Evaluating the utility of personal genomic information

Genetics in Medicine

Volumn 11, Issue 8, 2009, Pages 570-574

  Foster, Morris W ^a,b   Mulvihill, John J ^b   Sharp, Richard R ^c  

^a UNIVERSITY OF OKLAHOMA   (United States)

^b UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

^c LERNER RESEARCH INSTITUTE   (United States)

Author keywords

Ethics; Genetic testing; Health awareness; Personalized medicine; Utility

Indexed keywords

AWARENESS; BEHAVIOR CHANGE; COST EFFECTIVENESS ANALYSIS; GENOME ANALYSIS; GENOMICS; HEALTH CARE PLANNING; HEALTH HAZARD; HUMAN; HUMAN GENOME; INFORMATION DISSEMINATION; LIFESTYLE MODIFICATION; MEDICAL DECISION MAKING; MEDICAL INFORMATION; NOTE;

GENETIC COUNSELING; GENETIC PREDISPOSITION TO DISEASE; GENOME, HUMAN; GENOMICS; HUMANS; INFORMATION DISSEMINATION; PERSONAL HEALTH SERVICES; RISK ASSESSMENT;

EID: 69549083158     PISSN: 10983600     EISSN: None     Source Type: Journal    
DOI: 10.1097/GIM.0b013e3181a2743e     Document Type: Note

References (31)

1. Khoury MJ, Yang QH, Gwinn M, et al. An epidemiologic assessment of genomic profiling for measuring susceptibility to common diseases and targeting interventions. Genet Med 2004;6:38-47. (Pubitemid 38175976)
2. Sanderson S, Zimmern R, Kroese M, et al. How can the evaluation of genetic tests be enhanced? Lessons learned from the ACCE framework and evaluating genetic tests in the United Kingdom. Genet Med 2005;7:495-500. (Pubitemid 41445490)
3. Mardis ER. The impact of next-generation sequencing technology on genetics. Trends Genet 2008;24:133-141.
4. Gniady JA. Regulating direct-to-consumer genetic testing: protecting the consumer without quashing a medical revolution. Fordham Law Rev 2008;76:2429-2475.
5. McCullen MA, Crawford DHG, Hickman PE. Screening for hemochromatosis. Clin Chim Acta 2002;315:169-186.
6. Loughrey MR, Waring PM, Tan A, et al. Incorporation of somatic BRAF mutation testing into an algorithm for the investigation of hereditary non-polyposis colorectal cancer. Fam Cancer 2007;6:301-310. (Pubitemid 47175009)
7. Berg AO, Piper M, Armstrong K, et al. Recommendations from the EGAPP Working Group: testing for cytochrome P450 polymorphisms in adults with nonpsychotic depression treated with selective serotonin reuptake inhibitors. Genet Med 2007;9:819-825. (Pubitemid 350295209)
8. Hunter DJ, Khoury MJ, Drazen JM. Letting the genome out of the bottle: will we get our wish? N Engl J Med 2008;358:105-107.
9. Broadstock M, Michie S, Marteau T. Psychological consequences of predictive genetic testing: a systematic review. Eur J Genet 2000;8:731-738. (Pubitemid 30767672)
10. Offit K, Biesecker BB, Burt RW, et al. Statement of the American Society of Clinical Oncology: genetic testing for cancer susceptibility. J Clin Oncol 1996;14:1730-1736. (Pubitemid 126425578)
11. Shirts BH, Parker LS. Changing interpretations, stable genes: responsibilities of patients, professionals, and policy makers in the clinical interpretation of complex genetic information. Genet Med 2008;10:278-283.
12. Grosse SD, Khoury MJ. What is the clinical utility of genetic testing? Genet Med 2006;8:448-450. (Pubitemid 44289007)
13. Tatsioni D, Zarin DA, Aronson N, et al. Challenges in systematic reviews of diagnostic technologies. Ann Intern Med 2005;142:1048-1055. (Pubitemid 40847707)
14. Foster MW, Sharp RR. The contractual genome: how direct-to-consumer genomic services may help patients take ownership of their DNA. Person Med 2008;5:399-404.
15. McCullough LB, Wilson NL, Teasdale TA, et al. Mapping personal, familial, and professional values in long-term-care decisions. Gerontologist 1993;33:324-332.
16. Denscombe M. Uncertain identities and health-risking behaviour: the case of young people and smoking in late modernity. Br J Sociol 2001;52:157-177. (Pubitemid 33597374)
17. Hays RD, Kravitz RL, Mazel RM, et al. The impact of patient adherence on health outcomes for patients with chronic disease in the medical outcomes study. J Behav Med 1994;17:347-360.
18. Ende J, Kazis L, Ash A, Moskowitz MA. Ware patient satisfaction questionnaire - short version. J Gen Int Med 1989;4:23-30.
19. Stein REK, Riessman CK. The development of an impact-on-family sale - preliminary findings. Med Care 1980;18:465-472.
20. Arn PH. Newborn screening: current status. Health Aff 2007;26:559-566.
21. Griffith GL, Edwards RT, Gray J. Cancer genetics services: a systematic review of the economic evidence and issues. Br J Cancer 2004;90:1697-1703. (Pubitemid 38725636)
22. Halbert CH, Lynch H, Lynch J, et al. Colon cancer screening practices following genetic testing for hereditary nonpolyposis colon cancer (HNPCC) mutations. Arch Intern Med 2004;164:1881-1887. (Pubitemid 39274358)
23. Sanderson SC, Wardle J. Will genetic testing for complex diseases increase motivation to quit smoking? Anticipated reactions in a survey of smokers. Health Educ Behav 2005;32:640-653. (Pubitemid 41426745)
24. Walter FM, Emery J, Braithwaite D, Marteau TM. Lay understanding of familial risk of common chronic diseases: a systematic review and synthesis of qualitative research. Ann Fam Med 2004;2:583-594. (Pubitemid 39643434)
25. Lerman C, Marshall J, Audrain J, et al. Genetic testing for colon cancer susceptibility: anticipated reactions of patients and challenges to providers. Int J Cancer 1996;69:58-61. (Pubitemid 26083274)
26. Foster MW, Sharp RR. Out of sequence: how consumer genomics could displace clinical genetics. Nat Rev Genet 2008;9:419.
27. Khoury MJ, Berg AO, Coates R, Evans J, Teutsch SM, Bradley LA. The evidence dilemma in genomic medicine: we need a roadmap for the appropriate integration of genomic discoveries into clinical practice. Health Aff 2008;27:1600-1611.
28. Howard HC, Borry P. Direct-to-consumer genetic testing: more questions than benefits? Person Med 2008;5:317-320.
29. Katsanis SH, Javitt G, Hudson K. A case study of personalized medicine. Science 2008;320:53-54.
30. Grosse SD, Wordsworth S, Payne K. Economic methods for valuing the outcomes of genetic testing: beyond cost-effectiveness analysis. Genet Med 2008;10:648-654.
31. Heshka JT, Palleschi C, Howley H, Wilson B, Wells PS. A systematic review of perceived risks, psychological and behavioral impacts of genetic testing. Genet Med 2008;10:19-32.