Differential effects of intravesical resiniferatoxin on excitability of bladder spinal neurons upon colon-bladder cross-sensitization

Brain Research

Volumn 1491, Issue , 2013, Pages 213-224

  Malykhina, Anna P ^a   Qin, Chao ^b   Lei, Qi ^a   Pan, Xiao Qing ^a   Greenwood Van Meerveld, Beverley ^b,c,d   Foreman, Robert D ^b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

^c UNIVERSITY OF OKLAHOMA HEALTH SCIENCES CENTER   (United States)

^d VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Bladder pain syndrome; Chronic pelvic pain; Intravesical vanilloids; Spinal neurons

Indexed keywords

RESINIFERATOXIN; TRINITROBENZENESULFONIC ACID; VANILLOID RECEPTOR 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLADDER DISTENSION; BLADDER INNERVATION; COLITIS; CONTROLLED STUDY; CROSS ALLERGY; CYSTALGIA; DRUG EFFECT; HYPOTHESIS; INTERSTITIAL CYSTITIS; LUMBOSACRAL PLEXUS; MALE; MOLECULAR INTERACTION; NERVE EXCITABILITY; NERVOUS SYSTEM ELECTROPHYSIOLOGY; NONHUMAN; PELVIS PAIN SYNDROME; PRIORITY JOURNAL; RAT; RECEPTOR DOWN REGULATION; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION; SPINAL CORD NERVE CELL;

ANIMALS; BLOTTING, WESTERN; COLITIS; COLON; DATA INTERPRETATION, STATISTICAL; DITERPENES; LUMBOSACRAL PLEXUS; MALE; NEURONS; NEURONS, AFFERENT; PHYSICAL STIMULATION; RATS; RATS, SPRAGUE-DAWLEY; TRINITROBENZENESULFONIC ACID; TRPV CATION CHANNELS; URINARY BLADDER; URINARY BLADDER DISEASES;

RATTUS;

EID: 84874018637     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2012.11.003     Document Type: Article

References (48)

1. A. Apostolidis, C.M. Brady, Y. Yiangou, J. Davis, C.J. Fowler, and P. Anand Capsaicin receptor TRPV1 in urothelium of neurogenic human bladders and effect of intravesical resiniferatoxin Urology 65 2005 400 405
2. T.S. Asfaw, J. Hypolite, G.M. Northington, L.A. Arya, A.J. Wein, and A.P. Malykhina Acute colonic inflammation triggers detrusor instability via activation of TRPV1 receptors in a rat model of pelvic organ cross-sensitization Am. J. Physiol. 300 2011 R1392 R1400
3. A. Avelino, and F. Cruz TRPV1 (vanilloid receptor) in the urinary tract: expression, function and clinical applications Naunyn Schmiedebergs Arch. Pharmacol. 373 2006 287 299
4. K. Bielefeldt, K. Lamb, and G.F. Gebhart Convergence of sensory pathways in the development of somatic and visceral hypersensitivity Am. J. Physiol 291 2006 G658 G665
5. L.A. Birder, A.J. Kanai, W.C. de Groat, S. Kiss, M.L. Nealen, N.E. Burke, K.E. Dineley, S. Watkins, I.J. Reynolds, and M.J. Caterina Vanilloid receptor expression suggests a sensory role for urinary bladder epithelial cells Proc. Natl. Acad. Sci. USA 98 2001 13396 13401
6. L.A. Birder, Y. Nakamura, S. Kiss, M.L. Nealen, S. Barrick, A.J. Kanai, E. Wang, G. Ruiz, W.C. de Groat, G. Apodaca, S. Watkins, and M.J. Caterina Altered urinary bladder function in mice lacking the vanilloid receptor TRPV1 Nat. Neurosci. 5 2002 856 860
7. K. Bon, C.A. Lichtensteiger, S.G. Wilson, and J.S. Mogil Characterization of cyclophosphamide cystitis, a model of visceral and referred pain, in the mouse: species and strain differences J. Urol. 170 2003 1008 1012
8. P.R. Brumovsky, B. Feng, L. Xu, C.J. McCarthy, and G.F. Gebhart Cystitis increases colorectal afferent sensitivity in the mouse Am. J. Physiol. 297 2009 G1250 G1258
9. P.R. Brumovsky, and G.F. Gebhart Visceral organ cross-sensitization - an integrated perspective Auton. Neurosci. 153 2010 106 115
10. M.J. Caterina, A. Leffler, A.B. Malmberg, W.J. Martin, J. Trafton, K.R. Petersen-Zeitz, M. Koltzenburg, A.I. Basbaum, and D. Julius Impaired nociception and pain sensation in mice lacking the capsaicin receptor Science 288 2000 306 313
11. M.J. Caterina, M.A. Schumacher, M. Tominaga, T.A. Rosen, J.D. Levine, and D. Julius The capsaicin receptor: a heat-activated ion channel in the pain pathway Nature 389 1997 816 824
12. F. Cervero Somatic and visceral inputs to the thoracic spinal cord of the cat: effects of noxious stimulation of the biliary system J. Physiol. 337 1983 51 67
13. M.J. Chandler, C. Qin, J. Zhang, and R.D. Foreman Differential effects of urinary bladder distension on high cervical projection neurons in primates Brain Res. 949 2002 97 104
14. A. Charrua, C. Reguenga, J.M. Cordeiro, P. Correiade-Sa, C. Paule, I. Nagy, F. Cruz, and A. Avelino Functional transient receptor potential vanilloid 1 is expressed in human urothelial cells J. Urol. 182 2009 2944 2950
15. T.Y. Chen, J. Corcos, M. Camel, Y. Ponsot, and le M. Tu Prospective, randomized, double-blind study of safety and tolerability of intravesical resiniferatoxin (RTX) in interstitial cystitis (IC) Int. Urogynecol. J. Pelvic Floor Dysfunct. 16 2005 293 297
16. J.A. Christianson, R. Liang, E.E. Ustinova, B.M. Davis, M.O. Fraser, and M.A. Pezzone Convergence of bladder and colon sensory innervation occurs at the primary afferent level Pain 128 2007 235 243
17. W.C. DeGroat Inhibition and excitation of sacral parasympathetic neurons by visceral and cutaneous stimuli in the cat Brain Res. 33 1971 499 503
18. W. Everaerts, J. Vriens, G. Owsianik, G. Appendino, T. Voets, R.D. De, and B. Nilius Functional characterization of transient receptor potential channels in mouse urothelial cells Am. J. Physiol. 298 2010 F692 F701
19. C. Goso, G. Piovacari, and A. Szallasi Resiniferatoxin-induced loss of vanilloid receptors is reversible in the urinary bladder but not in the spinal cord of the rat Neurosci. Lett. 162 1993 197 200
20. P.M. Hanno, D.A. Burks, J.Q. Clemens, R.R. Dmochowski, D. Erickson, M.P. Fitzgerald, J.B. Forrest, B. Gordon, M. Gray, R.D. Mayer, D. Newman, L. Nyberg Jr, C.K. Payne, U. Wesselmann, and M.M. Faraday AUA guideline for the diagnosis and treatment of interstitial cystitis/bladder pain syndrome J. Urol. 185 2011 2162 2170
21. S.J. Hwang, J.M. Oh, and J.G. Valtschanoff Expression of the vanilloid receptor TRPV1 in rat dorsal root ganglion neurons supports different roles of the receptor in visceral and cutaneous afferents Brain Res. 1047 2005 261 266
22. S.I. Jaggar, H.C. Scott, I.F. James, and A.S. Rice The capsaicin analogue SDZ249-665 attenuates the hyper-reflexia and referred hyperalgesia associated with inflammation of the rat urinary bladder Pain 89 2001 229 235
23. J.A. Jeffry, S.Q. Yu, P. Sikand, A. Parihar, M.S. Evans, and L.S. Premkumar Selective targeting of TRPV1 expressing sensory nerve terminals in the spinal cord for long lasting analgesia PLoS One 4 2009 e7021
24. J.H. Kim, D.A. Rivas, P.J. Shenot, B. Green, M. Kennelly, J.R. Erickson, M. O'Leary, N. Yoshimura, and M.B. Chancellor Intravesical resiniferatoxin for refractory detrusor hyperreflexia: a multicenter, blinded, randomized, placebo-controlled trial J. Spinal Cord Med. 26 2003 358 363
25. K. Lamb, F. Zhong, G.F. Gebhart, and K. Bielefeldt Experimental colitis in mice and sensitization of converging visceral and somatic afferent pathways Am. J. Physiol. 290 2006 G451 G457
26. M. Lazzeri, M.G. Vannucchi, M. Spinelli, E. Bizzoco, P. Beneforti, D. Turini, and M.S. Faussone-Pellegrini Transient receptor potential vanilloid type 1 (TRPV1) expression changes from normal urothelium to transitional cell carcinoma of human bladder Eur. Urol. 48 2005 691 698
27. M. Lazzeri, M.G. Vannucchi, C. Zardo, M. Spinelli, P. Beneforti, D. Turini, and M.S. Faussone-Pellegrini Immunohistochemical evidence of vanilloid receptor 1 in normal human urinary bladder Eur. Urol. 46 2004 792 798
28. Q. Lei, and A.P. Malykhina Colonic inflammation up-regulates voltage-gated sodium channels in bladder sensory neurons via activation of peripheral transient potential vanilloid 1 receptors Neurogastroenterol. Motil. 24 2012 575 e257
29. M. Li, Y. Sun, J.M. Simard, and T.C. Chai Increased transient receptor potential vanilloid type 1 (TRPV1) signaling in idiopathic overactive bladder urothelial cells Neurourol. Urodyn. 30 2011 606 611
30. A.P. Malykhina Neural mechanisms of pelvic organ cross-sensitization Neuroscience 149 2007 660 672
31. A.P. Malykhina, C. Qin, M.B. Greenwood-van, R.D. Foreman, F. Lupu, and H.I. Akbarali Hyperexcitability of convergent colon and bladder dorsal root ganglion neurons after colonic inflammation: mechanism for pelvic organ cross-talk Neurogastroenterol. Motil. 18 2006 936 948
32. T.J. Ness, and G.F. Gebhart Characterization of neurons responsive to noxious colorectal distension in the T13-L2 spinal cord of the rat J. Neurophysiol. 60 1988 1419 1438
33. T.J. Ness, and G.F. Gebhart Interactions between visceral and cutaneous nociception in the rat. II. Noxious visceral stimuli inhibit cutaneous nociceptive neurons and reflexes J. Neurophysiol. 66 1991 29 39
34. T.J. Ness, and G.F. Gebhart Interactions between visceral and cutaneous nociception in the rat. I. Noxious cutaneous stimuli inhibit visceral nociceptive neurons and reflexes J. Neurophysiol. 66 1991 20 28
35. R. Noronha, H. Akbarali, A. Malykhina, R.D. Foreman, and M.B. Greenwood-van Changes in urinary bladder smooth muscle function in response to colonic inflammation Am. J. Physiol. 293 2007 F1461 F1467
36. X.Q. Pan, J.A. Gonzalez, S. Chang, S. Chacko, A.J. Wein, and A.P. Malykhina Experimental colitis triggers the release of substance P and calcitonin gene-related peptide in the urinary bladder via TRPV1 signaling pathways Exp. Neurol. 225 2010 262 273
37. C.K. Payne, P.G. Mosbaugh, J.B. Forrest, R.J. Evans, K.E. Whitmore, J.P. Antoci, R. Perez-Marrero, K. Jacoby, A.C. Diokno, K.J. O'Reilly, T.L. Griebling, S.P. Vasavada, A.S. Yu, and L.R. Frumkin Intravesical resiniferatoxin for the treatment of interstitial cystitis: a randomized, double-blind, placebo controlled trial J. Urol. 173 2005 1590 1594
38. M.A. Pezzone, R. Liang, and M.O. Fraser A model of neural cross-talk and irritation in the pelvis: implications for the overlap of chronic pelvic pain disorders Gastroenterology 128 2005 1953 1964
39. C. Qin, A.P. Malykhina, H.I. Akbarali, and R.D. Foreman Cross-organ sensitization of lumbosacral spinal neurons receiving urinary bladder input in rats with inflamed colon Gastroenterology 129 2005 1967 1978
40. A. Szallasi, B. Conte, C. Goso, P.M. Blumberg, and S. Manzini Characterization of a peripheral vanilloid (capsaicin) receptor in the urinary bladder of the rat Life Sci. 52 1993 L221 L226
41. E.E. Ustinova, M.O. Fraser, and M.A. Pezzone Colonic irritation in the rat sensitizes urinary bladder afferents to mechanical and chemical stimuli: an afferent origin of pelvic organ cross-sensitization Am. J. Physiol. 290 2006 F1478 F1487
42. U. Wesselmann, P.P. Czakanski, G. Affaitati, and M.A. Giamberardino Uterine inflammation as a noxious visceral stimulus: behavioral characterization in the rat Neurosci. Lett. 246 1998 73 76
43. G.Y. Wong, and N.R. Gavva Therapeutic potential of vanilloid receptor TRPV1 agonists and antagonists as analgesics: recent advances and setbacks Brain Res. Rev. 60 2009 267 277
44. C.M. Xia, M.A. Gulick, S.J. Yu, J.R. Grider, K.S. Murthy, J.F. Kuemmerle, H.I. Akbarali, and L.Y. Qiao Up-regulation of brain-derived neurotrophic factor in primary afferent pathway regulates colon-to-bladder cross-sensitization in rat J. Neuroinflammation 9 2012 30
45. X. Xu, E. Gordon, Z. Lin, I.M. Lozinskaya, Y. Chen, and K.S. Thorneloe Functional TRPV4 channels and an absence of capsaicin-evoked currents in freshly-isolated, guinea-pig urothelial cells Channels (Austin) 3 2009 156 160
46. T. Yamada, S. Ugawa, T. Ueda, Y. Ishida, K. Kajita, and S. Shimada Differential localizations of the transient receptor potential channels TRPV4 and TRPV1 in the mouse urinary bladder J. Histochem. Cytochem. 57 2009 277 287
47. W. Yu, and W.G. Hill Defining protein expression in the urothelium: a problem of more than transitional interest Am. J. Physiol. 301 2011 F932 F942
48. W. Yu, W.G. Hill, G. Apodaca, and M.L. Zeidel Expression and distribution of transient receptor potential (TRP) channels in bladder epithelium Am. J. Physiol. 300 2011 F49 F59