-
1
-
-
79959324452
-
MicroRNA dysregulation during chemical carcinogenesis
-
Pogribny IP: MicroRNA dysregulation during chemical carcinogenesis. Epigenomics 1: 281-290, 2009.
-
(2009)
Epigenomics
, vol.1
, pp. 281-290
-
-
Pogribny, I.P.1
-
2
-
-
74249114436
-
Recent proceedings in epigenetics research of lung cancer
-
(In Japanese)
-
Takai D: Recent proceedings in epigenetics research of lung cancer. Nihon Rinsho 67: 2387-2396, 2009 (In Japanese).
-
(2009)
Nihon Rinsho
, vol.67
, pp. 2387-2396
-
-
Takai, D.1
-
3
-
-
84863377480
-
MicroRNAs: Novel biomarkers for lung cancer diagnosis, prediction and treatment
-
Wang Q, Wang S, Wang H, Li P and Ma Z: MicroRNAs: novel biomarkers for lung cancer diagnosis, prediction and treatment. Exp Biol Med 237: 227-235, 2012.
-
(2012)
Exp Biol Med
, vol.237
, pp. 227-235
-
-
Wang, Q.1
Wang, S.2
Wang, H.3
Li, P.4
Ma, Z.5
-
4
-
-
84855382989
-
MicroRNA-99b acts as a tumor suppressor in non-small cell lung cancer by directly targeting fibroblast growth factor receptor 3
-
Kang J, Lee SY, Lee SY, et al: microRNA-99b acts as a tumor suppressor in non-small cell lung cancer by directly targeting fibroblast growth factor receptor 3. Exp Ther Med 3: 149-153, 2012.
-
(2012)
Exp Ther Med
, vol.3
, pp. 149-153
-
-
Kang, J.1
Lee, S.Y.2
Lee, S.Y.3
-
5
-
-
81255205360
-
Targeting of the tumor suppressor GRHL3 by a miR-21-dependent proto-oncogenic network results in PTEN loss and tumorigenesis
-
Darido C, Georgy SR, Wilanowski T, et al: Targeting of the tumor suppressor GRHL3 by a miR-21-dependent proto-oncogenic network results in PTEN loss and tumorigenesis. Cancer Cell 20: 635-648, 2011.
-
(2011)
Cancer Cell
, vol.20
, pp. 635-648
-
-
Darido, C.1
Georgy, S.R.2
Wilanowski, T.3
-
6
-
-
84860466755
-
MicroRNA profiling and prediction of recurrence/relapse-free survival in stage I lung cancer
-
Lu Y, Govindan R, Wang L, et al: MicroRNA profiling and prediction of recurrence/relapse-free survival in stage I lung cancer. Carcinogenesis 33: 1046-1054, 2012.
-
(2012)
Carcinogenesis
, vol.33
, pp. 1046-1054
-
-
Lu, Y.1
Govindan, R.2
Wang, L.3
-
7
-
-
78549269168
-
MiRNA-145 inhibits non-small cell lung cancer cell proliferation by targeting c-Myc
-
Chen Z, Zeng H, Guo Y, et al: miRNA-145 inhibits non-small cell lung cancer cell proliferation by targeting c-Myc. J Exp Clin Cancer Res 29: 151, 2010.
-
(2010)
J Exp Clin Cancer Res
, vol.29
, pp. 151
-
-
Chen, Z.1
Zeng, H.2
Guo, Y.3
-
8
-
-
77749320890
-
MicroRNA-145 targets YES and STAT1 in colon cancer cells
-
Gregersen LH, Jacobsen AB, Frankel LB, Wen J, Krogh A and Lund AH: MicroRNA-145 targets YES and STAT1 in colon cancer cells. PLoS One 5: e8836, 2010.
-
(2010)
PLoS One
, vol.5
-
-
Gregersen, L.H.1
Jacobsen, A.B.2
Frankel, L.B.3
Wen, J.4
Krogh, A.5
Lund, A.H.6
-
9
-
-
84861495556
-
Therapeutic targeting of the epidermal growth factor receptor in human cancer
-
Dhomen NS, Mariadason J, Tebbutt N and Scott AM: Therapeutic targeting of the epidermal growth factor receptor in human cancer. Crit Rev Oncog 17: 31-50, 2012.
-
(2012)
Crit Rev Oncog
, vol.17
, pp. 31-50
-
-
Dhomen, N.S.1
Mariadason, J.2
Tebbutt, N.3
Scott, A.M.4
-
10
-
-
84861042428
-
Primary and acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors in non-small cell lung cancer: An update
-
Ayoola A, Barochia A, Belani K and Belani CP: Primary and acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors in non-small cell lung cancer: an update. Cancer Invest 30: 433-446, 2012.
-
(2012)
Cancer Invest
, vol.30
, pp. 433-446
-
-
Ayoola, A.1
Barochia, A.2
Belani, K.3
Belani, C.P.4
-
11
-
-
82955162659
-
MicroRNAs involved in the EGFR/PTEN/AKT pathway in gliomas
-
Wang Y, Wang X, Zhang J, et al: MicroRNAs involved in the EGFR/PTEN/AKT pathway in gliomas. J Neurooncol 106: 217-224, 2012.
-
(2012)
J Neurooncol
, vol.106
, pp. 217-224
-
-
Wang, Y.1
Wang, X.2
Zhang, J.3
-
12
-
-
0030772168
-
Radiation-induced proliferation of the human A431 squamous carcinoma cells is dependent on EGFR tyrosine phosphorylation
-
Schmidt-Ullrich RK, Mikkelsen RB, Dent P, et al: Radiation-induced proliferation of the human A431 squamous carcinoma cells is dependent on EGFR tyrosine phosphorylation. Oncogene 15: 1191-1197, 1997.
-
(1997)
Oncogene
, vol.15
, pp. 1191-1197
-
-
Schmidt-Ullrich, R.K.1
Mikkelsen, R.B.2
Dent, P.3
-
13
-
-
33646044696
-
Preclinical analysis of the analinoquinazoline AG1478, a specific small molecule inhibitor of EGF receptor tyrosine kinase
-
Ellis AG, Doherty MM, Walker F, et al: Preclinical analysis of the analinoquinazoline AG1478, a specific small molecule inhibitor of EGF receptor tyrosine kinase. Biochem Pharmacol 71: 1422-1434, 2006.
-
(2006)
Biochem Pharmacol
, vol.71
, pp. 1422-1434
-
-
Ellis, A.G.1
Doherty, M.M.2
Walker, F.3
-
14
-
-
18244371651
-
Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain
-
Pao W, Miller VA, Politi KA, et al: Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain. PLoS Med 2: e73, 2005.
-
(2005)
PLoS Med
, vol.2
-
-
Pao, W.1
Miller, V.A.2
Politi, K.A.3
-
15
-
-
85047698100
-
Inhibition of constitutively active Stat3 suppresses growth of human ovarian and breast cancer cells
-
Burke WM, Jin X, Lin HJ, et al: Inhibition of constitutively active Stat3 suppresses growth of human ovarian and breast cancer cells. Oncogene 20: 7925-7934, 2001.
-
(2001)
Oncogene
, vol.20
, pp. 7925-7934
-
-
Burke, W.M.1
Jin, X.2
Lin, H.J.3
-
16
-
-
0037179847
-
Role of the phosphatidylinositol 3-kinase/Akt and mTOR/P70S6-kinase pathways in the proliferation and apoptosis in multiple myeloma
-
Pene F, Claessens YE, Muller O, et al: Role of the phosphatidylinositol 3-kinase/Akt and mTOR/P70S6-kinase pathways in the proliferation and apoptosis in multiple myeloma. Oncogene 21: 6587-6597, 2002.
-
(2002)
Oncogene
, vol.21
, pp. 6587-6597
-
-
Pene, F.1
Claessens, Y.E.2
Muller, O.3
-
17
-
-
0034648063
-
Neuroprotection by MAPK/ERK kinase inhibition with U0126 against oxidative stress in a mouse neuronal cell line and rat primary cultured cortical neurons
-
Satoh T, Nakatsuka D, Watanabe Y, Nagata I, Kikuchi H and Namura S: Neuroprotection by MAPK/ERK kinase inhibition with U0126 against oxidative stress in a mouse neuronal cell line and rat primary cultured cortical neurons. Neurosci Lett 288: 163-166, 2000.
-
(2000)
Neurosci Lett
, vol.288
, pp. 163-166
-
-
Satoh, T.1
Nakatsuka, D.2
Watanabe, Y.3
Nagata, I.4
Kikuchi, H.5
Namura, S.6
-
18
-
-
67649383498
-
Janus kinase 2 inhibitor AG490 inhibits the STAT3 signaling pathway by suppressing protein translation of gp130
-
Seo IA, Lee HK, Shin YK, et al: Janus kinase 2 inhibitor AG490 inhibits the STAT3 signaling pathway by suppressing protein translation of gp130. Korean J Physiol Pharmacol 13: 131-138, 2009.
-
(2009)
Korean J Physiol Pharmacol
, vol.13
, pp. 131-138
-
-
Seo, I.A.1
Lee, H.K.2
Shin, Y.K.3
-
19
-
-
0033634827
-
Structural determinants of phosphoinositide 3-kinase inhibition by wortmannin, LY294002, quercetin, myricetin, and staurosporine
-
Walker EH, Pacold ME, Perisic O, et al: Structural determinants of phosphoinositide 3-kinase inhibition by wortmannin, LY294002, quercetin, myricetin, and staurosporine. Mol Cell 6: 909-919, 2000.
-
(2000)
Mol Cell
, vol.6
, pp. 909-919
-
-
Walker, E.H.1
Pacold, M.E.2
Perisic, O.3
-
20
-
-
14444279192
-
Identification of a novel inhibitor of mitogen-activated protein kinase kinase
-
Favata MF, Horiuchi KY, Manos EJ, et al: Identification of a novel inhibitor of mitogen-activated protein kinase kinase. J Biol Chem 273: 18623-18632, 1998.
-
(1998)
J Biol Chem
, vol.273
, pp. 18623-18632
-
-
Favata, M.F.1
Horiuchi, K.Y.2
Manos, E.J.3
-
21
-
-
10344258041
-
Targeting the mitogen-activated protein kinase cascade to treat cancer
-
Sebolt-Leopold JS and Herrera R: Targeting the mitogen-activated protein kinase cascade to treat cancer. Nat Rev Cancer 4: 937-947, 2004.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 937-947
-
-
Sebolt-Leopold, J.S.1
Herrera, R.2
-
22
-
-
62549148270
-
P53 represses c-Myc through induction of the tumor suppressor miR-145
-
Sachdeva M, Zhu S, Wu F, et al: p53 represses c-Myc through induction of the tumor suppressor miR-145. Proc Natl Acad Sci USA 106: 3207-3212, 2009.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 3207-3212
-
-
Sachdeva, M.1
Zhu, S.2
Wu, F.3
-
23
-
-
84864451711
-
Forced expression of miR-143 represses ERK5/c-Myc and p68/p72 signaling in concert with miR-145 in gut tumors of ApcMin Mice
-
Takaoka Y, Shimizu Y, Hasegawa H, et al: Forced expression of miR-143 represses ERK5/c-Myc and p68/p72 signaling in concert with miR-145 in gut tumors of ApcMin Mice. PLoS One 7: e42137, 2012.
-
(2012)
PLoS One
, vol.7
-
-
Takaoka, Y.1
Shimizu, Y.2
Hasegawa, H.3
-
24
-
-
84872682314
-
Human lung cancer cell line SPC-A1 contains cells with characteristics of cancer stem cells
-
Zhou CH, Yang SF and Li PQ: Human lung cancer cell line SPC-A1 contains cells with characteristics of cancer stem cells. Neoplasma 59: 685-692, 2012.
-
(2012)
Neoplasma
, vol.59
, pp. 685-692
-
-
Zhou, C.H.1
Yang, S.F.2
Li, P.Q.3
-
25
-
-
84867863624
-
MiR-145 regulates PAK4 via the MAPK pathway and exhibits an antitumor effect in human colon cells
-
Wang Z, Zhang X, Yang Z, et al: MiR-145 regulates PAK4 via the MAPK pathway and exhibits an antitumor effect in human colon cells. Biochem Biophys Res Commun 427: 444-449, 2012.
-
(2012)
Biochem Biophys Res Commun
, vol.427
, pp. 444-449
-
-
Wang, Z.1
Zhang, X.2
Yang, Z.3
-
26
-
-
78650305974
-
MiR-145-dependent targeting of junctional adhesion molecule A and modulation of fascin expression are associated with reduced breast cancer cell motility and invasiveness
-
Gotte M, Mohr C, Koo CY, et al: miR-145-dependent targeting of junctional adhesion molecule A and modulation of fascin expression are associated with reduced breast cancer cell motility and invasiveness. Oncogene 29: 6569-6580, 2010.
-
(2010)
Oncogene
, vol.29
, pp. 6569-6580
-
-
Gotte, M.1
Mohr, C.2
Koo, C.Y.3
-
27
-
-
75349110926
-
Structural and mechanistic underpinnings of the differential drug sensitivity of EGFR mutations in non-small cell lung cancer
-
Eck MJ and Yun CH: Structural and mechanistic underpinnings of the differential drug sensitivity of EGFR mutations in non-small cell lung cancer. Biochim Biophys Acta 1804: 559-566, 2010.
-
(2010)
Biochim Biophys Acta
, vol.1804
, pp. 559-566
-
-
Eck, M.J.1
Yun, C.H.2
-
28
-
-
0038505594
-
Expression of epidermal growth factor receptor (EGFR) and downstream-activated peptides in surgically excised non-small-cell lung cancer (NSCLC)
-
Mukohara T, Kudoh S, Yamauchi S, et al: Expression of epidermal growth factor receptor (EGFR) and downstream-activated peptides in surgically excised non-small-cell lung cancer (NSCLC). Lung Cancer 41: 123-130, 2003.
-
(2003)
Lung Cancer
, vol.41
, pp. 123-130
-
-
Mukohara, T.1
Kudoh, S.2
Yamauchi, S.3
-
29
-
-
48249114422
-
EML4-ALK fusion gene and efficacy of an ALK kinase inhibitor in lung cancer
-
Koivunen JP, Mermel C, Zejnullahu K, et al: EML4-ALK fusion gene and efficacy of an ALK kinase inhibitor in lung cancer. Clin Cancer Res 14: 4275-4283, 2008.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 4275-4283
-
-
Koivunen, J.P.1
Mermel, C.2
Zejnullahu, K.3
-
30
-
-
13644252983
-
A cell-based immunocytochemical assay for monitoring kinase signaling pathways and drug efficacy
-
Chen H, Kovar J, Sissons S, et al: A cell-based immunocytochemical assay for monitoring kinase signaling pathways and drug efficacy. Anal Biochem 338: 136-142, 2005.
-
(2005)
Anal Biochem
, vol.338
, pp. 136-142
-
-
Chen, H.1
Kovar, J.2
Sissons, S.3
|