Genotype risk score of common susceptible variants for prediction of type 2 diabetes mellitus in Japanese: The Shimanami Health Promoting Program (J-SHIPP study): Development of type 2 diabetes mellitus and genotype risk score

Metabolism: Clinical and Experimental

Volumn 60, Issue 11, 2011, Pages 1634-1640

  Tabara, Yasuharu ^a,b   Osawa, Haruhiko ^a,b   Kawamoto, Ryuichi ^a,b   Onuma, Hiroshi ^a,b   Shimizu, Ikki ^c   Makino, Hideichi ^a   Kohara, Katsuhiko ^a,b   Miki, Tetsuro ^a,b  

^a EHIME UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b EHIME UNIVERSITY   (Japan)

^c Ehime Prefectural Hospital   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CDKAL1 PROTEIN; CYCLIN DEPENDENT KINASE INHIBITOR; CYCLIN DEPENDENT KINASE INHIBITOR 2AB; GCKR PROTEIN; GLUCOSE; HHEX PROTEIN; IGF2BP2 PROTEIN; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR6.2; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; POTASSIUM CHANNEL KCNQ1; PROTEIN; TRANSCRIPTION FACTOR 7 LIKE 2; UNCLASSIFIED DRUG;

ADULT; AGED; ALLELE; ARTICLE; BODY MASS; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DISEASE PREDISPOSITION; FEMALE; FOLLOW UP; GENETIC ASSOCIATION; GENETIC EPIDEMIOLOGY; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOTYPE; GENOTYPE RISK; GLUCOSE BLOOD LEVEL; HUMAN; JAPANESE; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD REVIEW; NON INSULIN DEPENDENT DIABETES MELLITUS; PRIORITY JOURNAL; PROGNOSIS; RISK ASSESSMENT; SCORING SYSTEM; SINGLE NUCLEOTIDE POLYMORPHISM;

AGED; AGED, 80 AND OVER; ASIAN CONTINENTAL ANCESTRY GROUP; CROSS-SECTIONAL STUDIES; DIABETES MELLITUS, TYPE 2; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HEALTH PROMOTION; HUMANS; JAPAN; MALE; MIDDLE AGED; NATIONAL HEALTH PROGRAMS; POLYMORPHISM, SINGLE NUCLEOTIDE; PROGNOSIS; RESEARCH DESIGN; RISK FACTORS;

EID: 80054979509     PISSN: 00260495     EISSN: 15328600     Source Type: Journal    
DOI: 10.1016/j.metabol.2011.03.014     Document Type: Article

References (30)

1. B.F. Voight, L.J. Scott, and V. Steinthorsdottir Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis Nat Genet 42 2010 579 589
2. Y. Horikawa, K. Miyake, and K. Yasuda Replication of genome-wide association studies of type 2 diabetes susceptibility in Japan J Clin Endocrinol Metab 93 2008 3136 3141
3. S. Omori, Y. Tanaka, and A. Takahashi Association of CDKAL1, IGF2BP2, CDKN2A/B, HHEX, SLC30A8, and KCNJ11 with susceptibility to type 2 diabetes in a Japanese population Diabetes 57 2008 791 795
4. M.C. Ng, K.S. Park, and B. Oh Implication of genetic variants near TCF7L2, SLC30A8, HHEX, CDKAL1, CDKN2A/B, IGF2BP2, and FTO in type 2 diabetes and obesity in 6,719 Asians Diabetes 57 2008 2226 2233
5. M. Chidambaram, V. Radha, and V. Mohan Replication of recently described type 2 diabetes gene variants in a South Indian population Metabolism 59 2010 1760 1766
6. V. Legry, D. Cottel, and J. Ferrières Effect of an FTO polymorphism on fat mass, obesity, and type 2 diabetes mellitus in the French MONICA Study Metabolism 58 2009 971 975
7. D. Bodhini, V. Radha, and M. Dhar The rs12255372(G/T) and rs7903146(C/T) polymorphisms of the TCF7L2 gene are associated with type 2 diabetes mellitus in Asian Indians Metabolism 56 2007 1174 1178
8. Y. Tabara, H. Osawa, and R. Kawamoto Replication study of candidate genes associated with type 2 diabetes based on genome-wide screening Diabetes 58 2009 493 498
9. V. Lyssenko, A. Jonsson, and P. Almgren Clinical risk factors, DNA variants, and the development of type 2 diabetes N Engl J Med 359 2008 2220 2232
10. J.B. Meigs, P. Shrader, and L.M. Sullivan Genotype score in addition to common risk factors for prediction of type 2 diabetes N Engl J Med 359 2008 2208 2219
11. V. Lyssenko, P. Almgren, and D. Anevski Genetic prediction of future type 2 diabetes PLoS Med 2 2005 e345
12. M. Vaxillaire, J. Veslot, and C. Dina Impact of common type 2 diabetes risk polymorphisms in the DESIR prospective study Diabetes 57 2008 244 254
13. M.C. Cornelis, L. Qi, and C. Zhang Joint effects of common genetic variants on the risk for type 2 diabetes in U.S. men and women of European ancestry Ann Intern Med 150 2009 541 550
14. T. Sparsø, A. Bonnefond, and E. Andersson G-allele of intronic rs10830963 in MTNR1B confers increased risk of impaired fasting glycemia and type 2 diabetes through an impaired glucose-stimulated insulin release: studies involving 19,605 Europeans Diabetes 58 2009 1450 1456
15. N. Grarup, G. Andersen, and N.T. Krarup Association testing of novel type 2 diabetes risk alleles in the JAZF1, CDC123/CAMK1D, TSPAN8, THADA, ADAMTS9, and NOTCH2 loci with insulin release, insulin sensitivity, and obesity in a population-based sample of 4,516 glucose-tolerant middle-aged Danes Diabetes 57 2008 2534 2540
16. A. Bonnefond, M. Vaxillaire, and Y. Labrune Genetic variant in HK1 is associated with a proanemic state and A1C but not other glycemic control-related traits Diabetes 58 2009 2687 2697
17. C. Sabatti, S.K. Service, and A.L. Hartikainen Genome-wide association analysis of metabolic traits in a birth cohort from a founder population Nat Genet 41 2009 35 46
18. M.S. Sandhu, M.N. Weedon, and K.A. Fawcett Common variants in WFS1 confer risk of type 2 diabetes Nat Genet 39 2007 951 953
19. W. Winckler, M.N. Weedon, and R.R. Graham Evaluation of common variants in the six known maturity-onset diabetes of the young (MODY) genes for association with type 2 diabetes Diabetes 56 2007 685 693
20. D.K. Sanghera, F.Y. Demirci, and L. Been PPARG and ADIPOQ gene polymorphisms increase type 2 diabetes mellitus risk in Asian Indian Sikhs: Pro12Ala still remains as the strongest predictor Metabolism 59 2010 492 501
21. K.S. Vimaleswaran, V. Radha, and M.G. Jayapriya Evidence for an association with type 2 diabetes mellitus at the PPARG locus in a South Indian population Metabolism 59 2010 457 462
22. K. Yasuda, K. Miyake, and Y. Horikawa Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus Nat Genet 40 2008 1092 1097
23. H. Osawa, K. Yamada, and H. Onuma The G/G genotype of a resistin single-nucleotide polymorphism at -420 increases type 2 diabetes mellitus susceptibility by inducing promoter activity through specific binding of Sp1/3 Am J Hum Genet 75 2004 678 686
24. H. Mori, H. Ikegami, and Y. Kawaguchi The Pro12 ->Ala substitution in PPAR-gamma is associated with resistance to development of diabetes in the general population: possible involvement in impairment of insulin secretion in individuals with type 2 diabetes Diabetes 50 2001 891 894
25. H. Onum, Y. Tabara, and R. Kawamoto, The GCKR rs780094 polymorphism is associated with susceptibility of type 2 diabetes, reduced fasting plasma glucose levels, increased triglycerides levels, and lower HOMA-IR in Japanese population J Hum Genet 55 2010 600 604
26. F. Takeuchi, T. Katsuya, and S. Chakrewarthy Common variants at the GCK, GCKR, G6PC2-ABCB11 and MTNR1B loci are associated with fasting glucose in two Asian populations Diabetologia 53 2010 299 308
27. K. Hara, T. Okada, and K. Tobe The Pro12Ala polymorphism in PPAR gamma2 may confer resistance to type 2 diabetes Biochem Biophys Res Commun 271 2000 212 216
28. C.C. Jensen, M. Cnop, and R.L. Hull Beta-cell function is a major contributor to oral glucose tolerance in high-risk relatives of four ethnic groups in the U.S Diabetes 51 2002 2170 2178
29. M. Fukushima, H. Suzuki, and Y. Seino Insulin secretion capacity in the development from normal glucose tolerance to type 2 diabetes Diabetes Res Clin Pract 66 2004 S37 S43
30. A. Stancáková, T. Kuulasmaa, and J. Paananen Association of 18 confirmed susceptibility loci for type 2 diabetes with indices of insulin release, proinsulin conversion, and insulin sensitivity in 5,327 nondiabetic Finnish men Diabetes 58 2009 2129 2136