Celecoxib suppresses hepatoma stemness and progression by up-regulating PTEN

Oncotarget

Volumn 5, Issue 6, 2014, Pages 1475-1490

  Chu, Tian Huei ^a,g   Chan, Hoi Hung ^a,b,c,d,g   Kuo, Hsiao Mei ^e,g   Liu, Li Fen ^f,g   Hu, Tsung Hui ^e,g   Sun, Cheuk Kwan ^f,g   Kung, Mei Lang ^a,g   Lin, Shih Wei ^a,g   Wang, E Ming ^a,b,g   Ma, Yi Ling ^a,g   Cheng, Kwan Hung ^a,g   Lai, Kwok Hung ^b,c,g   Wen, Zhi Hong ^a,g   Hsu, Ping I ^b,c,g   Tai, Ming Hong ^a,g  

^a NATIONAL SUN YAT SEN UNIVERSITY   (Taiwan)

^b KAOHSIUNG VETERANS GENERAL HOSPITAL   (Taiwan)

^c NATIONAL YANG MING UNIVERSITY   (Taiwan)

^d TAJEN UNIVERSITY   (Taiwan)

^e CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^f I SHOU UNIVERSITY   (Taiwan)

^g E DA HOSPITAL   (Taiwan)

Author keywords

Celecoxib; Hepatic cancer stem cells; Hepatocellular carcinoma; Phosphatase and tensin homolog; Prostaglandin E2

Indexed keywords

CD133 ANTIGEN; CELECOXIB; HERMES ANTIGEN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROSTAGLANDIN E2; PROTEIN KINASE B; CD44 PROTEIN, HUMAN; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; MESSENGER RNA; PTEN PROTEIN, HUMAN; PTGS2 PROTEIN, RAT; PYRAZOLE DERIVATIVE; SULFONAMIDE;

ADENOVIRUS; ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN EXPRESSION; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CANCER STEM CELL; CELL DISRUPTION; CELL EXPANSION; CELL PROLIFERATION; CONTROLLED STUDY; DISEASE COURSE; DRUG EFFICACY; DRUG MECHANISM; ENZYME ACTIVATION; GENE TARGETING; HUMAN; HUMAN CELL; IMMUNOHISTOLOGY; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; NOVIKOFF HEPATOMA; PTEN GENE; RAT; SIGNAL TRANSDUCTION; SURVIVAL RATE; TUMOR VOLUME; UPREGULATION; ANIMAL; CARCINOMA, HEPATOCELLULAR; CHEMISTRY; DRUG EFFECTS; ENZYME IMMUNOASSAY; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; GENETICS; LIVER NEOPLASMS; MALE; METABOLISM; PATHOLOGY; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPRAGUE DAWLEY RAT; TRANSCRIPTION INITIATION; TUMOR CELL CULTURE; WESTERN BLOTTING;

ANIMALS; ANTIGENS, CD44; APOPTOSIS; BLOTTING, WESTERN; CARCINOMA, HEPATOCELLULAR; CELL PROLIFERATION; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; DINOPROSTONE; DISEASE PROGRESSION; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; IMMUNOENZYME TECHNIQUES; LIVER NEOPLASMS; MALE; NEOPLASTIC STEM CELLS; PPAR GAMMA; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; PYRAZOLES; RATS; RATS, SPRAGUE-DAWLEY; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION; SULFONAMIDES; TRANSCRIPTIONAL ACTIVATION; TUMOR CELLS, CULTURED; UP-REGULATION;

EID: 84904251607     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.1745     Document Type: Article

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