Response of the human detrusor to stretch is regulated by TREK-1, a two-pore-domain (K2P) mechano-gated potassium channel

Journal of Physiology

Volumn 592, Issue 14, 2014, Pages 3013-3030

  Lei, Qi ^a   Pan, Xiao Qing ^a   Chang, Shaohua ^b   Malkowicz, S Bruce ^a   Guzzo, Thomas J ^a   Malykhina, Anna P ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b Center for Dermatologic Surgery   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARACHIDONIC ACID; CATION CHANNEL; POTASSIUM CHANNEL; PROTEIN TRAAK; PROTEIN TREK 1; PROTEIN TREK 2; UNCLASSIFIED DRUG; KCNK10 PROTEIN, HUMAN; KCNK4 PROTEIN, HUMAN; POTASSIUM CHANNEL PROTEIN TREK-1; TANDEM PORE DOMAIN POTASSIUM CHANNEL;

ADULT; AGED; ARTICLE; BIOPHYSICS; BLADDER MUCOSA; BLADDER MUSCLE; BLADDER WALL; CELL ADHESION; CELL MEMBRANE; CONTROLLED STUDY; DETRUSOR MUSCLE; ELECTROPHYSIOLOGICAL PROCEDURES; FEMALE; GENETIC ANALYSIS; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MALE; MUSCLE STRETCHING; PATCH CLAMP TECHNIQUE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN LOCALIZATION; SMOOTH MUSCLE CONTRACTILITY; SMOOTH MUSCLE FIBER; SMOOTH MUSCLE RELAXATION; BLADDER; METABOLISM; MIDDLE AGED; MUSCLE CONTRACTION; PHYSIOLOGY; SMOOTH MUSCLE;

ADULT; AGED; FEMALE; HUMANS; IN VITRO TECHNIQUES; MALE; MIDDLE AGED; MUSCLE CONTRACTION; MUSCLE, SMOOTH; POTASSIUM CHANNELS; POTASSIUM CHANNELS, TANDEM PORE DOMAIN; URINARY BLADDER;

EID: 84904255481     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2014.271718     Document Type: Article

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