Protective effect of Selenium nanoparticle against Cyclophosphamide induced hepatotoxicity and genotoxicity in Swiss albino mice

Journal of Biomaterials Applications

Volumn 29, Issue 2, 2014, Pages 303-317

  Bhattacharjee, Arin ^a   Basu, Abhishek ^a   Ghosh, Prosenjit ^a   Biswas, Jaydip ^a   Bhattacharya, Sudin ^a  

^a CHITTARANJAN NATIONAL CANCER INSTITUTE   (India)

Author keywords

antioxidant enzyme; cyclophosphamide; genotoxicity; hepatotoxicity; Nano Se; oxidative stress

Indexed keywords

AMINO ACIDS; ANTIOXIDANTS; BONE; CHROMOSOMES; ENZYME ACTIVITY; MAMMALS; OXIDATIVE STRESS; OXYGEN; PEPTIDES; PLANTS (BOTANY); SELENIUM;

ANTIOXIDANT ENZYME; CYCLOPHOSPHAMIDE; GENOTOXICITIES; HEPATOTOXICITY; NANO-SE;

SELENIUM COMPOUNDS;

ALANINE AMINOTRANSFERASE; CYCLOPHOSPHAMIDE; ENZYME; GLUTATHIONE; MALONALDEHYDE; NANOPARTICLE; REACTIVE OXYGEN METABOLITE; SELENIUM; TRACE ELEMENT;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BONE MARROW; CANCER CHEMOTHERAPY; CHROMOSOME ABERRATION; CONTROLLED STUDY; DNA DAMAGE; ENZYME ACTIVITY; FEMALE; GENOTOXICITY; LIVER INJURY; LIVER TOXICITY; LYMPHOCYTE; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 84904298677     PISSN: 08853282     EISSN: 15308022     Source Type: Journal    
DOI: 10.1177/0885328214523323     Document Type: Article

References (59)

1. Sarkar FH, Li Y. Using chemopreventive agents to enhance the efficacy of cancer therapy. Cancer Res. 2006 ; 66: 3347-3350
2. Fraiser LH, Kanekal S, Kehrer JP. Cyclophosphamide toxicity. Drugs. 1991 ; 42: 781-795
3. Gokhale AB, Damre AS, Saraf MN. Investigations into the immunomodulatory activity of Argyreia speciosa. J Ethnopharmacol. 2003 ; 84: 109-114 (Pubitemid 36034243)
4. Wang X, Zhang J, Xu T. Cyclophosphamide as a potent inhibitor of tumor thioredoxin reductase in vivo. Toxicol Appl Pharmacol. 2007 ; 218: 88-95 (Pubitemid 46026846)
5. Ponticelli C, Passerini P. Alkylating agents and purine analogues in primary glomerulonephritis with nephrotic syndrome. Nephrol Dial Transplant. 1991 ; 6: 381-388
6. Eisler R Selenium handbook of chemical risk assessment: health hazards to humans plants and animals. Boca Raton, FL: Lewis Publishers ; 2000: 1649-1705.
7. Klasing KC Comparative avian nutrition. New York: Oxford University Press ; 1998 :
8. Rotruck JT, Pope AL, Ganther HE. Selenium: biochemical role as a component of glutathione peroxidase. Science. 1973 ; 179: 585-590
9. Whanger PD. Selenium and its relationship to cancer: an update dagger. Br J Nutr. 2004 ; 91: 11-28 (Pubitemid 38100556)
10. Sugie S, Tanaka T, El-Bayoumy K. Chemoprevention of carcinogenesis by organoselenium compounds. J Health Sci. 2000 ; 46: 422-425 (Pubitemid 32016281)
11. Ip C. Lessons from basic research in selenium and cancer prevention. J Nutr. 1998 ; 128: 1845-1854 (Pubitemid 28509845)
12. Narajji C, Karvekar MD, Das AK. Biological importance of organoselenium compounds. Ind J Pharm Sci. 2007 ; 69: 344-351 (Pubitemid 47379260)
13. Muller A, Cadenas E, Graf P, et al. A novel biologically active seleno-organic compound-I Glutathione peroxidase-like activity in vitro and antioxidant capacity of PZ 51 (Ebselen). Biochem Pharmacol. 1984 ; 33: 3235-3239 (Pubitemid 14023257)
14. Zhang J, Wang X, Xu T. Elemental selenium at nano size (Nano-Se) as a potential chemopreventive agent with reduced risk of selenium toxicity: comparison with se-methylselenocysteine in mice. Toxicol Sci. 2008 ; 101: 22-31 (Pubitemid 350239009)
15. Wang H, Zhang J, Yu H. Elemental selenium at nano size possesses lower toxicity without compromising the fundamental effect on selenoenzymes: comparison with selenomethionine in mice. Free Radic Biol Med. 2007 ; 42: 1524-1533 (Pubitemid 46590615)
16. Zhang J, Wang H, Bao Y, et al. Nano red elemental selenium has no size effect in the induction of seleno-enzymes in both cultured cells and mice. Life Sci. 2004 ; 75: 237-244 (Pubitemid 38553878)
17. Peng D, Zhang J, Liu Q, et al. Size effect of elemental selenium nano particles (Nano-Se) at supranutritional levels on selenium accumulation and glutathione S-transferase activity. J Inorg Biochem. 2007 ; 101: 1457-1463 (Pubitemid 47362368)
18. Huang B, Zhang J, Hou J, et al. Free radical scavenging efficiency of Nano-Se in vitro. Free Radic Biol Med. 2003 ; 35: 805-813 (Pubitemid 37329484)
19. Lu J, Wu DM, Hu B, et al. Chronic administration of troxerutin protects mouse brain against D-galactose induced impairment of cholinergic system. Neurobiol Learn Mem. 2010 ; 93: 157-164
20. Shinomol GK, Muralidhara. Differential induction of oxidative impairments in brain regions of male mice following sub chronic consumption of Khesari dhal (Lathyrus sativus) and detoxified Khesari dhal. Neurotoxicology. 2007 ; 28: 798-806 (Pubitemid 47058572)
21. Okhawa H, Ohishi N, Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Annal Biochem. 1979 ; 95: 351-358 (Pubitemid 9194347)
22. Bergmeyer HU, Scheibe P, Wahlefeld AW. Optimization of methods for aspartate aminotransferase and alanine aminotransferase. Clin Chem. 1978 ; 24: 58-61
23. Sedlack J, Lindsay RN. Estimation of total protein bound and non-protein sulfhydryl groups in tissue with ellman's reagent. Annal Biochem. 1968 ; 25: 192-205
24. Habig WH, Pabst MJ, Jacoby WB. Glutathione S-transferases, the first enzymatic step in marcapturic acid formation. J Biol Chem. 1974 ; 249: 7130-7139
25. Paglia DE, Valentine WN. Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase. J Lab Clin Med. 1967 ; 70: 158-169
26. Marklund S, Marklund G. Involvement of the superoxide anion radical in autooxidation of pyrogallol and a convenient assay for superoxide dismutase. Eur J Biochem. 1974 ; 47: 469-474
27. McCord JM, sand Fridovich I. Superoxide dismutase: an enzymatic function for erythrocuprein (hemoprotein). J Biol Chem. 1969 ; 244: 6049-6055
28. Luck HA Methods of enzymatic analysis. Bergmeyer HV, ed. New York, NY: Academic Press ; 1963: 886-888.
29. Wintrobe MM Clinical hematology. 7 th edn. Philadelphia: Lea & Febiger, 1975, pp. 114-115. Philadelphia: Lea & Febiger ; 1975: 114-115.
30. Lowry OH, Rosenbrough NJ, Farr AL, et al. Protein measurement with the folin phenol reagent. J Biol Chem. 1951 ; 193: 265-276
31. Endoh D, Okui T, Ozawa S, et al. Protective effect of a lignan-containing flaxseed extract against CCl4-induced hepatic injury. J Vet Med Sci. 2002 ; 64: 761-765
32. Singh NP, McCoy MT, Tice RR, et al. A simple technique for quantitation of low levels of DNA damage in individual cells. Exp Cell Res. 1988 ; 175: 184-191
33. Tice RR, Agurell E, Anderson D, et al. Single cell gel/comet assay: guidelines for in vitro and in vivo genetic toxicology testing. Environ Mol Mutagen. 2000 ; 35: 206-221 (Pubitemid 30196665)
34. Huang W, Xing W, Li D, et al. Microcystin-RR induced apoptosis in tobacco BY-2 suspension cells is mediated by reactive oxygen species and mitochondrial permeability transition pore status. Toxicol in Vitro. 2008 ; 22: 328-337
35. Biswas SJ, Pathak S, Khuda Bukhsh AR. Assessment of the genotoxic and cytotoxic potential of an antiepileptic drug Phenobarbital, in mice: a time course study. Mutat Res. 2004 ; 563: 1-11 (Pubitemid 39504754)
36. Matés JM. Antioxidant enzymes and human diseases. Clin Biochem. 1999 ; 32: 595-603 (Pubitemid 30039087)
37. Hassan W, Ibrahim M, Nogueira CW, et al. Effects of acidosis and Fe (II) on lipid peroxidation in phospholipid extract: Comparative effect of diphenyl diselenide and ebselen. Environ Toxicol Pharmacol. 2009 ; 28: 152-154
38. Talas ZS, Ozdemir I, Ates B, et al. Modulating effects of selenium in adrenal medulla of rats exposed to 7,12-dimethylbenz[a]anthracene. Toxicol Ind Health. 2013 ; 29: 286-292
39. Ungvári E, Monori I, Megyeri A, et al. Protective effects of meat from lambs on selenium nanoparticle supplemented diet in a mouse model of polycyclic aromatic hydrocarbon-induced immunotoxicity. Food Chem Toxicol. 2013 ; 64C: 298-306
40. Cathcart R, Schwiers E, Ames BN. Detection of picomole levels of hydroperoxides using a fluorescent dichlorofluorescein assay. Anal Biochem. 1983 ; 134: 111-116 (Pubitemid 14231364)
41. Crow JP. Dichlorodihydrofluorescein and dihydrorhodamine 123 are sensitive indicators of peroxynitrite in vitro: implications for intracellular measurement of reactive nitrogen and oxygen species. Nitric Oxide. 1997 ; 1: 145-157 (Pubitemid 28076555)
42. Dumontet C, Drai J, Thieblemont C, et al. The superoxide dismutase content in erythrocytes predicts short-term toxicity of high-dose cyclophosphamide. Br J Haematol. 2001 ; 112: 405-409 (Pubitemid 32183487)
43. Halliwell B, Gutteridge JM Free radicals in biology and medicine. 2 nd edn. Oxford: Clarendon Press, 1989, pp. 1-20. Oxford: Clarendon Press ; 1989: 1-20.
44. El-Demerdash FM. Antioxidant effect of vitamin E and selenium on lipid peroxidation, enzyme activities and biochemical parameters in rats exposed to aluminium. J Trace Elem Med Biol. 2004 ; 18: 113-121 (Pubitemid 39285971)
45. Yousefipour Z, Ranganna K, Newaz MA, et al. Mechanism of acrolein-induced vascular toxicity. J Physiol Pharmacol. 2005 ; 56: 337-353 (Pubitemid 41406469)
46. Srivastava A, Shivanandappa T. Hepatoprotective effect of the root extract of Decalepis hamiltonii against carbon tetrachloride-induced oxidative stress in rats. Food Chem. 2010 ; 118: 411-417
47. Dirven HA, van Ommen B, van Bladeren PJ. Involvement of human glutathione-S-transferase isoenzymes in the conjugation of cyclophosphamide metabolites with glutathione. Cancer Res. 1994 ; 54: 6215-6220 (Pubitemid 24378656)
48. Tappel AL. Glutathione peroxidase and hydroperoxides. Methods Enzymol. 1978 ; 52: 506-513
49. Talas ZS, Ozdemir I, Gok Y, et al. Role of selenium compounds on tyrosine hydroxylase activity, adrenomedullin and total RNA levels in hearts of rats. Regul Pept. 2010 ; 159: 137-141
50. Sigalov AB, Stern LJ. Enzymatic repair of oxidative damage to human apolipoprotein A-I. FEBS Lett. 1998 ; 433: 196-200 (Pubitemid 128369960)
51. Vo TK, Druez C, Delzenne N, et al. Analysis of antioxidant defense systems during rat hepatocarcinogenesis. Carcinogenesis. 1988 ; 9: 2009-2013
52. Rajasekaran NS, Devaraj H, Devaraj SN. The effect of glutathione monoester (GME) on glutathione (GSH) depleted rat liver. J Nutr Biochem. 2002 ; 13: 302-306 (Pubitemid 34556692)
53. Groopman JE, Itri LM. Chemotherapy-induced anemia in adults: incidence and treatment. J Natl Cancer Inst. 1999 ; 91: 1616-1634 (Pubitemid 29479929)
54. Vrzoc M, Petras ML. Comparison of alkaline single cell gel comet and peripheral blood micronucleus assays in detecting DNA damage caused by direct and indirect acting mutagens. Mutat Res. 1997 ; 381: 31-40 (Pubitemid 27504564)
55. Matalon ST, Orney A, Lishner M. Review of the potential effects of three commonly used antineoplastic and immunosuppressive drugs (cyclophosphamide, azathioprine, doxorubicinon the embryo and placenta). Reprod Toxicol. 2004 ; 18: 219-230 (Pubitemid 38333046)
56. Kussmaul AR, Bogacheva MA, Shkurat TP, et al. Inhibitory effect of apigenin on benzo(a)pyrene-mediated genotoxicity in Swiss albino mice. J Pharm Pharmacol. 2006 ; 58: 1655-1660
57. Vijayalakshmi P, Geetha CS, Mohanan PV. Assessment of oxidative stress and chromosomal aberration inducing potential of three medical grade silicone polymer materials. J Biomater Appl. 2013 ; 27: 763-772
58. Jenderny J, Walk RA, Hackenberg U, et al. Chromosomal abnormalities and sister-chromatid exchange in bone marrow cells of mice and Chinese hamsters after inhalation and intraperitoneal administration. II. Cyclophosphamide. Mutat Res. 1988 ; 203: 1-10 (Pubitemid 18036815)
59. Moore FR, Urda GA, Krishna G, et al. An in vivo/in vitro method for assessing micronucleus and chromosome aberration induction in rat bone marrow and spleen. 1. Studies with cyclophosphamide. Mutat Res. 1995 ; 335: 191-199