Inactivation of Rb and E2f8 synergizes to trigger stressed DNA replication during erythroid terminal differentiation

Molecular and Cellular Biology

Volumn 34, Issue 15, 2014, Pages 2833-2847

  Ghazaryan, Seda ^a   Sy, Chandler ^a   Hu, Tinghui ^a   An, Xiuli ^b   Mohandas, Narla ^b   Fu, Haiqing ^c   Aladjem, Mirit I ^c   Chang, Victor T ^d   Opavsky, Rene ^e   Wu, Lizhao ^a  

^a New Jersey Medical School University Hospital Cancer Center   (United States)

^b NEW YORK BLOOD CENTER   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

^d VETERANS AFFAIRS MEDICAL CENTER   (United States)

^e UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RETINOBLASTOMA PROTEIN; TRANSCRIPTION FACTOR E2F; TRANSCRIPTION FACTOR E2F8; UNCLASSIFIED DRUG;

ANEMIA; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BINDING SITE; BLOOD CELL COUNT; CELL CYCLE PROGRESSION; CELL DIFFERENTIATION; CHROMATIN IMMUNOPRECIPITATION; COMPARATIVE STUDY; CONTROLLED STUDY; DNA DAMAGE; DNA REPLICATION; ERYTHROID CELL; ERYTHROID TERMINAL DIFFERENTIATION; ERYTHROPOIESIS; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE INACTIVATION; IMMUNOPRECIPITATION; IN VITRO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSCRIPTION INITIATION; UPREGULATION;

ANIMALS; BINDING SITES; CELL CYCLE; CELL CYCLE PROTEINS; CELL DIFFERENTIATION; DNA REPLICATION; DNA-BINDING PROTEINS; ERYTHROID CELLS; ERYTHROPOIESIS; GENE EXPRESSION PROFILING; MICE; MICE, KNOCKOUT; PROMOTER REGIONS, GENETIC; REPRESSOR PROTEINS; RETINOBLASTOMA; TRANSCRIPTIONAL ACTIVATION;

EID: 84904356098     PISSN: 02707306     EISSN: 10985549     Source Type: Journal    
DOI: 10.1128/MCB.01651-13     Document Type: Article

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