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Volumn 387, Issue 8, 2014, Pages 707-718

cGMP: Transition from bench to bedside: A report of the 6th International Conference on cGMP Generators, Effectors and Therapeutic Implications

Author keywords

Cardiovascular diseases; cGMP; Nitric oxide; Particulate guanylyl cyclase; sGC stimulator; Soluble guanylyl cyclase

Indexed keywords

ATRIAL NATRIURETIC FACTOR; BACTERIAL PROTEIN; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CYCLIC GMP; GUANYLATE CYCLASE; HEAT SHOCK PROTEIN 90; HEME; MICRORNA; MICRORNA 425; NITRIC OXIDE; PARTICULATE GUANYLYL CYCLASE; PROTEIN DISULFIDE ISOMERASE; PROTEIN EXOY; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SOLUBLE GUANYLYL CYCLASE; THYROID HORMONE; UNCLASSIFIED DRUG; CELL RECEPTOR; NATRIURETIC FACTOR;

EID: 84904326480     PISSN: 00281298     EISSN: 14321912     Source Type: Journal    
DOI: 10.1007/s00210-014-0999-8     Document Type: Review
Times cited : (12)

References (55)
  • 1
    • 84874740630 scopus 로고    scopus 로고
    • Crystal structures of the catalytic domain of human soluble guanylate cyclase
    • Allerston CK, von Delft F, Gileadi O (2013) Crystal structures of the catalytic domain of human soluble guanylate cyclase. PLoS One 8:e57644
    • (2013) PLoS One , vol.8
    • Allerston, C.K.1    Von Delft, F.2    Gileadi, O.3
  • 2
    • 84875231565 scopus 로고    scopus 로고
    • Sildenafil and diastolic dysfunction after acute myocardial infarction in patients with preserved ejection fraction: The Sildenafil and Diastolic Dysfunction After Acute Myocardial Infarction (SIDAMI) trial
    • Andersen MJ et al (2013) Sildenafil and diastolic dysfunction after acute myocardial infarction in patients with preserved ejection fraction: the Sildenafil and Diastolic Dysfunction After Acute Myocardial Infarction (SIDAMI) trial. Circulation 127:1200-1208
    • (2013) Circulation , vol.127 , pp. 1200-1208
    • Andersen, M.J.1
  • 3
    • 84881238374 scopus 로고    scopus 로고
    • Atrial natriuretic peptide is negatively regulated by microRNA-425
    • Arora P et al (2013) Atrial natriuretic peptide is negatively regulated by microRNA-425. J Clin Invest 123:3378-3382
    • (2013) J Clin Invest , vol.123 , pp. 3378-3382
    • Arora, P.1
  • 4
    • 84863229962 scopus 로고    scopus 로고
    • Cardiac natriuretic peptides act via p38MAPK to induce the brown fat thermogenic program in mouse and human adipocytes
    • Bordicchia M et al (2012) Cardiac natriuretic peptides act via p38MAPK to induce the brown fat thermogenic program in mouse and human adipocytes. J Clin Invest 2012
    • (2012) J Clin Invest , vol.2012
    • Bordicchia, M.1
  • 5
    • 79960914260 scopus 로고    scopus 로고
    • A genetic variant of the atrial natriuretic peptide gene is associated with cardiometabolic protection in the general community
    • Cannone V et al (2011) A genetic variant of the atrial natriuretic peptide gene is associated with cardiometabolic protection in the general community. J Am Coll Cardiol 58:629-636
    • (2011) J Am Coll Cardiol , vol.58 , pp. 629-636
    • Cannone, V.1
  • 6
    • 84886379425 scopus 로고    scopus 로고
    • The atrial natriuretic peptide genetic variant rs5068 is associated with a favorable cardiometabolic phenotype in a Mediterranean population
    • Cannone V et al (2013) The atrial natriuretic peptide genetic variant rs5068 is associated with a favorable cardiometabolic phenotype in a Mediterranean population. Diabetes 36:2850-2856
    • (2013) Diabetes , vol.36 , pp. 2850-2856
    • Cannone, V.1
  • 9
    • 84555177777 scopus 로고    scopus 로고
    • Atrial natriuretic peptide enhances microvascular albumin permeability by the caveolae-mediated transcellular pathway
    • Chen W et al (2012b) Atrial natriuretic peptide enhances microvascular albumin permeability by the caveolae-mediated transcellular pathway. Cardiovasc Res 93:141-151
    • (2012) Cardiovasc Res , vol.93 , pp. 141-151
    • Chen, W.1
  • 10
    • 84883291942 scopus 로고    scopus 로고
    • Atrial natriuretic peptide-mediated inhibition of microcirculatory endothelial Ca2+ and permeability response to histamine involves cGMP-dependent protein kinase I and TRPC6 channels
    • Chen W et al (2013) Atrial natriuretic peptide-mediated inhibition of microcirculatory endothelial Ca2+ and permeability response to histamine involves cGMP-dependent protein kinase I and TRPC6 channels. Arterioscler Thromb Vasc Biol 33:2121-2129
    • (2013) Arterioscler Thromb Vasc Biol , vol.33 , pp. 2121-2129
    • Chen, W.1
  • 11
    • 84861888611 scopus 로고    scopus 로고
    • Hydrogen sulfide and nitric oxide are mutually dependent in the regulation of angiogenesis and endothelium-dependent vasorelaxation
    • Coletta C et al (2012) Hydrogen sulfide and nitric oxide are mutually dependent in the regulation of angiogenesis and endothelium-dependent vasorelaxation. Proc Natl Acad Sci U S A 109:9161-9166
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 9161-9166
    • Coletta, C.1
  • 12
    • 84861857184 scopus 로고    scopus 로고
    • Structure and regulation of soluble guanylate cyclase
    • Derbyshire ER, Marletta MA (2012) Structure and regulation of soluble guanylate cyclase. Annu Rev Biochem 81:533-559
    • (2012) Annu Rev Biochem , vol.81 , pp. 533-559
    • Derbyshire, E.R.1    Marletta, M.A.2
  • 13
    • 80053907554 scopus 로고    scopus 로고
    • Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk
    • Ehret GB et al (2011) Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature 478:103-109
    • (2011) Nature , vol.478 , pp. 103-109
    • Ehret, G.B.1
  • 14
    • 84890557979 scopus 로고    scopus 로고
    • Dysfunctional nitric oxide signalling increases risk of myocardial infarction
    • Erdmann J et al (2013) Dysfunctional nitric oxide signalling increases risk of myocardial infarction. Nature 504:432-436
    • (2013) Nature , vol.504 , pp. 432-436
    • Erdmann, J.1
  • 15
    • 77950190436 scopus 로고    scopus 로고
    • Distribution and development of brown adipocytes in the murine and human adipose organ
    • Frontini A, Cinti S (2010) Distribution and development of brown adipocytes in the murine and human adipose organ. Cell 11:253-256
    • (2010) Cell , vol.11 , pp. 253-256
    • Frontini, A.1    Cinti, S.2
  • 16
    • 84880732460 scopus 로고    scopus 로고
    • Riociguat for the treatment of chronic thromboembolic pulmonary hypertension
    • Ghofrani HA et al (2013a) Riociguat for the treatment of chronic thromboembolic pulmonary hypertension. N Engl J Med 369:319-329
    • (2013) N Engl J Med , vol.369 , pp. 319-329
    • Ghofrani, H.A.1
  • 17
    • 84880721470 scopus 로고    scopus 로고
    • Riociguat for the treatment of pulmonary arterial hypertension
    • Ghofrani HA et al (2013b) Riociguat for the treatment of pulmonary arterial hypertension. N Engl J Med 369:330-340
    • (2013) N Engl J Med , vol.369 , pp. 330-340
    • Ghofrani, H.A.1
  • 18
    • 84864720613 scopus 로고    scopus 로고
    • Soluble guanylyl cyclase requires heat shock protein 90 for heme insertion during maturation of the NO-active enzyme
    • Ghosh A, Stuehr DJ (2012) Soluble guanylyl cyclase requires heat shock protein 90 for heme insertion during maturation of the NO-active enzyme. Proc Natl Acad Sci U S A 109:12998-13003
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 12998-13003
    • Ghosh, A.1    Stuehr, D.J.2
  • 19
    • 84898807530 scopus 로고    scopus 로고
    • Transgenic mice for real-time visualization of cGMP in intact adult cardiomyocytes
    • Gotz KR et al (2014) Transgenic mice for real-time visualization of cGMP in intact adult cardiomyocytes. Circ Res 114:1235-1245
    • (2014) Circ Res , vol.114 , pp. 1235-1245
    • Gotz, K.R.1
  • 20
    • 77950361100 scopus 로고    scopus 로고
    • Protein kinase g controls brown fat cell differentiation and mitochondrial biogenesis
    • Haas B et al (2009) Protein kinase g controls brown fat cell differentiation and mitochondrial biogenesis. Sci Signal 2:ra78
    • (2009) Sci Signal , vol.2
    • Haas, B.1
  • 22
    • 84876915639 scopus 로고    scopus 로고
    • Protein disulfide-isomerase interacts with soluble guanylyl cyclase via a redox-based mechanism and modulates its activity
    • Heckler EJ, Crassous PA, Baskaran P, Beuve A (2013) Protein disulfide-isomerase interacts with soluble guanylyl cyclase via a redox-based mechanism and modulates its activity. Biochem J 452:161-169
    • (2013) Biochem J , vol.452 , pp. 161-169
    • Heckler, E.J.1    Crassous, P.A.2    Baskaran, P.3    Beuve, A.4
  • 23
    • 84856733306 scopus 로고    scopus 로고
    • cGMP-Prkg1 signaling and Pde5 inhibition shelter cochlear hair cells and hearing function
    • Jaumann M et al (2012) cGMP-Prkg1 signaling and Pde5 inhibition shelter cochlear hair cells and hearing function. Nat Med 18:252-259
    • (2012) Nat Med , vol.18 , pp. 252-259
    • Jaumann, M.1
  • 24
    • 84894132767 scopus 로고    scopus 로고
    • A new era in brown adipose tissue biology: Molecular control of brown fat development and energy homeostasis
    • Kajimura S, Saito M (2013) A new era in brown adipose tissue biology: molecular control of brown fat development and energy homeostasis. Annu Rev Physiol 76:225-249
    • (2013) Annu Rev Physiol , vol.76 , pp. 225-249
    • Kajimura, S.1    Saito, M.2
  • 25
    • 84875879087 scopus 로고    scopus 로고
    • Interstitial cells of Cajal integrate excitatory and inhibitory neurotransmission with intestinal slow-wave activity
    • Klein S et al (2013) Interstitial cells of Cajal integrate excitatory and inhibitory neurotransmission with intestinal slow-wave activity. Nat Commun 4:1630
    • (2013) Nat Commun , vol.4 , pp. 1630
    • Klein, S.1
  • 26
    • 84873330378 scopus 로고    scopus 로고
    • 67-kDa laminin receptor increases cGMP to induce cancer-selective apoptosis
    • Kumazoe M et al (2012) 67-kDa laminin receptor increases cGMP to induce cancer-selective apoptosis. J Clin Invest 123:787-799
    • (2012) J Clin Invest , vol.123 , pp. 787-799
    • Kumazoe, M.1
  • 27
    • 67149084605 scopus 로고    scopus 로고
    • Pharmacodynamics of a novel designer natriuretic peptide, CD-NP, in a first-in-human clinical trial in healthy subjects
    • Lee CY, Chen HH, Lisy O, Swan S, Cannon C, Lieu HD, Burnett JC Jr (2009) Pharmacodynamics of a novel designer natriuretic peptide, CD-NP, in a first-in-human clinical trial in healthy subjects. J Clin Pharmacol 49:668-673
    • (2009) J Clin Pharmacol , vol.49 , pp. 668-673
    • Lee, C.Y.1    Chen, H.H.2    Lisy, O.3    Swan, S.4    Cannon, C.5    Lieu, H.D.6    Burnett Jr., J.C.7
  • 29
    • 84886782934 scopus 로고    scopus 로고
    • Correlation of cellular expression with function of NO-sensitive guanylyl cyclase in the murine lower urinary tract
    • Lies B, Groneberg D, Friebe A (2013) Correlation of cellular expression with function of NO-sensitive guanylyl cyclase in the murine lower urinary tract. J Physiol 591:5365-5375
    • (2013) J Physiol , vol.591 , pp. 5365-5375
    • Lies, B.1    Groneberg, D.2    Friebe, A.3
  • 30
  • 31
    • 77950377332 scopus 로고    scopus 로고
    • Cardiac hypertrophy is not amplified by deletion of cGMP-dependent protein kinase I in cardiomyocytes
    • Lukowski R, Rybalkin SD, Loga F, Leiss V, Beavo JA, Hofmann F (2010) Cardiac hypertrophy is not amplified by deletion of cGMP-dependent protein kinase I in cardiomyocytes. Proc Natl Acad Sci U S A 107:5646-5651
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 5646-5651
    • Lukowski, R.1    Rybalkin, S.D.2    Loga, F.3    Leiss, V.4    Beavo, J.A.5    Hofmann, F.6
  • 33
    • 84891490866 scopus 로고    scopus 로고
    • Increased cGMP promotes healthy expansion and browning of white adipose tissue
    • Mitschke MM et al (2013) Increased cGMP promotes healthy expansion and browning of white adipose tissue. FASEB J 2013:9
    • (2013) FASEB J , vol.2013 , pp. 9
    • Mitschke, M.M.1
  • 34
    • 67651094166 scopus 로고    scopus 로고
    • Discovery of riociguat (BAY63-2521): A potent, oral stimulator of soluble guanylate cyclase for the treatment of pulmonary hypertension
    • Mittendorf J et al (2009)Discovery of riociguat (BAY63-2521): a potent, oral stimulator of soluble guanylate cyclase for the treatment of pulmonary hypertension. ChemMedChem 4:853-865
    • (2009) ChemMedChem , vol.4 , pp. 853-865
    • Mittendorf, J.1
  • 35
    • 84899787599 scopus 로고    scopus 로고
    • The effects of super-flux (high performance) dialyzer on plasma glycosylated pro-B-type natriuretic peptide (proBNP) and glycosylated N-terminal proBNP in end-stage renal disease patients on dialysis
    • Nakagawa Y et al (2014) The effects of super-flux (high performance) dialyzer on plasma glycosylated pro-B-type natriuretic peptide (proBNP) and glycosylated N-terminal proBNP in end-stage renal disease patients on dialysis. PLoS One 9:e92314
    • (2014) PLoS One , vol.9
    • Nakagawa, Y.1
  • 36
    • 77950237717 scopus 로고    scopus 로고
    • The changed metabolic world with human brown adipose tissue: Therapeutic visions
    • Nedergaard J, Cannon B (2010) The changed metabolic world with human brown adipose tissue: therapeutic visions. Cell Metab 11:268-272
    • (2010) Cell Metab , vol.11 , pp. 268-272
    • Nedergaard, J.1    Cannon, B.2
  • 37
    • 61349089775 scopus 로고    scopus 로고
    • Association of common variants in NPPA and NPPB with circulating natriuretic peptides and blood pressure
    • Newton-Cheh C et al (2009) Association of common variants in NPPA and NPPB with circulating natriuretic peptides and blood pressure. Nat Genet 41:348-353
    • (2009) Nat Genet , vol.41 , pp. 348-353
    • Newton-Cheh, C.1
  • 39
    • 84856701189 scopus 로고    scopus 로고
    • Single atom substitution in mouse protein kinase G eliminates oxidant sensing to cause hypertension
    • Prysyazhna O, Rudyk O, Eaton P (2012) Single atom substitution in mouse protein kinase G eliminates oxidant sensing to cause hypertension. Nat Med 18:286-290
    • (2012) Nat Med , vol.18 , pp. 286-290
    • Prysyazhna, O.1    Rudyk, O.2    Eaton, P.3
  • 40
    • 84904330850 scopus 로고    scopus 로고
    • Cyclic GMP and protein kinase G control a Src-containing mechanosome in osteoblasts
    • Rangaswami H et al (2010) Cyclic GMP and protein kinase G control a Src-containing mechanosome in osteoblasts. Sci Signal 3:2001423
    • (2010) Sci Signal , vol.3 , pp. 2001423
    • Rangaswami, H.1
  • 41
    • 84875531214 scopus 로고    scopus 로고
    • Effect of phosphodiesterase-5 inhibition on exercise capacity and clinical status in heart failure with preserved ejection fraction: A randomized clinical trial
    • Redfield MM et al (2013) Effect of phosphodiesterase-5 inhibition on exercise capacity and clinical status in heart failure with preserved ejection fraction: a randomized clinical trial. JAMA 309:1268-1277
    • (2013) JAMA , vol.309 , pp. 1268-1277
    • Redfield, M.M.1
  • 42
    • 84866103447 scopus 로고    scopus 로고
    • Guanylyl cyclases A and B are asymmetric dimers that are allosterically activated by ATP binding to the catalytic domain
    • Robinson JW, Potter LR (2012) Guanylyl cyclases A and B are asymmetric dimers that are allosterically activated by ATP binding to the catalytic domain. Sci Signal 5:2003253
    • (2012) Sci Signal , vol.5 , pp. 2003253
    • Robinson, J.W.1    Potter, L.R.2
  • 43
    • 77649130274 scopus 로고    scopus 로고
    • CD-NP, a chimeric natriuretic peptide for the treatment of heart failure
    • Rose RA (2010) CD-NP, a chimeric natriuretic peptide for the treatment of heart failure. Curr 11:349-356
    • (2010) Curr , vol.11 , pp. 349-356
    • Rose, R.A.1
  • 44
    • 84863981193 scopus 로고    scopus 로고
    • Nitroglycerin fails to lower blood pressure in redox-dead Cys42Ser PKG1alpha knock-in mouse
    • Rudyk O, Prysyazhna O, Burgoyne JR, Eaton P (2012) Nitroglycerin fails to lower blood pressure in redox-dead Cys42Ser PKG1alpha knock-in mouse. Circulation 126:287-295
    • (2012) Circulation , vol.126 , pp. 287-295
    • Rudyk, O.1    Prysyazhna, O.2    Burgoyne, J.R.3    Eaton, P.4
  • 46
    • 84856261411 scopus 로고    scopus 로고
    • Genomewide association study using a high-density single nucleotide polymorphism array and case-control design identifies a novel essential hypertension susceptibility locus in the promoter region of endothelial NO synthase
    • Salvi E et al (2012) Genomewide association study using a high-density single nucleotide polymorphism array and case-control design identifies a novel essential hypertension susceptibility locus in the promoter region of endothelial NO synthase. Hypertension 59:248-255
    • (2012) Hypertension , vol.59 , pp. 248-255
    • Salvi, E.1
  • 47
    • 79958128614 scopus 로고    scopus 로고
    • Soluble guanylate cyclase as an emerging therapeutic target in cardiopulmonary disease
    • Stasch JP, Pacher P, Evgenov OV (2011) Soluble guanylate cyclase as an emerging therapeutic target in cardiopulmonary disease. Circulation 123:2263-2273
    • (2011) Circulation , vol.123 , pp. 2263-2273
    • Stasch, J.P.1    Pacher, P.2    Evgenov, O.V.3
  • 49
    • 84892393197 scopus 로고    scopus 로고
    • Bifurcation of axons from cranial sensory neurons is disabled in the absence of Npr2-induced cGMP signaling
    • Ter-Avetisyan G, Rathjen FG, Schmidt H (2014) Bifurcation of axons from cranial sensory neurons is disabled in the absence of Npr2-induced cGMP signaling. J Neurosci 34:737-747
    • (2014) J Neurosci , vol.34 , pp. 737-747
    • Ter-Avetisyan, G.1    Rathjen, F.G.2    Schmidt, H.3
  • 50
    • 84881661965 scopus 로고    scopus 로고
    • Transgenic mice for cGMP imaging
    • Thunemann M et al (2013) Transgenic mice for cGMP imaging. Circ Res 113:365-371
    • (2013) Circ Res , vol.113 , pp. 365-371
    • Thunemann, M.1
  • 51
    • 84856050272 scopus 로고    scopus 로고
    • Pressure-overload-induced subcellular relocalization/oxidation of soluble guanylyl cyclase in the heart modulates enzyme stimulation
    • Tsai EJ et al (2012) Pressure-overload-induced subcellular relocalization/oxidation of soluble guanylyl cyclase in the heart modulates enzyme stimulation. Circ Res 110:295-303
    • (2012) Circ Res , vol.110 , pp. 295-303
    • Tsai, E.J.1
  • 52
    • 84876841559 scopus 로고    scopus 로고
    • Higher-order interactions bridge the nitric oxide receptor and catalytic domains of soluble guanylate cyclase
    • Underbakke ES, Iavarone AT, Marletta MA (2013) Higher-order interactions bridge the nitric oxide receptor and catalytic domains of soluble guanylate cyclase. Proc Natl Acad Sci U S A 110:6777-6782
    • (2013) Proc Natl Acad Sci U S A , vol.110 , pp. 6777-6782
    • Underbakke, E.S.1    Iavarone, A.T.2    Marletta, M.A.3
  • 53
    • 80052362732 scopus 로고    scopus 로고
    • A uroguanylin-GUCY2C endocrine axis regulates feeding in mice
    • Valentino MA et al (2011) A uroguanylin-GUCY2C endocrine axis regulates feeding in mice. J Clin Invest 121:3578-3588
    • (2011) J Clin Invest , vol.121 , pp. 3578-3588
    • Valentino, M.A.1
  • 54
    • 84865209443 scopus 로고    scopus 로고
    • Low myocardial protein kinase G activity in heart failure with preserved ejection fraction
    • van Heerebeek L et al (2012) Low myocardial protein kinase G activity in heart failure with preserved ejection fraction. Circulation 126:830-839
    • (2012) Circulation , vol.126 , pp. 830-839
    • Van Heerebeek, L.1
  • 55
    • 84876545627 scopus 로고    scopus 로고
    • Intracerebroventricular administration of Ctype natriuretic peptide suppresses food intake via activation of the melanocortin system in mice
    • Yamada-Goto N et al (2013) Intracerebroventricular administration of Ctype natriuretic peptide suppresses food intake via activation of the melanocortin system in mice. Diabetes 62:1500-1504
    • (2013) Diabetes , vol.62 , pp. 1500-1504
    • Yamada-Goto, N.1


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