-
1
-
-
0032878232
-
Iron-regulatory proteins, iron-responsive elements and ferritin mRNA translation
-
Thomson AM, Rogers JT, Leedman PJ. Iron-regulatory proteins, iron-responsive elements and ferritin mRNA translation. Int J Biochem Cell Biol 1999; 31: 1139-52
-
(1999)
Int J Biochem Cell Biol
, vol.31
, pp. 1139-1152
-
-
Thomson, A.M.1
Rogers, J.T.2
Leedman, P.J.3
-
2
-
-
0031567095
-
The molecular mechanisms of the metabolism and transport of iron in normal and neoplastic cells
-
Richardson DR, Ponka P. The molecular mechanisms of the metabolism and transport of iron in normal and neoplastic cells. Biochim Biophys Acta 1997; 1331: 1-40
-
(1997)
Biochim Biophys Acta
, vol.1331
, pp. 1-40
-
-
Richardson, D.R.1
Ponka, P.2
-
3
-
-
0020648765
-
Community control of hereditary anaemias
-
World Health Organisation. Community control of hereditary anaemias WHO Bull 1983; 61: 63-80
-
(1983)
WHO Bull
, vol.61
, pp. 63-80
-
-
-
7
-
-
84878679996
-
Chemical analysis
-
Elving PJ, Kolthoff IM, editors. New York: Interscience Pub
-
Ringborn A. Chemical analysis. In: Elving PJ, Kolthoff IM, editors. Complexation in analytical chemistry. New York: Interscience Pub, 1963: 1-374
-
(1963)
Complexation in Analytical Chemistry
, pp. 1-374
-
-
Ringborn, A.1
-
10
-
-
0001792753
-
Oral chelation in the treatment of thalassaemia and other diseases
-
Kontoghiorghes GJ, editor. Oral chelation in the treatment of thalassaemia and other diseases. Drugs Today (Barc) 1992; 28 Suppl. A: 1-187
-
(1992)
Drugs Today (Barc)
, vol.28
, Issue.SUPPL. A
, pp. 1-187
-
-
Kontoghiorghes, G.J.1
-
11
-
-
0025569762
-
Design, properties and effective use of the oral chelator L1 and other α-ketohydroxypyridines in the treatment of transfusional iron overload in thalassaemia
-
Kontoghiorghes GJ. Design, properties and effective use of the oral chelator L1 and other α-ketohydroxypyridines in the treatment of transfusional iron overload in thalassaemia. Ann N Y Acad Sci 1990; 612: 339-50
-
(1990)
Ann N Y Acad Sci
, vol.612
, pp. 339-350
-
-
Kontoghiorghes, G.J.1
-
12
-
-
0028840530
-
Comparative efficacy and toxicity of desferrioxamine, deferiprone and other iron and aluminium chelating drugs
-
Kontoghiorghes GJ. Comparative efficacy and toxicity of desferrioxamine, deferiprone and other iron and aluminium chelating drugs. Toxicol Lett 1995; 80: 1-18
-
(1995)
Toxicol Lett
, vol.80
, pp. 1-18
-
-
Kontoghiorghes, G.J.1
-
13
-
-
0032887235
-
Deferiprone: A review of its clinical potential in iron overload in β-thalassaemia major and other transfusion dependent diseases
-
Barman Balfour JA, Foster RH. Deferiprone: a review of its clinical potential in iron overload in β-thalassaemia major and other transfusion dependent diseases. Drugs 1999; 58 (3): 553-78
-
(1999)
Drugs
, vol.58
, Issue.3
, pp. 553-578
-
-
Barman Balfour, J.A.1
Foster, R.H.2
-
14
-
-
0033693878
-
Transfusional iron overload and chelation therapy with deferoxamine and deferiprone (L1)
-
Kontoghiorghes GJ, Pattichi K, Hadjigavriel M, et al. Transfusional iron overload and chelation therapy with deferoxamine and deferiprone (L1). Transfus Sci 2000; 23: 211-23
-
(2000)
Transfus Sci
, vol.23
, pp. 211-223
-
-
Kontoghiorghes, G.J.1
Pattichi, K.2
Hadjigavriel, M.3
-
15
-
-
0035107231
-
Clinical use, therapeutic aspects and future potential of deferiprone in thalassaemia and other conditions of iron and other metal toxicity
-
Kontoghiorghes GJ. Clinical use, therapeutic aspects and future potential of deferiprone in thalassaemia and other conditions of iron and other metal toxicity. Drugs Today (Barc) 2001; 37: 23-35
-
(2001)
Drugs Today (Barc)
, vol.37
, pp. 23-35
-
-
Kontoghiorghes, G.J.1
-
16
-
-
0033034080
-
Meta-analytic review of the clinical effectiveness of oral deferiprone (L1)
-
Addis A, Loebstein R, Koren G, et al. Meta-analytic review of the clinical effectiveness of oral deferiprone (L1). Eur J Clin Pharmacol 1999; 55: 1-6
-
(1999)
Eur J Clin Pharmacol
, vol.55
, pp. 1-6
-
-
Addis, A.1
Loebstein, R.2
Koren, G.3
-
17
-
-
0031457203
-
A risk benefit assessment of iron chelation therapy
-
Porter JB. A risk benefit assessment of iron chelation therapy. Drug Saf 1997; 17 (6): 407-21
-
(1997)
Drug Saf
, vol.17
, Issue.6
, pp. 407-421
-
-
Porter, J.B.1
-
19
-
-
0027453417
-
Present status and future prospects of oral iron chelation therapy in thalassaemia and other diseases
-
Kontoghiorghes GJ. Present status and future prospects of oral iron chelation therapy in thalassaemia and other diseases. Indian J Paediatr 1993; 60: 485-507
-
(1993)
Indian J Paediatr
, vol.60
, pp. 485-507
-
-
Kontoghiorghes, G.J.1
-
20
-
-
0024337363
-
Survival and causes of death in thalassaemia major
-
Zurlo MG, De Stefano P, Borgna-Pignatti C, et al. Survival and causes of death in thalassaemia major. Lancet 1989; II: 27-9
-
(1989)
Lancet
, vol.2
, pp. 27-29
-
-
Zurlo, M.G.1
De Stefano, P.2
Borgna-Pignatti, C.3
-
21
-
-
0034631379
-
Survival in beta thalassaemia major in the UK: Data from the UK thalassaemia register
-
Modell B, Khan M, Darlison M. Survival in beta thalassaemia major in the UK: data from the UK thalassaemia register. Lancet 2000; 355: 2051-2
-
(2000)
Lancet
, vol.355
, pp. 2051-2052
-
-
Modell, B.1
Khan, M.2
Darlison, M.3
-
23
-
-
0028897880
-
New concepts of iron and aluminium chelation therapy with oral L1 (deferiprone) and other chelators
-
Kontoghiorghes GJ. New concepts of iron and aluminium chelation therapy with oral L1 (deferiprone) and other chelators. Analyst 1995; 120: 845-51
-
(1995)
Analyst
, vol.120
, pp. 845-851
-
-
Kontoghiorghes, G.J.1
-
24
-
-
0026683009
-
Deferoxamine, cyclophosphamide, etoposide, carboplatin and thotepa (D-CE-CAT): A new cytoreductive chelation-chemotherapy regimen in patients with advanced neuroblastoma
-
Donfrancesco A, Deb G, Domicini C, et al. Deferoxamine, cyclophosphamide, etoposide, carboplatin and thotepa (D-CE-CAT): a new cytoreductive chelation-chemotherapy regimen in patients with advanced neuroblastoma. Am J Clin Oncol 1992; 15: 319-22
-
(1992)
Am J Clin Oncol
, vol.15
, pp. 319-322
-
-
Donfrancesco, A.1
Deb, G.2
Domicini, C.3
-
25
-
-
0033678071
-
Combining iron chelators with the nucleoside analog didanosine in anti-HIV therapy
-
Georgiou NA, Van der Bruggen J, Oudshoorn M, et al. Combining iron chelators with the nucleoside analog didanosine in anti-HIV therapy. Transfus Sci 2000; 23: 249-50
-
(2000)
Transfus Sci
, vol.23
, pp. 249-250
-
-
Georgiou, N.A.1
Van Der Bruggen, J.2
Oudshoorn, M.3
-
26
-
-
0024348430
-
Comparison of antineuroblastoma activity of desferrioxamine with that of oral iron chelators
-
Blatt J, Taylor S, Kontoghiorghes GJ. Comparison of antineuroblastoma activity of desferrioxamine with that of oral iron chelators. Cancer Res 1989; 49: 2925-7
-
(1989)
Cancer Res
, vol.49
, pp. 2925-2927
-
-
Blatt, J.1
Taylor, S.2
Kontoghiorghes, G.J.3
-
27
-
-
0022871715
-
Cytotoxic and DNA inhibitory effects of iron chelators on human leukaemic cell lines
-
Kontoghiorghes GJ, Piga A, Hoffbrand AV. Cytotoxic and DNA inhibitory effects of iron chelators on human leukaemic cell lines. Haematol Oncol 1986; 4: 195-204
-
(1986)
Haematol Oncol
, vol.4
, pp. 195-204
-
-
Kontoghiorghes, G.J.1
Piga, A.2
Hoffbrand, A.V.3
-
28
-
-
0036222988
-
Antiproliferative and apoptotic effects of iron chelators on human cervical carcinoma cells
-
Simonart T, Boelaert JR, Mosselmans R, et al. Antiproliferative and apoptotic effects of iron chelators on human cervical carcinoma cells. Gynecol Oncol 2002; 85: 95-102
-
(2002)
Gynecol Oncol
, vol.85
, pp. 95-102
-
-
Simonart, T.1
Boelaert, J.R.2
Mosselmans, R.3
-
29
-
-
0037579322
-
-
Protein hydroxylation inhibitors for fibroproliferative disorders. World Patent WO 9622021
-
Hanauske-Abel HM, McCaffrey TA, Grady R. Protein hydroxylation inhibitors for fibroproliferative disorders. World Patent WO 9622021
-
-
-
Hanauske-Abel, H.M.1
McCaffrey, T.A.2
Grady, R.3
-
30
-
-
0026511418
-
Iron depletion: A defence against intracellular infection and neoplasm
-
Weinberg ED. Iron depletion: a defence against intracellular infection and neoplasm. Life Sci 1992; 50: 1289-97
-
(1992)
Life Sci
, vol.50
, pp. 1289-1297
-
-
Weinberg, E.D.1
-
31
-
-
0028963594
-
Iron: Mammalian defence systems, mechanisms of disease and chelation therapy approaches
-
Kontoghiorghes GJ, Weinberg ED. Iron: mammalian defence systems, mechanisms of disease and chelation therapy approaches. Blood Rev 1995; 9: 33-46
-
(1995)
Blood Rev
, vol.9
, pp. 33-46
-
-
Kontoghiorghes, G.J.1
Weinberg, E.D.2
-
32
-
-
0036148173
-
Effects on mycobacterium avium replication in normal human macrophages by deferiprone (L1) and other iron chelators. Possible implications on toxicity
-
Douvas SG, May MH, Kolnagou A, et al. Effects on mycobacterium avium replication in normal human macrophages by deferiprone (L1) and other iron chelators. Possible implications on toxicity. Arzneimittel Forschung 2002; 52: 45-52
-
(2002)
Arzneimittel Forschung
, vol.52
, pp. 45-52
-
-
Douvas, S.G.1
May, M.H.2
Kolnagou, A.3
-
33
-
-
0023671209
-
The effect of synthetic iron chelators on bacterial growth in human serum
-
Brock JH, Liceaga J, Kontoghiotghes GJ. The effect of synthetic iron chelators on bacterial growth in human serum. FEMS Microbiol Immunol 1988; 47: 55-60
-
(1988)
FEMS Microbiol Immunol
, vol.47
, pp. 55-60
-
-
Brock, J.H.1
Liceaga, J.2
Kontoghiotghes, G.J.3
-
34
-
-
0036090462
-
Comparison of the effects of deferiprone versus deferoxamine on growth and virulence of Yersinia enterocolitica
-
Lesic B, Foulon J, Carniel E. Comparison of the effects of deferiprone versus deferoxamine on growth and virulence of Yersinia enterocolitica. Antimicrob Agents Chemother 2002; 46: 1741-5
-
(2002)
Antimicrob Agents Chemother
, vol.46
, pp. 1741-1745
-
-
Lesic, B.1
Foulon, J.2
Carniel, E.3
-
35
-
-
0023694668
-
Antimalarial properties of orally active iron chelators
-
Heppner DG, Hallaway PE, Kontoghiorghes GJ, et al. Antimalarial properties of orally active iron chelators. Blood 1988; 72: 358-61
-
(1988)
Blood
, vol.72
, pp. 358-361
-
-
Heppner, D.G.1
Hallaway, P.E.2
Kontoghiorghes, G.J.3
-
36
-
-
0027092741
-
Growth inhibition of Plasmodium Falciparum by orally active iron chelators
-
Mastrandrea S, Carvajal JL, Kaeda JS, et al. Growth inhibition of Plasmodium Falciparum by orally active iron chelators. Drugs Today (Barc) 1992; 28 Suppl. A: 25-7
-
(1992)
Drugs Today (Barc)
, vol.18
, Issue.SUPPL. A
, pp. 25-27
-
-
Mastrandrea, S.1
Carvajal, J.L.2
Kaeda, J.S.3
-
37
-
-
0026530692
-
Iron chelation with desferrioxamine B in adults with asymptomatic P. Falciparum parasitemia
-
Gordeuk VR, Thuma PE, Brittenham GM, et al. Iron chelation with desferrioxamine B in adults with asymptomatic P. Falciparum parasitemia. Blood 1992; 79: 308-12
-
(1992)
Blood
, vol.79
, pp. 308-312
-
-
Gordeuk, V.R.1
Thuma, P.E.2
Brittenham, G.M.3
-
38
-
-
0035986016
-
Deferiprone (L1 ) as an adjuvant therapy for Plasmodium falciparum malaria
-
Mohanty D, Ghosh K, Pathare AV, et al. Deferiprone (L1 ) as an adjuvant therapy for Plasmodium falciparum malaria. Indian J Med Res 2002; 115: 17-21
-
(2002)
Indian J Med Res
, vol.115
, pp. 17-21
-
-
Mohanty, D.1
Ghosh, K.2
Pathare, A.V.3
-
39
-
-
0025669925
-
Chelators affecting iron absorption in mice
-
Kontoghiorghes GJ. Chelators affecting iron absorption in mice. Arzneimittel Forschung 1990; 40: 1332-5
-
(1990)
Arzneimittel Forschung
, vol.40
, pp. 1332-1335
-
-
Kontoghiorghes, G.J.1
-
40
-
-
0026087617
-
Impaired erythropoietin responsiveness to the anemia in rheumatoid arthritis: A possible inverse relationship with iron stores and effects of the oral iron chelator 1,2-dimethyl-3-hydroxypyrid-4-one
-
Vreugdenhil G, Kontoghiorghes GJ, Van Eijk HG, et al. Impaired erythropoietin responsiveness to the anemia in rheumatoid arthritis: a possible inverse relationship with iron stores and effects of the oral iron chelator 1,2-dimethyl-3-hydroxypyrid-4-one. Clin Exp Rheumatol 1991; 9: 35-40
-
(1991)
Clin Exp Rheumatol
, vol.9
, pp. 35-40
-
-
Vreugdenhil, G.1
Kontoghiorghes, G.J.2
Van Eijk, H.G.3
-
41
-
-
0021637231
-
Increased storage of iron and anaemia in rheumatoid arthritis: Usefulness of desferrioxamine
-
Giordano N, Fioravanti A, Sancasciani S, et al. Increased storage of iron and anaemia in rheumatoid arthritis: usefulness of desferrioxamine. BMJ 1984; 289: 961-2
-
(1984)
BMJ
, vol.289
, pp. 961-962
-
-
Giordano, N.1
Fioravanti, A.2
Sancasciani, S.3
-
42
-
-
0024311169
-
Efficacy and safety of the oral chelator L1 in anaemic rheumatoid arthritis patients
-
Vreughtenhil G, Kontoghiorghes GJ, Van Eijk, et al. Efficacy and safety of the oral chelator L1 in anaemic rheumatoid arthritis patients. Lancet 1989; II: 1398-9
-
(1989)
Lancet
, vol.2
, pp. 1398-1399
-
-
Vreughtenhil, G.1
Kontoghiorghes, G.J.2
Van Eijk3
-
43
-
-
0035020940
-
Antioxidant treatment improves in vivo cardiac and skeletal muscle bioenergetics in patients with Friedreich's ataxia
-
Lodi R, Hart PE, Rajagopalana B, et al. Antioxidant treatment improves in vivo cardiac and skeletal muscle bioenergetics in patients with Friedreich's ataxia. Ann Neurol 2001; 49: 590-6
-
(2001)
Ann Neurol
, vol.49
, pp. 590-596
-
-
Lodi, R.1
Hart, P.E.2
Rajagopalana, B.3
-
44
-
-
0034845760
-
Iron in the Hallervorden-Spatz syndrome
-
Koeppen AH, Dickson AC. Iron in the Hallervorden-Spatz syndrome. Pediatr Neurol 2001; 25: 148-55
-
(2001)
Pediatr Neurol
, vol.25
, pp. 148-155
-
-
Koeppen, A.H.1
Dickson, A.C.2
-
45
-
-
0024402583
-
Prevention of postischemic cardiac injury by the orally active iron chelator 1,2-dimethyl-3-hydroxy-4-pyridone (L1) and the antioxidant (+)-cyanidanol-3
-
Van der Kraaij AMM, Van Eijk HG, Koster JF. Prevention of postischemic cardiac injury by the orally active iron chelator 1,2-dimethyl-3-hydroxy-4-pyridone (L1) and the antioxidant (+)-cyanidanol-3. Circulation 1989; 80: 158-64
-
(1989)
Circulation
, vol.80
, pp. 158-164
-
-
Van Der Kraaij, A.M.M.1
Van Eijk, H.G.2
Koster, J.F.3
-
46
-
-
0027093383
-
Free radical status of blood of patients with iron overload: The effect of chelating treatment
-
Korkina LG, Afanas'ev IB, Deeva IB, et al. Free radical status of blood of patients with iron overload: the effect of chelating treatment. Drugs Today (Barc) 1992; 28 Suppl. A: 137-41
-
(1992)
Drugs Today (Barc)
, vol.28
, Issue.SUPPL. A
, pp. 137-141
-
-
Korkina, L.G.1
Afanas'ev, I.B.2
Deeva, I.B.3
-
47
-
-
0037579319
-
Differentiation of the therapeutic and toxicological effects of iron and copper chelating drugs in relation to free radical toxicity
-
Kontoghiorghes GJ, Bunce T, Bruckdorfer KR. Differentiation of the therapeutic and toxicological effects of iron and copper chelating drugs in relation to free radical toxicity. Toxicol Lett 1995; 78: 48-9
-
(1995)
Toxicol Lett
, vol.78
, pp. 48-49
-
-
Kontoghiorghes, G.J.1
Bunce, T.2
Bruckdorfer, K.R.3
-
48
-
-
0033694227
-
L1 effects on reactive oxygen (ROS) and nitrogen species (RNS) release, haemoglobin oxidation, low molecular weight antioxidants, and antioxidant enzyme activities in red and white blood cells of thalassaemic patients
-
Korkina L, De Luca C, Deeva I, et al. L1 effects on reactive oxygen (ROS) and nitrogen species (RNS) release, haemoglobin oxidation, low molecular weight antioxidants, and antioxidant enzyme activities in red and white blood cells of thalassaemic patients. Transfus Sci 2000; 23: 253-4
-
(2000)
Transfus Sci
, vol.23
, pp. 253-254
-
-
Korkina, L.1
De Luca, C.2
Deeva, I.3
-
49
-
-
0035894070
-
Iron complexes of deferiprone and dietary plant catechols as cytoprotective superoxide radical scavengers
-
Moridani MY, O'Brien PJ. Iron complexes of deferiprone and dietary plant catechols as cytoprotective superoxide radical scavengers. Biochem Pharmacol 2001; 62: 1579-85
-
(2001)
Biochem Pharmacol
, vol.62
, pp. 1579-1585
-
-
Moridani, M.Y.1
O'Brien, P.J.2
-
50
-
-
0031277617
-
Iron and atherosclerosis: Inhibition by the iron chelator deferiprone (L1)
-
Matthews AJ, Vercellotti GM, Menchaca HJ, et al. Iron and atherosclerosis: inhibition by the iron chelator deferiprone (L1). J Surg Res 1997; 73: 35-40
-
(1997)
J Surg Res
, vol.73
, pp. 35-40
-
-
Matthews, A.J.1
Vercellotti, G.M.2
Menchaca, H.J.3
-
51
-
-
0030780828
-
Systemic administration of the iron chelator deferiprone attenuates subarachnoid hemorrhage-induced cerebral vasospasm in the rabbit
-
Arthur AS, Fergus AH, Lanzino G, et al. Systemic administration of the iron chelator deferiprone attenuates subarachnoid hemorrhage-induced cerebral vasospasm in the rabbit. Neurosurgery 1997; 41: 1385-91
-
(1997)
Neurosurgery
, vol.41
, pp. 1385-1391
-
-
Arthur, A.S.1
Fergus, A.H.2
Lanzino, G.3
-
52
-
-
0037051144
-
The influence of deferiprone (L1) and deferoxamine on iron and essential element tissue level and parameters of oxidative status in dietary iron-loaded mice
-
Eybl V, Kotyzova D, Kolek M, et al. The influence of deferiprone (L1) and deferoxamine on iron and essential element tissue level and parameters of oxidative status in dietary iron-loaded mice. Toxicol Lett 2002; 128: 169-75
-
(2002)
Toxicol Lett
, vol.128
, pp. 169-175
-
-
Eybl, V.1
Kotyzova, D.2
Kolek, M.3
-
53
-
-
0023821040
-
The iron chelators desferrioxamine and 1-alkyl-methyl-3-hydroxypyrid-4-ones inhibit vascular prostacyclin synthesis in vitro
-
Jeremy JY, Kontoghiorghes GJ, Hoffbrand AV, et al. The iron chelators desferrioxamine and 1-alkyl-methyl-3-hydroxypyrid-4-ones inhibit vascular prostacyclin synthesis in vitro. Biochem J 1988; 254: 239-44
-
(1988)
Biochem J
, vol.254
, pp. 239-244
-
-
Jeremy, J.Y.1
Kontoghiorghes, G.J.2
Hoffbrand, A.V.3
-
54
-
-
0024503575
-
Iron chelators inhibit human platelet aggregation, thromboxane A synthesis and lipoxygenase activity
-
Barradas MA, Jeremy J, Kontoghiorghes GJ, et al. Iron chelators inhibit human platelet aggregation, thromboxane A synthesis and lipoxygenase activity. FEBS Lett 1989; 245: 105-9
-
(1989)
FEBS Lett
, vol.245
, pp. 105-109
-
-
Barradas, M.A.1
Jeremy, J.2
Kontoghiorghes, G.J.3
-
55
-
-
0025942977
-
Cardioxane-ICRF 187: Towards anticancer drug specificity through selective toxicity reduction
-
Koning J, Palmer P, Franks GR, et al. Cardioxane-ICRF 187: towards anticancer drug specificity through selective toxicity reduction. Cancer Treat Rev 1991; 18: 1-19
-
(1991)
Cancer Treat Rev
, vol.18
, pp. 1-19
-
-
Koning, J.1
Palmer, P.2
Franks, G.R.3
-
56
-
-
0023693833
-
Protective effect of the bispiperazinedione ICRF-187 against doxorubicin-induced cardiac toxicity in women with advanced breast cancer
-
Speyer JL, Green MD, Kramer E, et al. Protective effect of the bispiperazinedione ICRF-187 against doxorubicin-induced cardiac toxicity in women with advanced breast cancer. N Engl J Med 1988; 319: 745-52
-
(1988)
N Engl J Med
, vol.319
, pp. 745-752
-
-
Speyer, J.L.1
Green, M.D.2
Kramer, E.3
-
57
-
-
0037098878
-
Deferiprone protects against doxorubicin-induced myocyte cytotoxicity
-
Barnabe N, Zastre JA, Venkataram S, et al. Deferiprone protects against doxorubicin-induced myocyte cytotoxicity. Free Radic Biol Med 2002; 33: 266-75
-
(2002)
Free Radic Biol Med
, vol.33
, pp. 266-275
-
-
Barnabe, N.1
Zastre, J.A.2
Venkataram, S.3
-
58
-
-
0026636441
-
Cross CE Free radicals, antioxidants and human disease: Where are we now?
-
Halliwell B, Gutteridge JMC, Cross CE Free radicals, antioxidants and human disease: where are we now? J Lab Clin Med 1992; 119: 598-620
-
(1992)
J Lab Clin Med
, vol.119
, pp. 598-620
-
-
Halliwell, B.1
Gutteridge, J.M.C.2
-
59
-
-
0026306055
-
Influence of iron chelators: 1,2-dialkyl-3-hydroxypyridin-4-ones on the lipid peroxidation and glutathione levels in the liver in mice
-
Eybl V, Caisova D, Koutensky J, et al. Influence of iron chelators: 1,2-dialkyl-3-hydroxypyridin-4-ones on the lipid peroxidation and glutathione levels in the liver in mice. Arch Toxicol Suppl 1991; 14: 185-7
-
(1991)
Arch Toxicol Suppl
, vol.14
, pp. 185-187
-
-
Eybl, V.1
Caisova, D.2
Koutensky, J.3
-
60
-
-
0025726462
-
Intramuscular desferioxamine in patients with Alzheimer's disease
-
McLachlan CDR, Dalton AJ, Kruch TPA, et al. Intramuscular desferioxamine in patients with Alzheimer's disease. Lancet 1991; I: 1304-8
-
(1991)
Lancet
, vol.2
, pp. 1304-1308
-
-
McLachlan, C.D.R.1
Dalton, A.J.2
Kruch, T.P.A.3
-
61
-
-
0003431317
-
Mobilisation of plutonium and iron from transferrin and ferritin by hydroxypyridone chelators
-
Taylor DM, Kontoghiorghes GJ. Mobilisation of plutonium and iron from transferrin and ferritin by hydroxypyridone chelators. Inorg Chim Acta 1986; 125: L35-8
-
(1986)
Inorg Chim Acta
, vol.125
-
-
Taylor, D.M.1
Kontoghiorghes, G.J.2
-
62
-
-
0027102249
-
Interaction of L1, L1NA11 and deferoxamine with gallium in vivo
-
Eybl V, Svihovcova P, Koutensky J, et al. Interaction of L1, L1NA11 and deferoxamine with gallium in vivo. Drugs Today (Barc) 1992; 29 Suppl. A: 173-5
-
(1992)
Drugs Today (Barc)
, vol.29
, Issue.SUPPL. A
, pp. 173-175
-
-
Eybl, V.1
Svihovcova, P.2
Koutensky, J.3
-
63
-
-
0037917350
-
-
Technetium-99m complexes with N-substituted 3-hydroxy-4-pridinones. World Patent WO 9310822
-
Edwards DS, Christopher ER, Poirier MJ. Technetium-99m complexes with N-substituted 3-hydroxy-4-pridinones. World Patent WO 9310822
-
-
-
Edwards, D.S.1
Christopher, E.R.2
Poirier, M.J.3
-
64
-
-
0003008754
-
Safety and risk of Gadolinium-DTPA: Extended clinical experience after more than 5,000,000 applications
-
Felix R, Heshiki A, Hosten N, et al., editors. Oxford: Blackwell Science Pub
-
Niendorf HP, Alhassan A, Balzer TH, et al. Safety and risk of Gadolinium-DTPA: extended clinical experience after more than 5,000,000 applications. In: Felix R, Heshiki A, Hosten N, et al., editors. Gadopentetate dimeglumine (Gd-DTPA) Magnevist monograph. Oxford: Blackwell Science Pub, 1994: 21-31
-
(1994)
Gadopentetate Dimeglumine (Gd-DTPA) Magnevist Monograph
, pp. 21-31
-
-
Niendorf, H.P.1
Alhassan, A.2
Balzer, T.H.3
-
65
-
-
0027054370
-
Aluminium removal: Short and long term preliminary results with L1 in rats
-
Elorriaga R, Fernandez Martin JL, Menendez Fraga P, et al. Aluminium removal: short and long term preliminary results with L1 in rats. Drugs Today (Barc) 1992; 28 Suppl. A: 177-82
-
(1992)
Drugs Today (Barc)
, vol.28
, Issue.SUPPL. A
, pp. 177-182
-
-
Elorriaga, R.1
Fernandez Martin, J.L.2
Menendez Fraga, P.3
-
66
-
-
0028196693
-
Studies of aluminium mobilisation in renal dialysis patients using the oral chelator 1,2-dimethyl-3-hydroxypyrid-4-one
-
Kontoghiorghes GJ, Barr J, Baillod RA. Studies of aluminium mobilisation in renal dialysis patients using the oral chelator 1,2-dimethyl-3-hydroxypyrid-4-one. Arzneimittel Forschung 1994; 44: 522-6
-
(1994)
Arzneimittel Forschung
, vol.44
, pp. 522-526
-
-
Kontoghiorghes, G.J.1
Barr, J.2
Baillod, R.A.3
-
67
-
-
0035664696
-
Molecular factors affecting the complex formation between deferiprone (L1) ans Cu(II): Possible implications on efficacy and toxicity
-
Pashalidis I, Kontoghiorghes GJ. Molecular factors affecting the complex formation between deferiprone (L1) ans Cu(II): possible implications on efficacy and toxicity. Arzneimittel Forschung 2001; 51: 998-1003
-
(2001)
Arzneimittel Forschung
, vol.51
, pp. 998-1003
-
-
Pashalidis, I.1
Kontoghiorghes, G.J.2
-
68
-
-
0027081269
-
Retention of injected plutonium and americium in mice and rats after oral treatment with DTPA, desferrioxamine and alpha-ketohydroxypyridines
-
Volf V, Kontoghiorghes GJ. Retention of injected plutonium and americium in mice and rats after oral treatment with DTPA, desferrioxamine and alpha-ketohydroxypyridines. Drugs Today (Barc) 1992; 28 Suppl. A: 169-72
-
(1992)
Drugs Today (Barc)
, vol.28
, Issue.SUPPL. A
, pp. 169-172
-
-
Volf, V.1
Kontoghiorghes, G.J.2
-
69
-
-
0032729867
-
Effective complex formation in the interaction of I,2-dimethyl-3-hydroxypyrid-4-one (deferiprone or L1) with uranium (VI)
-
Pashalidis I, Kontoghiorghes GJ. Effective complex formation in the interaction of I,2-dimethyl-3-hydroxypyrid-4-one (deferiprone or L1) with uranium (VI). J Radioanalyt Nucl Chem 1999; 242: 181-4
-
(1999)
J Radioanalyt Nucl Chem
, vol.242
, pp. 181-184
-
-
Pashalidis, I.1
Kontoghiorghes, G.J.2
-
70
-
-
0027066785
-
Comparison of the drugs used for the treatment of iron overload with drugs that have the potential for the same purpose
-
Martell AE, Motekaitis RJ, Clarke ET, et al. Comparison of the drugs used for the treatment of iron overload with drugs that have the potential for the same purpose. Drugs Today (Barc) 1992; 28 Suppl. A: 11-8
-
(1992)
Drugs Today (Barc)
, vol.28
, Issue.SUPPL. A
, pp. 11-18
-
-
Martell, A.E.1
Motekaitis, R.J.2
Clarke, E.T.3
-
72
-
-
0021939956
-
Evidence of aluminium loading in infants receiving intravenous therapy
-
Sedman AB, Klein LG, Merrit RJ, et al. Evidence of aluminium loading in infants receiving intravenous therapy. N Engl J Med 1985; 312: 1337-43
-
(1985)
N Engl J Med
, vol.312
, pp. 1337-1343
-
-
Sedman, A.B.1
Klein, L.G.2
Merrit, R.J.3
-
73
-
-
0000981188
-
Alzheimer's disease and the aluminium hypothesis
-
Nicolini M, Zatta PF, Corain B, editors. New York: Raven Press
-
Edwardson JA. Ferrier IN, McArthur FK, et al. Alzheimer's disease and the aluminium hypothesis. In: Nicolini M, Zatta PF, Corain B, editors. Aluminium in chemistry, biology and medicine. New York: Raven Press, 1992: 85-96
-
(1992)
Aluminium in Chemistry, Biology and Medicine
, pp. 85-96
-
-
Edwardson, J.A.1
Ferrier, I.N.2
McArthur, F.K.3
-
74
-
-
0022672319
-
Toxicity from aluminium and iron: Recognition, treatment and prevention
-
Kurtzman NA, editor. Toxicity from aluminium and iron: recognition, treatment and prevention. Semin Nephrol 1986; 6 Suppl. 1: 1-41
-
(1986)
Semin Nephrol
, vol.6
, Issue.SUPPL. 1
, pp. 1-41
-
-
Kurtzman, N.A.1
-
75
-
-
0024834620
-
Effects of deferoxamine, feroxamine and iron on experimental mucormycosis (zygomycosis)
-
Van Cutsem J, Boelaert JR. Effects of deferoxamine, feroxamine and iron on experimental mucormycosis (zygomycosis). Kidney Int 1989; 36: 1061-8
-
(1989)
Kidney Int
, vol.36
, pp. 1061-1068
-
-
Van Cutsem, J.1
Boelaert, J.R.2
-
76
-
-
0026089779
-
Fatal systemic lupus erythematosus in patient taking oral iron chelator L1
-
Mehta J, Singhal S, Revanker R, et al. Fatal systemic lupus erythematosus in patient taking oral iron chelator L1 [letter]. Lancet 1991; I: 298
-
(1991)
Lancet
, vol.1
, pp. 298
-
-
Mehta, J.1
Singhal, S.2
Revanker, R.3
-
77
-
-
0026426345
-
Antinuclear antibodies in patients taking L1
-
Berdoukas V. Antinuclear antibodies in patients taking L1 [letter]. Lancet 1991; I: 672
-
(1991)
Lancet
, vol.1
, pp. 672
-
-
Berdoukas, V.1
-
78
-
-
0025852382
-
Rarity of systemic lupus erythematosus after oral iron chelator L1
-
Olivieri NF, Koren G, Freedman M, et al. Rarity of systemic lupus erythematosus after oral iron chelator L1. Lancet 1991; I: 924
-
(1991)
Lancet
, vol.1
, pp. 924
-
-
Olivieri, N.F.1
Koren, G.2
Freedman, M.3
-
79
-
-
0027394422
-
Toxicity of oral iron chelator L1
-
Berdoukas V, Bentley P, Frost H, et al. Toxicity of oral iron chelator L1 [letter]. Lancet 1993; 341: 1088
-
(1993)
Lancet
, vol.341
, pp. 1088
-
-
Berdoukas, V.1
Bentley, P.2
Frost, H.3
-
80
-
-
0027500714
-
Development of oral iron chelator L1
-
Hershko C. Development of oral iron chelator L1. Lancet 1993; 343: 1088-9
-
(1993)
Lancet
, vol.343
, pp. 1088-1089
-
-
Hershko, C.1
-
82
-
-
0027216569
-
Misinformation about deferiprone (L1)
-
Kontoghiorghes GJ. Misinformation about deferiprone (L1) [letter]. Lancet 1993; II: 250
-
(1993)
Lancet
, vol.2
, pp. 250
-
-
Kontoghiorghes, G.J.1
-
84
-
-
0032514558
-
Long term safety and effectiveness of iron chelation therapy with deferiprone for thalassaemia major
-
Olivieri NF, Brittenham GM, Mclaren C, et al. Long term safety and effectiveness of iron chelation therapy with deferiprone for thalassaemia major. N Engl J Med 1998; 339: 417-23
-
(1998)
N Engl J Med
, vol.339
, pp. 417-423
-
-
Olivieri, N.F.1
Brittenham, G.M.2
Mclaren, C.3
-
85
-
-
0032514421
-
Iron chelation therapy with oral deferiprone: Toxicity or lack of efficacy
-
Kowdly KV, Kaplan MM. Iron chelation therapy with oral deferiprone: toxicity or lack of efficacy. N Engl J Med 1998; 339: 468-9
-
(1998)
N Engl J Med
, vol.339
, pp. 468-469
-
-
Kowdly, K.V.1
Kaplan, M.M.2
-
86
-
-
0034699758
-
Deferiprone for thalassaemia
-
Pippard MJ, Weatherall DJ. Deferiprone for thalassaemia. Lancet 2001; 356: 1444-5
-
(2001)
Lancet
, vol.356
, pp. 1444-1445
-
-
Pippard, M.J.1
Weatherall, D.J.2
-
87
-
-
0027484892
-
Oral iron chelation: A review with special emphasis on Indian work on deferiprone (L1)
-
Agarwal MB. Oral iron chelation: a review with special emphasis on Indian work on deferiprone (L1). Indian J. Pediatr 1993; 60: 509-16
-
(1993)
Indian J Pediatr
, vol.60
, pp. 509-516
-
-
Agarwal, M.B.1
-
88
-
-
0031849187
-
A multi-centre safety trial of the oral iron chelator deferiprone
-
Cohen A, Galanello R, Piga A, et al. A multi-centre safety trial of the oral iron chelator deferiprone. Ann N Y Acad Sci 1998; 850: 466-8
-
(1998)
Ann N Y Acad Sci
, vol.850
, pp. 466-468
-
-
Cohen, A.1
Galanello, R.2
Piga, A.3
-
89
-
-
0034094839
-
Safety profile of the oral iron chelator deferiprone: A multicentre study
-
Cohen AR, Galanello R, Piga A, et al. Safety profile of the oral iron chelator deferiprone: a multicentre study. Br J Haematol 2000; 108: 305-12
-
(2000)
Br J Haematol
, vol.108
, pp. 305-312
-
-
Cohen, A.R.1
Galanello, R.2
Piga, A.3
-
92
-
-
0038593473
-
-
Method of synthesis of 1,2-dimethyl-3-hydroxypyrid-4-one. Greek patent 1003358. 2000
-
Kontoghiorghes GJ. Method of synthesis of 1,2-dimethyl-3-hydroxypyrid-4-one. Greek patent 1003358. 2000
-
-
-
Kontoghiorghes, G.J.1
-
93
-
-
0018139256
-
Effects of chelating agents and metal ions on the degradation of DNA by bleomycin
-
Sansville EA, Pelsach J, Horwitz SB. Effects of chelating agents and metal ions on the degradation of DNA by bleomycin. Biochemistry 1976; 17: 2740-6
-
(1976)
Biochemistry
, vol.17
, pp. 2740-2746
-
-
Sansville, E.A.1
Pelsach, J.2
Horwitz, S.B.3
-
95
-
-
0023489829
-
Effective chelation of iron in β-thalassaemia with the oral chelator 1, 2-dimethyl-3-hydroxypyrid-4-one
-
Kontoghiorghes GJ, Aldouri MA, Hoffbrand AV, et al. Effective chelation of iron in β-thalassaemia with the oral chelator 1, 2-dimethyl-3-hydroxypyrid-4-one. BMJ 1987; 295: 1509-12
-
(1987)
BMJ
, vol.295
, pp. 1509-1512
-
-
Kontoghiorghes, G.J.1
Aldouri, M.A.2
Hoffbrand, A.V.3
-
96
-
-
0022637547
-
Iron chelation using subcutaneous infusion of diethylene triamine penta-acetic acid (DTPA)
-
Pippard MJ, Jackson MJ, Hoffman K, et al. Iron chelation using subcutaneous infusion of diethylene triamine penta-acetic acid (DTPA). Scand J Haematol 1986; 36: 466-72
-
(1986)
Scand J Haematol
, vol.36
, pp. 466-472
-
-
Pippard, M.J.1
Jackson, M.J.2
Hoffman, K.3
-
97
-
-
0019944568
-
Ferrioxamine excretion in iron loaded man
-
Pippard MJ, Callender ST, Finch CA. Ferrioxamine excretion in iron loaded man. Blood 1982; 60: 288-94
-
(1982)
Blood
, vol.60
, pp. 288-294
-
-
Pippard, M.J.1
Callender, S.T.2
Finch, C.A.3
-
98
-
-
0025018222
-
Long term trial with the oral chelator 1,2-dimethyl-3-hydroxypyrid-4-one (L1). (I) Iron chelation and metabolic studies
-
Kontoghiorghes GJ, Bartlett AN, Hoffbrand AV, et al. Long term trial with the oral chelator 1,2-dimethyl-3-hydroxypyrid-4-one (L1). (I) Iron chelation and metabolic studies. Br J Haematol 1990; 76: 295-300
-
(1990)
Br J Haematol
, vol.76
, pp. 295-300
-
-
Kontoghiorghes, G.J.1
Bartlett, A.N.2
Hoffbrand, A.V.3
-
99
-
-
0026680591
-
Reduction of tissue iron stores and normalisation of serum ferritin during treatment with the oral iron chelator L1 in thalassaemia intermedia
-
Olivieri NF, Koren G, Matsuii D, et al. Reduction of tissue iron stores and normalisation of serum ferritin during treatment with the oral iron chelator L1 in thalassaemia intermedia. Blood 1992; 79: 2741-8
-
(1992)
Blood
, vol.79
, pp. 2741-2748
-
-
Olivieri, N.F.1
Koren, G.2
Matsuii, D.3
-
100
-
-
0037125595
-
Comparison of effects of oral deferiprone and subcutaneous desferrioxamine on myocardial iron concentrations and ventricular function in beta-thalassaemia
-
Anderson LJ, Wonke B, Prescott E, et al. Comparison of effects of oral deferiprone and subcutaneous desferrioxamine on myocardial iron concentrations and ventricular function in beta-thalassaemia. Lancet 2002; 360: 516-20
-
(2002)
Lancet
, vol.360
, pp. 516-520
-
-
Anderson, L.J.1
Wonke, B.2
Prescott, E.3
-
101
-
-
0034601375
-
Hepatic iron concentration and total body iron stores in thalassaemia major
-
Angellucci E, Brittenham GM, McLaren CE, et al. Hepatic iron concentration and total body iron stores in thalassaemia major. N Engl J Med 2000; 343: 327-31
-
(2000)
N Engl J Med
, vol.343
, pp. 327-331
-
-
Angellucci, E.1
Brittenham, G.M.2
McLaren, C.E.3
-
102
-
-
0028862502
-
Liver iron stores in patients with secondary haemochromatosis under iron chelation therapy with deferoxamine or deferiprone
-
Nielsen P, Fischer R, Engelhardt R, et al. Liver iron stores in patients with secondary haemochromatosis under iron chelation therapy with deferoxamine or deferiprone. Br J Haematol 1995; 91: 827-33
-
(1995)
Br J Haematol
, vol.91
, pp. 827-833
-
-
Nielsen, P.1
Fischer, R.2
Engelhardt, R.3
-
103
-
-
0031770931
-
T2 relaxation time study of iron overload in β-thalassaemia
-
Mavrogeni SI, Gotsis ED, Markussis V, et al. T2 relaxation time study of iron overload in β-thalassaemia. MAGMA 1998; 6: 7-12
-
(1998)
MAGMA
, vol.6
, pp. 7-12
-
-
Mavrogeni, S.I.1
Gotsis, E.D.2
Markussis, V.3
-
104
-
-
18044399191
-
Cardiovascular T2-star (T2*) magnetic resonance for the early diagnosis of myocardial iron overload
-
Anderson LJ, Holden S, Davis B, et al. Cardiovascular T2-star (T2*) magnetic resonance for the early diagnosis of myocardial iron overload. Eur Heart J 2001; 22: 2171-9
-
(2001)
Eur Heart J
, vol.22
, pp. 2171-2179
-
-
Anderson, L.J.1
Holden, S.2
Davis, B.3
-
105
-
-
0033677772
-
The importance of non-transferrin bound iron in disorders of iron metabolism
-
Breuer W, Hershko C, Cabantchik ZI. The importance of non-transferrin bound iron in disorders of iron metabolism. Transfus Sci 2000; 23: 185-92
-
(2000)
Transfus Sci
, vol.23
, pp. 185-192
-
-
Breuer, W.1
Hershko, C.2
Cabantchik, Z.I.3
-
106
-
-
0029120697
-
Oral iron chelation therapy with deferiprone (L1): Monitoring of biochemical, drug and iron excretion changes
-
Kontoghiorghes GJ, Bartlett AN, Sheppard L, et al. Oral iron chelation therapy with deferiprone (L1): monitoring of biochemical, drug and iron excretion changes. Arzneimittel Forschung 1955; 45: 65-9
-
(1955)
Arzneimittel Forschung
, vol.45
, pp. 65-69
-
-
Kontoghiorghes, G.J.1
Bartlett, A.N.2
Sheppard, L.3
-
107
-
-
0005790852
-
Iron chelation in biochemistry and medicine
-
Rice-Evans C, editor. London: Rechelieu Press
-
Kontoghiorghes GJ. Iron chelation in biochemistry and medicine. In: Rice-Evans C, editor. Free radicals, oxidant stress and drug action. London: Rechelieu Press, 1982: 277-303
-
(1982)
Free Radicals, Oxidant Stress and Drug Action
, pp. 277-303
-
-
Kontoghiorghes, G.J.1
-
108
-
-
0027195024
-
Competition between deferiprone, desferrioxamine and other chelators for iron and the effect of other metals
-
Sheppard L, Kontoghiorghes GJ. Competition between deferiprone, desferrioxamine and other chelators for iron and the effect of other metals. Arzheimittel Forschung 1993; 43: 659-63
-
(1993)
Arzheimittel Forschung
, vol.43
, pp. 659-663
-
-
Sheppard, L.1
Kontoghiorghes, G.J.2
-
109
-
-
0023946136
-
Depletion of trace elements and acute occular toxicity induced by desferrioxamine in patients with thalassaemia
-
De Virgilis S, Cognia M, Turco MP, et al. Depletion of trace elements and acute occular toxicity induced by desferrioxamine in patients with thalassaemia. Arch Dis Child 1988; 63: 250-5
-
(1988)
Arch Dis Child
, vol.63
, pp. 250-255
-
-
De Virgilis, S.1
Cognia, M.2
Turco, M.P.3
-
110
-
-
0028630549
-
Zinc concentration in patients with iron overload receiving oral iron chelator 1,2-dimethyl-3-hydroxypyrid-4-one or desferrioxamine
-
Al-Refai FN, Wonke B, Wickens DG, et al. Zinc concentration in patients with iron overload receiving oral iron chelator 1,2-dimethyl-3-hydroxypyrid-4-one or desferrioxamine. J Clin Pathol 1994; 47: 657-60
-
(1994)
J Clin Pathol
, vol.47
, pp. 657-660
-
-
Al-Refai, F.N.1
Wonke, B.2
Wickens, D.G.3
-
111
-
-
0023275163
-
New synthetic approach and iron chelation studies of 1-alkyl-2-methyl-3-hydroxypyrid-4-ones
-
Kontoghiorghes GJ, Sheppard L, Chambers S. New synthetic approach and iron chelation studies of 1-alkyl-2-methyl-3-hydroxypyrid-4-ones. Arzneimittel Forschung 1987; 37: 1099-102
-
(1987)
Arzneimittel Forschung
, vol.37
, pp. 1099-1102
-
-
Kontoghiorghes, G.J.1
Sheppard, L.2
Chambers, S.3
-
112
-
-
0023552536
-
Pharmacokinetics of desferrioxamine and its aluminium chelates in patients on haemodialysis
-
Allain P, Chaleil D, Mauras Y, et al. Pharmacokinetics of desferrioxamine and its aluminium chelates in patients on haemodialysis. Clin Chim Acta 1987; 170: 331-8
-
(1987)
Clin Chim Acta
, vol.170
, pp. 331-338
-
-
Allain, P.1
Chaleil, D.2
Mauras, Y.3
-
113
-
-
0007546424
-
Therapeutic, pharmacological and toxicological aspects of metals and new chelating drugs
-
Kontoghiorghes GJ. Therapeutic, pharmacological and toxicological aspects of metals and new chelating drugs. Curr Top Mol Pharmacol 1993; 1: 189-211
-
(1993)
Curr Top Mol Pharmacol
, vol.1
, pp. 189-211
-
-
Kontoghiorghes, G.J.1
-
114
-
-
0022629886
-
The study of iron mobilisation from transferrin using α-ketohydroxy heteroaromatic chelators
-
Kontoghiorghes GJ. The study of iron mobilisation from transferrin using α-ketohydroxy heteroaromatic chelators. Biochim Biophys Acta 1986; 869: 141-6
-
(1986)
Biochim Biophys Acta
, vol.869
, pp. 141-146
-
-
Kontoghiorghes, G.J.1
-
115
-
-
0022568806
-
Iron mobilisation from lactoferrin by chelators at physiological pH
-
Kontoghiorghes GJ. Iron mobilisation from lactoferrin by chelators at physiological pH. Biochim Biophys Acta 1986; 882: 267-70
-
(1986)
Biochim Biophys Acta
, vol.882
, pp. 267-270
-
-
Kontoghiorghes, G.J.1
-
116
-
-
0023143039
-
Comparative study of iron mobilisation from haemosiderin, ferritin and iron (III) precipitates by chelators
-
Kontoghiorghes GJ, Chambers S, Hoffbrand AV. Comparative study of iron mobilisation from haemosiderin, ferritin and iron (III) precipitates by chelators. Biochem J 1987; 241: 87-92
-
(1987)
Biochem J
, vol.241
, pp. 87-92
-
-
Kontoghiorghes, G.J.1
Chambers, S.2
Hoffbrand, A.V.3
-
117
-
-
38249034939
-
Decreased solubilisation of ferritin iron and fresh iron (III) precipitate following repeated chelator treatments
-
Kontoghiorghes GJ. Decreased solubilisation of ferritin iron and fresh iron (III) precipitate following repeated chelator treatments. Inorg Chim Acta 1987; 138: 36-40
-
(1987)
Inorg Chim Acta
, vol.138
, pp. 36-40
-
-
Kontoghiorghes, G.J.1
-
118
-
-
7444249085
-
The biochemistry of desferrioxamine and its relation to iron metabolism
-
Keberle H. The biochemistry of desferrioxamine and its relation to iron metabolism. Ann N Y Acad Sci 1964; 119: 758-68
-
(1964)
Ann N Y Acad Sci
, vol.119
, pp. 758-768
-
-
Keberle, H.1
-
119
-
-
0027291099
-
Intravenous infusion pharmacokinetics of desferrioxamine in thalassaemia patients
-
Lee P, Mohammed N, Marshall RD, et al. Intravenous infusion pharmacokinetics of desferrioxamine in thalassaemia patients. Drug Metab Dispos 1993; 21: 640-4
-
(1993)
Drug Metab Dispos
, vol.21
, pp. 640-644
-
-
Lee, P.1
Mohammed, N.2
Marshall, R.D.3
-
120
-
-
0027080322
-
The effect of alpha-ketohydroxypyridine chelators on transferrin saturation in vitro and in vivo
-
Evans RW, Sharma M, Ogwang W, et al. The effect of alpha-ketohydroxypyridine chelators on transferrin saturation in vitro and in vivo. Drugs Today (Barc) 1992; 28 Suppl. A: 19-23
-
(1992)
Drugs Today (Barc)
, vol.28
, Issue.SUPPL. A
, pp. 19-23
-
-
Evans, R.W.1
Sharma, M.2
Ogwang, W.3
-
121
-
-
0023530083
-
Free radical and cytotoxic effects of chelators and their iron complexes in the hepatocyte
-
Mostert LJ, Van Dorst JA, Koster JF, et al. Free radical and cytotoxic effects of chelators and their iron complexes in the hepatocyte. Free Radic Res Commun 1987; 3: 379-88
-
(1987)
Free Radic Res Commun
, vol.3
, pp. 379-388
-
-
Mostert, L.J.1
Van Dorst, J.A.2
Koster, J.F.3
-
122
-
-
0025304783
-
The effect of novel 1-alkyl-3-hydroxy-2-methylpyrid-4-one chelators on uptake and release of iron from macrophages
-
Brock JH, Liceaga J, Arthur HML, et al. The effect of novel 1-alkyl-3-hydroxy-2-methylpyrid-4-one chelators on uptake and release of iron from macrophages. Am J Haematol 1990; 34: 21-5
-
(1990)
Am J Haematol
, vol.34
, pp. 21-25
-
-
Brock, J.H.1
Liceaga, J.2
Arthur, H.M.L.3
-
123
-
-
0025689038
-
Cellular iron metabolism in health and disease
-
Weinberg ED. Cellular iron metabolism in health and disease. Drug Metab Rev 1990; 22: 531-79
-
(1990)
Drug Metab Rev
, vol.22
, pp. 531-579
-
-
Weinberg, E.D.1
-
124
-
-
0017077213
-
Reassessment of the use of desferrioxamine B in iron overload
-
Proper RD, Shurin SB, Nathan DG. Reassessment of the use of desferrioxamine B in iron overload. N Engl J Med 1976; 294: 1421-3
-
(1976)
N Engl J Med
, vol.294
, pp. 1421-1423
-
-
Proper, R.D.1
Shurin, S.B.2
Nathan, D.G.3
-
125
-
-
0023877556
-
Acute visual and auditory neurotoxicity in patients with end-stage renal disease receiving desferrioxamine
-
Cases A, Velly J, Sabater J, et al. Acute visual and auditory neurotoxicity in patients with end-stage renal disease receiving desferrioxamine. Clin Nephrol 1988; 29: 176-8
-
(1988)
Clin Nephrol
, vol.29
, pp. 176-178
-
-
Cases, A.1
Velly, J.2
Sabater, J.3
-
126
-
-
0026571807
-
Pulmonary toxic effects of continous desferrioxamine administration in acute iron poisoning
-
Tenenbein M, Kowalski S, Sienko A, et al. Pulmonary toxic effects of continous desferrioxamine administration in acute iron poisoning. Lancet 1992; I: 699-701
-
(1992)
Lancet
, vol.1
, pp. 699-701
-
-
Tenenbein, M.1
Kowalski, S.2
Sienko, A.3
-
127
-
-
0025267012
-
Acute bone marrow aplasia associated with intravenous administration of deferoxamine (desferrioxamine)
-
Sofroniadou K, Drossou M, Foundoulaki M, et al. Acute bone marrow aplasia associated with intravenous administration of deferoxamine (desferrioxamine). Drug Saf 1990; 5 (2): 152-4
-
(1990)
Drug Saf
, vol.5
, Issue.2
, pp. 152-154
-
-
Sofroniadou, K.1
Drossou, M.2
Foundoulaki, M.3
-
128
-
-
0021329590
-
Prophylaxis of systemic yersiniasis in Thalassaemia major
-
Sharnetzky M, Konig R, Lamomek M, et al. Prophylaxis of systemic yersiniasis in Thalassaemia major [letter]. Lancet 1984; II: 791
-
(1984)
Lancet
, vol.2
, pp. 791
-
-
Sharnetzky, M.1
Konig, R.2
Lamomek, M.3
-
129
-
-
0029963993
-
Growth and development in thalassaemia major patients with severe bone lesions due to desferrioxamine
-
De Sanctis V, Pinamonti A, Di Palma A, et al. Growth and development in thalassaemia major patients with severe bone lesions due to desferrioxamine. Eur J Paediatr 1996; 155: 368-72
-
(1996)
Eur J Paediatr
, vol.155
, pp. 368-372
-
-
De Sanctis, V.1
Pinamonti, A.2
Di Palma, A.3
-
130
-
-
0024401997
-
Agranulocytosis and thrombocytopenia in a patient with Blackfan-Diamond anaemia during oral chelator trial
-
Hoffbrand AV, Bartlett A, Veys PA, et al. Agranulocytosis and thrombocytopenia in a patient with Blackfan-Diamond anaemia during oral chelator trial [letter]. Lancet 1989; II: 457
-
(1989)
Lancet
, vol.2
, pp. 457
-
-
Hoffbrand, A.V.1
Bartlett, A.2
Veys, P.A.3
-
131
-
-
0024403012
-
Prospects for effective oral iron chelation therapy in man with 1,2-dimethyl-3-hydroxypyrid-4-one and other alpha-ketohydroxypyridines
-
Kontoghiorghes GJ, Bartlett AH, Hoffbrand AV. Prospects for effective oral iron chelation therapy in man with 1,2-dimethyl-3-hydroxypyrid-4-one and other alpha-ketohydroxypyridines. Prog Clin Biol Res 1989; 309: 107-14
-
(1989)
Prog Clin Biol Res
, vol.309
, pp. 107-114
-
-
Kontoghiorghes, G.J.1
Bartlett, A.H.2
Hoffbrand, A.V.3
-
132
-
-
0031011172
-
Deferiprone-induced agranulocytosis: A critical review of five rechallenged cases
-
Loebstein R, Diav-Citrin O, Atanackovic G, et al. Deferiprone-induced agranulocytosis: a critical review of five rechallenged cases. Clin Drug Invest 1997; 13: 345-9
-
(1997)
Clin Drug Invest
, vol.13
, pp. 345-349
-
-
Loebstein, R.1
Diav-Citrin, O.2
Atanackovic, G.3
-
133
-
-
0031046747
-
Agranulocytosis, arthritis and systemic vasculitis in a patient receiving the oral iron chelator L1 (deferiprone)
-
Castriota-Scanderbeg A, Sacco M. Agranulocytosis, arthritis and systemic vasculitis in a patient receiving the oral iron chelator L1 (deferiprone). Br J Haematol 1997; 96: 254-5
-
(1997)
Br J Haematol
, vol.96
, pp. 254-255
-
-
Castriota-Scanderbeg, A.1
Sacco, M.2
-
134
-
-
0036068230
-
The safety and effectiveness of deferiprone in a large-scale, 3-year study in Italian patients
-
Ceci A, Baiardi P, Felisi M, et al. The safety and effectiveness of deferiprone in a large-scale, 3-year study in Italian patients. Br J Haematol 2002; 118: 330-6
-
(2002)
Br J Haematol
, vol.118
, pp. 330-336
-
-
Ceci, A.1
Baiardi, P.2
Felisi, M.3
-
135
-
-
0029825581
-
Long term treatment of transfusional iron overload with the oral iron chelator deferiprone (L1): A Dutch multicentre trial
-
Kersten MJ, Lange R, Smeets MEP, et al. Long term treatment of transfusional iron overload with the oral iron chelator deferiprone (L1): a Dutch multicentre trial. Ann Haematol 1996; 73: 247-52
-
(1996)
Ann Haematol
, vol.73
, pp. 247-252
-
-
Kersten, M.J.1
Lange, R.2
Smeets, M.E.P.3
-
136
-
-
0025130087
-
Long-term trial with the oral iron chelator 1,2-dimethyl-3-hydroxypyrid-4-one (L1)
-
Bartlett AN, Hoffbrand AV, Kontoghiorghes GJ. Long-term trial with the oral iron chelator 1,2-dimethyl-3-hydroxypyrid-4-one (L1). Br J Haematol 1990; 76: 301-9
-
(1990)
Br J Haematol
, vol.76
, pp. 301-309
-
-
Bartlett, A.N.1
Hoffbrand, A.V.2
Kontoghiorghes, G.J.3
-
137
-
-
0020577339
-
Ocular toxicity of high dose intravenous desferrioxamine
-
Davies SC, Marcus RE, Hungerford JL, et al. Ocular toxicity of high dose intravenous desferrioxamine. Lancet 1983; II: 181-4
-
(1983)
Lancet
, vol.2
, pp. 181-184
-
-
Davies, S.C.1
Marcus, R.E.2
Hungerford, J.L.3
-
138
-
-
0022649329
-
Ocular toxicity of desferrioxamine: Light microscopic histochemical and ultrastructural findings
-
Rahi AHS, Hungerford JL, Ahmed AI. Ocular toxicity of desferrioxamine: light microscopic histochemical and ultrastructural findings. Br J Ophthal 1986; 70: 373-81
-
(1986)
Br J Ophthal
, vol.70
, pp. 373-381
-
-
Rahi, A.H.S.1
Hungerford, J.L.2
Ahmed, A.I.3
-
140
-
-
0021321289
-
Visual loss in patient on high dose subcutaneous desferrioxamine
-
Borgna-Pignatti C, De Stefano P, Broglia AM. Visual loss in patient on high dose subcutaneous desferrioxamine. Lancet 1984; I: 68
-
(1984)
Lancet
, vol.1
, pp. 68
-
-
Borgna-Pignatti, C.1
De Stefano, P.2
Broglia, A.M.3
-
141
-
-
0027053573
-
Long term assessment of efficacy and toxicity of L1 (1,2-dimethyl-3-hydroxypyrid-4-one) in transfusion dependent thalassaemia: Indian trial
-
Agarwal MB, Gupta SS, Viswanathan C, et al. Long term assessment of efficacy and toxicity of L1 (1,2-dimethyl-3-hydroxypyrid-4-one) in transfusion dependent thalassaemia: Indian trial. Drugs Today (Barc) 1992; 28 Suppl. A: 107-14
-
(1992)
Drugs Today (Barc)
, vol.28
, Issue.SUPPL. A
, pp. 107-114
-
-
Agarwal, M.B.1
Gupta, S.S.2
Viswanathan, C.3
-
142
-
-
0028364145
-
Arthropathy in thalassaemia patients receiving deferiprone
-
Berkovitch M, Laxer RM, Inman R, et al. Arthropathy in thalassaemia patients receiving deferiprone. Lancet 1994; 343: 1471-2
-
(1994)
Lancet
, vol.343
, pp. 1471-1472
-
-
Berkovitch, M.1
Laxer, R.M.2
Inman, R.3
-
143
-
-
0021874024
-
M. Acute deafness and desferrioxamine
-
Guerin A, London G, Marchais S, et al. M. Acute deafness and desferrioxamine. Lancet 1985; II: 39-40
-
(1985)
Lancet
, vol.2
, pp. 39-40
-
-
Guerin, A.1
London, G.2
Marchais, S.3
-
144
-
-
0025822062
-
Desferrioxamine enhances the haemopoietic response to erythropoietin but adverse events are common
-
Roger SD, Stewart JH, Harris DCU. Desferrioxamine enhances the haemopoietic response to erythropoietin but adverse events are common. Nephron 1991; 58: 33-6
-
(1991)
Nephron
, vol.58
, pp. 33-36
-
-
Roger, S.D.1
Stewart, J.H.2
Harris, D.C.U.3
-
145
-
-
0037579289
-
Treatment of rheumatoid arthritis with desferrioxamine: Relation between stores of iron before treatment and side effects
-
Polson RJ, Jawed A, Bomford A, et al. Treatment of rheumatoid arthritis with desferrioxamine: relation between stores of iron before treatment and side effects. Br Med J (Clin Res Ed) 1985; 291: 448
-
(1985)
Br Med J (Clin Res Ed)
, vol.291
, pp. 448
-
-
Polson, R.J.1
Jawed, A.2
Bomford, A.3
-
146
-
-
0025276120
-
Comparison of deferoxamine pharmacokinetics between asymptomatic thalassemic children and those exhibiting severe neurotoxicity
-
Bentur Y, Koren G, Tegoro A, et al. Comparison of deferoxamine pharmacokinetics between asymptomatic thalassemic children and those exhibiting severe neurotoxicity. Clin Pharmacol Ther 1990; 47: 478-82
-
(1990)
Clin Pharmacol Ther
, vol.47
, pp. 478-482
-
-
Bentur, Y.1
Koren, G.2
Tegoro, A.3
-
147
-
-
0021793920
-
Cerebral and ocular toxicity induced by desferrioxamine
-
Blake DR, Winyard P, Lunec J, et al. Cerebral and ocular toxicity induced by desferrioxamine. Q J Med 1985; 56: 345-55
-
(1985)
Q J Med
, vol.56
, pp. 345-355
-
-
Blake, D.R.1
Winyard, P.2
Lunec, J.3
-
148
-
-
0025344815
-
Pulmonary syndrome in patients with thalassaemia major receiving intravenous deferoxamine infusions
-
Freedman MH, Grisaru D, Olivieri N, et al. Pulmonary syndrome in patients with thalassaemia major receiving intravenous deferoxamine infusions. Am J Dis Child 1990; 144: 565-9
-
(1990)
Am J Dis Child
, vol.144
, pp. 565-569
-
-
Freedman, M.H.1
Grisaru, D.2
Olivieri, N.3
-
149
-
-
0031859182
-
Liver iron fibrosis during long-term treatment with deferiprone in Swiss thalassaemic patients
-
Tondury P, Zimmerman A, Nielsen P, et al. Liver iron fibrosis during long-term treatment with deferiprone in Swiss thalassaemic patients. Br J Haematol 1998; 101: 413-5
-
(1998)
Br J Haematol
, vol.101
, pp. 413-415
-
-
Tondury, P.1
Zimmerman, A.2
Nielsen, P.3
-
150
-
-
0036721452
-
Lack of progressive hepatic fibrosis during long-term therapy with deferiprone in subjects with transfusion-dependent beta-thalassemia
-
Wanless IR, Sweeney G, Dhillon AP, et al. Lack of progressive hepatic fibrosis during long-term therapy with deferiprone in subjects with transfusion-dependent beta-thalassemia. Blood 2002; 100: 1566-9
-
(2002)
Blood
, vol.100
, pp. 1566-1569
-
-
Wanless, I.R.1
Sweeney, G.2
Dhillon, A.P.3
-
151
-
-
0023708159
-
Deferoxamine-induced growth retardation in patients with thalassaemia major
-
De Virgidis S, Cognie M, Frau F, et al. Deferoxamine-induced growth retardation in patients with thalassaemia major. J Pediatr 1988; 113: 661-9
-
(1988)
J Pediatr
, vol.113
, pp. 661-669
-
-
De Virgidis, S.1
Cognie, M.2
Frau, F.3
-
153
-
-
84920243243
-
Desferrioxamine and systemic yersiniosis
-
Robins-Browne RM, Pipic JK. Desferrioxamine and systemic yersiniosis [letter]. Lancet 1983; II: 1372
-
(1983)
Lancet
, vol.2
, pp. 1372
-
-
Robins-Browne, R.M.1
Pipic, J.K.2
-
154
-
-
0021329590
-
Prophylaxis of systemic yersiniosis in thalassaemia major
-
Scharnetzky M, Konig R, Lakomek M, et al. Prophylaxis of systemic yersiniosis in thalassaemia major [letter]. Lancet 1984: I: 791
-
(1984)
Lancet
, vol.1
, pp. 791
-
-
Scharnetzky, M.1
Konig, R.2
Lakomek, M.3
-
155
-
-
0021756603
-
Yersinia pseudoturberculosis septicaemia in thalassaemia major
-
Gordts B, Rummens E, De Meirleir L, et al. Yersinia pseudoturberculosis septicaemia in thalassaemia major. Lancet 1984; I: 41-2
-
(1984)
Lancet
, vol.1
, pp. 41-42
-
-
Gordts, B.1
Rummens, E.2
De Meirleir, L.3
-
156
-
-
0023044496
-
Yersinia and iron overload
-
Kelly D, Price E, Wright V, et al. Yersinia and iron overload. BMJ 1986; 292: 413
-
(1986)
BMJ
, vol.292
, pp. 413
-
-
Kelly, D.1
Price, E.2
Wright, V.3
-
157
-
-
0036426806
-
Effects of deferiprone on immune status and cytokine pattern in thalassaemia major
-
Del Vecchio GC, Schettini F, Placente L, et al. Effects of deferiprone on immune status and cytokine pattern in thalassaemia major. Acta Haematol 2002; 108: 144-9
-
(2002)
Acta Haematol
, vol.108
, pp. 144-149
-
-
Del Vecchio, G.C.1
Schettini, F.2
Placente, L.3
-
158
-
-
0032820582
-
Sequential use of L1 and desferrioxamine in primary school children with thalassaemia major in Turkey
-
Aydinok Y, Nisli G, Kavakli K, et al. Sequential use of L1 and desferrioxamine in primary school children with thalassaemia major in Turkey. Acta Haematol 1999; 102: 17-21
-
(1999)
Acta Haematol
, vol.102
, pp. 17-21
-
-
Aydinok, Y.1
Nisli, G.2
Kavakli, K.3
-
159
-
-
0024834620
-
Effects of deferoxamine, feroxamine and iron on experimental mucormycosis (zygomycosis)
-
Van Cutsem J, Boelaert JR. Effects of deferoxamine, feroxamine and iron on experimental mucormycosis (zygomycosis). Kidney Int 1989; 36: 1061-8
-
(1989)
Kidney Int
, vol.36
, pp. 1061-1068
-
-
Van Cutsem, J.1
Boelaert, J.R.2
-
160
-
-
0022197562
-
Thrombocytopenia associated with intravenous desferrioxamine
-
Walker JA, Sherman RA, Eisinger RP. Thrombocytopenia associated with intravenous desferrioxamine. Am J Kidney Dis 1985; 6: 254-6
-
(1985)
Am J Kidney Dis
, vol.6
, pp. 254-256
-
-
Walker, J.A.1
Sherman, R.A.2
Eisinger, R.P.3
-
161
-
-
0003996982
-
Aluminium-related osteomalagia: Clinical response to desferrioxamine
-
Nebeker HG, Milliner DS, Ott SA, et al. Aluminium-related osteomalagia: clinical response to desferrioxamine [abstract]. Kidney Int 1984; 25: 173
-
(1984)
Kidney Int
, vol.25
, pp. 173
-
-
Nebeker, H.G.1
Milliner, D.S.2
Ott, S.A.3
-
164
-
-
0020561803
-
Rapid desensitisation for desferrioxamine anaphylactic reactions
-
Bousquet J, Navarpo M, Robert G, et al. Rapid desensitisation for desferrioxamine anaphylactic reactions. Lancet 1983; II: 859-60
-
(1983)
Lancet
, vol.2
, pp. 859-860
-
-
Bousquet, J.1
Navarpo, M.2
Robert, G.3
-
165
-
-
0019436308
-
Rapid desensitisation for desferrioxamine anaphylactic reaction
-
Miller KB, Rosenwasser LJ, Bessette JA, et al. Rapid desensitisation for desferrioxamine anaphylactic reaction [letter]. Lancet 1987; I: 1059
-
(1987)
Lancet
, vol.1
, pp. 1059
-
-
Miller, K.B.1
Rosenwasser, L.J.2
Bessette, J.A.3
-
166
-
-
0018759857
-
Acute renal insufficiency occurring during intravenous desferrioxamine therapy
-
Batey R, Scott J, Jain S, et al. Acute renal insufficiency occurring during intravenous desferrioxamine therapy. Scand J Haematol 1979; 22: 277-9
-
(1979)
Scand J Haematol
, vol.22
, pp. 277-279
-
-
Batey, R.1
Scott, J.2
Jain, S.3
-
167
-
-
4244188786
-
Renal abnormalities in patients with β-thalassaemia major treated with chronic subcutaneous deferoxamine
-
Wayne AS, Rosenblum ND, Sallan D, et al. Renal abnormalities in patients with β-thalassaemia major treated with chronic subcutaneous deferoxamine [abstract]. Blood 1993; 82 Suppl. 1: 476a
-
(1993)
Blood
, vol.82
, Issue.SUPPL. 1
-
-
Wayne, A.S.1
Rosenblum, N.D.2
Sallan, D.3
-
168
-
-
0023611979
-
Orally active α-ketohydroxypyridine iron chelators: Effects on iron and other metal mobilisations
-
Kontoghiorghes GJ. Orally active α-ketohydroxypyridine iron chelators: effects on iron and other metal mobilisations. Acta Haematol 1987; 78: 212-6
-
(1987)
Acta Haematol
, vol.78
, pp. 212-216
-
-
Kontoghiorghes, G.J.1
-
169
-
-
0024355546
-
Oxygen-based free radical generation by ferrous ions and desferioxamine
-
Klebanoff SJ, Waltersdorph AM, Michel BR, et al. Oxygen-based free radical generation by ferrous ions and desferioxamine. J Biol Chem 1989; 254: 19765-71
-
(1989)
J Biol Chem
, vol.254
, pp. 19765-19771
-
-
Klebanoff, S.J.1
Waltersdorph, A.M.2
Michel, B.R.3
-
170
-
-
0027051554
-
Cytotoxic mechanisms of iron chelators
-
Ganeshaguru K, Lally KM, Piga A, et al. Cytotoxic mechanisms of iron chelators. Drugs Today (Barc) 1992; 28 Suppl. A: 29-34
-
(1992)
Drugs Today (Barc)
, vol.28
, Issue.SUPPL. A
, pp. 29-34
-
-
Ganeshaguru, K.1
Lally, K.M.2
Piga, A.3
-
171
-
-
0021259518
-
Deferrioxaraine: A reversible S-phase inhibitor of human lymphocyte proliferation
-
Lederman HM, Cohen A, Lee JWW, et al. Deferrioxaraine: a reversible S-phase inhibitor of human lymphocyte proliferation. Blood 1984; 64: 748-53
-
(1984)
Blood
, vol.64
, pp. 748-753
-
-
Lederman, H.M.1
Cohen, A.2
Lee, J.W.W.3
-
172
-
-
0018777993
-
Studies in desferrioxamine and ferrioxamine iron metabolism in normal and iron loaded subjects
-
Summers MR, Jacobs A, Tudway D, et al. Studies in desferrioxamine and ferrioxamine iron metabolism in normal and iron loaded subjects. Br J Haematol 1979; 42: 547-55
-
(1979)
Br J Haematol
, vol.42
, pp. 547-555
-
-
Summers, M.R.1
Jacobs, A.2
Tudway, D.3
-
173
-
-
0021357262
-
Desferrioxamine to improve cardiac function in iron-overloaded patients with thalassaemia major
-
Marcus RE, Davies SG, Bantock HM, et al. Desferrioxamine to improve cardiac function in iron-overloaded patients with thalassaemia major. Lancet 1984; I: 392-3
-
(1984)
Lancet
, vol.1
, pp. 392-393
-
-
Marcus, R.E.1
Davies, S.G.2
Bantock, H.M.3
-
174
-
-
0021225166
-
Depletion of excessive liver iron stores with desferrioxamine
-
Cohen A, Martin M, Schwartz E. Depletion of excessive liver iron stores with desferrioxamine. Br J Haematol 1984; 58: 369-73
-
(1984)
Br J Haematol
, vol.58
, pp. 369-373
-
-
Cohen, A.1
Martin, M.2
Schwartz, E.3
-
176
-
-
0018874982
-
Iron chelation with oral desferrioxamine
-
Callender ST, Weatherall DJ. Iron chelation with oral desferrioxamine [letter]. Lancet 1980; II: 689
-
(1980)
Lancet
, vol.2
, pp. 689
-
-
Callender, S.T.1
Weatherall, D.J.2
-
177
-
-
0023877695
-
L1 (1,2-dimethyl-3-hydroxypyrid-4-one)
-
Kontoghiorghes GJ. L1 (1,2-dimethyl-3-hydroxypyrid-4-one). Drugs Future 1988; 13: 413-5
-
(1988)
Drugs Future
, vol.13
, pp. 413-415
-
-
Kontoghiorghes, G.J.1
-
178
-
-
0023009651
-
Cytotoxic effects of the lipophilic iron chelator omadine
-
Kontoghiorghes GJ, Piga A, Hoffbrand A. Cytotoxic effects of the lipophilic iron chelator omadine. FEBS Lett 1986; 204: 208-12
-
(1986)
FEBS Lett
, vol.204
, pp. 208-212
-
-
Kontoghiorghes, G.J.1
Piga, A.2
Hoffbrand, A.3
-
179
-
-
0025007785
-
Pharmacokinetic studies in humans with the oral iron chelator 1,2-dimethyl-3-hydroxypyrid-4-one
-
Kontoghiorghes GJ, Goddard JG, Bartlett AN, et al. Pharmacokinetic studies in humans with the oral iron chelator 1,2-dimethyl-3-hydroxypyrid-4-one. Clin Pharmacol Ther 1990; 48: 255-61
-
(1990)
Clin Pharmacol Ther
, vol.48
, pp. 255-261
-
-
Kontoghiorghes, G.J.1
Goddard, J.G.2
Bartlett, A.N.3
-
180
-
-
0027056363
-
Synthesis and metabolism of L1 and other novel alpha-ketohydroxypyridine iron chelators and their metal complexes
-
Sheppard L, Kontoghiorghes GJ. Synthesis and metabolism of L1 and other novel alpha-ketohydroxypyridine iron chelators and their metal complexes. Drugs Today (Barc) 1992; 28 Suppl. A: 3-10
-
(1992)
Drugs Today (Barc)
, vol.28
, Issue.SUPPL. A
, pp. 3-10
-
-
Sheppard, L.1
Kontoghiorghes, G.J.2
-
181
-
-
0026001164
-
Relationship between the pharmacokinetics and iron excretion pharmacodynamics of the new oral iron chelator 1,2-dimethyl-3-hydroxypyrid-4-one in patients with thalassaemia
-
Matsui D, Klein J, Hermann C, et al. Relationship between the pharmacokinetics and iron excretion pharmacodynamics of the new oral iron chelator 1,2-dimethyl-3-hydroxypyrid-4-one in patients with thalassaemia. Clin Pharmacol Ther 1991; 50: 294-8
-
(1991)
Clin Pharmacol Ther
, vol.50
, pp. 294-298
-
-
Matsui, D.1
Klein, J.2
Hermann, C.3
-
183
-
-
0033025760
-
An investigation into variability in the therapeutic response to deferiprone in patients with thalassaemia major
-
Diav-Citrin O, Atanackovic G, Koren G. An investigation into variability in the therapeutic response to deferiprone in patients with thalassaemia major. Ther Drug Monit 1999; 21: 74-81
-
(1999)
Ther Drug Monit
, vol.21
, pp. 74-81
-
-
Diav-Citrin, O.1
Atanackovic, G.2
Koren, G.3
-
184
-
-
0023214937
-
1,2-Dimethyl-3-hydroxypyrid-4-one, on orally active chelator for the treatment of transfusional iron overload
-
Kontoghiorghes GJ, Aldouri MA, Sheppard LN, et al. 1,2-Dimethyl-3-hydroxypyrid-4-one, on orally active chelator for the treatment of transfusional iron overload. Lancet 1987; I: 1294-5
-
(1987)
Lancet
, vol.1
, pp. 1294-1295
-
-
Kontoghiorghes, G.J.1
Aldouri, M.A.2
Sheppard, L.N.3
-
185
-
-
0025066690
-
Comparison of oral iron chelator L1 and desferrioxamine in iron loaded patients
-
Olivieri NF, Koren G, Hermann C, et al. Comparison of oral iron chelator L1 and desferrioxamine in iron loaded patients. Lancet 1990; II: 1275-9
-
(1990)
Lancet
, vol.2
, pp. 1275-1279
-
-
Olivieri, N.F.1
Koren, G.2
Hermann, C.3
-
186
-
-
0026668939
-
Long term assessment of efficacy and safety of L1, an oral iron chelator in transfusion dependent thalassaemia: Indian trial
-
Agarwal MB, Gupta SS, Viswanathan C, et al. Long term assessment of efficacy and safety of L1, an oral iron chelator in transfusion dependent thalassaemia: Indian trial. Br J Haematol 1992; 82: 460-6
-
(1992)
Br J Haematol
, vol.82
, pp. 460-466
-
-
Agarwal, M.B.1
Gupta, S.S.2
Viswanathan, C.3
-
187
-
-
0025605569
-
L1 (1,2-dimethyl-3-hydroxypyrid-4-one) for oral iron chelation in patients with B -thalassaemia major
-
Tondury P, Kontoghiorghes GJ, Ridolfi-Luthy R, et al. L1 (1,2-dimethyl-3-hydroxypyrid-4-one) for oral iron chelation in patients with B -thalassaemia major. Br J Haematol. 1990; 76: 550-3
-
(1990)
Br J Haematol
, vol.76
, pp. 550-553
-
-
Tondury, P.1
Kontoghiorghes, G.J.2
Ridolfi-Luthy, R.3
-
188
-
-
0027093057
-
Long term treatment of transfusion hemosiderosis with the oral iron chelator L1
-
Goudsmit R, Kersten MJ. Long term treatment of transfusion hemosiderosis with the oral iron chelator L1. Drugs Today (Barc) 1992; 28 Suppl. A: 133-5
-
(1992)
Drugs Today (Barc)
, vol.28
, Issue.SUPPL. A
, pp. 133-135
-
-
Goudsmit, R.1
Kersten, M.J.2
-
189
-
-
0027066787
-
Iron overload in polytransfused patients with MDS: Use of L1 for oral iron chelation
-
Jaeger M, Aul C, Sohngen D, et al. Iron overload in polytransfused patients with MDS: use of L1 for oral iron chelation. Drugs Today (Barc) 1992; 28 Suppl. A: 143-7
-
(1992)
Drugs Today (Barc)
, vol.28
, Issue.SUPPL. A
, pp. 143-147
-
-
Jaeger, M.1
Aul, C.2
Sohngen, D.3
-
190
-
-
0027080324
-
L1 efficacy and toxicity in poorly compliant and for refractory to desferrioxamine thalassaemia patients: Interim report
-
Carnelli V, Spadaro C, Stefano V, et al. L1 efficacy and toxicity in poorly compliant and for refractory to desferrioxamine thalassaemia patients: interim report. Drugs Today (Barc) 1992; 28 Suppl. A: 119-21
-
(1992)
Drugs Today (Barc)
, vol.28
, Issue.SUPPL. A
, pp. 119-121
-
-
Carnelli, V.1
Spadaro, C.2
Stefano, V.3
-
191
-
-
0028345040
-
Iron balance and dose response studies of the oral iron chelator 1,2-dimethyl-3-hydroxypyrid-4-one (L1) in iron loaded patients with sickle cell disease
-
Collins AF, Fassos FF, Stobie S, et al. Iron balance and dose response studies of the oral iron chelator 1,2-dimethyl-3-hydroxypyrid-4-one (L1) in iron loaded patients with sickle cell disease. Blood 1994; 83: 2329-3
-
(1994)
Blood
, vol.83
, pp. 2329-2323
-
-
Collins, A.F.1
Fassos, F.F.2
Stobie, S.3
-
192
-
-
0034044427
-
Chelation therapy in patients with thalassaemia using the orally active iron chelator deferiprone (L1)
-
Rombos Y, Tzanetea R, Konstantopoulos K, et al. Chelation therapy in patients with thalassaemia using the orally active iron chelator deferiprone (L1). Haematologica 2000; 85: 115-7
-
(2000)
Haematologica
, vol.85
, pp. 115-117
-
-
Rombos, Y.1
Tzanetea, R.2
Konstantopoulos, K.3
-
194
-
-
0031873538
-
Oral iron chelating therapy: A single centre interim report on deferiprone (L1) in thalassemia
-
Mazza P, Amurri B, Lazzari G, et al. Oral iron chelating therapy: a single centre interim report on deferiprone (L1) in thalassemia. Haematologica 1998; 83: 496-501
-
(1998)
Haematologica
, vol.83
, pp. 496-501
-
-
Mazza, P.1
Amurri, B.2
Lazzari, G.3
-
195
-
-
0033693910
-
The Sydney children's hospital experience with the oral iron chelator deferiprone (L1)
-
Berdoukas V, Bohane T, Eagle C, et al. The Sydney children's hospital experience with the oral iron chelator deferiprone (L1). Transfus Sci 2000; 23: 239-40
-
(2000)
Transfus Sci
, vol.23
, pp. 239-240
-
-
Berdoukas, V.1
Bohane, T.2
Eagle, C.3
-
196
-
-
0031848963
-
Effect of oral iron chetator L1 in iron absorption in man
-
Dresow B, Fischer R, Nielsen P, et al. Effect of oral iron chetator L1 in iron absorption in man. Ann N Y Acad Sci 1998; 850: 466-8
-
(1998)
Ann N Y Acad Sci
, vol.850
, pp. 466-468
-
-
Dresow, B.1
Fischer, R.2
Nielsen, P.3
-
197
-
-
0021914999
-
New orally active iron chelators
-
Kontoghiorghes GJ. New orally active iron chelators. Lancet 1985; II: 817
-
(1985)
Lancet
, vol.2
, pp. 817
-
-
Kontoghiorghes, G.J.1
-
198
-
-
0005839008
-
Intensive chelation and iron balance studies using oral 1,2-dimethyl-3-hydroxypyrid-4-one (L1) in man
-
Kontoghiorghes GJ, Bartlett AN, Hoffbrand AV, et al. Intensive chelation and iron balance studies using oral 1,2-dimethyl-3-hydroxypyrid-4-one (L1) in man [abstract]. Br J Haematol 1990; 74 Suppl. 1: 10
-
(1990)
Br J Haematol
, vol.74
, Issue.SUPPL. 1
, pp. 10
-
-
Kontoghiorghes, G.J.1
Bartlett, A.N.2
Hoffbrand, A.V.3
-
199
-
-
0038254841
-
-
Adverse Drug Reaction Centre. Information No.2. Oct
-
Ciba Report on Desferal. Adverse Drug Reaction Centre. Information No.2. 1965 Oct: 1-38
-
(1965)
Ciba Report on Desferal
, pp. 1-38
-
-
-
200
-
-
0031425503
-
Salivary measurement of deferiprone concentrations and correlation with serum levels
-
Pope E, Berkovitch M, Klein J, et al. Salivary measurement of deferiprone concentrations and correlation with serum levels. Ther Drug Monit 1997; 19: 95-7
-
(1997)
Ther Drug Monit
, vol.19
, pp. 95-97
-
-
Pope, E.1
Berkovitch, M.2
Klein, J.3
-
201
-
-
0032771863
-
Efficacy and side effects of deferiprone (L1) in thalassaemia patients not compliant with desferrioxamine
-
Taher A, Chamoun FM, Koussa S, et al. Efficacy and side effects of deferiprone (L1) in thalassaemia patients not compliant with desferrioxamine. Acta Haematol 1999; 101: 173-7
-
(1999)
Acta Haematol
, vol.101
, pp. 173-177
-
-
Taher, A.1
Chamoun, F.M.2
Koussa, S.3
-
202
-
-
0036245525
-
Effect of iron chelation therapy with deferiprone (L1) on the psychosocial status of thalassaemia patients
-
Zahet L, Murad FH, Alameddine R, et al. Effect of iron chelation therapy with deferiprone (L1) on the psychosocial status of thalassaemia patients. Haematologia 2002; 31: 333-9
-
(2002)
Haematologia
, vol.31
, pp. 333-339
-
-
Zahet, L.1
Murad, F.H.2
Alameddine, R.3
-
203
-
-
0026643003
-
Efficacy and possible adverse effects of the oral iron chelator 1,2-dimethyl-3-hydroxypyrid-4-one (L1) in thalassaemia major
-
Al-Refai FN, Wonke B, Hoffbrand AV, et al. Efficacy and possible adverse effects of the oral iron chelator 1,2-dimethyl-3-hydroxypyrid-4-one (L1) in thalassaemia major. Blood 1992; 80: 593-9
-
(1992)
Blood
, vol.80
, pp. 593-599
-
-
Al-Refai, F.N.1
Wonke, B.2
Hoffbrand, A.V.3
-
204
-
-
0028503628
-
Treatment of iron overload states with oral administration of the chelator L1
-
Cermak J, Brabec V. Treatment of iron overload states with oral administration of the chelator L1. Vnitr Lek 1994; 40: 586-90
-
(1994)
Vnitr Lek
, vol.40
, pp. 586-590
-
-
Cermak, J.1
Brabec, V.2
-
205
-
-
0029094988
-
Efficacy and safety of oral iron chelating agent deferiprone in beta-thalassaemia and hemoglobin E-beta thalassemia
-
Adhikari D, Roy TB, Biswas A, et al. Efficacy and safety of oral iron chelating agent deferiprone in beta-thalassaemia and hemoglobin E-beta thalassemia. Indian Pediatr 1995; 32: 855-61
-
(1995)
Indian Pediatr
, vol.32
, pp. 855-861
-
-
Adhikari, D.1
Roy, T.B.2
Biswas, A.3
-
206
-
-
0034202415
-
A trial of deferiprone in transfusion-dependent iron overloaded children
-
Lucas GN, Perera BJ, Foneka EA, et al. A trial of deferiprone in transfusion-dependent iron overloaded children. Ceylon Med J 2000; 45: 71-4
-
(2000)
Ceylon Med J
, vol.45
, pp. 71-74
-
-
Lucas, G.N.1
Perera, B.J.2
Foneka, E.A.3
-
207
-
-
0024801405
-
Drug metabolism by leukocytes and its role in drug-induced Lupus and other idiosyncratic drug reactions
-
Uetrecht JP. Drug metabolism by leukocytes and its role in drug-induced Lupus and other idiosyncratic drug reactions. Toxicology 1990; 20: 213-35
-
(1990)
Toxicology
, vol.20
, pp. 213-235
-
-
Uetrecht, J.P.1
-
208
-
-
0027131485
-
G-CSF levels during spontaneous recovery from drug-induced agranulocytosis
-
Fugata S, Murakami Y, Kuma K, et al. G-CSF levels during spontaneous recovery from drug-induced agranulocytosis [letter]. Lancet 1993; 342; 1495: 242
-
(1993)
Lancet
, vol.342
, Issue.1495
, pp. 242
-
-
Fugata, S.1
Murakami, Y.2
Kuma, K.3
-
210
-
-
0026507913
-
Advances in oral iron chelation in man
-
Kontoghiorghes GJ. Advances in oral iron chelation in man. Int J Haematol 1992; 55: 27-38
-
(1992)
Int J Haematol
, vol.55
, pp. 27-38
-
-
Kontoghiorghes, G.J.1
-
211
-
-
0022539184
-
Dose response studies using desferrioxamine and orally active chelators in a mouse model
-
Kontoghiorghes GJ. Dose response studies using desferrioxamine and orally active chelators in a mouse model. Scand J Haematol 1986; 37: 63-70
-
(1986)
Scand J Haematol
, vol.37
, pp. 63-70
-
-
Kontoghiorghes, G.J.1
-
212
-
-
0022597473
-
Orally active α-ketohydroxy pyridine iron chelators intended for clinical use: In vivo studies in rabbits
-
Kontoghiorghes GJ, Hoffbrand AV. Orally active α-ketohydroxy pyridine iron chelators intended for clinical use: in vivo studies in rabbits. Br J Haematol 1986; 62: 607-13
-
(1986)
Br J Haematol
, vol.62
, pp. 607-613
-
-
Kontoghiorghes, G.J.1
Hoffbrand, A.V.2
-
213
-
-
0031784438
-
Combined therapy with deferiprone and deferoxamine
-
Wonke B, Wright C, Hoffbrand AV. Combined therapy with deferiprone and deferoxamine. Br J Haematol 1998; 103: 361-4
-
(1998)
Br J Haematol
, vol.103
, pp. 361-364
-
-
Wonke, B.1
Wright, C.2
Hoffbrand, A.V.3
-
214
-
-
0037431883
-
Deferiprone versus desferrioxamine in thalassaemia, and T2* validation and utility
-
Kontoghiorghes GJ, Kolnagou A. Deferiprone versus desferrioxamine in thalassaemia, and T2* validation and utility. Lancet 2003; 361: 184
-
(2003)
Lancet
, vol.361
, pp. 184
-
-
Kontoghiorghes, G.J.1
Kolnagou, A.2
-
215
-
-
18444390877
-
Deferiprone versus deferoxamine in patients with thalassaemia major: A randomised clinical trial
-
Maggio A, D'Amico G, Morabito A, et al. Deferiprone versus deferoxamine in patients with thalassaemia major: a randomised clinical trial. Blood Cells Mol Dis 2002; 28: 196-208
-
(2002)
Blood Cells Mol Dis
, vol.28
, pp. 196-208
-
-
Maggio, A.1
D'Amico, G.2
Morabito, A.3
-
216
-
-
0020664836
-
Deficient sulphoxidation status in D-penicillamine toxicity
-
Panayi GS, HustonG, Shah RR. Deficient sulphoxidation status in D-penicillamine toxicity. Lancet 1983; I: 414
-
(1983)
Lancet
, vol.1
, pp. 414
-
-
Panayi, G.S.1
Huston, G.2
Shah, R.R.3
-
217
-
-
0027362069
-
Comparison of the pharmacokinetics of 1,2-dimethyl-3-hydroxypyrid-4-one (L1) in healty volunteers, with and without co-administration of ferrous sulfate, to thalassaemia patients
-
Stobie S, Tyberg J, Matsui D, et al. Comparison of the pharmacokinetics of 1,2-dimethyl-3-hydroxypyrid-4-one (L1) in healty volunteers, with and without co-administration of ferrous sulfate, to thalassaemia patients. Int J Clin Pharmacol Ther Toxicol 1993; 31: 602-5
-
(1993)
Int J Clin Pharmacol Ther Toxicol
, vol.31
, pp. 602-605
-
-
Stobie, S.1
Tyberg, J.2
Matsui, D.3
-
218
-
-
0027054371
-
Aluminium mobilisation in renal dialysis patients using the oral chelator 1,2-dimethyl-3-hydroxypyrid-4-one (L1)
-
Kontoghiorghes GJ, Barr J, Baillod RA. Aluminium mobilisation in renal dialysis patients using the oral chelator 1,2-dimethyl-3-hydroxypyrid-4-one (L1). Drugs Today (Barc) 1992; 28 Suppl. A: 183-7
-
(1992)
Drugs Today (Barc)
, vol.28
, Issue.SUPPL. A
, pp. 183-187
-
-
Kontoghiorghes, G.J.1
Barr, J.2
Baillod, R.A.3
-
219
-
-
0031922731
-
Assessment of the effect of the oral iron chelator deferiprone on asymptomatic Plasmodium falciparum parasitaemia in humans
-
Thuma PE, Olivieri NF, Mabeza GF, et al. Assessment of the effect of the oral iron chelator deferiprone on asymptomatic Plasmodium falciparum parasitaemia in humans. Am J Trop Med Hyg 1998; 58: 358-64
-
(1998)
Am J Trop Med Hyg
, vol.58
, pp. 358-364
-
-
Thuma, P.E.1
Olivieri, N.F.2
Mabeza, G.F.3
-
220
-
-
0022946184
-
In vitro screening of iron chelators using models of free radical damage
-
Kontoghiorghes GK, Jackson MI, Lunec J. In vitro screening of iron chelators using models of free radical damage. Free Radic Res Commun 1986; 2: 115-24
-
(1986)
Free Radic Res Commun
, vol.2
, pp. 115-124
-
-
Kontoghiorghes, G.K.1
Jackson, M.I.2
Lunec, J.3
-
221
-
-
0030091567
-
Role of iron in the potentiation of anthracycline cardiotoxicity: Identification of heart cell mitochondria as major site of iron-anthracycline interactions
-
Ling G, Tirosh R, Pinson A, et al. Role of iron in the potentiation of anthracycline cardiotoxicity: identification of heart cell mitochondria as major site of iron-anthracycline interactions. J Lab Clin Med 1996; 127: 272-8
-
(1996)
J Lab Clin Med
, vol.127
, pp. 272-278
-
-
Ling, G.1
Tirosh, R.2
Pinson, A.3
-
222
-
-
0023577562
-
Variation in iron accumulation, transferrin membrane binding and DNA synthesis in the K562 and U937 cell lines induced by chelators and their iron complexes
-
Forsbeck K, Nillson K, Kontoghiorghes GJ. Variation in iron accumulation, transferrin membrane binding and DNA synthesis in the K562 and U937 cell lines induced by chelators and their iron complexes. Eur J Haematol 1987; 39: 318-25
-
(1987)
Eur J Haematol
, vol.39
, pp. 318-325
-
-
Forsbeck, K.1
Nillson, K.2
Kontoghiorghes, G.J.3
-
223
-
-
0028219018
-
Iron-chelating agents in non-iron overload conditions
-
Voest EE, Vreugdenhil G, Marx JJM. Iron-chelating agents in non-iron overload conditions. Ann Intern Med 1994; 120: 490-9
-
(1994)
Ann Intern Med
, vol.120
, pp. 490-499
-
-
Voest, E.E.1
Vreugdenhil, G.2
Marx, J.J.M.3
-
224
-
-
0028321696
-
The oral iron chelator 1,2-dimethyl-3-hydroxypyrid-4-one reduces hepatic-free iron, lipid peroxidation and fat accumulation in chronically ethanol-fed rats
-
Sadrzadeh SMH, Nanji AA, Price PL. The oral iron chelator 1,2-dimethyl-3-hydroxypyrid-4-one reduces hepatic-free iron, lipid peroxidation and fat accumulation in chronically ethanol-fed rats. J Pharmacol Exp Ther 1994; 269: 632-6
-
(1994)
J Pharmacol Exp Ther
, vol.269
, pp. 632-636
-
-
Sadrzadeh, S.M.H.1
Nanji, A.A.2
Price, P.L.3
-
225
-
-
0030005823
-
The pharmacokinetics and blood-brain barrier permeation of the chelators 1,2-dimethyl, 1,2-diethyl, and 1-[ethan-l'ol]-2-methyl-3-hydroxypyrid-4-one in the rat
-
Fredenburg AM, Sethi RK, Allen DD, et al. The pharmacokinetics and blood-brain barrier permeation of the chelators 1,2-dimethyl, 1,2-diethyl, and 1-[ethan-l'ol]-2-methyl-3-hydroxypyrid-4-one in the rat. Toxicology 1996; 108 (3): 191-9
-
(1996)
Toxicology
, vol.108
, Issue.3
, pp. 191-199
-
-
Fredenburg, A.M.1
Sethi, R.K.2
Allen, D.D.3
-
226
-
-
0025580092
-
Uptake and intracellular distribution of iron from transferrin and chelators in erythroid cells
-
Kontoghiorghes GJ, May A. Uptake and intracellular distribution of iron from transferrin and chelators in erythroid cells. Biol Met 1990; 3: 183-7
-
(1990)
Biol Met
, vol.3
, pp. 183-187
-
-
Kontoghiorghes, G.J.1
May, A.2
-
227
-
-
0002614944
-
Stabilities of the iron (III) chelates of 1,2-dimethyl-3-hydroxy-4-pyridinone and related ligands
-
Motekaitis R. J, Martell AE. Stabilities of the iron (III) chelates of 1,2-dimethyl-3-hydroxy-4-pyridinone and related ligands. Inorg Chim Acta 1991; 183: 71-80
-
(1991)
Inorg Chim Acta
, vol.183
, pp. 71-80
-
-
Motekaitis, R.J.1
Martell, A.E.2
-
228
-
-
0030830275
-
Evaluation of a new method of administration of the iron chelating agent deferoxamine
-
Borgna-Pignatti C, Cohen A. Evaluation of a new method of administration of the iron chelating agent deferoxamine. J Pediatr 1997; 130: 86-8
-
(1997)
J Pediatr
, vol.130
, pp. 86-88
-
-
Borgna-Pignatti, C.1
Cohen, A.2
-
229
-
-
0026655514
-
Anemia and neutropenia in a case of copper deficiency: Role of copper in normal hematopoiesis
-
Hirase N, Abe Y, Salamura S, et al. Anemia and neutropenia in a case of copper deficiency: role of copper in normal hematopoiesis. Acta Haematol 1992; 87: 195-7
-
(1992)
Acta Haematol
, vol.87
, pp. 195-197
-
-
Hirase, N.1
Abe, Y.2
Salamura, S.3
-
230
-
-
0026016202
-
Anti-neutrophil antibodies in patients with nutritional copper deficiency
-
Higuchi S, Higashi A, Nahamura T, et al. Anti-neutrophil antibodies in patients with nutritional copper deficiency. Eur J Paediatr 1991; 150: 327-30
-
(1991)
Eur J Paediatr
, vol.150
, pp. 327-330
-
-
Higuchi, S.1
Higashi, A.2
Nahamura, T.3
-
232
-
-
0024399182
-
Idiosyncratic drug reaction: Possible role of reactive metabolites generated by leukocytes
-
Uetrecht JP. Idiosyncratic drug reaction: possible role of reactive metabolites generated by leukocytes. Pharm Res 1989; 6: 265-73
-
(1989)
Pharm Res
, vol.6
, pp. 265-273
-
-
Uetrecht, J.P.1
-
233
-
-
0038593465
-
L1NA11. -Altyl-2-methyl-3-hydroxypyrid-4-one
-
Kontoghiorghes GJ. L1NA11. -Altyl-2-methyl-3-hydroxypyrid-4-one. Drugs Future 1990; 15: 230-2
-
(1990)
Drugs Future
, vol.15
, pp. 230-232
-
-
Kontoghiorghes, G.J.1
-
234
-
-
0027053965
-
Effect on iron excretion and animal toxicology of L1 and other alpha-ketohydroxypyridine chelators
-
Nortey P, Barr J, Matsakis M, et al. Effect on iron excretion and animal toxicology of L1 and other alpha-ketohydroxypyridine chelators. Drugs Today (Barc) 1992; 28 Suppl. A: 81-8
-
(1992)
Drugs Today (Barc)
, vol.28
, Issue.SUPPL. A
, pp. 81-88
-
-
Nortey, P.1
Barr, J.2
Matsakis, M.3
-
235
-
-
0025134093
-
Development of an HPLC analytical method for orally administered 1-substituted-2-alkyl-3-hydroxypyrid-4-one iron chelators in biological fluids
-
Goddard JG, Kontoghiorghes GJ. Development of an HPLC analytical method for orally administered 1-substituted-2-alkyl-3-hydroxypyrid-4-one iron chelators in biological fluids. Clin Chem 1990; 36: 5-8
-
(1990)
Clin Chem
, vol.36
, pp. 5-8
-
-
Goddard, J.G.1
Kontoghiorghes, G.J.2
-
236
-
-
0038593466
-
Pharmacokinetics and whole body distribution of CP 502: A hydroxypyridinone second generation oral iron chelator
-
abstract book; 2002 Jul 4-7: Santorini Hellas
-
Spino M, Yang J. Pharmacokinetics and whole body distribution of CP 502: a hydroxypyridinone second generation oral iron chelator [abstract book]. 12th International Conference on Oral Chelation (ICOC); 2002 Jul 4-7: Santorini Hellas 2002, 83-4
-
(2002)
12th International Conference on Oral Chelation (ICOC)
, pp. 83-84
-
-
Spino, M.1
Yang, J.2
-
237
-
-
0037579288
-
ICL 670: Update on the clinical development of this new oral iron chelator
-
abstract book; 2002 Jul 4-7: Santorini, Hellas
-
Alberti A. ICL 670: update on the clinical development of this new oral iron chelator [abstract book]. 12th International Conference on Oral Chelation (ICOC); 2002 Jul 4-7: Santorini, Hellas 2002, 85-6
-
(2002)
12th International Conference on Oral Chelation (ICOC)
, pp. 85-86
-
-
Alberti, A.1
-
238
-
-
0038254839
-
Update on the effects of ICL 670, a novel tridentate oral iron chelator, on liver iron concentration in patients with transfusion dependent iron overload
-
abstract book; 2002 Jul 4-7: Santorini, Hellas
-
Galanello R, Cappellini MD, Piga A, et al. Update on the effects of ICL 670, a novel tridentate oral iron chelator, on liver iron concentration in patients with transfusion dependent iron overload [abstract book]. 12th International Conference on Oral Chelation (ICOC); 2002 Jul 4-7: Santorini, Hellas 2002, 90-1
-
(2002)
12th International Conference on Oral Chelation (ICOC)
, pp. 90-91
-
-
Galanello, R.1
Cappellini, M.D.2
Piga, A.3
-
239
-
-
0037917307
-
Bioavailability and pharmacokinetic properties of GT56-252, a novel orally available iron chelator
-
abstract book; 2002 Jul 4-7: Santorini, Hellas. (P1)
-
Marquis JK, Bree M, Appelqvist T. Bioavailability and pharmacokinetic properties of GT56-252, a novel orally available iron chelator [abstract book]. 12th International Conference on Oral Chelation (ICOC); 2002 Jul 4-7: Santorini, Hellas. 2002: 113 (P1)
-
(2002)
12th International Conference on Oral Chelation (ICOC)
, pp. 113
-
-
Marquis, J.K.1
Bree, M.2
Appelqvist, T.3
-
240
-
-
0037917307
-
Pharmaology and toxicology of GT56-252, a novel orally available iron chelator
-
abstract book; 2002 Jul 4-7: Santorini, Hellas, (P2)
-
Marquis JK, Aoude-Dagher R, Guillaumat PO. Pharmaology and toxicology of GT56-252, a novel orally available iron chelator [abstract book]. 12th International Conference on Oral Chelation (ICOC); 2002 Jul 4-7: Santorini, Hellas 2002, 113 (P2)
-
(2002)
12th International Conference on Oral Chelation (ICOC)
, pp. 113
-
-
Marquis, J.K.1
Aoude-Dagher, R.2
Guillaumat, P.O.3
-
241
-
-
45949113016
-
Simple synthesis of the potent iron chelators 1-alkyl-3-hydroxy-2-methylpyrid-4-ones
-
Kontoghiorghes GJ, Sheppard L. Simple synthesis of the potent iron chelators 1-alkyl-3-hydroxy-2-methylpyrid-4-ones. Inorg Chim Acta 1987; 136: L11-2
-
(1987)
Inorg Chim Acta
, vol.136
-
-
Kontoghiorghes, G.J.1
Sheppard, L.2
-
242
-
-
0026006236
-
Oral iron chelation is here
-
Kontoghiorghes GJ. Oral iron chelation is here. BMJ 1991; 303: 1279-80
-
(1991)
BMJ
, vol.303
, pp. 1279-1280
-
-
Kontoghiorghes, G.J.1
|