Guanylyl cyclases A and B are asymmetric dimers that are allosterically activated by ATP binding to the catalytic domain

Science Signaling

Volumn 5, Issue 240, 2012, Pages

  Robinson, Jerid W ^a   Potter, Lincoln R ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; DEOXYADENOSINE TRIPHOSPHATE; DEOXYGUANOSINE TRIPHOSPHATE; DIMER; GUANOSINE TRIPHOSPHATE; HOMODIMER; NATRIURETIC FACTOR; NATRIURETIC PEPTIDE RECEPTOR A; NATRIURETIC PEPTIDE RECEPTOR B;

ALLOSTERISM; ARTICLE; BINDING AFFINITY; BINDING SITE; CATALYSIS; CONCENTRATION RESPONSE; CONTROLLED STUDY; HUMAN; HUMAN CELL; MICHAELIS CONSTANT; POINT MUTATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION;

ADENOSINE TRIPHOSPHATE; ALLOSTERIC REGULATION; ALLOSTERIC SITE; ANIMALS; DIMERIZATION; ENZYME ACTIVATION; GUANOSINE TRIPHOSPHATE; HEK293 CELLS; HUMANS; MICE; MODELS, BIOLOGICAL; MUTAGENESIS; NATRIURETIC PEPTIDES; POINT MUTATION; RECEPTORS, ATRIAL NATRIURETIC FACTOR; REGRESSION ANALYSIS; SECOND MESSENGER SYSTEMS;

EID: 84866103447     PISSN: 19450877     EISSN: 19379145     Source Type: Journal    
DOI: 10.1126/scisignal.2003253     Document Type: Article

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