations for experimental falls from standing height. J Biomech 29:807-811.
30. Robinovitch S, Hayes WC, McMahon TA 1991 Prediction of femoral impact forces in falls on the hip. J Biomech Eng 113:366-374.
31. Chiu J, Robinovitch SN 1998 Prediction of upper extremity impact forces during falls on the outstretched hand. J Biomech 31:1169-1176.
32. Melton LJ III 1996 History of the Rochester Epidemiology Project. Mayo Clin Proc 71:266-274.
33. Melton LJI, Therneau TM, Larson DR 1998 Long-term trends in hip fracture prevalence: The influence of hip fracture incidence and survival. Osteoporos Int 8:68-74.
34. Melton LJ III, Amadio PC, Crowson CS, O'Fallon WM 1998 Long-term trends in the incidence of distal forearm fractures. Osteoporos Int 8:341-348.
35. Venables WN, Ripley BD 1994 Modern Applied Statistics with S-Plus. Springer-Verlag, New York, NY, USA.
36. Seeman E 1997 From density to structure: Growing up and growing old on the surgaces of bone. J Bone Miner Res 12:509-520.
37. Winner SJ, Morgan CA, Evans JG 1989 Perimenopausal risk of falling and incidence of distal forearm fracture. BMJ 298:1486-1488.
38. Riggs BL, Parfitt AM 2005 Drugs used to treat osteoporosis: The critical need for a uniform nomenclature based on their action on bone remodeling. J Bone Miner Res 20:177-184.
39. Silva MJ, Gibson LJ 1997 Modeling the mechanical behavior of vertebral trabecular bone: Effects of age-related changes in microstructure. Bone 21:191-199.
40. Garnero P, Sornay-Rendu E, Chapuy M, Delmas PD 1996 Increased bone turnover in late postmenopausal women is a major determinant of osteoporosis. J Bone Miner Res 11:337-349.
41. Khosla SK, Atkinson EJ, Melton LJ III, Riggs BL 1997 Effects of age and estrogen status on serum parathyroid hormone levels and biochemical markers of bone turnover in women: A population-based study. J Clin Endocrinol Metab 82:1522-1527.
42. Neff M, Dambacher MA, Qin L, Kissling R, Ruegsegger P 2002 2- and 3-dimensional bone structures in vivo and in vitro. Osteologie 11:67-77.
43. Wehrli FW, Gomberg BR, Saha PK, Song HK, Hwang SN, Snyder PJ 2001 Digital topological analysis of in vivo magnetic resonance microimages of trabecular bone reveals structural implications of osteoporosis. J Bone Miner Res 16:1520-1531.
44. Wehrli FW, Hilaire L, Fernandez-Seara M, Gomberg BR, Song HK, Zemel BS, Loh L, Snyder PJ 2002 Quantitative magnetic resonance imaging in the calcaneus and femur of women with varying degrees of osteopenia and vertebral deformity status. J Bone Miner Res 17:2265-2273.
45. Link TM, Vieth V, Matheis J, Newitt D, Lu Y, Rummeny EJ, Majumdar S 2002 Bone structure of the distal radius and the calcaneus vs BMD of the spine and proximal, femur in the prediction of osteoporotic spine fractures. Eur Radiol 12:401-408.
46. Gryfe CI, Amies A, Ashley MJ 1977 A longitudinal study of falls in an elderly population. I. Incidence and morbidity. Age Ageing 6:201-210.
47. Baker SP, Harvey AH 1985 Fall injuries in the elderly. Symposium on falls in the elderly: Biologic and behavioral aspects. Clin Geriatr Med 1:501-512.
48. Chapuy MC, Arlot ME, Duboeuf F, Brun J, Crouzet B, Arnaud S, Delmas PD, Meunier PJ 1992 Vitamin D3 and calcium to prevent hip fractures in elderly women. N Engl J Med 327:1637-1642.
49. Aaron JE, Gallagher JC, Nordin BEC 1974 Seasonal variation of histological osteomalacia in femoral neck fractures. Lancet ii:84-85.
50. Schwartz AW, Capezuti E, Grisso JA 2001 Falls as risk factors for fractures. In: Marcus R, Feldman D, Kelsey J (eds.) Osteoporosis, 2nd ed. Academic Press, San Diego, CA, USA, pp. 795-807.