-
1
-
-
17044387386
-
Hsp70 chaperones: Cellular functions and molecular mechanism
-
Mayer MP, Bukau B (2005) Hsp70 chaperones: Cellular functions and molecular mechanism. Cell Mol Life Sci 62:670-684.
-
(2005)
Cell Mol Life Sci
, vol.62
, pp. 670-684
-
-
Mayer, M.P.1
Bukau, B.2
-
2
-
-
34447528828
-
The heat-Shock protein 70 family: Highly homologous proteins with overlapping and distinct functions
-
Daugaard MM, Rohde MM, Jäättel̈a MM (2007) The heat-Shock protein 70 family: Highly homologous proteins with overlapping and distinct functions. FEBS Lett 581:3702-3710.
-
(2007)
FEBS Lett
, vol.581
, pp. 3702-3710
-
-
Daugaard, M.M.1
Rohde, M.M.2
Jäättel̈a, M.M.3
-
3
-
-
0027414085
-
Identification of a novel member of mouse hsp70 family. Its association with cellular mortal phenotype
-
Wadhwa R, Kaul SC, Ikawa Y, Sugimoto Y (1993) Identification of a novel member of mouse hsp70 family. Its association with cellular mortal phenotype. J Biol Chem 268:6615-6621.
-
(1993)
J Biol Chem
, vol.268
, pp. 6615-6621
-
-
Wadhwa, R.1
Kaul, S.C.2
Ikawa, Y.3
Sugimoto, Y.4
-
4
-
-
0024380865
-
Identification, characterization, and purification of two mammalian stress proteins present in mitochondria, grp 75, a member of the hsp 70 family and hsp 58, a homolog of the bacterial groEL protein
-
Mizzen LA, Chang C, Garrels JI, Welch WJ (1989) Identification, characterization, and purification of two mammalian stress proteins present in mitochondria, grp 75, a member of the hsp 70 family and hsp 58, a homolog of the bacterial groEL protein. J Biol Chem 264:20664-20675.
-
(1989)
J Biol Chem
, vol.264
, pp. 20664-20675
-
-
Mizzen, L.A.1
Chang, C.2
Garrels, J.I.3
Welch, W.J.4
-
5
-
-
33847651284
-
Three faces of mortalin: A housekeeper, guardian and killer
-
Kaul SC, Deocaris CC, Wadhwa R (2007) Three faces of mortalin: A housekeeper, guardian and killer. Exp Gerontol 42:263-274.
-
(2007)
Exp Gerontol
, vol.42
, pp. 263-274
-
-
Kaul, S.C.1
Deocaris, C.C.2
Wadhwa, R.3
-
6
-
-
33747170368
-
Evolution of mitochondrial chaperones utilized in Fe-S cluster biogenesis
-
Schilke B, Williams B, Knieszner H, Pukszta S, D'Silva P, Craig EA, Marszalek J (2006) Evolution of mitochondrial chaperones utilized in Fe-S cluster biogenesis. Curr Biol 16:1660-1665.
-
(2006)
Curr Biol
, vol.16
, pp. 1660-1665
-
-
Schilke, B.1
Williams, B.2
Knieszner, H.3
Pukszta, S.4
D'Silva, P.5
Craig, E.A.6
Marszalek, J.7
-
7
-
-
0028132179
-
Mitochondrial Hsp70/MIM44 complex facilitates protein import
-
Schneider HC, Berthold J, Bauer MF, Dietmeier K, Guiard B, Brunner M, Neupert W (1994) Mitochondrial Hsp70/MIM44 complex facilitates protein import. Nature 371:768-774.
-
(1994)
Nature
, vol.371
, pp. 768-774
-
-
Schneider, H.C.1
Berthold, J.2
Bauer, M.F.3
Dietmeier, K.4
Guiard, B.5
Brunner, M.6
Neupert, W.7
-
8
-
-
0037418880
-
Regulated cycling of mitochondrial Hsp70 at the protein import channel
-
Liu Q, D'Silva P, Walter W, Marszalek J, Craig EA (2003) Regulated cycling of mitochondrial Hsp70 at the protein import channel. Science 300:139-141.
-
(2003)
Science
, vol.300
, pp. 139-141
-
-
Liu, Q.1
D'Silva, P.2
Walter, W.3
Marszalek, J.4
Craig, E.A.5
-
9
-
-
0036257364
-
Voltage-Dependent anionselective channel (VDAC) interacts with the dynein light chain Tctex1 and the heat-Shock protein PBP74
-
Schwarzer C, Barnikol-Watanabe S, Thinnes FP, Hilschmann N (2002) Voltage-Dependent anionselective channel (VDAC) interacts with the dynein light chain Tctex1 and the heat-Shock protein PBP74. Int J Biochem Cell Biol 34:1059-1070.
-
(2002)
Int J Biochem Cell Biol
, vol.34
, pp. 1059-1070
-
-
Schwarzer, C.1
Barnikol-Watanabe, S.2
Thinnes, F.P.3
Hilschmann, N.4
-
10
-
-
14244268253
-
Effect of GRP75/ mthsp70/PBP74/mortalin overexpression on intracellular ATP level, mitochondrial membrane potential and ROS accumulation following glucose deprivation in PC12 cells
-
Liu Y, Liu W, Song X-D, Zuo J (2005) Effect of GRP75/ mthsp70/PBP74/mortalin overexpression on intracellular ATP level, mitochondrial membrane potential and ROS accumulation following glucose deprivation in PC12 cells. Mol Cell Biochem 268:45-51.
-
(2005)
Mol Cell Biochem
, vol.268
, pp. 45-51
-
-
Liu, Y.1
Liu, W.2
Song, X.-D.3
Zuo, J.4
-
11
-
-
77958479016
-
Dissecting the role of the mitochondrial chaperone mortalin in Parkinson's disease: Functional impact of disease-Related variants on mitochondrial homeostasis
-
Burbulla LF, Schelling C, Kato H, Rapaport D, Woitalla D, Schiesling C, Schulte C, Sharma M, Illig T, Bauer P, Jung S, Nordheim A, Schöls L, Riess O, Krüger R (2010) Dissecting the role of the mitochondrial chaperone mortalin in Parkinson's disease: Functional impact of disease-Related variants on mitochondrial homeostasis. Hum Mol Genet 19:4437-4452.
-
(2010)
Hum Mol Genet
, vol.19
, pp. 4437-4452
-
-
Burbulla, L.F.1
Schelling, C.2
Kato, H.3
Rapaport, D.4
Woitalla, D.5
Schiesling, C.6
Schulte, C.7
Sharma, M.8
Illig, T.9
Bauer, P.10
Jung, S.11
Nordheim, A.12
Schöls, L.13
Riess, O.14
Krüger, R.15
-
12
-
-
0036346345
-
Hsp70 family member, mot-2/ mthsp70/GRP75, binds to the cytoplasmic sequestration domain of the p53 protein
-
Wadhwa R (2002) Hsp70 family member, mot-2/ mthsp70/GRP75, binds to the cytoplasmic sequestration domain of the p53 protein. Exp Cell Res 274:246-253.
-
(2002)
Exp Cell Res
, vol.274
, pp. 246-253
-
-
Wadhwa, R.1
-
13
-
-
0032491426
-
Inactivation of tumor suppressor p53 by mot-2, a hsp70 family member
-
Wadhwa R, Takano S, Robert M, Yoshida A, Nomura H, Reddel RR, Mitsui Y, Kaul SC (1998) Inactivation of tumor suppressor p53 by mot-2, a hsp70 family member. J Biol Chem 273:29586-29591.
-
(1998)
J Biol Chem
, vol.273
, pp. 29586-29591
-
-
Wadhwa, R.1
Takano, S.2
Robert, M.3
Yoshida, A.4
Nomura, H.5
Reddel, R.R.6
Mitsui, Y.7
Kaul, S.C.8
-
14
-
-
11144349225
-
Mortalin is over-Expressed by colorectal adenocarcinomas and correlates with poor survival
-
Dundas SR, Lawrie LC, Rooney PH, Murray GI (2005) Mortalin is over-Expressed by colorectal adenocarcinomas and correlates with poor survival. J Pathol 205: 74-81.
-
(2005)
J Pathol
, vol.205
, pp. 74-81
-
-
Dundas, S.R.1
Lawrie, L.C.2
Rooney, P.H.3
Murray, G.I.4
-
15
-
-
33646409045
-
Upregulation of mortalin/mthsp70/Grp75 contributes to human carcinogenesis
-
Wadhwa R, Takano S, Kaur K, Deocaris CC, Pereira- Smith OM, Reddel RR, Kaul SC (2006) Upregulation of mortalin/mthsp70/Grp75 contributes to human carcinogenesis. Int J Cancer 118:2973-2980.
-
(2006)
Int J Cancer
, vol.118
, pp. 2973-2980
-
-
Wadhwa, R.1
Takano, S.2
Kaur, K.3
Deocaris, C.C.4
Pereira-Smith, O.M.5
Reddel, R.R.6
Kaul, S.C.7
-
16
-
-
33646496005
-
Mortalin-Based cytoplasmic sequestration of p53 in a nonmammalian cancer model
-
Walker C, Böttger S, Low B (2006) Mortalin-Based cytoplasmic sequestration of p53 in a nonmammalian cancer model. Am J Pathol 168:1526-1530.
-
(2006)
Am J Pathol
, vol.168
, pp. 1526-1530
-
-
Walker, C.1
Böttger, S.2
Low, B.3
-
17
-
-
0033256455
-
NIH 3T3 cells malignantly transformed by mot-2 show inactivation and cytoplasmic sequestration of the p53 protein
-
Wadhwa R, Takano S, Mitsui Y, Kaul SC (1999) NIH 3T3 cells malignantly transformed by mot-2 show inactivation and cytoplasmic sequestration of the p53 protein. Cell Res 9:261-269.
-
(1999)
Cell Res
, vol.9
, pp. 261-269
-
-
Wadhwa, R.1
Takano, S.2
Mitsui, Y.3
Kaul, S.C.4
-
18
-
-
33748286872
-
Mortalin controls centrosome duplication via modulating centrosomal localization of p53
-
Ma Z, Izumi H, Kanai M, Kabuyama Y, Ahn NG, Fukasawa K (2006) Mortalin controls centrosome duplication via modulating centrosomal localization of p53. Oncogene 25:5377-5390.
-
(2006)
Oncogene
, vol.25
, pp. 5377-5390
-
-
Ma, Z.1
Izumi, H.2
Kanai, M.3
Kabuyama, Y.4
Ahn, N.G.5
Fukasawa, K.6
-
19
-
-
84904256963
-
Functional characteristics of mortalin
-
Kaul S, Wadhwa R, Springer, New York
-
Baseler WA, Croston TL, Hollander JM, Functional Characteristics of Mortalin. In: Kaul S, Wadhwa R, Eds. (2012) Mortalin Biology: Life, Stress and Death. Springer, New York, pp 55-80.
-
(2012)
Mortalin Biology: Life, Stress and Death.
, pp. 55-80
-
-
Baseler, W.A.1
Croston, T.L.2
Hollander, J.M.3
-
20
-
-
84904247615
-
Mortalin expression in normal and neoplastic tissues
-
Kaul S, Wadhwa R, New York: Springer
-
Nomikos A, Dundas SR, Murray GI, Mortalin expression in normal and neoplastic tissues. In: Kaul S, Wadhwa R, Eds. (2012) Mortalin biology: life, stress and death. New York: Springer, pp 257-265.
-
(2012)
Mortalin Biology: Life, Stress and Death.
, pp. 257-265
-
-
Nomikos, A.1
Dundas, S.R.2
Murray, G.I.3
-
21
-
-
78651071860
-
Mortalin overexpression attenuates beta-Amyloidinduced neurotoxicity in SH-SY5Y cells
-
Qu M, Zhou Z, Xu S, Chen C, Yu Z, Wang D (2011) Mortalin overexpression attenuates beta-amyloidinduced neurotoxicity in SH-SY5Y cells. Brain Res 1368:336-345.
-
(2011)
Brain Res
, vol.1368
, pp. 336-345
-
-
Qu, M.1
Zhou, Z.2
Xu, S.3
Chen, C.4
Yu, Z.5
Wang, D.6
-
22
-
-
13644254746
-
Reduction in mortalin level by its antisense expression causes senescence-Like growth arrest in human immortalized cells
-
Wadhwa R, Takano S, Taira K, Kaul SC (2004) Reduction in mortalin level by its antisense expression causes senescence-Like growth arrest in human immortalized cells. J Gene Med 6:439-444.
-
(2004)
J Gene Med
, vol.6
, pp. 439-444
-
-
Wadhwa, R.1
Takano, S.2
Taira, K.3
Kaul, S.C.4
-
23
-
-
80052036411
-
Induction of mutant p53-Dependent apoptosis in human hepatocellular carcinoma by targeting stress protein mortalin
-
Lu W-J, Lee NP, Kaul SC, Lan F, Poon RTP, Wadhwa R, Luk JM (2011) Induction of mutant p53-Dependent apoptosis in human hepatocellular carcinoma by targeting stress protein mortalin. Int J Cancer 129:1806- 1814.
-
(2011)
Int J Cancer
, vol.129
, pp. 1806-1814
-
-
Lu, W.-J.1
Lee, N.P.2
Kaul, S.C.3
Lan, F.4
Poon, R.T.P.5
Wadhwa, R.6
Luk, J.M.7
-
24
-
-
34249291074
-
Mortalin sensitizes human cancer cells to MKT-077-Induced senescence
-
Deocaris CC, Widodo N, Shrestha BG, Kaur K, Ohtaka M, Yamasaki K, Kaul SC, Wadhwa R (2007) Mortalin sensitizes human cancer cells to MKT-077-induced senescence. Cancer Lett 252:259-269.
-
(2007)
Cancer Lett
, vol.252
, pp. 259-269
-
-
Deocaris, C.C.1
Widodo, N.2
Shrestha, B.G.3
Kaur, K.4
Ohtaka, M.5
Yamasaki, K.6
Kaul, S.C.7
Wadhwa, R.8
-
25
-
-
0034671731
-
Selective toxicity of MKT-077 to cancer cells is mediated by its binding to the hsp70 family protein mot-2 and reactivation of p53 function
-
Wadhwa R, Sugihara T, Yoshida A, Nomura H, Reddel RR, Simpson R, Maruta H, Kaul SC (2000) Selective toxicity of MKT-077 to cancer cells is mediated by its binding to the hsp70 family protein mot-2 and reactivation of p53 function. Cancer Res 60:6818-6821.
-
(2000)
Cancer Res
, vol.60
, pp. 6818-6821
-
-
Wadhwa, R.1
Sugihara, T.2
Yoshida, A.3
Nomura, H.4
Reddel, R.R.5
Simpson, R.6
Maruta, H.7
Kaul, S.C.8
-
26
-
-
74949095086
-
Mortalin inhibitors sensitize K562 leukemia cells to complement-Dependent cytotoxicity
-
Pilzer D, Saar M, Koya K, Fishelson Z (2010) Mortalin inhibitors sensitize K562 leukemia cells to complement-Dependent cytotoxicity. Int J Cancer 126: 1428-1435.
-
(2010)
Int J Cancer
, vol.126
, pp. 1428-1435
-
-
Pilzer, D.1
Saar, M.2
Koya, K.3
Fishelson, Z.4
-
27
-
-
0032834594
-
Phase i trial of the selective mitochondrial toxin MKT077 in chemoresistant solid tumours
-
Propper DJ, Braybrooke JP, Taylor DJ, Lodi R, Styles P, Cramer JA, Collins WC, Levitt NC, Talbot DC, Ganesan TS, Harris AL (1999) Phase I trial of the selective mitochondrial toxin MKT077 in chemoresistant solid tumours. Ann Oncol 10:923-927.
-
(1999)
Ann Oncol
, vol.10
, pp. 923-927
-
-
Propper, D.J.1
Braybrooke, J.P.2
Taylor, D.J.3
Lodi, R.4
Styles, P.5
Cramer, J.A.6
Collins, W.C.7
Levitt, N.C.8
Talbot, D.C.9
Ganesan, T.S.10
Harris, A.L.11
-
28
-
-
0033956563
-
A phase i and pharmacokinetic study of the mitochondrialspecific rhodacyanine dye analog MKT 077
-
Britten CD, Rowinsky EK, Baker SD, Weiss GR, Smith L, Stephenson J, Rothenberg M, Smetzer L, Cramer J, Collins W, Von Hoff DD, Eckhardt SG (2000) A phase I and pharmacokinetic study of the mitochondrialspecific rhodacyanine dye analog MKT 077. Clin Cancer Res 6:42-49.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 42-49
-
-
Britten, C.D.1
Rowinsky, E.K.2
Baker, S.D.3
Weiss, G.R.4
Smith, L.5
Stephenson, J.6
Rothenberg, M.7
Smetzer, L.8
Cramer, J.9
Collins, W.10
Von Hoff, D.D.11
Eckhardt, S.G.12
-
29
-
-
84874473589
-
Allostery in the Hsp70 chaperone proteins
-
Zuiderweg ERP, Bertelsen EB, Rousaki A, Mayer MP, Gestwicki JE, Ahmad A (2013) Allostery in the Hsp70 chaperone proteins. Top Curr Chem 328:99-153.
-
(2013)
Top Curr Chem
, vol.328
, pp. 99-153
-
-
Zuiderweg, E.R.P.1
Bertelsen, E.B.2
Rousaki, A.3
Mayer, M.P.4
Gestwicki, J.E.5
Ahmad, A.6
-
30
-
-
79960927001
-
Allosteric drugs: The interaction of antitumor compound MKT-077 with human Hsp70 chaperones
-
Rousaki A, Miyata Y, Jinwal UK, Dickey CA, Gestwicki JE, Zuiderweg ERP (2011) Allosteric drugs: The interaction of antitumor compound MKT-077 with human Hsp70 chaperones. J Mol Biol 411:614-632.
-
(2011)
J Mol Biol
, vol.411
, pp. 614-632
-
-
Rousaki, A.1
Miyata, Y.2
Jinwal, U.K.3
Dickey, C.A.4
Gestwicki, J.E.5
Zuiderweg, E.R.P.6
-
31
-
-
79960691369
-
Biochemical and structural studies on the high affinity of Hsp70 for ADP
-
Arakawa A, Handa N, Shirouzu M, Yokoyama S (2011) Biochemical and structural studies on the high affinity of Hsp70 for ADP. Protein Sci 20:1367-1379.
-
(2011)
Protein Sci
, vol.20
, pp. 1367-1379
-
-
Arakawa, A.1
Handa, N.2
Shirouzu, M.3
Yokoyama, S.4
-
32
-
-
77954288774
-
Dali server: Conservation mapping in 3D
-
Holm L, Rosenström P (2010) Dali server: Conservation mapping in 3D. Nucleic Acids Res 38:W545-W549.
-
(2010)
Nucleic Acids Res
, vol.38
-
-
Holm, L.1
Rosenström, P.2
-
33
-
-
77649158380
-
Direct inter-Subdomain interactions switch between the closed and open forms of the Hsp70 nucleotide-Binding domain in the nucleotide-Free state
-
Shida M, Arakawa A, Ishii R, Kishishita S, Takagi T, Kukimoto-Niino M, Sugano S, Tanaka A, Shirouzu M, Yokoyama S (2010) Direct inter-Subdomain interactions switch between the closed and open forms of the Hsp70 nucleotide-Binding domain in the nucleotide-Free state. Acta Crystallogr D66:223-232.
-
(2010)
Acta Crystallogr D
, vol.66
, pp. 223-232
-
-
Shida, M.1
Arakawa, A.2
Ishii, R.3
Kishishita, S.4
Takagi, T.5
Kukimoto-Niino, M.6
Sugano, S.7
Tanaka, A.8
Shirouzu, M.9
Yokoyama, S.10
-
34
-
-
0035041855
-
Tuning of chaperone activity of Hsp70 proteins by modulation of nucleotide exchange
-
Brehmer D, Rüdiger S, Gässler CS, Klostermeier D, Packschies L, Reinstein J, Mayer MP, Bukau B (2001) Tuning of chaperone activity of Hsp70 proteins by modulation of nucleotide exchange. Nat Struct Biol 8:427-432.
-
(2001)
Nat Struct Biol
, vol.8
, pp. 427-432
-
-
Brehmer, D.1
Rüdiger, S.2
Gässler, C.S.3
Klostermeier, D.4
Packschies, L.5
Reinstein, J.6
Mayer, M.P.7
Bukau, B.8
-
35
-
-
0034837025
-
ATPase-Defective derivatives of Escherichia coli DnaK that behave differently with respect to ATP-induced conformational change and peptide release
-
Barthel TK, Zhang J, Walker GC (2001) ATPase-Defective derivatives of Escherichia coli DnaK that behave differently with respect to ATP-induced conformational change and peptide release. J Bacteriol 183:5482-5490.
-
(2001)
J Bacteriol
, vol.183
, pp. 5482-5490
-
-
Barthel, T.K.1
Zhang, J.2
Walker, G.C.3
-
36
-
-
0028240468
-
Structural basis of the 70-kilodalton heat shock cognate protein ATP hydrolytic activity. II. Structure of the active site with ADP or ATP bound to wild type and mutant ATPase fragment
-
Flaherty KM, Wilbanks SM, DeLuca-Flaherty C, McKay DB (1994) Structural basis of the 70-kilodalton heat shock cognate protein ATP hydrolytic activity. II. Structure of the active site with ADP or ATP bound to wild type and mutant ATPase fragment. J Biol Chem 269:12899-12907.
-
(1994)
J Biol Chem
, vol.269
, pp. 12899-12907
-
-
Flaherty, K.M.1
Wilbanks, S.M.2
Deluca-Flaherty, C.3
McKay, D.B.4
-
37
-
-
84878617377
-
Real-Time observation of the conformational dynamics of mitochondrial Hsp70 by spFRET
-
Sikor M, Mapa K, Voithenberg von LV, Mokranjac D, Lamb DC (2013) Real-Time observation of the conformational dynamics of mitochondrial Hsp70 by spFRET. EMBO J 32:1639-1649.
-
(2013)
EMBO J
, vol.32
, pp. 1639-1649
-
-
Sikor, M.1
Mapa, K.2
Voithenberg Von, L.V.3
Mokranjac, D.4
Lamb, D.C.5
-
38
-
-
70349238601
-
Mutational screening of the mortalin gene (HSPA9) in Parkinson's disease.
-
De Mena L, Coto E, Sánchez-Ferrero E, Ribacoba R, Guisasola LM, Salvador C, Blázquez M, Alvarez V (2009) Mutational screening of the mortalin gene (HSPA9) in Parkinson's disease. J Neural Transm 116: 1289-1293.
-
(2009)
J Neural Transm
, vol.116
, pp. 1289-1293
-
-
De Mena, L.1
Coto, E.2
Sánchez-Ferrero, E.3
Ribacoba, R.4
Guisasola, L.M.5
Salvador, C.6
Blázquez, M.7
Alvarez, V.8
-
39
-
-
84864517463
-
Enhanced J-Protein interaction and compromised protein stability of mtHsp70 variants lead to mitochondrial dysfunction in Parkinson's disease
-
Goswami AV, Samaddar M, Sinha D, Purushotham J, D'Silva P (2012) Enhanced J-Protein interaction and compromised protein stability of mtHsp70 variants lead to mitochondrial dysfunction in Parkinson's disease. Hum Mol Genet 21:3317-3332.
-
(2012)
Hum Mol Genet
, vol.21
, pp. 3317-3332
-
-
Goswami, A.V.1
Samaddar, M.2
Sinha, D.3
Purushotham, J.4
D'Silva, P.5
-
40
-
-
84858955705
-
Reactivation of protein aggregates by mortalin and Tid1-The human mitochondrial Hsp70 chaperone system
-
Iosefson O, Sharon S, Goloubinoff P, Azem A (2012) Reactivation of protein aggregates by mortalin and Tid1-The human mitochondrial Hsp70 chaperone system. Cell Stress Chaperones 17:57-66.
-
(2012)
Cell Stress Chaperones
, vol.17
, pp. 57-66
-
-
Iosefson, O.1
Sharon, S.2
Goloubinoff, P.3
Azem, A.4
-
41
-
-
0032516866
-
Evidence for the existence of distinct mammalian cytosolic, microsomal, and two mitochondrial GrpE-Like proteins, the Co-Chaperones of specific Hsp70 members
-
Naylor DJ, Stines AP, Hoogenraad NJ, Høj PB (1998) Evidence for the existence of distinct mammalian cytosolic, microsomal, and two mitochondrial GrpE-Like proteins, the Co-Chaperones of specific Hsp70 members. J Biol Chem 273:21169-21177.
-
(1998)
J Biol Chem
, vol.273
, pp. 21169-21177
-
-
Naylor, D.J.1
Stines, A.P.2
Hoogenraad, N.J.3
Høj, P.B.4
-
42
-
-
0035804671
-
Identification and characterization of a human mitochondrial homologue of the bacterial co-Chaperone GrpE
-
Choglay AA, Chapple JP, Blatch GL, Cheetham ME (2001) Identification and characterization of a human mitochondrial homologue of the bacterial co-Chaperone GrpE. Gene 267:125-134.
-
(2001)
Gene
, vol.267
, pp. 125-134
-
-
Choglay, A.A.1
Chapple, J.P.2
Blatch, G.L.3
Cheetham, M.E.4
-
43
-
-
0030936995
-
Crystal structure of the nucleotide exchange factor GrpE bound to the ATPase domain of the molecular chaperone DnaK
-
Harrison CJ, Hayer-Hartl M, Di Liberto M, Hartl F, Kuriyan J (1997) Crystal structure of the nucleotide exchange factor GrpE bound to the ATPase domain of the molecular chaperone DnaK. Science 276:431-435.
-
(1997)
Science
, vol.276
, pp. 431-435
-
-
Harrison, C.J.1
Hayer-Hartl, M.2
Di Liberto, M.3
Hartl, F.4
Kuriyan, J.5
-
44
-
-
84862289262
-
Crystal structure of DnaK protein complexed with nucleotide exchange factor GrpE in DnaK chaperone system: Insight into intermolecular communication
-
Wu C-C, Naveen V, Chien C-H, Chang Y-W, Hsiao C-D (2012) Crystal structure of DnaK protein complexed with nucleotide exchange factor GrpE in DnaK chaperone system: Insight into intermolecular communication. J Biol Chem 287:21461-21470.
-
(2012)
J Biol Chem
, vol.287
, pp. 21461-21470
-
-
Wu, C.-C.1
Naveen, V.2
Chien, C.-H.3
Chang, Y.-W.4
Hsiao, C.-D.5
-
46
-
-
84871689599
-
Structure and dynamics of the ATP-Bound open conformation of Hsp70 chaperones
-
Kityk R, Kopp J, Sinning I, Mayer MP (2012) Structure and dynamics of the ATP-Bound open conformation of Hsp70 chaperones. Mol Cell 48:863-874.
-
(2012)
Mol Cell
, vol.48
, pp. 863-874
-
-
Kityk, R.1
Kopp, J.2
Sinning, I.3
Mayer, M.P.4
-
47
-
-
84880167772
-
Allosteric opening of the polypeptide-Binding site when an Hsp70 binds ATP
-
Qi R, Sarbeng EB, Liu Q, Le KQ, Xu X, Xu H, Yang J, Wong JL, Vorvis C, Hendrickson WA, Zhou L, Liu Q (2013) Allosteric opening of the polypeptide-Binding site when an Hsp70 binds ATP. Nat Struct Mol Biol 20: 900-907.
-
(2013)
Nat Struct Mol Biol
, vol.20
, pp. 900-907
-
-
Qi, R.1
Sarbeng, E.B.2
Liu, Q.3
Le Xu, K.Q.X.4
Xu, H.5
Yang, J.6
Wong, J.L.7
Vorvis, C.8
Hendrickson, W.A.9
Zhou, L.10
Liu, Q.11
-
48
-
-
28244470279
-
Activation of wild type p53 function by its mortalinbinding, cytoplasmically localizing carboxyl terminus peptides
-
Kaul SC, Aida S, Yaguchi T, Kaur K, Wadhwa R (2005) Activation of wild type p53 function by its mortalinbinding, cytoplasmically localizing carboxyl terminus peptides. J Biol Chem 280:39373-39379.
-
(2005)
J Biol Chem
, vol.280
, pp. 39373-39379
-
-
Kaul, S.C.1
Aida, S.2
Yaguchi, T.3
Kaur, K.4
Wadhwa, R.5
-
49
-
-
77950370585
-
Reconstitution of the mitochondrial Hsp70 (mortalin)-P53 interaction using purified proteins-Identification of additional interacting regions
-
Iosefson O, Azem A (2010) Reconstitution of the mitochondrial Hsp70 (mortalin)-P53 interaction using purified proteins-Identification of additional interacting regions. FEBS Lett 584:1080-1084.
-
(2010)
FEBS Lett
, vol.584
, pp. 1080-1084
-
-
Iosefson, O.1
Azem, A.2
-
50
-
-
84861675066
-
Specific recognition of p53 tetramers by peptides derived from p53 interacting proteins
-
Gabizon R, Brandt T, Sukenik S, Lahav N, Lebendiker M, Shalev DE, Veprintsev D, Friedler A (2012) Specific recognition of p53 tetramers by peptides derived from p53 interacting proteins. PLoS ONE 7:e38060.
-
(2012)
PLoS ONE
, vol.7
-
-
Gabizon, R.1
Brandt, T.2
Sukenik, S.3
Lahav, N.4
Lebendiker, M.5
Shalev, D.E.6
Veprintsev, D.7
Friedler, A.8
-
51
-
-
77649190277
-
Tid1 is a new regulator of p53 mitochondrial translocation and apoptosis in cancer
-
Ahn BY, Trinh DLN, Zajchowski LD, Lee B, Elwi AN, Kim SW (2009) Tid1 is a new regulator of p53 mitochondrial translocation and apoptosis in cancer. Oncogene 29:1155-1166.
-
(2009)
Oncogene
, vol.29
, pp. 1155-1166
-
-
Ahn, B.Y.1
Trinh, D.L.N.2
Zajchowski, L.D.3
Lee, B.4
Elwi, A.N.5
Kim, S.W.6
-
52
-
-
79957464247
-
Direct interaction between p53 and Tid1 proteins affects p53 mitochondrial localization and apoptosisy as a target for cancer therapy?
-
Trinh DLN, Elwi AN, Kim S-W (2010) Direct interaction between p53 and Tid1 proteins affects p53 mitochondrial localization and apoptosisy as a target for cancer therapy? Oncotarget 1:405-422.
-
(2010)
Oncotarget
, vol.1
, pp. 405-422
-
-
Trinh, D.L.N.1
Elwi, A.N.2
Kim, S.-W.3
-
53
-
-
82755187767
-
Heat shock protein 70 kDa chaperone/DnaJ cochaperone complex employs an unusual dynamic interface
-
Ahmad A, Bhattacharya A, McDonald RA, Cordes M, Ellington B, Bertelsen EB, Zuiderweg ERP (2011) Heat shock protein 70 kDa chaperone/DnaJ cochaperone complex employs an unusual dynamic interface. Proc Natl Acad Sci USA 108:18966-18971.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 18966-18971
-
-
Ahmad, A.1
Bhattacharya, A.2
McDonald, R.A.3
Cordes, M.4
Ellington, B.5
Bertelsen, E.B.6
Zuiderweg, E.R.P.7
-
55
-
-
0033082686
-
Overcoming expression and purification problems of RhoGDI using a family of "parallel" expression vectors
-
Sheffield P, Garrard S, Derewenda Z (1999) Overcoming expression and purification problems of RhoGDI using a family of "parallel" expression vectors. Protein Expr Purif 15:34-39.
-
(1999)
Protein Expr Purif
, vol.15
, pp. 34-39
-
-
Sheffield, P.1
Garrard, S.2
Derewenda, Z.3
-
56
-
-
0035711194
-
Tobacco etch virus protease: Mechanism of autolysis and rational design of stable mutants with wild-Type catalytic proficiency
-
Kapust RB, Tózsér J, Fox JD, Anderson DE, Cherry S, Copeland TD, Waugh DS (2001) Tobacco etch virus protease: Mechanism of autolysis and rational design of stable mutants with wild-Type catalytic proficiency. Protein Eng 14:993-1000.
-
(2001)
Protein Eng
, vol.14
, pp. 993-1000
-
-
Kapust, R.B.1
Tózsér, J.2
Fox, J.D.3
Anderson, D.E.4
Cherry, S.5
Copeland, T.D.6
Waugh, D.S.7
-
58
-
-
34447508216
-
Phaser crystallographic software
-
McCoy AJ, Grosse-Kunstleve RW, Adams PD, Winn MD, Storoni LC, Read RJ (2007) Phaser crystallographic software. J Appl Crystallogr 40:658-674.
-
(2007)
J Appl Crystallogr
, vol.40
, pp. 658-674
-
-
McCoy, A.J.1
Grosse-Kunstleve, R.W.2
Adams, P.D.3
Winn, M.D.4
Storoni, L.C.5
Read, R.J.6
-
59
-
-
76449098262
-
PHENIX: A comprehensive Python-Based system for macromolecular structure solution
-
Adams PD, Afonine PV, Bunkóczi G, Chen VB, Davis IW, Echols N, Headd JJ, Hung L-W, Kapral GJ, Grosse-Kunstleve RW, McCoy AJ, Moriarty NW, Oeffner R, Read RJ, Richardson DC, Richardson JS, Terwilliger TC, Zwart PH (2010) PHENIX: A comprehensive Python-Based system for macromolecular structure solution. Acta Crystallogr D66:213-221.
-
(2010)
Acta Crystallogr D
, vol.66
, pp. 213-221
-
-
Adams, P.D.1
Afonine, P.V.2
Bunkóczi, G.3
Chen, V.B.4
Davis, I.W.5
Echols, N.6
Headd, J.J.7
Hung, L.-W.8
Kapral, G.J.9
Grosse-Kunstleve, R.W.10
McCoy, A.J.11
Moriarty, N.W.12
Oeffner, R.13
Read, R.J.14
Richardson, D.C.15
Richardson, J.S.16
Terwilliger, T.C.17
Zwart, P.H.18
-
60
-
-
37349103121
-
Iterative model building, structure refinement and density modification with the PHENIX Auto- Build wizard
-
Terwilliger TC, Grosse-Kunstleve RW, Afonine PV, Moriarty NW, Zwart PH, Hung L-W, Read RJ, Adams PD (2008) Iterative model building, structure refinement and density modification with the PHENIX Auto- Build wizard. Acta Crystallogr D64:61-69.
-
(2008)
Acta Crystallogr D
, vol.64
, pp. 61-69
-
-
Terwilliger, T.C.1
Grosse-Kunstleve, R.W.2
Afonine, P.V.3
Moriarty, N.W.4
Zwart, P.H.5
Hung, L.-W.6
Read, R.J.7
Adams, P.D.8
-
62
-
-
74549178560
-
MolProbity: All-atom structure validation for macromolecular crystallography
-
Chen VB, Arendall WB, Headd JJ, Keedy DA, Immormino RM, Kapral GJ, Murray LW, Richardson JS, Richardson DC (2010) MolProbity: All-atom structure validation for macromolecular crystallography. Acta Crystallogr D66:12-21.
-
(2010)
Acta Crystallogr D
, vol.66
, pp. 12-21
-
-
Chen, V.B.1
Arendall, W.B.2
Headd, J.J.3
Keedy, D.A.4
Immormino, R.M.5
Kapral, G.J.6
Murray, L.W.7
Richardson, J.S.8
Richardson, D.C.9
-
64
-
-
0035964342
-
Electrostatics of nanosystems: Application to microtubules and the ribosome
-
Baker NA, Sept D, Joseph S, Holst MJ, McCammon JA (2001) Electrostatics of nanosystems: Application to microtubules and the ribosome. Proc Natl Acad Sci USA 98:10037-10041.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 10037-10041
-
-
Baker, N.A.1
Sept, D.2
Joseph, S.3
Holst, M.J.4
McCammon, J.A.5
-
65
-
-
77954065271
-
I-TASSER: A unified platform for automated protein structure and function prediction
-
Roy A, Kucukural A, Zhang Y (2010) I-TASSER: A unified platform for automated protein structure and function prediction. Nat Protoc 5:725-738.
-
(2010)
Nat Protoc
, vol.5
, pp. 725-738
-
-
Roy, A.1
Kucukural, A.2
Zhang, Y.3
-
66
-
-
67849110427
-
Structure prediction for CASP8 with all-Atom refinement using Rosetta
-
Raman S, Vernon R, Thompson J, Tyka M, Sadreyev R, Pei J, Kim D, Kellogg E, DiMaio F, Lange O, Kinch L, Sheffler W, Kim B-H, Das R, Grishin NV, Baker D (2009) Structure prediction for CASP8 with all-atom refinement using Rosetta. Proteins 77 (Suppl 9):89-99.
-
(2009)
Proteins
, vol.77
, Issue.SUPPL.9
, pp. 89-99
-
-
Raman, S.1
Vernon, R.2
Thompson, J.3
Tyka, M.4
Sadreyev, R.5
Pei, J.6
Kim, D.7
Kellogg, E.8
Dimaio, F.9
Lange, O.10
Kinch, L.11
Sheffler, W.12
Kim, B.-H.13
Das, R.14
Grishin, N.V.15
Baker, D.16
-
67
-
-
33750210515
-
Homology modeling using parametric alignment ensemble generation with consensus and energy-Based model selection
-
Chivian D, Baker D (2006) Homology modeling using parametric alignment ensemble generation with consensus and energy-Based model selection. Nucleic Acids Res 34:e112.
-
(2006)
Nucleic Acids Res
, vol.34
-
-
Chivian, D.1
Baker, D.2
-
68
-
-
79961012919
-
Benchmarking and analysis of protein docking performance in Rosetta v3.2
-
Chaudhury S, Berrondo M, Weitzner BD, Muthu P, Bergman H, Gray JJ (2011) Benchmarking and analysis of protein docking performance in Rosetta v3.2. PLoS ONE 6:e22477.
-
(2011)
PLoS ONE
, vol.6
-
-
Chaudhury, S.1
Berrondo, M.2
Weitzner, B.D.3
Muthu, P.4
Bergman, H.5
Gray, J.J.6
-
69
-
-
79955716232
-
Rosetta FlexPepDock ab-Initio: Simultaneous folding, docking and refinement of peptides onto their receptors
-
Raveh B, London N, Zimmerman L, Schueler-Furman O (2011) Rosetta FlexPepDock ab-initio: Simultaneous folding, docking and refinement of peptides onto their receptors. PLoS ONE 6:e18934.
-
(2011)
PLoS ONE
, vol.6
-
-
Raveh, B.1
London, N.2
Zimmerman, L.3
Schueler-Furman, O.4
-
70
-
-
70349597601
-
Electronic Ligand Builder and Optimization Workbench (eLBOW): A tool for ligand coordinate and restraint generation
-
Moriarty NW, Grosse-Kunstleve RW, Adams PD (2009) electronic Ligand Builder and Optimization Workbench (eLBOW): A tool for ligand coordinate and restraint generation. Acta Crystallogr D65:1074-1080.
-
(2009)
Acta Crystallogr D
, vol.65
, pp. 1074-1080
-
-
Moriarty, N.W.1
Grosse-Kunstleve, R.W.2
Adams, P.D.3
-
71
-
-
58149094776
-
RosettaLigand docking with full ligand and receptor flexibility
-
Davis IW, Baker D (2009) RosettaLigand docking with full ligand and receptor flexibility. J Mol Biol 385:381-392.
-
(2009)
J Mol Biol
, vol.385
, pp. 381-392
-
-
Davis, I.W.1
Baker, D.2
|