High cardiorespiratory fitness can reduce glycated hemoglobin levels regardless of polygenic risk for Type 2 diabetes mellitus in nondiabetic Japanese men

Physiological Genomics

Volumn 46, Issue 14, 2014, Pages 497-504

  Tanisawa, Kumpei ^a,b   Ito, Tomoko ^a   Sun, Xiaomin ^a   Ise, Ryuken ^a   Oshima, Satomi ^a   Cao, Zhen Bo ^a   Sakamoto, Shizuo ^a   Tanaka, Masashi ^b   Higuchi, Mitsuru ^a  

^a WASEDA UNIVERSITY   (Japan)

^b TOKYO METROPOLITAN INSTITUTE OF GERONTOLOGY   (Japan)

Author keywords

Cardiorespiratory fitness; HbA1c; Polygenic risk; cell function

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 2B; GLUCOSE; HEMOGLOBIN A1C; INSULIN; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR6.2; OXYGEN; POTASSIUM CHANNEL KCNQ1; TRANSCRIPTION FACTOR 7 LIKE 2; GLUCOSE BLOOD LEVEL; GLYCOSYLATED HEMOGLOBIN; HEMOGLOBIN A1C PROTEIN, HUMAN;

ADULT; AGED; ARTICLE; C2CD4A GENE; CARDIORESPIRATORY FITNESS; CARDIOVASCULAR FUNCTION; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; CYCLIN DEPENDENT KINASE 5 REGULATORY SUBUNIT ASSOCIATED PROTEIN 1 LIKE GENE; CYCLIN DEPENDENT KINASE INHIBITOR 2B GENE; FITNESS; GCKR GENE; GENE; GENETIC RISK; GENETIC RISK SCORE; GLUCOSE BLOOD LEVEL; GLUCOSE METABOLISM; HEMOGLOBIN BLOOD LEVEL; HHEX GENE; HUMAN; IGF2BP2 GEME; INSULIN RESISTANCE; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR6.2 GENE; JAPANESE (PEOPLE); MAJOR CLINICAL STUDY; MALE; MTNR1B GENE; NON INSULIN DEPENDENT DIABETES MELLITUS; OXYGEN CONSUMPTION; PANCREAS ISLET BETA CELL; PANCREAS ISLET CELL FUNCTION; POTASSIUM CHANNEL KCNQ1 GENE; PREDICTION; PRIORITY JOURNAL; REDUCTION; RESPIRATORY FUNCTION; SCORING SYSTEM; SINGLE NUCLEOTIDE POLYMORPHISM; SLC30A8 GENE; TRANSCRIPTION FACTOR 7 LIKE 2 GENE; ASIAN CONTINENTAL ANCESTRY GROUP; GENETICS; METABOLISM; MIDDLE AGED; RISK; RISK FACTOR; YOUNG ADULT;

ADULT; AGED; ASIAN CONTINENTAL ANCESTRY GROUP; BLOOD GLUCOSE; CROSS-SECTIONAL STUDIES; DIABETES MELLITUS, TYPE 2; GLUCOSE; HEMOGLOBIN A, GLYCOSYLATED; HUMANS; INSULIN; INSULIN RESISTANCE; INSULIN-SECRETING CELLS; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK; RISK FACTORS; YOUNG ADULT;

EID: 84904303217     PISSN: 10948341     EISSN: 15312267     Source Type: Journal    
DOI: 10.1152/physiolgenomics.00027.2014     Document Type: Article

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