Overexpression of a non-native deoxyxylulose-dependent vitamin B6 pathway in Bacillus subtilis for the production of pyridoxine

Metabolic Engineering

Volumn 25, Issue , 2014, Pages 38-49

  Commichau, Fabian M ^a,b   Alzinger, Ariane ^a   Sande, Rafael ^a   Bretzel, Werner ^a   Meyer, Frederik M ^a   Chevreux, Bastien ^a   Wyss, Markus ^a   Hohmann, Hans Peter ^a   Prágai, Zoltán ^a  

^a DSM NUTRITIONAL PRODUCTS LTD   (Switzerland)

^b UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

Antimetabolite; Bacillus subtilis; Heterologous gene expression; Pyridoxine; Vitamin B6

Indexed keywords

AMINO ACIDS; ASSAYS; COENZYMES; ESCHERICHIA COLI; FERMENTATION; GENE EXPRESSION;

ANTIMETABOLITE; BACILLUS SUBTILIS; HETEROLOGOUS GENE EXPRESSIONS; PYRIDOXINE; VITAMIN B-6;

BIOSYNTHESIS;

CASAMINO ACID; CHLORAMPHENICOL; ISOPRENOID; PHOSPHATE; PYRIDOXINE; SPECTINOMYCIN; THIAMINE; XYLULOSE; 1-DEOXY-2-PENTULOSE;

ARTICLE; AUXOTROPHY; BACILLUS SUBTILIS; BACTERIAL CHROMOSOME; BACTERIAL GENE; BACTERIAL GENOME; BACTERIAL STRAIN; BIOLOGICAL ACTIVITY; BIOSYNTHESIS; CARBON SOURCE; CONTROLLED STUDY; CYTOLYSIS; ESCHERICHIA COLI; FERMENTATION; GEL ELECTROPHORESIS; GENE OVEREXPRESSION; GENETIC STABILITY; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATION; PLASMID; PRIORITY JOURNAL; PRODUCTIVITY; SINORHIZOBIUM MELILOTI; SUPERNATANT; SUPPLEMENTATION; WILD TYPE; ANALOGS AND DERIVATIVES; CELL PROLIFERATION; GENETIC ENHANCEMENT; GENETICS; METABOLIC ENGINEERING; METABOLISM; PHYSIOLOGY; PROCEDURES; SIGNAL TRANSDUCTION; UPREGULATION;

BACILLUS SUBTILIS; CELL PROLIFERATION; GENETIC ENHANCEMENT; METABOLIC ENGINEERING; PYRIDOXINE; SIGNAL TRANSDUCTION; UP-REGULATION; VITAMIN B 6; XYLULOSE;

EID: 84904280695     PISSN: 10967176     EISSN: 10967184     Source Type: Journal    
DOI: 10.1016/j.ymben.2014.06.007     Document Type: Article

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