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Volumn 23, Issue 4, 2014, Pages 463-473

Incidental findings from clinical genome-wide sequencing: A review

Author keywords

Clinical genetics; Genetic counseling; Genomic medicine; Incidental finding; Personalized medicine; Return of results; Secondary finding; Sequencing; Whole exome sequencing; Whole genome sequencing

Indexed keywords

HUMAN; HUMAN GENOME; INCIDENTAL FINDING; SEQUENCE ANALYSIS;

EID: 84904252658     PISSN: 10597700     EISSN: 15733599     Source Type: Journal    
DOI: 10.1007/s10897-013-9604-4     Document Type: Review
Times cited : (38)

References (100)
  • 1
    • 70350448684 scopus 로고    scopus 로고
    • Whole genome scanning: Resolving clinical diagnosis and management amidst complex data
    • 1:CAS:528:DC%2BD1MXhtFamsrbM 19531980 10.1203/PDR.0b013e3181b0cbd8
    • Ali-Khan, S. E.; Daar, A. S.; Shuman, C.; Ray, P. N.; Scherer, S. W. (2009). Whole genome scanning: resolving clinical diagnosis and management amidst complex data. Pediatric Research, 66, 357-363.
    • (2009) Pediatric Research , vol.66 , pp. 357-363
    • Ali-Khan, S.E.1    Daar, A.S.2    Shuman, C.3    Ray, P.N.4    Scherer, S.W.5
  • 2
    • 77951589703 scopus 로고    scopus 로고
    • Clinical assessment incorporating a personal genome
    • 1:CAS:528:DC%2BC3cXlsVOnt74%3D 2937184 20435227 10.1016/S0140-6736(10) 60452-7
    • Ashley, E. A.; Butte, A. J.; Wheeler, M. T.; Chen, R.; Klein, T. E.; Dewey, F. E.; et al. (2010). Clinical assessment incorporating a personal genome. Lancet, 375, 1525-1535.
    • (2010) Lancet , vol.375 , pp. 1525-1535
    • Ashley, E.A.1    Butte, A.J.2    Wheeler, M.T.3    Chen, R.4    Klein, T.E.5    Dewey, F.E.6
  • 3
    • 81255128009 scopus 로고    scopus 로고
    • Pediatric research and the return of individual research results
    • 10.1111/j.1748-720X.2011.00626.x
    • Avard, D.; Senecal, K.; Madadi, P.; Sinnett, D. (2011). Pediatric research and the return of individual research results. The Journal of Law, Medicine & Ethics, 39, 593-604.
    • (2011) The Journal of Law, Medicine & Ethics , vol.39 , pp. 593-604
    • Avard, D.1    Senecal, K.2    Madadi, P.3    Sinnett, D.4
  • 4
    • 84884587533 scopus 로고    scopus 로고
    • Informed consent for whole-genome sequencing studies in the clinical setting. Proposed recommendations on essential content and process
    • [Epub ahead of print]
    • Ayuso, C.; Millan, J.M.; Mancheno, M.; Dal-Re, R. (2013). Informed consent for whole-genome sequencing studies in the clinical setting. proposed recommendations on essential content and process. European Journal of Human Genetics [Epub ahead of print].
    • (2013) European Journal of Human Genetics
    • Ayuso, C.1    Millan, J.M.2    Mancheno, M.3    Dal-Re, R.4
  • 5
  • 6
    • 79959276553 scopus 로고    scopus 로고
    • Deploying whole genome sequencing in clinical practice and public health: Meeting the challenge one bin at a time
    • 21558861 10.1097/GIM.0b013e318220aaba
    • Berg, J. S.; Khoury, M. J.; Evans, J. P. (2011). Deploying whole genome sequencing in clinical practice and public health: meeting the challenge one bin at a time. Genetics in Medicine, 13, 499-504.
    • (2011) Genetics in Medicine , vol.13 , pp. 499-504
    • Berg, J.S.1    Khoury, M.J.2    Evans, J.P.3
  • 7
    • 84867724867 scopus 로고    scopus 로고
    • An informatics approach to analyzing the incidentalome
    • 3538953 22995991 10.1038/gim.2012.112
    • Berg, J. S.; Adams, M.; Nassar, N.; Bizon, C.; Lee, K.; Schmitt, C. P.; et al. (2012). An informatics approach to analyzing the incidentalome. Genetics in Medicine, 15, 36-44.
    • (2012) Genetics in Medicine , vol.15 , pp. 36-44
    • Berg, J.S.1    Adams, M.2    Nassar, N.3    Bizon, C.4    Lee, K.5    Schmitt, C.P.6
  • 8
    • 84869448616 scopus 로고    scopus 로고
    • Critical social theory approach to disclosure of genomic incidental findings
    • 22562957 10.1177/0969733011433924
    • Bevan, J. L.; Senn-Reeves, J. N.; Inventor, B. R.; Greiner, S. M.; Mayer, K. M.; Rivard, M. T.; et al. (2012). Critical social theory approach to disclosure of genomic incidental findings. Nursing Ethics, 19, 819-828.
    • (2012) Nursing Ethics , vol.19 , pp. 819-828
    • Bevan, J.L.1    Senn-Reeves, J.N.2    Inventor, B.R.3    Greiner, S.M.4    Mayer, K.M.5    Rivard, M.T.6
  • 9
    • 77957242301 scopus 로고    scopus 로고
    • Consumer perceptions of direct-to-consumer personalized genomic risk assessments
    • 20717041 10.1097/GIM.0b013e3181eb51c6
    • Bloss, C. S.; Ornowski, L.; Silver, E.; Cargill, M.; Vanier, V.; Schork, N. J.; et al. (2010). Consumer perceptions of direct-to-consumer personalized genomic risk assessments. Genetics in Medicine, 12, 556-566.
    • (2010) Genetics in Medicine , vol.12 , pp. 556-566
    • Bloss, C.S.1    Ornowski, L.2    Silver, E.3    Cargill, M.4    Vanier, V.5    Schork, N.J.6
  • 10
    • 84859608971 scopus 로고    scopus 로고
    • Public preferences regarding the return of individual genetic research results: Findings from a qualitative focus group study
    • 3927946 22402755 10.1038/gim.2011.66
    • Bollinger, J. M.; Scott, J.; Dvoskin, R.; Kaufman, D. (2012). Public preferences regarding the return of individual genetic research results: findings from a qualitative focus group study. Genetics in Medicine, 14, 451-457.
    • (2012) Genetics in Medicine , vol.14 , pp. 451-457
    • Bollinger, J.M.1    Scott, J.2    Dvoskin, R.3    Kaufman, D.4
  • 11
    • 33646254125 scopus 로고    scopus 로고
    • Reporting genetic results in research studies: Summary and recommendations of an NHLBI working group
    • NHLBI Working Group et al. 2556074 16575896 10.1002/ajmg.a.31195
    • Bookman, E. B.; Langehorne, A. A.; Eckfeldt, J. H.; Glass, K. C.; Jarvik, G. P.; Klag, M.; NHLBI Working Group, et al. (2006). Reporting genetic results in research studies: summary and recommendations of an NHLBI working group. American Journal of Medical Genetics. Part A, 140, 1033-1040.
    • (2006) American Journal of Medical Genetics. Part A , vol.140 , pp. 1033-1040
    • Bookman, E.B.1    Langehorne, A.A.2    Eckfeldt, J.H.3    Glass, K.C.4    Jarvik, G.P.5    Klag, M.6
  • 12
    • 33749473075 scopus 로고    scopus 로고
    • Presymptomatic and predictive genetic testing in minors: A systematic review of guidelines and position papers
    • 1:STN:280:DC%2BD28rpsFCgtQ%3D%3D 17026616 10.1111/j.1399-0004.2006.00692. x
    • Borry, P.; Stultiens, L.; Nys, H.; Cassiman, J. J.; Dierickx, K. (2006). Presymptomatic and predictive genetic testing in minors: a systematic review of guidelines and position papers. Clinical Genetics, 70, 374-381.
    • (2006) Clinical Genetics , vol.70 , pp. 374-381
    • Borry, P.1    Stultiens, L.2    Nys, H.3    Cassiman, J.J.4    Dierickx, K.5
  • 14
    • 79151476271 scopus 로고    scopus 로고
    • Disclosure of individual genetic data to research participants: The debate reconsidered
    • 1:CAS:528:DC%2BC3MXhtlams78%3D 21190750 10.1016/j.tig.2010.11.004
    • Bredenoord, A. L.; Kroes, H. Y.; Cuppen, E.; Parker, M.; van Delden, J. J. (2011). Disclosure of individual genetic data to research participants: the debate reconsidered. Trends in Genetics, 27, 41-47.
    • (2011) Trends in Genetics , vol.27 , pp. 41-47
    • Bredenoord, A.L.1    Kroes, H.Y.2    Cuppen, E.3    Parker, M.4    Van Delden, J.J.5
  • 16
    • 41849095185 scopus 로고    scopus 로고
    • Research ethics recommendations for whole-genome research: Consensus statement
    • 2270329 18366258 10.1371/journal.pbio.0060073
    • Caulfield, T.; McGuire, A. L.; Cho, M.; Buchanan, J. A.; Burgess, M. M.; Danilczyk, U.; et al. (2008). Research ethics recommendations for whole-genome research: consensus statement. PLoS Biology, 6, e73.
    • (2008) PLoS Biology , vol.6 , pp. 73
    • Caulfield, T.1    McGuire, A.L.2    Cho, M.3    Buchanan, J.A.4    Burgess, M.M.5    Danilczyk, U.6
  • 17
    • 44949095629 scopus 로고    scopus 로고
    • Understanding incidental findings in the context of genetics and genomics
    • 10.1111/j.1748-720X.2008.00270.x
    • Cho, M. K. (2008). Understanding incidental findings in the context of genetics and genomics. The Journal of Law, Medicine & Ethics, 36, 280-285.
    • (2008) The Journal of Law, Medicine & Ethics , vol.36 , pp. 280-285
    • Cho, M.K.1
  • 18
    • 84874109945 scopus 로고    scopus 로고
    • To tell or not to tell? A systematic review of ethical reflections on incidental findings arising in genetics contexts
    • 3573190 22739341 10.1038/ejhg.2012.130
    • Christenhusz, G. M.; Devriendt, K.; Dierickx, K. (2013). To tell or not to tell? A systematic review of ethical reflections on incidental findings arising in genetics contexts. European Journal of Human Genetics, 21, 248-55.
    • (2013) European Journal of Human Genetics , vol.21 , pp. 248-255
    • Christenhusz, G.M.1    Devriendt, K.2    Dierickx, K.3
  • 19
    • 44949128231 scopus 로고    scopus 로고
    • Incidental findings in genetics research using archived DNA
    • Clayton, E. W. (2008). Incidental findings in genetics research using archived DNA. The Journal of Law, Medicine & Ethics, 36, 286-291.
    • (2008) The Journal of Law, Medicine & Ethics , vol.36 , pp. 286-291
    • Clayton, E.W.1
  • 20
    • 0031087198 scopus 로고    scopus 로고
    • Genetic dilemmas and the child's right to an open future
    • 1:STN:280:DyaK2s3nvVSisA%3D%3D 9131346 10.2307/3527620
    • Davis, D. S. (1997). Genetic dilemmas and the child's right to an open future. The Hastings Center Report, 27, 7-15.
    • (1997) The Hastings Center Report , vol.27 , pp. 7-15
    • Davis, D.S.1
  • 21
    • 84862685273 scopus 로고    scopus 로고
    • A personal perspective on returning secondary results of clinical genome sequencing
    • 3698529 22734695 10.1186/gm353
    • Dimmock, D. (2012). A personal perspective on returning secondary results of clinical genome sequencing. Genome Medicine, 4, 54.
    • (2012) Genome Medicine , vol.4 , pp. 54
    • Dimmock, D.1
  • 22
    • 84870837938 scopus 로고    scopus 로고
    • Genetics specialists' perspectives on disclosure of genomic incidental findings in the clinical setting
    • 3522795 23068909 10.1016/j.pec.2012.09.010
    • Downing, N. R.; Williams, J. K.; Daack-Hirsch, S.; Driessnack, M.; Simon, C. M. (2013). Genetics specialists' perspectives on disclosure of genomic incidental findings in the clinical setting. Patient Education and Counseling, 90, 133-138.
    • (2013) Patient Education and Counseling , vol.90 , pp. 133-138
    • Downing, N.R.1    Williams, J.K.2    Daack-Hirsch, S.3    Driessnack, M.4    Simon, C.M.5
  • 23
    • 79952183410 scopus 로고    scopus 로고
    • The advent of personal genome sequencing
    • 21311341 10.1097/GIM.0b013e31820f16e6
    • Drmanac, R. (2011). The advent of personal genome sequencing. Genetics in Medicine, 13, 188-190.
    • (2011) Genetics in Medicine , vol.13 , pp. 188-190
    • Drmanac, R.1
  • 24
    • 84859610203 scopus 로고    scopus 로고
    • Return of results: Not that complicated?
    • 22481183 10.1038/gim.2012.8
    • Evans, J. P.; Rothschild, B. B. (2012). Return of results: not that complicated? Genetics in Medicine, 14, 358-360.
    • (2012) Genetics in Medicine , vol.14 , pp. 358-360
    • Evans, J.P.1    Rothschild, B.B.2
  • 25
    • 81555203460 scopus 로고    scopus 로고
    • Motivators for participation in a whole-genome sequencing study: Implications for translational genomics research
    • 1:CAS:528:DC%2BC3MXhsV2gsLrN 3230362 21731059 10.1038/ejhg.2011.123
    • Facio, F. M.; Brooks, S.; Loewenstein, J.; Green, S.; Biesecker, L. G.; Biesecker, B. B. (2011). Motivators for participation in a whole-genome sequencing study: Implications for translational genomics research. European Journal of Human Genetics, 19, 1213-1217.
    • (2011) European Journal of Human Genetics , vol.19 , pp. 1213-1217
    • Facio, F.M.1    Brooks, S.2    Loewenstein, J.3    Green, S.4    Biesecker, L.G.5    Biesecker, B.B.6
  • 26
    • 84877275931 scopus 로고    scopus 로고
    • Attitudes of canadian researchers toward the return to participants of incidental and targeted genomic findings obtained in a pediatric research setting
    • [Epub ahead of print]
    • Fernandez CV, Strahlendorf C, Avard D, Knoppers BM, O'Connell C, Bouffet E et al. 2013. Attitudes of canadian researchers toward the return to participants of incidental and targeted genomic findings obtained in a pediatric research setting. Medical Genetics [Epub ahead of print].
    • (2013) Medical Genetics
    • Fernandez, C.V.1    Strahlendorf, C.2    Avard, D.3    Knoppers, B.M.4    O'Connell, C.5    Bouffet, E.6
  • 27
    • 69549083158 scopus 로고    scopus 로고
    • Evaluating the utility of personal genomic information
    • 19478683 10.1097/GIM.0b013e3181a2743e
    • Foster, M. W.; Mulvihill, J. J.; Sharp, R. R. (2009). Evaluating the utility of personal genomic information. Genetics in Medicine, 11, 570-574.
    • (2009) Genetics in Medicine , vol.11 , pp. 570-574
    • Foster, M.W.1    Mulvihill, J.J.2    Sharp, R.R.3
  • 28
    • 84864117796 scopus 로고    scopus 로고
    • Direct-to-consumer genomic testing: Systematic review of the literature on user perspectives
    • 3400732 22333900 10.1038/ejhg.2012.18
    • Goldsmith, L.; Jackson, L.; O'Connor, A.; Skirton, H. (2012). Direct-to-consumer genomic testing: Systematic review of the literature on user perspectives. European Journal of Human Genetics, 20, 811-816.
    • (2012) European Journal of Human Genetics , vol.20 , pp. 811-816
    • Goldsmith, L.1    Jackson, L.2    O'Connor, A.3    Skirton, H.4
  • 29
    • 80053557894 scopus 로고    scopus 로고
    • Human genome sequencing in health and disease
    • 1:CAS:528:DC%2BC38XisleksL8%3D 3656720 22248320 10.1146/annurev-med- 051010-162644
    • Gonzaga-Jauregui, C.; Lupski, J. R.; Gibbs, R. A. (2012). Human genome sequencing in health and disease. Annual Review of Medicine, 63, 35-61.
    • (2012) Annual Review of Medicine , vol.63 , pp. 35-61
    • Gonzaga-Jauregui, C.1    Lupski, J.R.2    Gibbs, R.A.3
  • 30
    • 3242763836 scopus 로고    scopus 로고
    • Effect of a computer-based decision aid on knowledge, perceptions, and intentions about genetic testing for breast cancer susceptibility: A randomized controlled trial
    • 1:CAS:528:DC%2BD2cXmtFOmsrk%3D 1237120 15280342 10.1001/jama.292.4.442
    • Green, M. J.; Peterson, S. K.; Baker, M. W.; Harper, G. R.; Friedman, L. C.; Rubinstein, W. S.; et al. (2004). Effect of a computer-based decision aid on knowledge, perceptions, and intentions about genetic testing for breast cancer susceptibility: a randomized controlled trial. JAMA, 292, 442-452.
    • (2004) JAMA , vol.292 , pp. 442-452
    • Green, M.J.1    Peterson, S.K.2    Baker, M.W.3    Harper, G.R.4    Friedman, L.C.5    Rubinstein, W.S.6
  • 31
    • 18344379887 scopus 로고    scopus 로고
    • Use of an educational computer program before genetic counseling for breast cancer susceptibility: Effects on duration and content of counseling sessions
    • 1201432 15834239 10.1097/01.GIM.0000159905.13125.86
    • Green, M. J.; Peterson, S. K.; Baker, M. W.; Friedman, L. C.; Harper, G. R.; Rubinstein, W. S.; et al. (2005). Use of an educational computer program before genetic counseling for breast cancer susceptibility: Effects on duration and content of counseling sessions. Genetics in Medicine, 7, 221-229.
    • (2005) Genetics in Medicine , vol.7 , pp. 221-229
    • Green, M.J.1    Peterson, S.K.2    Baker, M.W.3    Friedman, L.C.4    Harper, G.R.5    Rubinstein, W.S.6
  • 32
    • 84859577332 scopus 로고    scopus 로고
    • Exploring concordance and discordance for return of incidental findings from clinical sequencing
    • 1:CAS:528:DC%2BC38Xlt1WmtLo%3D 3763716 22422049 10.1038/gim.2012.21
    • Green, R. C.; Berg, J. S.; Berry, G. T.; Biesecker, L. G.; Dimmock, D. P.; Evans, J. P.; et al. (2012). Exploring concordance and discordance for return of incidental findings from clinical sequencing. Genetics in Medicine, 14, 405-410.
    • (2012) Genetics in Medicine , vol.14 , pp. 405-410
    • Green, R.C.1    Berg, J.S.2    Berry, G.T.3    Biesecker, L.G.4    Dimmock, D.P.5    Evans, J.P.6
  • 34
    • 69549110336 scopus 로고    scopus 로고
    • Personal utility and genomic information: Look before you leap
    • 3417335 19623080 10.1097/GIM.0b013e3181af0a80
    • Grosse, S. D.; McBride, C. M.; Evans, J. P.; Khoury, M. J. (2009). Personal utility and genomic information: look before you leap. Genetics in Medicine, 11, 575-576.
    • (2009) Genetics in Medicine , vol.11 , pp. 575-576
    • Grosse, S.D.1    McBride, C.M.2    Evans, J.P.3    Khoury, M.J.4
  • 35
    • 80051791347 scopus 로고    scopus 로고
    • Public attitudes toward ancillary information revealed by pharmacogenetic testing under limited information conditions
    • 3150617 21633294 10.1097/GIM.0b013e31821afcc0
    • Haga, S. B.; O'daniel, J. M.; Tindall, G. M.; Lipkus, I. R.; Agans, R. (2011). Public attitudes toward ancillary information revealed by pharmacogenetic testing under limited information conditions. Genetics in Medicine, 13, 723-728.
    • (2011) Genetics in Medicine , vol.13 , pp. 723-728
    • Haga, S.B.1    O'Daniel, J.M.2    Tindall, G.M.3    Lipkus, I.R.4    Agans, R.5
  • 36
    • 84861848446 scopus 로고    scopus 로고
    • Incidental findings of therapeutic misconception in biobank-based research
    • 22261760 10.1038/gim.2011.50
    • Halverson, C. M.; Ross, L. F. (2012). Incidental findings of therapeutic misconception in biobank-based research. Genetics in Medicine, 14, 611-615.
    • (2012) Genetics in Medicine , vol.14 , pp. 611-615
    • Halverson, C.M.1    Ross, L.F.2
  • 37
    • 84857856437 scopus 로고    scopus 로고
    • The beliefs, motivations, and expectations of parents who have enrolled their children in a genetic biorepository
    • 3763713 22241099 10.1038/gim.2011.25
    • Harris, E. D.; Ziniel, S. I.; Amatruda, J. G.; Clinton, C. M.; Savage, S. K.; Taylor, P. L.; et al. (2012). The beliefs, motivations, and expectations of parents who have enrolled their children in a genetic biorepository. Genetics in Medicine, 14, 330-337.
    • (2012) Genetics in Medicine , vol.14 , pp. 330-337
    • Harris, E.D.1    Ziniel, S.I.2    Amatruda, J.G.3    Clinton, C.M.4    Savage, S.K.5    Taylor, P.L.6
  • 38
    • 36949010372 scopus 로고    scopus 로고
    • Familial adenomatous polyposis in a patient with unexplained mental retardation
    • 18046442 10.1038/ncpneuro0658
    • Heald, B.; Moran, R.; Milas, M.; Burke, C.; Eng, C. (2007). Familial adenomatous polyposis in a patient with unexplained mental retardation. Nature Clinical Practice Neurology, 3, 694-700.
    • (2007) Nature Clinical Practice Neurology , vol.3 , pp. 694-700
    • Heald, B.1    Moran, R.2    Milas, M.3    Burke, C.4    Eng, C.5
  • 40
    • 5644273777 scopus 로고    scopus 로고
    • Public experiences, knowledge and expectations about medical genetics and the use of genetic information
    • 15475669 10.1159/000080302
    • Henneman, L.; Timmermans, D. R.; van der Wal, G. (2004). Public experiences, knowledge and expectations about medical genetics and the use of genetic information. Community Genetics, 7, 33-43.
    • (2004) Community Genetics , vol.7 , pp. 33-43
    • Henneman, L.1    Timmermans, D.R.2    Van Der Wal, G.3
  • 41
    • 79951774156 scopus 로고    scopus 로고
    • The return of individual research findings in paediatric genetic research
    • 21059631 10.1136/jme.2010.037473
    • Hens, K.; Nys, H.; Cassiman, J. J.; Dierickx, K. (2011). The return of individual research findings in paediatric genetic research. Journal of Medical Ethics, 37, 179-183.
    • (2011) Journal of Medical Ethics , vol.37 , pp. 179-183
    • Hens, K.1    Nys, H.2    Cassiman, J.J.3    Dierickx, K.4
  • 43
    • 84873057028 scopus 로고    scopus 로고
    • Unintended diagnosis of von hippel lindau syndrome using array comparative genomic hybridization (CGH): Counseling challenges arising from unexpected information
    • 22895882 10.1007/s10897-012-9520-z
    • Hogan, J.; Turner, A.; Tucker, K.; Warwick, L. (2013). Unintended diagnosis of von hippel lindau syndrome using array comparative genomic hybridization (CGH): Counseling challenges arising from unexpected information. Journal of Genetic Counseling, 22, 22-26.
    • (2013) Journal of Genetic Counseling , vol.22 , pp. 22-26
    • Hogan, J.1    Turner, A.2    Tucker, K.3    Warwick, L.4
  • 44
    • 84870244597 scopus 로고    scopus 로고
    • Incidental findings in genetic research and clinical diagnostic tests: A systematic review
    • 10.1002/ajmg.a.35615
    • Jackson, L.; Goldsmith, L.; O'Connor, A.; Skirton, H. (2012). Incidental findings in genetic research and clinical diagnostic tests: a systematic review. American Journal of Medical Genetics. Part A, 12, 3159-3167.
    • (2012) American Journal of Medical Genetics. Part A , vol.12 , pp. 3159-3167
    • Jackson, L.1    Goldsmith, L.2    O'Connor, A.3    Skirton, H.4
  • 45
    • 84863986933 scopus 로고    scopus 로고
    • Secondary variants in individuals undergoing exome sequencing: Screening of 572 individuals identifies high-penetrance mutations in cancer-susceptibility genes
    • 1:CAS:528:DC%2BC38XovValtbY%3D 3397257 22703879 10.1016/j.ajhg.2012.05. 021
    • Johnston, J. J.; Rubinstein, W. S.; Facio, F. M.; Ng, D.; Singh, L. N.; Teer, J. K.; et al. (2012). Secondary variants in individuals undergoing exome sequencing: screening of 572 individuals identifies high-penetrance mutations in cancer-susceptibility genes. American Journal of Human Genetics, 91, 97-108.
    • (2012) American Journal of Human Genetics , vol.91 , pp. 97-108
    • Johnston, J.J.1    Rubinstein, W.S.2    Facio, F.M.3    Ng, D.4    Singh, L.N.5    Teer, J.K.6
  • 46
    • 77949653046 scopus 로고    scopus 로고
    • Ethical implications of the use of whole genome methods in medical research
    • 1:CAS:528:DC%2BC3cXjsFCrsrc%3D 2879322 19888293 10.1038/ejhg.2009.191
    • Kaye, J.; Boddington, P.; de Vries, J.; Hawkins, N.; Melham, K. (2010). Ethical implications of the use of whole genome methods in medical research. European Journal of Human Genetics, 18, 398-403.
    • (2010) European Journal of Human Genetics , vol.18 , pp. 398-403
    • Kaye, J.1    Boddington, P.2    De Vries, J.3    Hawkins, N.4    Melham, K.5
  • 47
    • 33750388916 scopus 로고    scopus 로고
    • The emergence of an ethical duty to disclose genetic research results: International perspectives
    • 16868560 10.1038/sj.ejhg.5201690
    • Knoppers, B. M.; Joly, Y.; Simard, J.; Durocher, F. (2006). The emergence of an ethical duty to disclose genetic research results: international perspectives. European Journal of Human Genetics, 14, 1170-1178.
    • (2006) European Journal of Human Genetics , vol.14 , pp. 1170-1178
    • Knoppers, B.M.1    Joly, Y.2    Simard, J.3    Durocher, F.4
  • 48
    • 77955610460 scopus 로고    scopus 로고
    • Multidimensional results reporting to participants in genomic studies: Getting it right
    • Kohane, I. S.; Taylor, P. L. (2010). Multidimensional results reporting to participants in genomic studies: getting it right. Science Translational Medicine, 2, 37-19.
    • (2010) Science Translational Medicine , vol.2 , pp. 37-19
    • Kohane, I.S.1    Taylor, P.L.2
  • 49
    • 33745905942 scopus 로고    scopus 로고
    • The incidentalome: A threat to genomic medicine
    • 1:CAS:528:DC%2BD28XmvFehs7w%3D 16835427 10.1001/jama.296.2.212
    • Kohane, I. S.; Masys, D. R.; Altman, R. B. (2006). The incidentalome: a threat to genomic medicine. JAMA, 296, 212-215.
    • (2006) JAMA , vol.296 , pp. 212-215
    • Kohane, I.S.1    Masys, D.R.2    Altman, R.B.3
  • 50
    • 34248647304 scopus 로고    scopus 로고
    • Medicine. Reestablishing the researcher-patient compact
    • 1:CAS:528:DC%2BD2sXlsFSgtLY%3D 17495156 10.1126/science.1135489
    • Kohane, I. S.; Mandl, K. D.; Taylor, P. L.; Holm, I. A.; Nigrin, D. J.; Kunkel, L. M. (2007). Medicine. reestablishing the researcher-patient compact. Science, 316, 836-837.
    • (2007) Science , vol.316 , pp. 836-837
    • Kohane, I.S.1    Mandl, K.D.2    Taylor, P.L.3    Holm, I.A.4    Nigrin, D.J.5    Kunkel, L.M.6
  • 51
    • 84859561085 scopus 로고    scopus 로고
    • Taxonomizing, sizing, and overcoming the incidentalome
    • Kohane, I. S.; Hsing, M.; Kong, S. W. (2012). Taxonomizing, sizing, and overcoming the incidentalome. Genetics in Medicine, 14, 399-404.
    • (2012) Genetics in Medicine , vol.14 , pp. 399-404
    • Kohane, I.S.1    Hsing, M.2    Kong, S.W.3
  • 53
    • 33750623548 scopus 로고    scopus 로고
    • Ethical considerations in the communication of unexpected information with clinical implications
    • 17085410 10.1080/15265160600938633
    • Lavieri, R. R.; Garner, S. A. (2006). Ethical considerations in the communication of unexpected information with clinical implications. The American Journal of Bioethics, 6, 46-48.
    • (2006) The American Journal of Bioethics , vol.6 , pp. 46-48
    • Lavieri, R.R.1    Garner, S.A.2
  • 54
    • 44949204698 scopus 로고    scopus 로고
    • Empirical analysis of current approaches to incidental findings
    • 10.1111/j.1748-720X.2008.00267.x
    • Lawrenz, F.; Sobotka, S. (2008). Empirical analysis of current approaches to incidental findings. The Journal of Law, Medicine & Ethics, 36, 249-255.
    • (2008) The Journal of Law, Medicine & Ethics , vol.36 , pp. 249-255
    • Lawrenz, F.1    Sobotka, S.2
  • 55
    • 84881613270 scopus 로고    scopus 로고
    • Perspectives of clinical genetics professionals toward genome sequencing and incidental findings: A survey study
    • [Epub ahead of print]
    • Lemke A, Bick D, Dimmock D, Simpson P, Veith R. 2012. Perspectives of clinical genetics professionals toward genome sequencing and incidental findings: a survey study. Clinical Genetics [Epub ahead of print].
    • (2012) Clinical Genetics
    • Lemke, A.1    Bick, D.2    Dimmock, D.3    Simpson, P.4    Veith, R.5
  • 56
    • 84898821625 scopus 로고    scopus 로고
    • An incidental finding of a large genomic deletion of BRCA1 on a molecular karyotype for a 5 year old child
    • 3326939 10.1186/1897-4287-10-S2-A73
    • Lewis, A.; James, P. (2012). An incidental finding of a large genomic deletion of BRCA1 on a molecular karyotype for a 5 year old child. Hereditary Cancer in Clinical Practice, 10(Suppl 2), A73.
    • (2012) Hereditary Cancer in Clinical Practice , vol.10 , Issue.SUPPL. 2 , pp. 73
    • Lewis, A.1    James, P.2
  • 57
    • 84874197574 scopus 로고    scopus 로고
    • Genetics professionals' perspectives on reporting incidental findings from clinical genome-wide sequencing
    • 10.1002/ajmg.a.35794
    • Lohn, Z.; Adam, S.; Birch, P. H.; Townsend, A.; Friedman, J. M. (2013). Genetics professionals' perspectives on reporting incidental findings from clinical genome-wide sequencing. American Journal of Medical Genetics, 161, 542-549.
    • (2013) American Journal of Medical Genetics , vol.161 , pp. 542-549
    • Lohn, Z.1    Adam, S.2    Birch, P.H.3    Townsend, A.4    Friedman, J.M.5
  • 58
    • 77950565347 scopus 로고    scopus 로고
    • Incidental findings in imaging diagnostic tests: A systematic review
    • 1:STN:280:DC%2BC3c3htVKjsQ%3D%3D 3473456 20335439 10.1259/bjr/98067945
    • Lumbreras, B.; Donat, L.; Hernandez-Aguado, I. (2010). Incidental findings in imaging diagnostic tests: a systematic review. British Journal of Radiology, 83, 276-289.
    • (2010) British Journal of Radiology , vol.83 , pp. 276-289
    • Lumbreras, B.1    Donat, L.2    Hernandez-Aguado, I.3
  • 59
    • 84862833585 scopus 로고    scopus 로고
    • Exome sequencing and unrelated findings in the context of complex disease research: Ethical and clinical implications
    • 3544941 21794208
    • Lyon, G. J.; Jiang, T.; Van Wijk, R.; Wang, W.; Bodily, P. M.; Xing, J.; et al. (2011). Exome sequencing and unrelated findings in the context of complex disease research: ethical and clinical implications. Discovery Medicine, 12, 41-55.
    • (2011) Discovery Medicine , vol.12 , pp. 41-55
    • Lyon, G.J.1    Jiang, T.2    Van Wijk, R.3    Wang, W.4    Bodily, P.M.5    Xing, J.6
  • 60
    • 84863116742 scopus 로고    scopus 로고
    • A systematic survey of loss-of-function variants in human protein-coding genes
    • 1:CAS:528:DC%2BC38XitFGqur0%3D 3299548 22344438 10.1126/science.1215040
    • MacArthur, D. G.; Balasubramanian, S.; Frankish, A.; Huang, N.; Morris, J.; Walter, K.; et al. (2012). A systematic survey of loss-of-function variants in human protein-coding genes. Science, 335, 823-828.
    • (2012) Science , vol.335 , pp. 823-828
    • Macarthur, D.G.1    Balasubramanian, S.2    Frankish, A.3    Huang, N.4    Morris, J.5    Walter, K.6
  • 61
    • 58149265800 scopus 로고    scopus 로고
    • Receiving inconclusive genetic test results: An interpretive description of the BRCA1/2 experience
    • 10.1002/nur.20286
    • Maheu, C.; Thorne, S. (2008). Receiving inconclusive genetic test results: an interpretive description of the BRCA1/2 experience. Research in Nursing & Health, 31, 553-562.
    • (2008) Research in Nursing & Health , vol.31 , pp. 553-562
    • Maheu, C.1    Thorne, S.2
  • 62
    • 77956204455 scopus 로고    scopus 로고
    • The concept analysis of therapeutic misconception
    • 20712237 10.7748/nr2010.07.17.4.83.c7927
    • Matutina, R. E. (2010). The concept analysis of therapeutic misconception. Nurse Researcher, 17, 83-90.
    • (2010) Nurse Researcher , vol.17 , pp. 83-90
    • Matutina, R.E.1
  • 64
    • 77951914791 scopus 로고    scopus 로고
    • Personal genome research: What should the participant be told?
    • 1:CAS:528:DC%2BC3cXltF2rsL8%3D 2868334 20381895 10.1016/j.tig.2009.12.007
    • McGuire, A. L.; Lupski, J. R. (2010). Personal genome research: what should the participant be told? Trends in Genetics, 26, 199-201.
    • (2010) Trends in Genetics , vol.26 , pp. 199-201
    • McGuire, A.L.1    Lupski, J.R.2
  • 65
    • 38549085235 scopus 로고    scopus 로고
    • Research ethics and the challenge of whole-genome sequencing
    • 1:CAS:528:DC%2BD1cXnt1ensg%3D%3D 2225443 18087293 10.1038/nrg2302
    • McGuire, A. L.; Caulfield, T.; Cho, M. K. (2008). Research ethics and the challenge of whole-genome sequencing. Nature Reviews Genetics, 9, 152-156.
    • (2008) Nature Reviews Genetics , vol.9 , pp. 152-156
    • McGuire, A.L.1    Caulfield, T.2    Cho, M.K.3
  • 67
    • 15444370705 scopus 로고    scopus 로고
    • General public's knowledge, interest and information needs related to genetic cancer: An exploratory study
    • 1:STN:280:DC%2BD2M%2FkvFOltQ%3D%3D 15677898 10.1097/00008469-200502000- 00010
    • Mesters, I.; Ausems, A.; De Vries, H. (2005). General public's knowledge, interest and information needs related to genetic cancer: an exploratory study. European Journal of Cancer Prevention, 14, 69-75.
    • (2005) European Journal of Cancer Prevention , vol.14 , pp. 69-75
    • Mesters, I.1    Ausems, A.2    De Vries, H.3
  • 69
    • 0042167542 scopus 로고    scopus 로고
    • Informed choice: Understanding knowledge in the context of screening uptake
    • 12900094 10.1016/S0738-3991(03)00044-2
    • Michie, S.; Dormandy, E.; Marteau, T. M. (2003). Informed choice: understanding knowledge in the context of screening uptake. Patient Education and Counseling, 50, 247-253.
    • (2003) Patient Education and Counseling , vol.50 , pp. 247-253
    • Michie, S.1    Dormandy, E.2    Marteau, T.M.3
  • 70
    • 72449160095 scopus 로고    scopus 로고
    • Clinical obligations and public health programmes: Healthcare provider reasoning about managing the incidental results of newborn screening
    • 1:STN:280:DC%2BD1MnlvFKgtw%3D%3D 19793944 10.1136/jme.2009.030346
    • Miller, F. A.; Hayeems, R. Z.; Bombard, Y.; Little, J.; Carroll, J. C.; Wilson, B.; et al. (2009). Clinical obligations and public health programmes: healthcare provider reasoning about managing the incidental results of newborn screening. Journal of Medical Ethics, 35, 626-634.
    • (2009) Journal of Medical Ethics , vol.35 , pp. 626-634
    • Miller, F.A.1    Hayeems, R.Z.2    Bombard, Y.3    Little, J.4    Carroll, J.C.5    Wilson, B.6
  • 71
    • 84864133229 scopus 로고    scopus 로고
    • One thing leads to another: The cascade of obligations when researchers report genetic research results to study participants
    • 3400736 22333903 10.1038/ejhg.2012.24
    • Miller, F. A.; Hayeems, R. Z.; Li, L.; Bytautas, J. P. (2012). One thing leads to another: the cascade of obligations when researchers report genetic research results to study participants. European Journal of Human Genetics, 20, 837-843.
    • (2012) European Journal of Human Genetics , vol.20 , pp. 837-843
    • Miller, F.A.1    Hayeems, R.Z.2    Li, L.3    Bytautas, J.P.4
  • 72
    • 58949100736 scopus 로고    scopus 로고
    • Australian study on public knowledge of human genetics and health
    • 1:STN:280:DC%2BD1cjotlGhsw%3D%3D 19039252 10.1159/000164684
    • Molster, C.; Charles, T.; Samanek, A.; O'Leary, P. (2009). Australian study on public knowledge of human genetics and health. Public Health Genomics, 12, 84-91.
    • (2009) Public Health Genomics , vol.12 , pp. 84-91
    • Molster, C.1    Charles, T.2    Samanek, A.3    O'Leary, P.4
  • 73
  • 74
    • 79951863517 scopus 로고    scopus 로고
    • Ethical and practical guidelines for reporting genetic research results to study participants: Updated guidelines from a national heart, lung, and blood institute working group
    • National Heart, Lung, and Blood Institute working group 3090664 21156933 10.1161/CIRCGENETICS.110.958827
    • National Heart, Lung, and Blood Institute working group, Fabsitz, R. R.; McGuire, A.; Sharp, R. R.; Puggal, M.; Beskow, L. M.; Biesecker, L. G.; et al. (2010). Ethical and practical guidelines for reporting genetic research results to study participants: updated guidelines from a national heart, lung, and blood institute working group. Circulation. Cardiovascular Genetics, 3, 574-580.
    • (2010) Circulation. Cardiovascular Genetics , vol.3 , pp. 574-580
    • Fabsitz, R.R.1    McGuire, A.2    Sharp, R.R.3    Puggal, M.4    Beskow, L.M.5    Biesecker, L.G.6
  • 75
    • 84864083351 scopus 로고    scopus 로고
    • Clinical application of exome sequencing in undiagnosed genetic conditions
    • 1:CAS:528:DC%2BC38Xht1Sht7fI 3375064 22581936 10.1136/jmedgenet-2012- 100819
    • Need, A. C.; Shashi, V.; Hitomi, Y.; Schoch, K.; Shianna, K. V.; McDonald, M. T.; et al. (2012). Clinical application of exome sequencing in undiagnosed genetic conditions. Journal of Medical Genetics, 49, 353-361.
    • (2012) Journal of Medical Genetics , vol.49 , pp. 353-361
    • Need, A.C.1    Shashi, V.2    Hitomi, Y.3    Schoch, K.4    Shianna, K.V.5    McDonald, M.T.6
  • 76
    • 67650508062 scopus 로고    scopus 로고
    • New challenges for informed consent through whole genome array testing
    • 1:CAS:528:DC%2BD1MXpslyjsrY%3D 19571117 10.1136/jmg.2009.068015
    • Netzer, C.; Klein, C.; Kohlhase, J.; Kubisch, C. (2009). New challenges for informed consent through whole genome array testing. Journal of Medical Genetics, 46, 495-496.
    • (2009) Journal of Medical Genetics , vol.46 , pp. 495-496
    • Netzer, C.1    Klein, C.2    Kohlhase, J.3    Kubisch, C.4
  • 77
    • 80053386108 scopus 로고    scopus 로고
    • Public perspectives on returning genetics and genomics research results
    • 3221258 21555865 10.1159/000324933
    • O'Daniel, J.; Haga, S. B. (2011). Public perspectives on returning genetics and genomics research results. Public Health Genomics, 14, 346-55.
    • (2011) Public Health Genomics , vol.14 , pp. 346-355
    • O'Daniel, J.1    Haga, S.B.2
  • 78
    • 84864585651 scopus 로고    scopus 로고
    • Whole-genome and whole-exome sequencing in hereditary cancer: Impact on genetic testing and counseling
    • 10.1097/PPO.0b013e318262467e
    • O'Daniel, J. M.; Lee, K. (2012). Whole-genome and whole-exome sequencing in hereditary cancer: impact on genetic testing and counseling. Cancer Journal, 18, 287-292.
    • (2012) Cancer Journal , vol.18 , pp. 287-292
    • O'Daniel, J.M.1    Lee, K.2
  • 80
    • 44949084673 scopus 로고    scopus 로고
    • The future of incidental findings: Should they be viewed as benefits?
    • 10.1111/j.1748-720X.2008.00278.x
    • Parker, L. S. (2008). The future of incidental findings: should they be viewed as benefits? The Journal of Law, Medicine & Ethics, 36, 341-351.
    • (2008) The Journal of Law, Medicine & Ethics , vol.36 , pp. 341-351
    • Parker, L.S.1
  • 81
    • 33750631748 scopus 로고    scopus 로고
    • Disclosing individual genetic results to research participants
    • 17085395 10.1080/15265160600934772
    • Ravitsky, V.; Wilfond, B. S. (2006). Disclosing individual genetic results to research participants. The American Journal of Bioethics, 6, 8-17.
    • (2006) The American Journal of Bioethics , vol.6 , pp. 8-17
    • Ravitsky, V.1    Wilfond, B.S.2
  • 82
    • 77956396559 scopus 로고    scopus 로고
    • Tailoring the process of informed consent in genetic and genomic research
    • 2873798 20346094 10.1186/gm141
    • Rotimi, C. N.; Marshall, P. A. (2010). Tailoring the process of informed consent in genetic and genomic research. Genome Medicine, 2, 20.
    • (2010) Genome Medicine , vol.2 , pp. 20
    • Rotimi, C.N.1    Marshall, P.A.2
  • 83
    • 66249144689 scopus 로고    scopus 로고
    • Predictive diagnosis of the cancer prone li-fraumeni syndrome by accident: New challenges through whole genome array testing
    • 1:CAS:528:DC%2BD1MXms1Khsb0%3D 2669880 19269943 10.1136/jmg.2008.064972
    • Schwarzbraun, T.; Obenauf, A. C.; Langmann, A.; Gruber-Sedlmayr, U.; Wagner, K.; Speicher, M. R.; et al. (2009). Predictive diagnosis of the cancer prone li-fraumeni syndrome by accident: new challenges through whole genome array testing. Journal of Medical Genetics, 46, 341-344.
    • (2009) Journal of Medical Genetics , vol.46 , pp. 341-344
    • Schwarzbraun, T.1    Obenauf, A.C.2    Langmann, A.3    Gruber-Sedlmayr, U.4    Wagner, K.5    Speicher, M.R.6
  • 84
    • 84879690625 scopus 로고    scopus 로고
    • "grasping the grey": Patient understanding and interpretation of an intermediate allele predictive test result for huntington disease
    • 1:STN:280:DC%2BC38fptFSjtw%3D%3D 22903792 10.1007/s10897-012-9533-7
    • Semaka, A.; Balneaves, L. G.; Hayden, M. R. (2013). "Grasping the grey": patient understanding and interpretation of an intermediate allele predictive test result for huntington disease. Journal of Genetic Counseling, 22, 200-17.
    • (2013) Journal of Genetic Counseling , vol.22 , pp. 200-217
    • Semaka, A.1    Balneaves, L.G.2    Hayden, M.R.3
  • 85
    • 79952185587 scopus 로고    scopus 로고
    • Downsizing genomic medicine: Approaching the ethical complexity of whole-genome sequencing by starting small
    • 21311340 10.1097/GIM.0b013e31820f603f
    • Sharp, R. R. (2011). Downsizing genomic medicine: approaching the ethical complexity of whole-genome sequencing by starting small. Genetics in Medicine, 13, 191-194.
    • (2011) Genetics in Medicine , vol.13 , pp. 191-194
    • Sharp, R.R.1
  • 86
    • 28244484901 scopus 로고    scopus 로고
    • When "minimal risk" research yields clinically-significant data, maybe the risks aren't so minimal
    • 15186687 10.1162/152651604323097970
    • Sharp, H. M.; Orr, R. D. (2004). When "minimal risk" research yields clinically-significant data, maybe the risks aren't so minimal. The American Journal of Bioethics, 4, W32-6.
    • (2004) The American Journal of Bioethics , vol.4 , pp. 32-36
    • Sharp, H.M.1    Orr, R.D.2
  • 89
    • 34548675362 scopus 로고    scopus 로고
    • Ethical implications of array comparative genomic hybridization in complex phenotypes: Points to consider in research
    • 2220022 17873651 10.1097/GIM.0b013e3181485688
    • Tabor, H. K.; Cho, M. K. (2007). Ethical implications of array comparative genomic hybridization in complex phenotypes: points to consider in research. Genetics in Medicine, 9, 626-631.
    • (2007) Genetics in Medicine , vol.9 , pp. 626-631
    • Tabor, H.K.1    Cho, M.K.2
  • 90
    • 84861225247 scopus 로고    scopus 로고
    • Informed consent for whole genome sequencing: A qualitative analysis of participant expectations and perceptions of risks, benefits, and harms
    • 3426313 22532433 10.1002/ajmg.a.35328
    • Tabor, H. K.; Stock, J.; Brazg, T.; McMillin, M. J.; Dent, K. M.; Yu, J. H.; et al. (2012). Informed consent for whole genome sequencing: a qualitative analysis of participant expectations and perceptions of risks, benefits, and harms. American Journal of Medical Genetics. Part A, 158A, 1310-1319.
    • (2012) American Journal of Medical Genetics. Part A , vol.158 , pp. 1310-1319
    • Tabor, H.K.1    Stock, J.2    Brazg, T.3    McMillin, M.J.4    Dent, K.M.5    Yu, J.H.6
  • 91
    • 70349260949 scopus 로고    scopus 로고
    • Parents' interest in predictive genetic testing for their children when a disease has no treatment
    • 10.1542/peds.2008-2389
    • Tarini, B. A.; Singer, D.; Clark, S. J.; Davis, M. M. (2009). Parents' interest in predictive genetic testing for their children when a disease has no treatment. Pediatrics, 124, 432-8.
    • (2009) Pediatrics , vol.124 , pp. 432-438
    • Tarini, B.A.1    Singer, D.2    Clark, S.J.3    Davis, M.M.4
  • 92
    • 84863556835 scopus 로고    scopus 로고
    • Evolution and functional impact of rare coding variation from deep sequencing of human exomes
    • 1:CAS:528:DC%2BC38XpsFKksrY%3D 3708544 22604720 10.1126/science.1219240
    • Tennessen, J. A.; Bigham, A. W.; O'Connor, T. D.; Fu, W.; Kenny, E. E.; Gravel, S.; et al. (2012). Evolution and functional impact of rare coding variation from deep sequencing of human exomes. Science, 337, 64-9.
    • (2012) Science , vol.337 , pp. 64-69
    • Tennessen, J.A.1    Bigham, A.W.2    O'Connor, T.D.3    Fu, W.4    Kenny, E.E.5    Gravel, S.6
  • 94
    • 84860584490 scopus 로고    scopus 로고
    • Whole-genome sequencing and the physician
    • 1:CAS:528:DC%2BC38XpvFCntLs%3D 22404433 10.1111/j.1399-0004.2012.01868.x
    • Thorogood, A.; Knoppers, B.; Dondorp, W.; de Wert, G. (2012). Whole-genome sequencing and the physician. Clinical Genetics, 81, 511-513.
    • (2012) Clinical Genetics , vol.81 , pp. 511-513
    • Thorogood, A.1    Knoppers, B.2    Dondorp, W.3    De Wert, G.4
  • 95
    • 84866491890 scopus 로고    scopus 로고
    • "i want to know what's in pandora's box": Comparing stakeholder perspectives on incidental findings in clinical whole genomic sequencing
    • 22903777 10.1002/ajmg.a.35554
    • Townsend, A.; Adam, S.; Birch, P. H.; Lohn, Z.; Rousseau, F.; Friedman, J. M. (2012). "I want to know what's in pandora's box": comparing stakeholder perspectives on incidental findings in clinical whole genomic sequencing. American Journal of Medical Genetics. Part A, 158A, 2519-2525.
    • (2012) American Journal of Medical Genetics. Part A , vol.158 , pp. 2519-2525
    • Townsend, A.1    Adam, S.2    Birch, P.H.3    Lohn, Z.4    Rousseau, F.5    Friedman, J.M.6
  • 96
  • 98
    • 44949123795 scopus 로고    scopus 로고
    • Introduction: The challenge of incidental findings
    • 10.1111/j.1748-720X.2008.00265.x
    • Wolf, S. M. (2008). Introduction: the challenge of incidental findings. The Journal of Law, Medicine & Ethics, 36, 216-218.
    • (2008) The Journal of Law, Medicine & Ethics , vol.36 , pp. 216-218
    • Wolf, S.M.1
  • 100
    • 84859566974 scopus 로고    scopus 로고
    • Managing incidental findings and research results in genomic research involving biobanks and archived data sets
    • 3597341 22436882 10.1038/gim.2012.23
    • Wolf, S. M.; Crock, B. N.; Van Ness, B.; Lawrenz, F.; Kahn, J. P.; Beskow, L. M.; et al. (2012). Managing incidental findings and research results in genomic research involving biobanks and archived data sets. Genetics in Medicine, 14, 361-384.
    • (2012) Genetics in Medicine , vol.14 , pp. 361-384
    • Wolf, S.M.1    Crock, B.N.2    Van Ness, B.3    Lawrenz, F.4    Kahn, J.P.5    Beskow, L.M.6


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