-
2
-
-
0026636441
-
Free radicals, antioxidants and human disease: Where are we now?
-
Halliwell, B., J.M.C.Gutteridge, and C.E. Cross: Free radicals, antioxidants and human disease: Where are we now? J Lab Clin Med 119, 598-620 (1992)
-
(1992)
J Lab Clin Med
, vol.119
, pp. 598-620
-
-
Halliwell, B.1
Gutteridge, J.M.C.2
Cross, C.E.3
-
3
-
-
0005790852
-
Iron chelation in biochemistry and medicine
-
Ed: Rice-Evans C., Rechelieu Press, London
-
Kontoghiorghes, G.J.: Iron chelation in biochemistry and medicine. Ed: Rice-Evans C., Rechelieu Press, London."Free radicals, oxidant stress and drug action". 277-303 (1987)
-
(1987)
Free Radicals, Oxidant Stress and Drug Action
, pp. 277-303
-
-
Kontoghiorghes, G.J.1
-
4
-
-
70350685257
-
Prospects for introducing deferiprone as potent pharmaceutical antioxidant
-
Kontoghiorghes, G.J.: Prospects for introducing deferiprone as potent pharmaceutical antioxidant. Front Biosci (Elite Ed) 1, 161-178 (2009)
-
(2009)
Front Biosci (Elite Ed)
, vol.1
, pp. 161-178
-
-
Kontoghiorghes, G.J.1
-
5
-
-
79957440246
-
Stability and reactivity of free radicals: A physicochemical perspective with biological implications
-
Karogodina, T.Y., S.V.Sergeeva and Stass, D.V.: Stability and reactivity of free radicals: a physicochemical perspective with biological implications. Hemoglobin 35, 262-275(2011)
-
(2011)
Hemoglobin
, vol.35
, pp. 262-275
-
-
Karogodina, T.Y.1
Sergeeva, S.V.2
Stass, D.V.3
-
6
-
-
70350694439
-
Risk/benefit assessment, advantages over other drugs and targeting methods in the use of deferiprone as a pharmaceutical antioxidant in iron loading and non iron loading conditions
-
Kontoghiorghes, G.J., A. Efstathiou, M. Kleanthous, Y. Michaelides and Kolnagou, A: Risk/benefit assessment, advantages over other drugs and targeting methods in the use of deferiprone as a pharmaceutical antioxidant in iron loading and non iron loading conditions. Hemoglobin 33, 386-397 (2009)
-
(2009)
Hemoglobin
, vol.33
, pp. 386-397
-
-
Kontoghiorghes, G.J.1
Efstathiou, A.2
Kleanthous, M.3
Michaelides, Y.4
Kolnagou, A.5
-
7
-
-
0027051555
-
Inhibition of cyclooxygenase and lipoxygenase activity by iron chelators: Possible use in the treatment of eicosanoid-related disorders
-
Jeremy, J.Y., J. Gill, T. Prior, G. Sifakis M.A. Barradas, and G.J. Kontoghiorghes: Inhibition of cyclooxygenase and lipoxygenase activity by iron chelators: Possible use in the treatment of eicosanoid-related disorders. Drugs Today 28 (Suppl A), 35-43 (1992)
-
(1992)
Drugs Today
, vol.28
, Issue.SUPPL. A
, pp. 35-43
-
-
Jeremy, J.Y.1
Gill, J.2
Prior, T.3
Sifakis, G.4
Barradas, M.A.5
Kontoghiorghes, G.J.6
-
8
-
-
84884170817
-
Regulation of circadian clocks by redox homeostasis
-
Epub ahead of print
-
Stangherlin, A. and A.B. Reddy: Regulation of circadian clocks by redox homeostasis. J Biol Chem. (2013) [Epub ahead of print]
-
(2013)
J Biol Chem
-
-
Stangherlin, A.1
Reddy, A.B.2
-
9
-
-
84875744148
-
Glutathione synthesis
-
Lu S.C.: Glutathione synthesis. Biochim Biophys Acta 830, 3143-3153 (2013)
-
(2013)
Biochim Biophys Acta
, vol.830
, pp. 3143-3153
-
-
Lu, S.C.1
-
10
-
-
77956763614
-
Antioxidant and chelating properties of flavonoids
-
Korkina, L.G. and I.B. Afanas'ev: Antioxidant and chelating properties of flavonoids. Adv Pharmacol 38, 151-163. (1997)
-
(1997)
Adv Pharmacol
, vol.38
, pp. 151-163
-
-
Korkina, L.G.1
Afanas'Ev, I.B.2
-
11
-
-
48149095229
-
The flavonoid fisetin promotes nerve cell survival from trophic factor withdrawal by enhancement of proteasome activity
-
Maher P.: The flavonoid fisetin promotes nerve cell survival from trophic factor withdrawal by enhancement of proteasome activity. Arch Biochem Biophys 476, 139-144 (2008)
-
(2008)
Arch Biochem Biophys
, vol.476
, pp. 139-144
-
-
Maher, P.1
-
12
-
-
84860331697
-
Free radicals and antioxidants: Updating a personal view
-
Halliwell, B.: Free radicals and antioxidants: updating a personal view. Nutr Rev 70, 257-265 (2012)
-
(2012)
Nutr Rev
, vol.70
, pp. 257-265
-
-
Halliwell, B.1
-
14
-
-
27744571203
-
Superoxide and nitric oxide in pathological conditions associated with iron overload. The effects of antioxidants and chelators
-
Afanas'ev, I.B.: Superoxide and nitric oxide in pathological conditions associated with iron overload. The effects of antioxidants and chelators. Curr Med Chem 12, 2731-2739 (2005)
-
(2005)
Curr Med Chem
, vol.12
, pp. 2731-2739
-
-
Afanas'Ev, I.B.1
-
15
-
-
0038649860
-
Benefits and risks of deferiprone in iron overload in thalassaemia and other conditions
-
Kontoghiorghes, G.J., K. Neocleous, and A. Kolnagou: Benefits and risks of deferiprone in iron overload in thalassaemia and other conditions. Drug Safety 26, 553-584 (2003)
-
(2003)
Drug Safety
, vol.26
, pp. 553-584
-
-
Kontoghiorghes, G.J.1
Neocleous, K.2
Kolnagou, A.3
-
16
-
-
33745564177
-
Iron mobilization from transferrin and non-transferrin bound iron by deferiprone. Implications in the treatment of thalassaemia, anaemia of chronic disease, cancer and other conditions
-
Kontoghiorghes, G.J.: Iron mobilization from transferrin and non-transferrin bound iron by deferiprone. Implications in the treatment of thalassaemia, anaemia of chronic disease, cancer and other conditions. Hemoglobin 30, 183-200 (2006)
-
(2006)
Hemoglobin
, vol.30
, pp. 183-200
-
-
Kontoghiorghes, G.J.1
-
17
-
-
27744485989
-
Molecular factors and mechanisms affecting iron and other metal excretion or absorption in health and disease. The role of natural and synthetic chelators
-
Kontoghiorghes, G.J., and A. Kolnagou: Molecular factors and mechanisms affecting iron and other metal excretion or absorption in health and disease. The role of natural and synthetic chelators. Curr Med Chem 12, 2695-2709 (2005)
-
(2005)
Curr Med Chem
, vol.12
, pp. 2695-2709
-
-
Kontoghiorghes, G.J.1
Kolnagou, A.2
-
18
-
-
27744491186
-
Essentiality, toxicology and chelation therapy of zinc and copper
-
Cai, L., X.K. Li, Y.Song, and M.G. Cherian: Essentiality, toxicology and chelation therapy of zinc and copper. Curr Med Chem 12, 2753-2763 (2005)
-
(2005)
Curr Med Chem
, vol.12
, pp. 2753-2763
-
-
Cai, L.1
Li, X.K.2
Song, Y.3
Cherian, M.G.4
-
19
-
-
27744544284
-
Advances in iron overload therapies. Prospects for effective use of deferiprone (L1), deferoxamine, the new experimental chelators ICL670, GT56-252, L1NAll and their combination
-
Kontoghiorghes, G.J., E. Eracleous, C. Economides and A. Kolnagou: Advances in iron overload therapies. Prospects for effective use of deferiprone (L1), deferoxamine, the new experimental chelators ICL670, GT56-252, L1NAll and their combination. Curr Med Chem 12, 2663-2681 (2005)
-
(2005)
Curr Med Chem
, vol.12
, pp. 2663-2681
-
-
Kontoghiorghes, G.J.1
Eracleous, E.2
Economides, C.3
Kolnagou, A.4
-
20
-
-
0034014591
-
Ultrastructural pathology of the heart in patients with beta- thalassaemia major
-
Kyriacou, K.Y., Michaelides, R. Senkus, K. Simamonian, N. Pavlides, L. Antoniades, and C. Zambartas: Ultrastructural pathology of the heart in patients with beta- thalassaemia major. Ultrastruct Pathol 24, 75-81 (2000)
-
(2000)
Ultrastruct Pathol
, vol.24
, pp. 75-81
-
-
Kyriacou, K.Y.1
Michaelides2
Senkus, R.3
Simamonian, K.4
Pavlides, N.5
Antoniades, L.6
Zambartas, C.7
-
21
-
-
0017605454
-
Ferritin in human liver cells of homozygous beta-thalassaemia: Ultrastructural observations
-
Iancu, T.C., and H.B. Neustein: Ferritin in human liver cells of homozygous beta-thalassaemia: ultrastructural observations. Br J Haematol 37, 527-535 (1977)
-
(1977)
Br J Haematol
, vol.37
, pp. 527-535
-
-
Iancu, T.C.1
Neustein, H.B.2
-
22
-
-
27744527460
-
Chelators as antidotes of metal toxicity: Therapeutic and experimental aspects
-
Blanusa, M., V.M. Varnai, M Piasek, and K. Kostial: Chelators as antidotes of metal toxicity: therapeutic and experimental aspects. Curr Med Chem 12, 2771-2794 (2005)
-
(2005)
Curr Med Chem
, vol.12
, pp. 2771-2794
-
-
Blanusa, M.1
Varnai, V.M.2
Piasek, M.3
Kostial, K.4
-
23
-
-
27744603887
-
Structure/function overview of proteins involved in iron storage and transport
-
Sargent, P.J., S. Farnaud, and R.W. Evans: Structure/function overview of proteins involved in iron storage and transport. Curr Med Chem 12, 2683-2693 (2005)
-
(2005)
Curr Med Chem
, vol.12
, pp. 2683-2693
-
-
Sargent, P.J.1
Farnaud, S.2
Evans, R.W.3
-
24
-
-
0027195024
-
Competition between deferipone, desferrioxamine and other chelators for iron and the effect of other metals
-
Sheppard, L., and G.J. Kontoghiorghes: Competition between deferipone, desferrioxamine and other chelators for iron and the effect of other metals. Arzheim- Forsch/Drug Res 43:659-663 (1993)
-
(1993)
Arzheim- Forsch/Drug Res
, vol.43
, pp. 659-663
-
-
Sheppard, L.1
Kontoghiorghes, G.J.2
-
25
-
-
0022637547
-
Iron chelation using subcutaneous infusion of diethylene triamine penta-acetic acid (DTPA)
-
Pippard, M.J., M.J. Jackson, K.Hoffman, M. Petrou and C.B. Modell: Iron chelation using subcutaneous infusion of diethylene triamine penta-acetic acid (DTPA) Scand J Haematol 36, 466-472 (1986)
-
(1986)
Scand J Haematol
, vol.36
, pp. 466-472
-
-
Pippard, M.J.1
Jackson, M.J.2
Hoffman, K.3
Petrou, M.4
Modell, C.B.5
-
26
-
-
0023946136
-
Depletion of trace elements and acute occular toxicity induced by desferrioxamine in patients with thalassaemia
-
De Virgilis, S., M.Cognia, M.P. Turco, F.Frau, C.Dessi, F. Argiolou, R. Sorcinelli, A. Sitzia, and A.Cao: Depletion of trace elements and acute occular toxicity induced by desferrioxamine in patients with thalassaemia. Arch Dis Child, 250-255 (1988)
-
(1988)
Arch Dis Child
, pp. 250-255
-
-
De Virgilis, S.1
Cognia, M.2
Turco, M.P.3
Frau, F.4
Dessi, C.5
Argiolou, F.6
Sorcinelli, R.7
Sitzia, A.8
Cao, A.9
-
27
-
-
0028630549
-
Zinc concentration in patients with iron overload receiving oral iron chelator 1,2-dimethyl-3-hydroxypyrid-4-one or desferrioxamine
-
AlRefai, F.N., B.Wonke, D.G. Wickens, Y. Aydinok, A. Fielding, and A.V. Hoffbrand: Zinc concentration in patients with iron overload receiving oral iron chelator 1,2-dimethyl-3-hydroxypyrid-4-one or desferrioxamine. J Clin Pathol 47:657-660 (1994)
-
(1994)
J Clin Pathol
, vol.47
, pp. 657-660
-
-
AlRefai, F.N.1
Wonke, B.2
Wickens, D.G.3
Aydinok, Y.4
Fielding, A.5
Hoffbrand, A.V.6
-
28
-
-
0015102808
-
8-hydroxyquinoline: Chronic toxicity and inhibitory effect on the carcinogenicity of N-2- fluorenylacetamide
-
Yamamoto, R.S., G.M. Williams, H.H. Frangel, and J.H. Weisburger: 8-hydroxyquinoline: chronic toxicity and inhibitory effect on the carcinogenicity of N-2- fluorenylacetamide. Toxicol Appl Pharmacol 19, 687-698 (1971)
-
(1971)
Toxicol Appl Pharmacol
, vol.19
, pp. 687-698
-
-
Yamamoto, R.S.1
Williams, G.M.2
Frangel, H.H.3
Weisburger, J.H.4
-
29
-
-
0023530083
-
Free radical and cytotoxic effects of chelators and their iron complexes in the hepatocyte
-
Mostert, L.J., J.A.L.M. Van Dorst, J.F. Koster, H.G.Van Eijk, and G.J. Kontoghiorghes: Free radical and cytotoxic effects of chelators and their iron complexes in the hepatocyte. Free Rad Res Comms 3: 379-388 (1987)
-
(1987)
Free Rad Res Comms
, vol.3
, pp. 379-388
-
-
Mostert, L.J.1
Van Dorst, J.A.L.M.2
Koster, J.F.3
Van Eijk, H.G.4
Kontoghiorghes, G.J.5
-
30
-
-
0028196693
-
Studies of aluminium mobilisation in renal dialysis patients using the oral chelator 1, 2-dimethyl-3-hydroxypyrid-4-one
-
Kontoghiorghes, G.J., J.Barr, and R.A. Baillod: Studies of aluminium mobilisation in renal dialysis patients using the oral chelator 1, 2-dimethyl-3-hydroxypyrid-4-one. Arzn.Forsch/Drug Res 44: 522-526 (1994)
-
(1994)
Arzn.Forsch/Drug Res
, vol.44
, pp. 522-526
-
-
Kontoghiorghes, G.J.1
Barr, J.2
Baillod, R.A.3
-
31
-
-
0023489829
-
Effective chelation of iron in betathalassaemia with the oral chelator 1, 2-dimethyl-3-hydroxypyrid-4-one
-
Kontoghiorghes, G.J., M.A.Aldouri, A.V. Hoffbrand, J. Barr, B. Wonke, T. Kourouklaris, and L. Sheppard: Effective chelation of iron in betathalassaemia with the oral chelator 1, 2-dimethyl-3-hydroxypyrid-4-one. Br Med J 295: 1509-1512 (1987)
-
(1987)
Br Med J
, vol.295
, pp. 1509-1512
-
-
Kontoghiorghes, G.J.1
Aldouri, M.A.2
Hoffbrand, A.V.3
Barr, J.4
Wonke, B.5
Kourouklaris, T.6
Sheppard, L.7
-
32
-
-
0025669925
-
Chelators affecting iron absorption in mice. Arzn.Forsch
-
Kontoghiorghes, G.J.: Chelators affecting iron absorption in mice. Arzn.Forsch/Drug Res 40, 1332-1335 (1990)
-
(1990)
Drug Res
, vol.40
, pp. 1332-1335
-
-
Kontoghiorghes, G.J.1
-
33
-
-
0022946184
-
In vitro screening of iron chelators using models of free radical damage
-
Kontoghiorghes, G.J., M.I. Jackson, and J. Lunec: In vitro screening of iron chelators using models of free radical damage. Free Rad Res Comms 2: 115-124 (1986)
-
(1986)
Free Rad Res Comms
, vol.2
, pp. 115-124
-
-
Kontoghiorghes, G.J.1
Jackson, M.I.2
Lunec, J.3
-
34
-
-
33745519058
-
Ironchelating and free-radical scavenging activities in microwave processed green tea in iron overload
-
Srichairatanakool, S., S.Ounjaijean, C. Thephinlap, U. Khansuwan, C.Phisalpong, and S. Fuchareon: Ironchelating and free-radical scavenging activities in microwave processed green tea in iron overload. Hemoglobin 30, 311- 327 (2006)
-
(2006)
Hemoglobin
, vol.30
, pp. 311-327
-
-
Srichairatanakool, S.1
Ounjaijean, S.2
Thephinlap, C.3
Khansuwan, U.4
Phisalpong, C.5
Fuchareon, S.6
-
36
-
-
0025569762
-
Design, properties and effective use of the oral chelator L1 and other α- ketohydroxypyridines in the treatment of transfusional iron overload in thalassaemia
-
Kontoghiorghes, G.J.: Design, properties and effective use of the oral chelator L1 and other α- ketohydroxypyridines in the treatment of transfusional iron overload in thalassaemia. Ann NY Acad Sci 612, 339-350 (1990)
-
(1990)
Ann NY Acad Sci
, vol.612
, pp. 339-350
-
-
Kontoghiorghes, G.J.1
-
37
-
-
3242753676
-
The design and development of deferiprone (L1) and other iron chelators for clinical use: Targeting methods and application prospects
-
Kontoghiorghes, G.J., K. Pattichis, K. Neocleous, and A. Kolnagou: The design and development of deferiprone (L1) and other iron chelators for clinical use: Targeting methods and application prospects. Curr Med Chem 11, 2161-2183 (2004)
-
(2004)
Curr Med Chem
, vol.11
, pp. 2161-2183
-
-
Kontoghiorghes, G.J.1
Pattichis, K.2
Neocleous, K.3
Kolnagou, A.4
-
38
-
-
0023275163
-
New synthetic approach and iron chelation studies of 1-alkyl-2-methyl-3- hydroxypyrid-4-ones
-
Kontoghiorghes, G.J., L. Sheppard, and S. Chambers: New synthetic approach and iron chelation studies of 1-alkyl-2-methyl-3-hydroxypyrid-4-ones. Arz.Forsch/Drug Res 37, 1099-1102 (1987)
-
(1987)
Arz.Forsch/Drug Res
, vol.37
, pp. 1099-1102
-
-
Kontoghiorghes, G.J.1
Sheppard, L.2
Chambers, S.3
-
39
-
-
0035664696
-
Molecular factors affecting the complex formation between deferiprone (L1) and Cu (II)
-
Pashalidis, I., and G.J. Kontoghiorghes: Molecular factors affecting the complex formation between deferiprone (L1) and Cu (II) Arz.Forsch/Drug Res 51, 998- 1003 (2001)
-
(2001)
Arz.Forsch/Drug Res
, vol.51
, pp. 998-1003
-
-
Pashalidis, I.1
Kontoghiorghes, G.J.2
-
40
-
-
0032729867
-
Effective complex formation in the interaction of I,2-dimethyl-3- hydroxypyrid-4-one (Deferiprone or L1) with Uranium (VI)
-
Pashalidis, I., and G.J. Kontoghiorghes: Effective complex formation in the interaction of I,2-dimethyl-3-hydroxypyrid-4-one (Deferiprone or L1) with Uranium (VI) J Rad Nuclear Chem 242, 181-184 (1999)
-
(1999)
J Rad Nuclear Chem
, vol.242
, pp. 181-184
-
-
Pashalidis, I.1
Kontoghiorghes, G.J.2
-
41
-
-
0028840530
-
Comparative efficacy and toxicity of desferrioxamine, deferiprone and other iron and aluminium chelating drugs
-
Kontoghiorghes, G.J.: Comparative efficacy and toxicity of desferrioxamine, deferiprone and other iron and aluminium chelating drugs. Toxicol Lett 80, 1-18 (1995)
-
(1995)
Toxicol Lett
, vol.80
, pp. 1-18
-
-
Kontoghiorghes, G.J.1
-
42
-
-
0025007785
-
Pharmacokinetic studies in humans with the oral iron chelator 1, 2-dimethyl-3-hydroxypyrid-4-one
-
Kontoghiorghes, G.J., J.G. Goddard, A.N. Bartlett, and L. Sheppard: Pharmacokinetic studies in humans with the oral iron chelator 1, 2-dimethyl-3-hydroxypyrid-4-one. Clin Pharmacol Therap 48, 255-261 (1990)
-
(1990)
Clin Pharmacol Therap
, vol.48
, pp. 255-261
-
-
Kontoghiorghes, G.J.1
Goddard, J.G.2
Bartlett, A.N.3
Sheppard, L.4
-
43
-
-
0025018222
-
Long term trial with the oral chelator 1, 2-dimethyl-3-hydroxypyrid-4-one (L1) (I) Iron chelation and metabolic studies
-
Kontoghiorghes, G.J., A.N. Bartlett, A.V. Hoffbrand, J.G. Goddard, L.Sheppard, J.Barr, and Nortey P: Long term trial with the oral chelator 1, 2-dimethyl-3-hydroxypyrid-4-one (L1) (I) Iron chelation and metabolic studies. Br J Haematol 76, 295-300 (1990)
-
(1990)
Br J Haematol
, vol.76
, pp. 295-300
-
-
Kontoghiorghes, G.J.1
Bartlett, A.N.2
Hoffbrand, A.V.3
Goddard, J.G.4
Sheppard, L.5
Barr, J.6
Nortey, P.7
-
44
-
-
0029120697
-
Oral iron chelation therapy with deferiprone (L1): Monitoring of biochemical, drug and iron excretion changes
-
Kontoghiorghes, G.J., A.N. Bartlett, L. Sheppard, J. Barr, and P. Nortey: Oral iron chelation therapy with deferiprone (L1): Monitoring of biochemical, drug and iron excretion changes. Arzn. Forsch/Drug Res 45:65-69 (1995)
-
(1995)
Arzn. Forsch/Drug Res
, vol.45
, pp. 65-69
-
-
Kontoghiorghes, G.J.1
Bartlett, A.N.2
Sheppard, L.3
Barr, J.4
Nortey, P.5
-
45
-
-
0027056363
-
Synthesis and metabolism of L1 and other novel alphaketohydroxypyridine iron chelators and their metal complexes
-
Sheppard, L., and G.J. Kontoghiorghes: Synthesis and metabolism of L1 and other novel alphaketohydroxypyridine iron chelators and their metal complexes. Drugs Today 28 (Suppl A): 3-10 (1992)
-
(1992)
Drugs Today
, vol.28
, Issue.SUPPL. A
, pp. 3-10
-
-
Sheppard, L.1
Kontoghiorghes, G.J.2
-
46
-
-
0026001164
-
Relationship between the pharmacokinetics and iron excretion pharmacodynamics of the new oral iron chelator1,2-dimethyl-3-hydroxypyrid-4-one in patients with thalassaemia
-
Matsui, D., J. Klein, C. Hermann, V. Grunau, R. McClelland, D. Chung, P. StLouis, N. Olivieri, and G. Koren: Relationship between the pharmacokinetics and iron excretion pharmacodynamics of the new oral iron chelator1,2-dimethyl-3- hydroxypyrid-4-one in patients with thalassaemia. Clin Pharmacol Therap 50, 294-298 (1991)
-
(1991)
Clin Pharmacol Therap
, vol.50
, pp. 294-298
-
-
Matsui, D.1
Klein, J.2
Hermann, C.3
Grunau, V.4
McClelland, R.5
Chung, D.6
StLouis, P.7
Olivieri, N.8
Koren, G.9
-
47
-
-
0027056364
-
The iron-decorporating effect of L1 in normal and TMH-ferrocene iron loaded rats and in one patient with post-transfusional siderosis as judged by 59Fe-labelling technique
-
Nielsen, P., M. Frtjes, B. Drescow, R. Fischer, R. Engelhardt, and H.C. Heinrich: The iron-decorporating effect of L1 in normal and TMH-ferrocene iron loaded rats and in one patient with post-transfusional siderosis as judged by 59Fe-labelling technique. Drugs Today 28 (suppl.A): 45-53 (1992)
-
(1992)
Drugs Today
, vol.28
, Issue.SUPPL.A
, pp. 45-53
-
-
Nielsen, P.1
Frtjes, M.2
Drescow, B.3
Fischer, R.4
Engelhardt, R.5
Heinrich, H.C.6
-
48
-
-
0033025760
-
An investigation into variability in the therapeutic response to deferiprone in patients with thalassaemia major
-
Diav-Citrin, O., G. Atanackovic, and G. Koren: An investigation into variability in the therapeutic response to deferiprone in patients with thalassaemia major. Therap Drug Monitor 21, 74-81 (1999)
-
(1999)
Therap Drug Monitor
, vol.21
, pp. 74-81
-
-
Diav-Citrin, O.1
Atanackovic, G.2
Koren, G.3
-
49
-
-
0035107231
-
Clinical use, therapeutic aspects and future potential of deferiprone in thalassaemia and other conditions of iron and other metal toxicity
-
Kontoghiorghes, G.J.: Clinical use, therapeutic aspects and future potential of deferiprone in thalassaemia and other conditions of iron and other metal toxicity. Drugs Today 37, 23-35 (2001)
-
(2001)
Drugs Today
, vol.37
, pp. 23-35
-
-
Kontoghiorghes, G.J.1
-
50
-
-
0027080322
-
The effect of alphaketohydroxypyridine chelators on transferrin saturation in vitro and in vivo
-
Evans, R.W., M. Sharma, W. Ogwang, K.J. Patel, A.N. Bartlett, and G.J. Kontoghiorghes: The effect of alphaketohydroxypyridine chelators on transferrin saturation in vitro and in vivo. Drugs Today. 28 (Suppl A), 19-23 (1992)
-
(1992)
Drugs Today
, vol.28
, Issue.SUPPL. A
, pp. 19-23
-
-
Evans, R.W.1
Sharma, M.2
Ogwang, W.3
Patel, K.J.4
Bartlett, A.N.5
Kontoghiorghes, G.J.6
-
51
-
-
0028862502
-
Liver iron stores in patients with secondary haemochromatosis under iron chelation therapy with deferoxamine or deferiprone
-
Nielsen, P., R. Fischer, R. Engelhardt, P. Tondury, E.E. Gabbe, and G.E. Janka: Liver iron stores in patients with secondary haemochromatosis under iron chelation therapy with deferoxamine or deferiprone. Br J Haematol 9, 827-833 (1995)
-
(1995)
Br J Haematol
, vol.9
, pp. 827-833
-
-
Nielsen, P.1
Fischer, R.2
Engelhardt, R.3
Tondury, P.4
Gabbe, E.E.5
Janka, G.E.6
-
52
-
-
0026680591
-
Reduction of tissue iron stores and normalisation of serum ferritin during treatment with the oral iron chelator L1 in thalassaemia intermedia
-
Olivieri, N.F., G. Koren, D. Matsui, P.P. Liu, L. Blendy, R. Cameron, R.A. McClelland, D. and M. Templeton: Reduction of tissue iron stores and normalisation of serum ferritin during treatment with the oral iron chelator L1 in thalassaemia intermedia. Blood 79, 2741-2748 (1992)
-
(1992)
Blood
, vol.79
, pp. 2741-2748
-
-
Olivieri, N.F.1
Koren, G.2
Matsui, D.3
Liu, P.P.4
Blendy, L.5
Cameron, R.6
McClelland, R.A.7
Templeton, D.M.8
-
53
-
-
0037125595
-
Comparison of effects of oral deferiprone and subcutaneous desferrioxamine on myocardial iron concentrations and ventricular function in beta-thalassaemia
-
Anderson, L.J., B. Wonke, E. Prescott, S. Holden, J.M. Walker, and D.J. Pennel: Comparison of effects of oral deferiprone and subcutaneous desferrioxamine on myocardial iron concentrations and ventricular function in beta-thalassaemia. Lancet 360, 516-520 (2002)
-
(2002)
Lancet
, vol.360
, pp. 516-520
-
-
Anderson, L.J.1
Wonke, B.2
Prescott, E.3
Holden, S.4
Walker, J.M.5
Pennel, D.J.6
-
54
-
-
7944221912
-
Prophylactic use of deferiprone (L1) and magnetic resonance imaging T2&z.Ast; or T2 for preventing heart disease in thalassaemia
-
Kolnagou, A., Ch. Fessas, A. Papatryphonas, Ch. Economides, and G.J. Kontoghiorghes: Prophylactic use of deferiprone (L1) and magnetic resonance imaging T2&z.ast; or T2 for preventing heart disease in thalassaemia. Br J Haematol 127, 360-361 (2004)
-
(2004)
Br J Haematol
, vol.127
, pp. 360-361
-
-
Kolnagou, A.1
Fessas, Ch.2
Papatryphonas, A.3
Economides, Ch.4
Kontoghiorghes, G.J.5
-
55
-
-
0031848963
-
Effect of oral iron chelator L1 in iron absorption in man
-
Dresow, B., R. Fischer, P. Nielsen, E.E. Gabbe, and A. Piga: Effect of oral iron chelator L1 in iron absorption in man. Ann N Y Acad Sci 850, 466-468 (1998)
-
(1998)
Ann N Y Acad Sci
, vol.850
, pp. 466-468
-
-
Dresow, B.1
Fischer, R.2
Nielsen, P.3
Gabbe, E.E.4
Piga, A.5
-
56
-
-
0037579319
-
Differentiation of the therapeutic and toxicological effects of iron and copper chelating drugs in relation to free radical toxicity
-
Kontoghiorghes, G.J., T. Bunce, and K.R. Bruckdorfer: Differentiation of the therapeutic and toxicological effects of iron and copper chelating drugs in relation to free radical toxicity. Toxicol Lett 78, 48-49 (1995)
-
(1995)
Toxicol Lett
, vol.78
, pp. 48-49
-
-
Kontoghiorghes, G.J.1
Bunce, T.2
Bruckdorfer, K.R.3
-
57
-
-
0031425503
-
Salivary measurement of deferiprone concentrations and correlation with serum levels
-
Pope, E., M. Berkovitch, J. Klein, F. Fassos, and G. Koren: Salivary measurement of deferiprone concentrations and correlation with serum levels. Ther Drug Monitor 19, 95-97 (1997)
-
(1997)
Ther Drug Monitor
, vol.19
, pp. 95-97
-
-
Pope, E.1
Berkovitch, M.2
Klein, J.3
Fassos, F.4
Koren, G.5
-
58
-
-
0024401997
-
Agranulocytosis and thrombocytopenia in a patient with Blackfan-Diamond anaemia during oral chelator trial
-
Hoffbrand, A.V., A. Bartlett, P.A.Veys, N.T.J. O'Connor, and G.J. Kontoghiorghes: Agranulocytosis and thrombocytopenia in a patient with Blackfan-Diamond anaemia during oral chelator trial. Lancet II: 457 (1989)
-
(1989)
Lancet
, vol.2
, pp. 457
-
-
Hoffbrand, A.V.1
Bartlett, A.2
Veys, P.A.3
O'Connor, N.T.J.4
Kontoghiorghes, G.J.5
-
59
-
-
0031011172
-
Deferiprone-induced agranulocytosis: A critical review of five rechallenged cases
-
Loebstein, R., O. Diav-Citrin, and G. Atanackovic: Deferiprone-induced agranulocytosis: a critical review of five rechallenged cases. Clin Drug Invest 13,345-349 (1997)
-
(1997)
Clin Drug Invest
, vol.13
, pp. 345-349
-
-
Loebstein, R.1
Diav-Citrin, O.2
Atanackovic, G.3
-
60
-
-
0024403012
-
Prospects for effective oral iron chelation therapy in man with 1,2-dimethyl-3-hydroxypyrid-4-one and other alphaketohydroxypyridines
-
Kontoghiorghes, G.J., A.H. Bartlett, and A.V. Hoffbrand: Prospects for effective oral iron chelation therapy in man with 1,2-dimethyl-3-hydroxypyrid-4- one and other alphaketohydroxypyridines. Prog Clin Biol Res 309, 107-114 (1989)
-
(1989)
Prog Clin Biol Res
, vol.309
, pp. 107-114
-
-
Kontoghiorghes, G.J.1
Bartlett, A.H.2
Hoffbrand, A.V.3
-
61
-
-
0027053573
-
Long term assessment of efficacy and toxicity of L1 (1,2-dimethyl-3- hydroxypyrid-4-one) in transfusion dependent thalassaemia: Indian trial
-
Agarwal, M.B., S.S.Gupta, C. Viswanathan, D. Vasandani, J. Ramanathan, N. Desai, R.R.Puniyani, and A.T. Chhablani: Long term assessment of efficacy and toxicity of L1 (1,2-dimethyl-3-hydroxypyrid-4-one) in transfusion dependent thalassaemia: Indian trial. Drugs Today, 28 (Suppl A) 107-114 (1992)
-
(1992)
Drugs Today
, vol.28
, Issue.SUPPL. A
, pp. 107-114
-
-
Agarwal, M.B.1
Gupta, S.S.2
Viswanathan, C.3
Vasandani, D.4
Ramanathan, J.5
Desai, N.6
Puniyani, R.R.7
Chhablani, A.T.8
-
62
-
-
0034094839
-
Safety profile of the oral iron chelator deferiprone: A multicentre study
-
Cohen, A.R., R. Galanello, A. Piga, A. Di Palma, C. Voullo, and F. Tricta: Safety profile of the oral iron chelator deferiprone: a multicentre study. Br J Haematol 108, 305-312 (2000)
-
(2000)
Br J Haematol
, vol.108
, pp. 305-312
-
-
Cohen, A.R.1
Galanello, R.2
Piga, A.3
Di Palma, A.4
Voullo, C.5
Tricta, F.6
-
63
-
-
34248635452
-
Fatal agranulocytosis after deferiprone therapy in a child with Diamond-Blackfan anemia
-
Henter, J.I., and J.Karlen: Fatal agranulocytosis after deferiprone therapy in a child with Diamond-Blackfan anemia. Blood 109, 5157-5159 (2007)
-
(2007)
Blood
, vol.109
, pp. 5157-5159
-
-
Henter, J.I.1
Karlen, J.2
-
64
-
-
0036148173
-
Effects on Mycobacterium avium replication in normal human macrophages by deferiprone (L1) and other iron chelators. Possible implications on toxicity
-
Douvas, S.G., M.H. May, A. Kolnagou, and G.J. Kontoghiorghes: Effects on Mycobacterium avium replication in normal human macrophages by deferiprone (L1) and other iron chelators. Possible implications on toxicity. Arzn.Forsch/Drug Res 52, 45-52 (2002)
-
(2002)
Arzn.Forsch/Drug Res
, vol.52
, pp. 45-52
-
-
Douvas, S.G.1
May, M.H.2
Kolnagou, A.3
Kontoghiorghes, G.J.4
-
65
-
-
27744458259
-
Hemoglobin and myoglobin associated oxidative stress: From molecular mechanisms to disease states
-
Reeder, B.J., and M.T. Wilson: Hemoglobin and myoglobin associated oxidative stress: from molecular mechanisms to disease states. Curr Med Chem 12, 2741- 2751 (2005)
-
(2005)
Curr Med Chem
, vol.12
, pp. 2741-2751
-
-
Reeder, B.J.1
Wilson, M.T.2
-
66
-
-
0020110270
-
Kinetic studies on the reduction of cytochrome c. Reaction with dihydroxyconjugated compounds (catechols and quinols)
-
Saleem, M.M., and M.T.Wilson: Kinetic studies on the reduction of cytochrome c. Reaction with dihydroxyconjugated compounds (catechols and quinols) Biochem J 20, 433-444 (1982)
-
(1982)
Biochem J
, vol.20
, pp. 433-444
-
-
Saleem, M.M.1
Wilson, M.T.2
-
67
-
-
0023611979
-
Orally active á-ketohydroxypyridine iron chelators. Effects on iron and other metal mobilisations
-
Kontoghiorghes, G.J.: Orally active á-ketohydroxypyridine iron chelators. Effects on iron and other metal mobilisations. Acta Haematol 78, 212-236 (1987)
-
(1987)
Acta Haematol
, vol.78
, pp. 212-236
-
-
Kontoghiorghes, G.J.1
-
68
-
-
0035894070
-
Iron complexes of deferiprone and dietary plant catechols as cytoprotective superoxide radical scavengers
-
Moridani, M.Y., and P.J. O'Brien: Iron complexes of deferiprone and dietary plant catechols as cytoprotective superoxide radical scavengers. Biochem Pharmacol 62, 1579-1585 (2001)
-
(2001)
Biochem Pharmacol
, vol.62
, pp. 1579-1585
-
-
Moridani, M.Y.1
O'Brien, P.J.2
-
69
-
-
0033999708
-
Deferiprone (L1) induced conformation change of hemoglobin: A fluorescence and CD spectroscopic study
-
Chakraborty, D., and M. Bhattacharrya: Deferiprone (L1) induced conformation change of hemoglobin: A fluorescence and CD spectroscopic study. Mol Cell Biochem 204, 17-20 (2000)
-
(2000)
Mol Cell Biochem
, vol.204
, pp. 17-20
-
-
Chakraborty, D.1
Bhattacharrya, M.2
-
70
-
-
0033694227
-
L1 effects on reactive oxygen (ROS) and nitrogen species (RNS) release, haemoglobin oxidation, low molecular weight antioxidants, and antioxidant enzyme activities in red and white blood cells of thalassaemic patients
-
Korkina, L., C. De Luca, I. Deeva, S. Perrota, B. Nobili, P.Passi, and P. Puddui : L1 effects on reactive oxygen (ROS) and nitrogen species (RNS) release, haemoglobin oxidation, low molecular weight antioxidants, and antioxidant enzyme activities in red and white blood cells of thalassaemic patients. Transfus Sc 23, 253-254 (2000)
-
(2000)
Transfus Sc
, vol.23
, pp. 253-254
-
-
Korkina, L.1
De Luca, C.2
Deeva, I.3
Perrota, S.4
Nobili, B.5
Passi, P.6
Puddui, P.7
-
71
-
-
0037082349
-
Iron regulation of hepatic macrophage TNFalpha expression
-
Tsukamoto, H.: Iron regulation of hepatic macrophage TNFalpha expression. Free Radic Biol Med 32, 309-313 (2002)
-
(2002)
Free Radic Biol Med
, vol.32
, pp. 309-313
-
-
Tsukamoto, H.1
-
72
-
-
0024402583
-
Prevention of postischemic cardiac injury by the orally active iron chelator 1,2-dimethyl-3-hydroxy-4-pyridone (L1) and the antioxidant (+)-cyanidanol-3
-
Van, A.M.M., der Kraaij, H.G.Van Eijk, and J.F. Koster: Prevention of postischemic cardiac injury by the orally active iron chelator 1,2-dimethyl-3-hydroxy-4-pyridone (L1) and the antioxidant (+)-cyanidanol-3. Circulation 80,158-164 (1989)
-
(1989)
Circulation
, vol.80
, pp. 158-164
-
-
Van, A.M.M.1
Der Kraaij2
Van Eijk, H.G.3
Koster, J.F.4
-
73
-
-
0037098878
-
Deferiprone protects against doxorubicin-induced myocyte cytotoxicity
-
Barnabe, N., J.A. Zastre, S. Venkataram, and B.B. Hassinof.: Deferiprone protects against doxorubicin-induced myocyte cytotoxicity. Free Rad Biol Med 33, 266-275 (2002)
-
(2002)
Free Rad Biol Med
, vol.33
, pp. 266-275
-
-
Barnabe, N.1
Zastre, J.A.2
Venkataram, S.3
Hassinof, B.B.4
-
75
-
-
0023821040
-
The iron chelators desferrioxamine and 1-alkyl-methyl-3-hydroxypyrid-4- ones inhibit vascular prostacylin synthesis in vitro
-
Jeremy, J.Y., G.J.Kontoghiorghes, A.V. Hoffbrand, and P. Dandona: The iron chelators desferrioxamine and 1-alkyl-methyl-3-hydroxypyrid-4-ones inhibit vascular prostacylin synthesis in vitro. Biochem J. 254, 239-244 (1988)
-
(1988)
Biochem J
, vol.254
, pp. 239-244
-
-
Jeremy, J.Y.1
Kontoghiorghes, G.J.2
Hoffbrand, A.V.3
Dandona, P.4
-
76
-
-
0024503575
-
Iron chelators inhibit human platelet aggregation, thromboxane A synthesis and lipoxygenase activity
-
Barradas, M.A., J.Jeremy, G.J. Kontoghiorghes, D.P.Michailidis, A.V.Hoffbrand, and P. Dandona: Iron chelators inhibit human platelet aggregation, thromboxane A synthesis and lipoxygenase activity. FEBS Lett 245,105-109 (1989)
-
(1989)
FEBS Lett
, vol.245
, pp. 105-109
-
-
Barradas, M.A.1
Jeremy, J.2
Kontoghiorghes, G.J.3
Michailidis, D.P.4
Hoffbrand, A.V.5
Dandona, P.6
-
77
-
-
0028321696
-
The oral iron chelator, 1,2-dimethyl-3-hydroxypyrid-4-one reduces hepatic-free iron, lipid peroxidation and fat accumulation in chronically ethanol-fed rats
-
Sadrzadeh, S.M., A.A.Nanji, and P.L. Price: The oral iron chelator, 1,2-dimethyl-3-hydroxypyrid-4-one reduces hepatic-free iron, lipid peroxidation and fat accumulation in chronically ethanol-fed rats. J Pharmacol Exp Ther 269, 632-636 (1994)
-
(1994)
J Pharmacol Exp Ther
, vol.269
, pp. 632-636
-
-
Sadrzadeh, S.M.1
Nanji, A.A.2
Price, P.L.3
-
78
-
-
0029081605
-
Action of reactive oxygen species and their antagonists on twitch tension of the rat phrenic nervediaphragm
-
Crosland, R.D.: Action of reactive oxygen species and their antagonists on twitch tension of the rat phrenic nervediaphragm. Pharmacol Toxicol 77, 231-237 (1995)
-
(1995)
Pharmacol Toxicol
, vol.77
, pp. 231-237
-
-
Crosland, R.D.1
-
79
-
-
0030780828
-
Systemic administration of the iron chelator deferiprone attenuates subarachnoid hemorrhage induced cerebral vasospasm in the rabbit
-
Arthur, A.S., A.H. Fergus, G. Lanzino, J. Mathys, N.F. Kassell, and K.S. Lee: Systemic administration of the iron chelator deferiprone attenuates subarachnoid hemorrhage induced cerebral vasospasm in the rabbit. Neurosurgery 41,1385-1391 (1997)
-
(1997)
Neurosurgery
, vol.41
, pp. 1385-1391
-
-
Arthur, A.S.1
Fergus, A.H.2
Lanzino, G.3
Mathys, J.4
Kassell, N.F.5
Lee, K.S.6
-
80
-
-
0033228705
-
Deferiprone, an oral iron chelator, ameliorates experimental colitis and gastric ulceration in rats
-
Ablin, J., O. Shalev, E. Okon, F. Karmeli and D. Rachmilewitz: Deferiprone, an oral iron chelator, ameliorates experimental colitis and gastric ulceration in rats. Inflamm Bowel Dis 5, 253-261 (1999)
-
(1999)
Inflamm Bowel Dis
, vol.5
, pp. 253-261
-
-
Ablin, J.1
Shalev, O.2
Okon, E.3
Karmeli, F.4
Rachmilewitz, D.5
-
81
-
-
84865257014
-
Preventive therapy of experimental colitis with selected iron chelators and anti-oxidants
-
Minaiyan, M., Mostaghel E, and Mahzouni P: Preventive therapy of experimental colitis with selected iron chelators and anti-oxidants. Int J Prev Med. 3, S162-9 (2012)
-
(2012)
Int J Prev Med
, vol.3
-
-
Minaiyan, M.1
Mostaghel, E.2
Mahzouni, P.3
-
82
-
-
0027175998
-
Inhibition of catechol-O-methyltransferase (COMT) as well as tyrosine and tryptophan hydroxylase by the orally active iron chelator, 1,2-dimethyl-3- hydroxypyridin-4-one (L1, CP20), in rat brain in vivo
-
Waldmeier, P.C., A. M. Buchle, and A.F. Steulet: Inhibition of catechol-O-methyltransferase (COMT) as well as tyrosine and tryptophan hydroxylase by the orally active iron chelator, 1,2-dimethyl-3-hydroxypyridin-4- one (L1, CP20), in rat brain in vivo. Biochem Pharmacol 45, 2417-2424 (1993)
-
(1993)
Biochem Pharmacol
, vol.45
, pp. 2417-2424
-
-
Waldmeier, P.C.1
Buchle, A.M.2
Steulet, A.F.3
-
83
-
-
0037051144
-
The influence of deferiprone (L1) and deferoxamine on iron and essential element tissue level and parameters of oxidative status in dietary iron-loaded mice
-
Eybl, V., D. Kotyzova, M. Kolek, J. Koutensky, and P. Nielsen: The influence of deferiprone (L1) and deferoxamine on iron and essential element tissue level and parameters of oxidative status in dietary iron-loaded mice. Toxicol Lett 128, 169-175 (2002)
-
(2002)
Toxicol Lett
, vol.128
, pp. 169-175
-
-
Eybl, V.1
Kotyzova, D.2
Kolek, M.3
Koutensky, J.4
Nielsen, P.5
-
84
-
-
0026306055
-
Influence of iron chelators, 1,2-dialkyl-3-hydroxypyridin-4-ones, on the lipid peroxidation and glutathione level in the liver of mice
-
Eybl, V., D. Caisová J. Koutenský, and G.J. Kontoghiorghes: Influence of iron chelators, 1,2-dialkyl-3-hydroxypyridin-4-ones, on the lipid peroxidation and glutathione level in the liver of mice. Arch Toxicol Suppl 14,185-187(1991)
-
(1991)
Arch Toxicol Suppl
, vol.14
, pp. 185-187
-
-
Eybl, V.1
Caisová, D.2
Koutenský, J.3
Kontoghiorghes, G.J.4
-
85
-
-
77953264669
-
The effect of iron (III) on the activity of selenoenzymes and oxidative damage in the liver of rats. Interaction with natural antioxidants and deferiprone
-
Hodková, A., P. Cerná, D. Kotyzová, and V.Eybl: The effect of iron (III) on the activity of selenoenzymes and oxidative damage in the liver of rats. Interaction with natural antioxidants and deferiprone. Hemoglobin 34:278-283 (2010)
-
(2010)
Hemoglobin
, vol.34
, pp. 278-283
-
-
Hodková, A.1
Cerná, P.2
Kotyzová, D.3
Eybl, V.4
-
86
-
-
2442448514
-
Magnetic-field-induced DNA strand breaks in brain cells of the rat
-
Lai, H., and N.P. Singh: Magnetic-field-induced DNA strand breaks in brain cells of the rat. Environ Health Perspect 112, A726 (2004)
-
(2004)
Environ Health Perspect
, vol.112
-
-
Lai, H.1
Singh, N.P.2
-
87
-
-
33748968521
-
Deferiprone protects the isolated atria from cardiotoxicity induced by doxorubicin
-
Xu, L.J., L.Jin, H. Pan, A.Z., G. Wei P.P. Li and W.Y.Lu: Deferiprone protects the isolated atria from cardiotoxicity induced by doxorubicin. Acta Pharmacol Sin 27, 1333-1339 (2006)
-
(2006)
Acta Pharmacol Sin
, vol.27
, pp. 1333-1339
-
-
Xu, L.J.1
Jin, L.2
Pan, H.3
Z, A.4
Wei, G.5
Li, P.P.6
Lu, W.Y.7
-
88
-
-
79957523019
-
The effect of the oral iron chelator deferiprone on the liver damage induced by tamoxifen in female rats
-
Cerná, P., D. Kotyzová, and V. Eybl: The effect of the oral iron chelator deferiprone on the liver damage induced by tamoxifen in female rats. Hemoglobin 35, 255-261(2011)
-
(2011)
Hemoglobin
, vol.35
, pp. 255-261
-
-
Cerná, P.1
Kotyzová, D.2
Eybl, V.3
-
89
-
-
39549114148
-
Deferiprone, an orally deliverable iron chelator, ameliorates experimental autoimmune encephalomyelitis
-
Mitchell, K.M., A.L. Dotson, K.M. Cool, A. Chakraparty, S. H. Benedict, and S. M. Levine: Deferiprone, an orally deliverable iron chelator, ameliorates experimental autoimmune encephalomyelitis. Mult Scler 13, 1118-1126 (2007)
-
(2007)
Mult Scler
, vol.13
, pp. 1118-1126
-
-
Mitchell, K.M.1
Dotson, A.L.2
Cool, K.M.3
Chakraparty, A.4
Benedict, S.H.5
Levine, S.M.6
-
90
-
-
37749054933
-
Effect of an oral iron chelator or iron-deficient diets on uroporphyria in a murine model of porphyria cutanea tarda
-
Gorman, N., A. Zaharia, H. S. Trask, J.G. Szakacs, N.J. Jacobs, J.M.Jacobs, D. Balestra, J.F.Sinclair, and P.R. Sinclair: Effect of an oral iron chelator or iron-deficient diets on uroporphyria in a murine model of porphyria cutanea tarda. Hepatology 46,1927-1034 (2007)
-
(2007)
Hepatology
, vol.46
, pp. 1927-11034
-
-
Gorman, N.1
Zaharia, A.2
Trask, H.S.3
Szakacs, J.G.4
Jacobs, N.J.5
Jacobs, J.M.6
Balestra, D.7
Sinclair, J.F.8
Sinclair, P.R.9
-
91
-
-
0031277617
-
Iron and atherosclerosis: Inhibition by the iron chelator deferiprone (L1)
-
Matthews, A.J., G.M. Vercellotti, H.J. Menchaca, P.H. Bloch, V.N.Michalek P.H. Marker, J.Murarand, and H. Buchwald: Iron and atherosclerosis: Inhibition by the iron chelator deferiprone (L1) J Surg Res 73, 35-40 (1997)
-
(1997)
J Surg Res
, vol.73
, pp. 35-40
-
-
Matthews, A.J.1
Vercellotti, G.M.2
Menchaca, H.J.3
Bloch, P.H.4
Michalek, V.N.5
Marker, P.H.6
Murarand, J.7
Buchwald, H.8
-
92
-
-
84878128952
-
Wound healing by topical application of antioxidant iron chelators: Kojic acid and deferiprone
-
Mohammadpour, M., M. Behjati, A. Sadeghi, and A. Fassihi: Wound healing by topical application of antioxidant iron chelators: kojic acid and deferiprone. Int Wound J. 10, 260-264 (2013)
-
(2013)
Int Wound J
, vol.10
, pp. 260-264
-
-
Mohammadpour, M.1
Behjati, M.2
Sadeghi, A.3
Fassihi, A.4
-
93
-
-
77952096923
-
Copper (II)-selective chelation improves function and antioxidant defences in cardiovascular tissues of rats as a model of diabetes: Comparisons between triethylenetetramine and three less copper-selective transition-metal-targeted treatments
-
Lu, J., D. Gong, S.Y. Choong, H. Xu, Y.K. Chan, X. Chen, S. Fitzpatrick, S. Glyn-Jones, S. Zhang, T. Nakamura, K. Ruggiero, V. Obolonkin, S.D. Poppitt, A.R. Phillips, and G.J. Cooper: Copper (II)-selective chelation improves function and antioxidant defences in cardiovascular tissues of rats as a model of diabetes: comparisons between triethylenetetramine and three less copper-selective transition-metal-targeted treatments. Diabetologia 53,1217-1226 (2010)
-
(2010)
Diabetologia
, vol.53
, pp. 1217-1226
-
-
Lu, J.1
Gong, D.2
Choong, S.Y.3
Xu, H.4
Chan, Y.K.5
Chen, X.6
Fitzpatrick, S.7
Glyn-Jones, S.8
Zhang, S.9
Nakamura, T.10
Ruggiero, K.11
Obolonkin, V.12
Poppitt, S.D.13
Phillips, A.R.14
Cooper, G.J.15
-
94
-
-
0029022458
-
Copper chelators inhibit platelet thromboxane A2 synthesis and lipoxygenase activity in vitro
-
Jeremy, J.Y., J. Gill and G.J. Kontoghiorghes: Copper chelators inhibit platelet thromboxane A2 synthesis and lipoxygenase activity in vitro. J Dr Dev Clin Prac 7, 119-121(1995)
-
(1995)
J Dr Dev Clin Prac
, vol.7
, pp. 119-121
-
-
Jeremy, J.Y.1
Gill, J.2
Kontoghiorghes, G.J.3
-
95
-
-
27744441891
-
Quantitative evaluation of oxidative stress status on peripheral blood in beta-thalassaemic patients by means of electron paramagnetic resonance spectroscopy
-
Filosa, A., L. Valgimigli, G.F. Pedulli, A. Sapone, A. Maggio, D. Renda, C. Scazzone, R. Malizia, L. Pitrolo, C. Lo Pinto, Z. Borsellino, L. Cuccia, M. Capra, D. Canistro, M. Broccoli, A. Soleti, and M. Paolini: Quantitative evaluation of oxidative stress status on peripheral blood in beta-thalassaemic patients by means of electron paramagnetic resonance spectroscopy. Br J Haematol.13,135-140 (2005)
-
(2005)
Br J Haematol
, vol.13
, pp. 135-140
-
-
Filosa, A.1
Valgimigli, L.2
Pedulli, G.F.3
Sapone, A.4
Maggio, A.5
Renda, D.6
Scazzone, C.7
Malizia, R.8
Pitrolo, L.9
Lo Pinto, C.10
Borsellino, Z.11
Cuccia, L.12
Capra, M.13
Canistro, D.14
Broccoli, M.15
Soleti, A.16
Paolini, M.17
-
96
-
-
0023214937
-
1, 2- Dimethyl-3-hydroxypyrid-4-one, on orally active chelator for the treatment of transfusional iron overload
-
Kontoghiorghes, G.J., M.A.Aldouri, L.N.Sheppard, and A.V. Hoffbrand: 1, 2- Dimethyl-3-hydroxypyrid-4-one, on orally active chelator for the treatment of transfusional iron overload. Lancet I, 1294-1295 (1987)
-
(1987)
Lancet
, vol.1
, pp. 1294-1295
-
-
Kontoghiorghes, G.J.1
Aldouri, M.A.2
Sheppard, L.N.3
Hoffbrand, A.V.4
-
97
-
-
33745531237
-
Effective combination therapy of deferiprone and deferoxamine for the rapid clearance of excess cardiac iron and prevention of heart disease in thalassaemia. The protocol of the international committee on oral chelators
-
Kolnagou, A., and G.J. Kontoghiorghes: Effective combination therapy of deferiprone and deferoxamine for the rapid clearance of excess cardiac iron and prevention of heart disease in thalassaemia. The protocol of the international committee on oral chelators. Hemoglobin 30, 239-249 (2006)
-
(2006)
Hemoglobin
, vol.30
, pp. 239-249
-
-
Kolnagou, A.1
Kontoghiorghes, G.J.2
-
98
-
-
84876249878
-
Potential clinical applications of chelating drugs in diseases targeting transferrin-bound iron and other metals
-
Kontoghiorghe, C.N., Kolnagou, A., and G.J. Kontoghiorghes. Potential clinical applications of chelating drugs in diseases targeting transferrin-bound iron and other metals. Expert Opin Investig Drugs 22, 591-618 (2013)
-
(2013)
Expert Opin Investig Drugs
, vol.22
, pp. 591-618
-
-
Kontoghiorghe, C.N.1
Kolnagou, A.2
Kontoghiorghes, G.J.3
-
99
-
-
0037431883
-
Deferiprone versus desferrioxamine in thalassaemia, and T2&z.Ast; validation and utility
-
Kontoghiorghes, G.J., and A. Kolnagou: Deferiprone versus desferrioxamine in thalassaemia, and T2&z.ast; validation and utility. Lancet 361,184 (2003)
-
(2003)
Lancet
, vol.361
, pp. 184
-
-
Kontoghiorghes, G.J.1
Kolnagou, A.2
-
100
-
-
0026087617
-
Impaired erythropoietin responsiveness to the anemia in rheumatoid arthritis. A possible inverse relationship with iron stores and effects of the oral iron chelator 1,2-dimethyl-3-hydroxypyrid-4-one
-
Vreugdenhil, G., G.J. Kontoghiorghes, H.G.Van Eijk, and A.J.G. Swaak: Impaired erythropoietin responsiveness to the anemia in rheumatoid arthritis. A possible inverse relationship with iron stores and effects of the oral iron chelator 1,2-dimethyl-3-hydroxypyrid-4-one. Clin Exp Rheumatol 9, 35-40 (1991)
-
(1991)
Clin Exp Rheumatol
, vol.9
, pp. 35-40
-
-
Vreugdenhil, G.1
Kontoghiorghes, G.J.2
Van Eijk, H.G.3
Swaak, A.J.G.4
-
101
-
-
0024311169
-
Efficacy and safety of the oral chelator L1 in anaemic rheumadoit arthritis patients
-
Vreughtenhil, G., G.J. Kontoghiorghes, H.G.Van Eijk, and A.J.G. Swaak: Efficacy and safety of the oral chelator L1 in anaemic rheumadoit arthritis patients. Lancet II, 1398-1399 (1989)
-
(1989)
Lancet
, vol.2
, pp. 1398-1399
-
-
Vreughtenhil, G.1
Kontoghiorghes, G.J.2
Van Eijk, H.G.3
Swaak, A.J.G.4
-
102
-
-
34347370842
-
Selective iron chelation in Friedreich ataxia: Biologic and clinical implications
-
Boddaert N., K.H. Le Quan Sang, A. Rotig, A. Leroy-Willig, S. Gallet, F. Brunelle, D. Sidi, J.C. Thalabard, A. Munnich, and Z.I. Cabantchik: Selective iron chelation in Friedreich ataxia: biologic and clinical implications. Blood 110, 401-408 (2007)
-
(2007)
Blood
, vol.110
, pp. 401-408
-
-
Boddaert, N.1
Le Quan Sang, K.H.2
Rotig, A.3
Leroy-Willig, A.4
Gallet, S.5
Brunelle, F.6
Sidi, D.7
Thalabard, J.C.8
Munnich, A.9
Cabantchik, Z.I.10
-
103
-
-
39149101255
-
Treatment of patients with glomerulonephritis with an oral iron chelator
-
Rajapurkar, M.M., R. Beliga, and S. Shah: Treatment of patients with glomerulonephritis with an oral iron chelator. J Am Soc Nephrol 18, 57-58A (2007)
-
(2007)
J Am Soc Nephrol
, vol.18
-
-
Rajapurkar, M.M.1
Beliga, R.2
Shah, S.3
-
104
-
-
39149105772
-
Novel treatment for diabetic nephropathy
-
Rajapurkar, M.M., M.G. Alam, A. Bhattacharya, and S. Shah: Novel treatment for diabetic nephropathy. J Am Soc Nephrol 18, 329A (2007)
-
(2007)
J Am Soc Nephrol
, vol.18
-
-
Rajapurkar, M.M.1
Alam, M.G.2
Bhattacharya, A.3
Shah, S.4
-
105
-
-
84871448288
-
Effect of deferiprone, an oral iron chelator, in diabetic and non-diabetic glomerular disease
-
Rajapurkar, M.M., U. Hegde, A. Bhattacharya, M.G. Alam, and S.V. Shah: Effect of deferiprone, an oral iron chelator, in diabetic and non-diabetic glomerular disease. Toxicol Mech Methods 23, 5-10 (2013)
-
(2013)
Toxicol Mech Methods
, vol.23
, pp. 5-10
-
-
Rajapurkar, M.M.1
Hegde, U.2
Bhattacharya, A.3
Alam, M.G.4
Shah, S.V.5
-
107
-
-
39349091615
-
Myocyte damage and loss of myofibers is the potential mechanism of iron overload toxicity in congestive cardiac failure in thalasssaemia. Complete reversal of the cardiomyopathy and normalisation of iron load by deferiprone
-
Kolnagou, A., Y. Michaelids, C. Kontos, K. Kyriacou, and G.J. Kontoghiorghes: Myocyte damage and loss of myofibers is the potential mechanism of iron overload toxicity in congestive cardiac failure in thalasssaemia. Complete reversal of the cardiomyopathy and normalisation of iron load by deferiprone. Hemoglobin 32,17-28 (2008)
-
(2008)
Hemoglobin
, vol.32
, pp. 17-28
-
-
Kolnagou, A.1
Michaelids, Y.2
Kontos, C.3
Kyriacou, K.4
Kontoghiorghes, G.J.5
-
108
-
-
0033677772
-
The importance of non-transferrin bound iron in disorders of iron metabolism
-
Breuer, W., C. Hershko, and Z.I. Cabantchik: The importance of non-transferrin bound iron in disorders of iron metabolism. Transf Sc 23, 185-192 (2000)
-
(2000)
Transf Sc
, vol.23
, pp. 185-192
-
-
Breuer, W.1
Hershko, C.2
Cabantchik, Z.I.3
-
109
-
-
0032847475
-
Erythropoiesis: Comparison of cytotoxic aldehyde generation in beta-thalassemia patients chelated with deferoxamine or deferiprone (L1) versus no chelation
-
Bartfay, W.J., D.C. Lehotay, G.D. Sher, E. Bartfay, B. Tyler, X. Luo, and P.P.Liu: Erythropoiesis: Comparison of cytotoxic aldehyde generation in beta-thalassemia patients chelated with deferoxamine or deferiprone (L1) versus no chelation. Hepatology 4, 67-76 (1999)
-
(1999)
Hepatology
, vol.4
, pp. 67-76
-
-
Bartfay, W.J.1
Lehotay, D.C.2
Sher, G.D.3
Bartfay, E.4
Tyler, B.5
Luo, X.6
Liu, P.P.7
-
110
-
-
12544253460
-
Glucose metabolism disorders improvement in patients with thalassaemia major after 24-36 months of intensive chelation therapy
-
Platis, O., G. Anagnostopoulos, K. Farmaki, M. Posantzis, E. Gotsis, and G. Tolis: Glucose metabolism disorders improvement in patients with thalassaemia major after 24-36 months of intensive chelation therapy. Pediatr Endocrinol Rev 2, 279-281 (2004)
-
(2004)
Pediatr Endocrinol Rev
, vol.2
, pp. 279-281
-
-
Platis, O.1
Anagnostopoulos, G.2
Farmaki, K.3
Posantzis, M.4
Gotsis, E.5
Tolis, G.6
-
111
-
-
0035020940
-
Antioxidant treatment improves in vivo cardiac and skeletal muscle bioenergetics in patients with Friedreich's ataxia
-
Lodi, R., P.E. Hart, B. Rajagopalana, D.J. Taylor, J.D. Grilley, J.L. Bradley, A.M. Blamire, D. Manners, P.Styles, A.H. Schapira, and J. M. Cooper: Antioxidant treatment improves in vivo cardiac and skeletal muscle bioenergetics in patients with Friedreich's ataxia. Ann Neurol 49: 590-596 (2001)
-
(2001)
Ann Neurol
, vol.49
, pp. 590-596
-
-
Lodi, R.1
Hart, P.E.2
Rajagopalana, B.3
Taylor, D.J.4
Grilley, J.D.5
Bradley, J.L.6
Blamire, A.M.7
Manners, D.8
Styles, P.9
Schapira, A.H.10
Cooper, J.M.11
-
112
-
-
0034845760
-
Iron in the Hallervorden-Spatz syndrome
-
Koeppen, A.H., and A.C. Dickson: Iron in the Hallervorden-Spatz syndrome. Pediatric Neurolog. 25, 148-155 (2001)
-
(2001)
Pediatric Neurolog
, vol.25
, pp. 148-155
-
-
Koeppen, A.H.1
Dickson, A.C.2
-
113
-
-
0038486942
-
Clinical trial of deferiprone iron chelation therapy in beta-thalassaemia/haemoglobin E patients in Thailand
-
Pootrakul, P., P.Sirankapracha, J. Sankote, U. Kachintorn, W. Maunqsub, K. Sriphen, K. Thakernpol, K. Atisuk, S. Fuchareon, U. Chantraluksri, O. Shalev, and A. V. Hoffbrand: Clinical trial of deferiprone iron chelation therapy in beta-thalassaemia/haemoglobin E patients in Thailand. Br J Haematol 122, 305-310 (2003)
-
(2003)
Br J Haematol
, vol.122
, pp. 305-310
-
-
Pootrakul, P.1
Sirankapracha, P.2
Sankote, J.3
Kachintorn, U.4
Maunqsub, W.5
Sriphen, K.6
Thakernpol, K.7
Atisuk, K.8
Fuchareon, S.9
Chantraluksri, U.10
Shalev, O.11
Hoffbrand, A.V.12
-
114
-
-
70350643852
-
Treatment with deferiprone for iron overload alleviates bone marrow failure in a Fanconi anemia patient
-
Chang, Y.H., C.F. Shaw, K.H. Wu, K.H. Hsieh, Y.N. Su, and P.J. Lu: Treatment with deferiprone for iron overload alleviates bone marrow failure in a Fanconi anemia patient. Hemoglobin 33, 346-351(2009)
-
(2009)
Hemoglobin
, vol.33
, pp. 346-351
-
-
Chang, Y.H.1
Shaw, C.F.2
Wu, K.H.3
Hsieh, K.H.4
Su, Y.N.5
Lu, P.J.6
-
115
-
-
74049116227
-
Normalisation of total body iron load with very intensive combined chelation reverses cardiac and endocrine complications of thalassaemia major
-
Farmaki, K., I. Tzoumari, C. Pappa, G. Chouliaras, and V. Berdoukas: Normalisation of total body iron load with very intensive combined chelation reverses cardiac and endocrine complications of thalassaemia major. Br J Haematol 148, 466-75 (2010)
-
(2010)
Br J Haematol
, vol.148
, pp. 466-475
-
-
Farmaki, K.1
Tzoumari, I.2
Pappa, C.3
Chouliaras, G.4
Berdoukas, V.5
-
116
-
-
0030005823
-
The pharmacokinetics and blood-brain barrier permeation of the chelators 1,2-dimethyl-,1,2-diethyl-, and 1-[ethan-1-ol]-2-methyl-3-hydroxypyridin-4-one in the rat
-
Fredenburg, A.M., R.K. Sethi, D.D. Allen, and R.A. Yokel: The pharmacokinetics and blood-brain barrier permeation of the chelators 1,2-dimethyl-,1,2-diethyl-, and 1-[ethan-1-ol]-2-methyl-3-hydroxypyridin-4-one in the rat. Toxicology 108, 191-199 (1996)
-
(1996)
Toxicology
, vol.108
, pp. 191-199
-
-
Fredenburg, A.M.1
Sethi, R.K.2
Allen, D.D.3
Yokel, R.A.4
-
117
-
-
33745551087
-
Low serum ferritin levels are misleading for detecting cardiac iron overload and increase the risk of cardiomyopathy in thalassemia patients. The importance of cardiac iron overload monitoring using magnetic resonance imaging T2 and T2&z.Ast
-
Kolnagou, A., C. Economides, E. Eracleous, and G.J. Kontoghiorghes: Low serum ferritin levels are misleading for detecting cardiac iron overload and increase the risk of cardiomyopathy in thalassemia patients. The importance of cardiac iron overload monitoring using magnetic resonance imaging T2 and T2&z.ast;. Hemoglobin. 30, 219-227 (2006)
-
(2006)
Hemoglobin
, vol.30
, pp. 219-227
-
-
Kolnagou, A.1
Economides, C.2
Eracleous, E.3
Kontoghiorghes, G.J.4
-
118
-
-
34247103036
-
A randomized, placebo-controlled, double-blind trial of the effect of combined therapy with deferoxamine and deferiprone on myocardial iron in thalassemia major using cardiovascular magnetic resonance
-
Tanner, M.A., R. Galanello, C. Dessi, G.C. Smith, M.A. Westwood, A. Agus, M. Roughton, R. Assomull, S.V. Nair, J.M. Walker, and D.J. Pennell: A randomized, placebo-controlled, double-blind trial of the effect of combined therapy with deferoxamine and deferiprone on myocardial iron in thalassemia major using cardiovascular magnetic resonance. Circulation 115,1876-1884 (2007)
-
(2007)
Circulation
, vol.115
, pp. 1876-1884
-
-
Tanner, M.A.1
Galanello, R.2
Dessi, C.3
Smith, G.C.4
Westwood, M.A.5
Agus, A.6
Roughton, M.7
Assomull, R.8
Nair, S.V.9
Walker, J.M.10
Pennell, D.J.11
-
119
-
-
84878394880
-
Long-term treatment with deferiprone enhances left ventricular ejection function when compared to deferoxamine in patients with thalassemia major
-
Filosa, A., A. Vitrano, P. Rigano, G. Calvaruso, R. Barone, M. Capra, L. Cuccia, F. Gagliardotto, L. Pitrolo, L. Prossomariti, M. Casale, V. Caruso, C. Gerardi, S. Campisi, P. Cianciulli, M. Rizzo, G. D'Ascola, A.Ciancio, and A. Maggio: Long-term treatment with deferiprone enhances left ventricular ejection function when compared to deferoxamine in patients with thalassemia major. Blood Cells Mol Dis 51:85-88 (2013)
-
(2013)
Blood Cells Mol Dis
, vol.51
, pp. 85-88
-
-
Filosa, A.1
Vitrano, A.2
Rigano, P.3
Calvaruso, G.4
Barone, R.5
Capra, M.6
Cuccia, L.7
Gagliardotto, F.8
Pitrolo, L.9
Prossomariti, L.10
Casale, M.11
Caruso, V.12
Gerardi, C.13
Campisi, S.14
Cianciulli, P.15
Rizzo, M.16
D'Ascola, G.17
Ciancio, A.18
Maggio, A.19
-
120
-
-
52449091285
-
Regression of symptoms after selective iron chelation therapy in a case of neurodegeneration with brain iron accumulation
-
Forni, G.L., M. Balocco, L. Cremonesi, G. Abbruzzese, R.C. Parodi, and R. Marchese: Regression of symptoms after selective iron chelation therapy in a case of neurodegeneration with brain iron accumulation. Mov Disord. 23, 904-907 (2008)
-
(2008)
Mov Disord
, vol.23
, pp. 904-907
-
-
Forni, G.L.1
Balocco, M.2
Cremonesi, L.3
Abbruzzese, G.4
Parodi, R.C.5
Marchese, R.6
-
121
-
-
80355129916
-
A pilot trial of deferiprone for neurodegeneration with brain iron accumulation
-
Abbruzzese, G., G. Cossu, M. Balocco, R. Marchese, D. Murgia, M. Melis, R. Galanello, S. Barella, G. Matta, U. Ruffinengo, U. Bonuccelli, and G.L. Forni: A pilot trial of deferiprone for neurodegeneration with brain iron accumulation. Haematologica 96, 1708-1711 (2011)
-
(2011)
Haematologica
, vol.96
, pp. 1708-1711
-
-
Abbruzzese, G.1
Cossu, G.2
Balocco, M.3
Marchese, R.4
Murgia, D.5
Melis, M.6
Galanello, R.7
Barella, S.8
Matta, G.9
Ruffinengo, U.10
Bonuccelli, U.11
Forni, G.L.12
-
122
-
-
78049273304
-
Reduction of body iron stores to normal range levels in thalassaemia by using a deferiprone/deferoxamine combination and their maintenance thereafter by deferiprone monotherapy
-
Kolnagou, A., M. Kleanthous, and G.J. Kontoghiorghes: Reduction of body iron stores to normal range levels in thalassaemia by using a deferiprone/deferoxamine combination and their maintenance thereafter by deferiprone monotherapy. Eur J Haematol 85, 430-438 (2010)
-
(2010)
Eur J Haematol
, vol.85
, pp. 430-438
-
-
Kolnagou, A.1
Kleanthous, M.2
Kontoghiorghes, G.J.3
-
123
-
-
77953249366
-
Maintenance of normal range body iron store levels for up to 4.5 years in thalassemia major patients using deferiprone monotherapy
-
Kolnagou, A., and G.J. Kontoghiorghes: Maintenance of normal range body iron store levels for up to 4.5 years in thalassemia major patients using deferiprone monotherapy. Hemoglobin 34, 204-209 (2010)
-
(2010)
Hemoglobin
, vol.34
, pp. 204-209
-
-
Kolnagou, A.1
Kontoghiorghes, G.J.2
-
124
-
-
77953759472
-
New golden era of chelation therapy in thalassaemia: The achievement and maintenance of normal range body iron stores
-
Kolnagou, A., and G.J. Kontoghiorghes: New golden era of chelation therapy in thalassaemia: the achievement and maintenance of normal range body iron stores. Br J Haematol 150, 489-490 (2010)
-
(2010)
Br J Haematol
, vol.150
, pp. 489-490
-
-
Kolnagou, A.1
Kontoghiorghes, G.J.2
-
125
-
-
77649159219
-
Safety issues of iron chelation therapy in patients with normal range iron stores including thalassaemia, neurodegenerative, renal and infectious diseases
-
Kontoghiorghes, G.J., A. Kolnagou, C.T. Peng, S.V. Shah, and A. Aessopos: Safety issues of iron chelation therapy in patients with normal range iron stores including thalassaemia, neurodegenerative, renal and infectious diseases. Expert Opin Drug Saf. 9, 201-206 (2010)
-
(2010)
Expert Opin Drug Saf
, vol.9
, pp. 201-206
-
-
Kontoghiorghes, G.J.1
Kolnagou, A.2
Peng, C.T.3
Shah, S.V.4
Aessopos, A.5
-
126
-
-
84904349552
-
-
NCT00943748 Health Authority: France: Afssaps-French Health Products Safety Agency. Availble from Study ID Number: 2008-006842-25
-
ClinicalTrials.gov: NCT00943748 Health Authority: France: Afssaps-French Health Products Safety Agency. Availble from http:// clinicaltrials.gov/show/ NCT00943748; Study ID Number: 2008-006842-25
-
-
-
-
127
-
-
77953279926
-
Iron chelation for amelioration of liver ischemia-reperfusion injury
-
Arkadopoulos, N., C. Nastos, K. Kalimeris, E. Economou, K. Theodoraki, E. Kouskouni, A. Pafiti, G. Kostopanagiotou, and V. Smyrniotis: Iron chelation for amelioration of liver ischemia-reperfusion injury. Hemoglobin 34, 265-277 (2010)
-
(2010)
Hemoglobin
, vol.34
, pp. 265-277
-
-
Arkadopoulos, N.1
Nastos, C.2
Kalimeris, K.3
Economou, E.4
Theodoraki, K.5
Kouskouni, E.6
Pafiti, A.7
Kostopanagiotou, G.8
Smyrniotis, V.9
-
128
-
-
56749112247
-
Acquired iron overload associated with antitransferrin monoclonal immunoglobulin: A case report
-
Forni, G.L., D. Girelli, M. Lamagna, M. Mori, E. Marinaro, N. Campostrini, P. Carrara, and M. Maffei: Acquired iron overload associated with antitransferrin monoclonal immunoglobulin: a case report. Am J Hematol. 83, 932-934 (2008)
-
(2008)
Am J Hematol
, vol.83
, pp. 932-934
-
-
Forni, G.L.1
Girelli, D.2
Lamagna, M.3
Mori, M.4
Marinaro, E.5
Campostrini, N.6
Carrara, P.7
Maffei, M.8
-
129
-
-
84876436813
-
The origin of lipofuscin in brown adipocytes of hyperinsulinaemic rats: The role of lipid peroxidation and iron
-
Markelic, M., K. Velickovic, I. Golic, W. Klepal, V. Otasevic, A. Stancic, A. Jankovic, M. Vucetic, B. Buzadzic, B. Korac and A. Korac: The origin of lipofuscin in brown adipocytes of hyperinsulinaemic rats: the role of lipid peroxidation and iron. Histol Histopathol 28, 493-503 (2013)
-
(2013)
Histol Histopathol
, vol.28
, pp. 493-503
-
-
Markelic, M.1
Velickovic, K.2
Golic, I.3
Klepal, W.4
Otasevic, V.5
Stancic, A.6
Jankovic, A.7
Vucetic, M.8
Buzadzic, B.9
Korac, B.10
Korac, A.11
-
130
-
-
79952694447
-
Combined therapy with idebenone and deferiprone in patients with Friedreich's ataxia
-
Velasco-Sánchez, D., A. Aracil, R. Montero, A. Mas, L. Jiménez, M. O'Callaghan, M. Tondo, A. Capdevila, J. Blanch, R. Artuch, and M. Pineda: Combined therapy with idebenone and deferiprone in patients with Friedreich's ataxia. Cerebellum 10, 1-8 (2011)
-
(2011)
Cerebellum
, vol.10
, pp. 1-8
-
-
Velasco-Sánchez, D.1
Aracil, A.2
Montero, R.3
Mas, A.4
Jiménez, L.5
O'Callaghan, M.6
Tondo, M.7
Capdevila, A.8
Blanch, J.9
Artuch, R.10
Pineda, M.11
-
131
-
-
84873731090
-
Gender-related reference intervals of urinary 8-oxo-7,8-dihydro-2′- deoxyguanosine determined by liquid chromatography-tandem mass spectrometry in Serbian population
-
Topic, A., D. Francuski, B. Markovic, M. Stankovic, S. Dobrivojevic, S. Drca, and D. Radojkovic: Gender-related reference intervals of urinary 8-oxo-7,8-dihydro-2′- deoxyguanosine determined by liquid chromatography-tandem mass spectrometry in Serbian population. Clin Biochem. 46,321-326 (2013)
-
(2013)
Clin Biochem
, vol.46
, pp. 321-326
-
-
Topic, A.1
Francuski, D.2
Markovic, B.3
Stankovic, M.4
Dobrivojevic, S.5
Drca, S.6
Radojkovic, D.7
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