메뉴 건너뛰기




Volumn 273, Issue 1-2, 2014, Pages 1-7

B cell follicle-like structures in multiple sclerosis-With focus on the role of B cell activating factor

Author keywords

B cell activating factor; B lymphocytes; Follicle like structures; Meningeal inflammation; Multiple sclerosis

Indexed keywords

B CELL ACTIVATING FACTOR; CD20 ANTIGEN; CD3 ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; CXCL13 CHEMOKINE; INTERLEUKIN 17; KI 67 ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; STROMAL CELL DERIVED FACTOR 1; SYNDECAN 1;

EID: 84904102114     PISSN: 01655728     EISSN: 18728421     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2014.05.010     Document Type: Review
Times cited : (40)

References (52)
  • 1
    • 33344475672 scopus 로고    scopus 로고
    • Lymphoid neogenesis in chronic inflammatory diseases
    • Aloisi F., Pujol-Borrell R. Lymphoid neogenesis in chronic inflammatory diseases. Nature Reviews Immunology 2006, 6(3):205-217.
    • (2006) Nature Reviews Immunology , vol.6 , Issue.3 , pp. 205-217
    • Aloisi, F.1    Pujol-Borrell, R.2
  • 2
    • 47249163192 scopus 로고    scopus 로고
    • Lymphoid chemokines in chronic neuroinflammation
    • Aloisi F., et al. Lymphoid chemokines in chronic neuroinflammation. J. Neuroimmunol. 2008, 198(1-2):106-112.
    • (2008) J. Neuroimmunol. , vol.198 , Issue.1-2 , pp. 106-112
    • Aloisi, F.1
  • 3
    • 33744944277 scopus 로고    scopus 로고
    • CXC chemokine ligand 13 plays a role in experimental autoimmune encephalomyelitis
    • Bagaeva L.V., et al. CXC chemokine ligand 13 plays a role in experimental autoimmune encephalomyelitis. J. Immunol. 2006, 176(12):7676-7685.
    • (2006) J. Immunol. , vol.176 , Issue.12 , pp. 7676-7685
    • Bagaeva, L.V.1
  • 4
    • 33748319513 scopus 로고    scopus 로고
    • Myelin oligodendrocyte glycoprotein-specific T and B cells cooperate to induce a Devic-like disease in mice
    • Bettelli E., et al. Myelin oligodendrocyte glycoprotein-specific T and B cells cooperate to induce a Devic-like disease in mice. J. Clin. Invest. 2006, 116(9):2393-2402.
    • (2006) J. Clin. Invest. , vol.116 , Issue.9 , pp. 2393-2402
    • Bettelli, E.1
  • 5
    • 84866534641 scopus 로고    scopus 로고
    • Inducible tertiary lymphoid structures, autoimmunity, and exocrine dysfunction in a novel model of salivary gland inflammation in C57BL/6 mice
    • Bombardieri M., et al. Inducible tertiary lymphoid structures, autoimmunity, and exocrine dysfunction in a novel model of salivary gland inflammation in C57BL/6 mice. J. Immunol. 2012, 189(7):3767-3776.
    • (2012) J. Immunol. , vol.189 , Issue.7 , pp. 3767-3776
    • Bombardieri, M.1
  • 6
    • 70349084196 scopus 로고    scopus 로고
    • Cortical lesions and atrophy associated with cognitive impairment in relapsing-remitting multiple sclerosis
    • Calabrese M., et al. Cortical lesions and atrophy associated with cognitive impairment in relapsing-remitting multiple sclerosis. Arch. Neurol. 2009, 66(9):1144-1150.
    • (2009) Arch. Neurol. , vol.66 , Issue.9 , pp. 1144-1150
    • Calabrese, M.1
  • 8
    • 84867707040 scopus 로고    scopus 로고
    • Meningeal inflammation plays a role in the pathology of primary progressive multiple sclerosis
    • Choi S.R., et al. Meningeal inflammation plays a role in the pathology of primary progressive multiple sclerosis. Brain 2012, 135(10):2925-2937.
    • (2012) Brain , vol.135 , Issue.10 , pp. 2925-2937
    • Choi, S.R.1
  • 9
    • 54149084585 scopus 로고    scopus 로고
    • Multiple sclerosis
    • Compston A., Coles A. Multiple sclerosis. Lancet 2008, 372(9648):1502-1517.
    • (2008) Lancet , vol.372 , Issue.9648 , pp. 1502-1517
    • Compston, A.1    Coles, A.2
  • 10
    • 3342884206 scopus 로고    scopus 로고
    • Recapitulation of B cell differentiation in the central nervous system of patients with multiple sclerosis
    • Corcione A., et al. Recapitulation of B cell differentiation in the central nervous system of patients with multiple sclerosis. Proc. Natl. Acad. Sci. U. S. A. 2004, 101(30):11064-11069.
    • (2004) Proc. Natl. Acad. Sci. U. S. A. , vol.101 , Issue.30 , pp. 11064-11069
    • Corcione, A.1
  • 11
    • 84862186837 scopus 로고    scopus 로고
    • Role of lymphoid chemokines in the development of functional ectopic lymphoid structures in rheumatic autoimmune diseases
    • Corsiero E., et al. Role of lymphoid chemokines in the development of functional ectopic lymphoid structures in rheumatic autoimmune diseases. Immunol. Lett. 2012, 145(1-2):62-67.
    • (2012) Immunol. Lett. , vol.145 , Issue.1-2 , pp. 62-67
    • Corsiero, E.1
  • 12
    • 84876472700 scopus 로고    scopus 로고
    • Effects of CXCL13 inhibition on lymphoid follicles in models of autoimmune disease
    • Finch D.K., et al. Effects of CXCL13 inhibition on lymphoid follicles in models of autoimmune disease. Eur. J. Clin. Investig. 2013, 43(5):501-509.
    • (2013) Eur. J. Clin. Investig. , vol.43 , Issue.5 , pp. 501-509
    • Finch, D.K.1
  • 13
    • 84897946299 scopus 로고    scopus 로고
    • IL-17-induced CXCL12 recruits B cells and induces follicle formation in BALT in the absence of differentiated FDCs
    • Fleige H., et al. IL-17-induced CXCL12 recruits B cells and induces follicle formation in BALT in the absence of differentiated FDCs. J. Exp. Med. 2014, 211(4):643-651.
    • (2014) J. Exp. Med. , vol.211 , Issue.4 , pp. 643-651
    • Fleige, H.1
  • 14
    • 48849117376 scopus 로고    scopus 로고
    • B cells and multiple sclerosis
    • Franciotta D., et al. B cells and multiple sclerosis. Lancet Neurol. 2008, 7(9):852-858.
    • (2008) Lancet Neurol. , vol.7 , Issue.9 , pp. 852-858
    • Franciotta, D.1
  • 15
    • 78650978163 scopus 로고    scopus 로고
    • Cerebrospinal BAFF and Epstein-Barr virus-specific oligoclonal bands in multiple sclerosis and other inflammatory demyelinating neurological diseases
    • Franciotta D., et al. Cerebrospinal BAFF and Epstein-Barr virus-specific oligoclonal bands in multiple sclerosis and other inflammatory demyelinating neurological diseases. J. Neuroimmunol. 2011, 230(1-2):160-163.
    • (2011) J. Neuroimmunol. , vol.230 , Issue.1-2 , pp. 160-163
    • Franciotta, D.1
  • 16
    • 39049142995 scopus 로고    scopus 로고
    • B-cell depletion with rituximab in relapsing-remitting multiple sclerosis
    • Hauser S.L., et al. B-cell depletion with rituximab in relapsing-remitting multiple sclerosis. N. Engl. J. Med. 2008, 358(7):676-688.
    • (2008) N. Engl. J. Med. , vol.358 , Issue.7 , pp. 676-688
    • Hauser, S.L.1
  • 17
    • 84897368225 scopus 로고    scopus 로고
    • Rituximab for relapsing-remitting multiple sclerosis
    • He D., et al. Rituximab for relapsing-remitting multiple sclerosis. Cochrane Database Syst. Rev. 2013, 12.
    • (2013) Cochrane Database Syst. Rev. , vol.12
    • He, D.1
  • 18
    • 77956404064 scopus 로고    scopus 로고
    • CXCL13 blockade disrupts B lymphocyte organization in tertiary lymphoid structures without altering B cell receptor bias or preventing diabetes in nonobese diabetic mice
    • Henry R.A., Kendall P.L. CXCL13 blockade disrupts B lymphocyte organization in tertiary lymphoid structures without altering B cell receptor bias or preventing diabetes in nonobese diabetic mice. J. Immunol. 2010, 185(3):1460-1465.
    • (2010) J. Immunol. , vol.185 , Issue.3 , pp. 1460-1465
    • Henry, R.A.1    Kendall, P.L.2
  • 19
    • 0035109174 scopus 로고    scopus 로고
    • Lymphoid neogenesis: de novo formation of lymphoid tissue in chronic inflammation through expression of homing chemokines
    • Hjelmström P. Lymphoid neogenesis: de novo formation of lymphoid tissue in chronic inflammation through expression of homing chemokines. J. Leukoc. Biol. 2001, 69(3):331-339.
    • (2001) J. Leukoc. Biol. , vol.69 , Issue.3 , pp. 331-339
    • Hjelmström, P.1
  • 20
    • 80052927697 scopus 로고    scopus 로고
    • Meningeal inflammation is widespread and linked to cortical pathology in multiple sclerosis
    • Howell O.W., et al. Meningeal inflammation is widespread and linked to cortical pathology in multiple sclerosis. Brain 2011, 134(9):2755-2771.
    • (2011) Brain , vol.134 , Issue.9 , pp. 2755-2771
    • Howell, O.W.1
  • 21
    • 70349577131 scopus 로고    scopus 로고
    • Meningeal inflammation is not associated with cortical demyelination in chronic multiple sclerosis
    • Kooi E.-J.Ms, et al. Meningeal inflammation is not associated with cortical demyelination in chronic multiple sclerosis. J. Neuropathol. Exp. Neurol. 2009, 68(9):1021-1028.
    • (2009) J. Neuropathol. Exp. Neurol. , vol.68 , Issue.9 , pp. 1021-1028
    • Kooi, E.-J.M.1
  • 22
    • 20244384231 scopus 로고    scopus 로고
    • BAFF is produced by astrocytes and up-regulated in multiple sclerosis lesions and primary central nervous system lymphoma
    • Krumbholz M., et al. BAFF is produced by astrocytes and up-regulated in multiple sclerosis lesions and primary central nervous system lymphoma. J. Exp. Med. 2005, 201(2):195-200.
    • (2005) J. Exp. Med. , vol.201 , Issue.2 , pp. 195-200
    • Krumbholz, M.1
  • 23
    • 30344446249 scopus 로고    scopus 로고
    • Chemokines in multiple sclerosis: CXCL12 and CXCL13 up-regulation is differentially linked to CNS immune cell recruitment
    • Krumbholz M., et al. Chemokines in multiple sclerosis: CXCL12 and CXCL13 up-regulation is differentially linked to CNS immune cell recruitment. Brain 2006, 129(Pt 1):200-211.
    • (2006) Brain , vol.129 , Issue.PART 1 , pp. 200-211
    • Krumbholz, M.1
  • 24
    • 44949253997 scopus 로고    scopus 로고
    • Interferon-β increases BAFF levels in multiple sclerosis: implications for B cell autoimmunity
    • Krumbholz M., et al. Interferon-β increases BAFF levels in multiple sclerosis: implications for B cell autoimmunity. Brain 2008, 131(6):1455-1463.
    • (2008) Brain , vol.131 , Issue.6 , pp. 1455-1463
    • Krumbholz, M.1
  • 25
    • 84868525833 scopus 로고    scopus 로고
    • B cells and antibodies in multiple sclerosis pathogenesis and therapy
    • Krumbholz M., et al. B cells and antibodies in multiple sclerosis pathogenesis and therapy. Nat. Rev. Neurol. 2012, 8(11):613-623.
    • (2012) Nat. Rev. Neurol. , vol.8 , Issue.11 , pp. 613-623
    • Krumbholz, M.1
  • 26
    • 49749121806 scopus 로고    scopus 로고
    • Cerebrospinal fluid B cells correlate with early brain inflammation in multiple sclerosis
    • Kuenz B., et al. Cerebrospinal fluid B cells correlate with early brain inflammation in multiple sclerosis. PLoS One 2008, 3(7):1-7.
    • (2008) PLoS One , vol.3 , Issue.7 , pp. 1-7
    • Kuenz, B.1
  • 27
    • 33947509525 scopus 로고    scopus 로고
    • The immunopathology of multiple sclerosis: an overview
    • Lassmann H., Brück W., Lucchinetti C.F. The immunopathology of multiple sclerosis: an overview. Brain Pathol. 2007, 17(2):210-218.
    • (2007) Brain Pathol. , vol.17 , Issue.2 , pp. 210-218
    • Lassmann, H.1    Brück, W.2    Lucchinetti, C.F.3
  • 28
    • 84868535759 scopus 로고    scopus 로고
    • Progressive multiple sclerosis: pathology and pathogenesis
    • Lassmann H., van Horssen J., Mahad D. Progressive multiple sclerosis: pathology and pathogenesis. Nat. Rev. Neurol. 2012, 8(11):647-656.
    • (2012) Nat. Rev. Neurol. , vol.8 , Issue.11 , pp. 647-656
    • Lassmann, H.1    van Horssen, J.2    Mahad, D.3
  • 29
    • 84855917402 scopus 로고    scopus 로고
    • AHR drives the development of gut ILC22 cells and postnatal lymphoid tissues via pathways dependent on and independent of Notch
    • Lee J.S., et al. AHR drives the development of gut ILC22 cells and postnatal lymphoid tissues via pathways dependent on and independent of Notch. Nat. Immunol. 2012, 13(2):144-151.
    • (2012) Nat. Immunol. , vol.13 , Issue.2 , pp. 144-151
    • Lee, J.S.1
  • 30
    • 84873458628 scopus 로고    scopus 로고
    • Multiple sclerosis risk genotypes correlate with an elevated cerebrospinal fluid level of the suggested prognostic marker CXCL13
    • Lindén M., et al. Multiple sclerosis risk genotypes correlate with an elevated cerebrospinal fluid level of the suggested prognostic marker CXCL13. Mult. Scler. J. 2013, 19(7):863-870.
    • (2013) Mult. Scler. J. , vol.19 , Issue.7 , pp. 863-870
    • Lindén, M.1
  • 31
    • 79551695835 scopus 로고    scopus 로고
    • Related B cell clones populate the meninges and parenchyma of patients with multiple sclerosis
    • Lovato L., et al. Related B cell clones populate the meninges and parenchyma of patients with multiple sclerosis. Brain 2011, 134(2):534-541.
    • (2011) Brain , vol.134 , Issue.2 , pp. 534-541
    • Lovato, L.1
  • 32
    • 0342906187 scopus 로고    scopus 로고
    • Heterogeneity of multiple sclerosis lesions: implications for the pathogenesis of demyelination
    • Lucchinetti C., et al. Heterogeneity of multiple sclerosis lesions: implications for the pathogenesis of demyelination. Ann. Neurol. 2000, 47(6):707-717.
    • (2000) Ann. Neurol. , vol.47 , Issue.6 , pp. 707-717
    • Lucchinetti, C.1
  • 33
    • 83155173565 scopus 로고    scopus 로고
    • Inflammatory cortical demyelination in early multiple sclerosis
    • Lucchinetti C.F., et al. Inflammatory cortical demyelination in early multiple sclerosis. N. Engl. J. Med. 2011, 365(23):2188-2197.
    • (2011) N. Engl. J. Med. , vol.365 , Issue.23 , pp. 2188-2197
    • Lucchinetti, C.F.1
  • 34
    • 1242340285 scopus 로고    scopus 로고
    • Intracerebral expression of CXCL13 and BAFF is accompanied by formation of lymphoid follicle-like structures in the meninges of mice with relapsing experimental autoimmune encephalomyelitis
    • Magliozzi R., et al. Intracerebral expression of CXCL13 and BAFF is accompanied by formation of lymphoid follicle-like structures in the meninges of mice with relapsing experimental autoimmune encephalomyelitis. J. Neuroimmunol. 2004, 148(1-2):11-23.
    • (2004) J. Neuroimmunol. , vol.148 , Issue.1-2 , pp. 11-23
    • Magliozzi, R.1
  • 35
    • 34249700046 scopus 로고    scopus 로고
    • Meningeal B-cell follicles in secondary progressive multiple sclerosis associate with early onset of disease and severe cortical pathology
    • Magliozzi R., et al. Meningeal B-cell follicles in secondary progressive multiple sclerosis associate with early onset of disease and severe cortical pathology. Brain 2007, 130(4):1089-1104.
    • (2007) Brain , vol.130 , Issue.4 , pp. 1089-1104
    • Magliozzi, R.1
  • 36
    • 78249280011 scopus 로고    scopus 로고
    • A gradient of neuronal loss and meningeal inflammation in multiple sclerosis
    • Magliozzi R., et al. A gradient of neuronal loss and meningeal inflammation in multiple sclerosis. Ann. Neurol. 2010, 68(4):477-493.
    • (2010) Ann. Neurol. , vol.68 , Issue.4 , pp. 477-493
    • Magliozzi, R.1
  • 37
    • 84871977359 scopus 로고    scopus 로고
    • B-cell enrichment and Epstein-Barr virus infection in inflammatory cortical lesions in secondary progressive multiple sclerosis
    • Magliozzi R., et al. B-cell enrichment and Epstein-Barr virus infection in inflammatory cortical lesions in secondary progressive multiple sclerosis. J. Neuropathol. Exp. Neurol. 2013, 72(1):29-41.
    • (2013) J. Neuropathol. Exp. Neurol. , vol.72 , Issue.1 , pp. 29-41
    • Magliozzi, R.1
  • 38
    • 84890819172 scopus 로고    scopus 로고
    • MHC class II-dependent B cell APC function is required for induction of CNS autoimmunity independent of myelin-specific antibodies
    • Molnarfi N., et al. MHC class II-dependent B cell APC function is required for induction of CNS autoimmunity independent of myelin-specific antibodies. J. Exp. Med. 2013, 210(13):2921-2937.
    • (2013) J. Exp. Med. , vol.210 , Issue.13 , pp. 2921-2937
    • Molnarfi, N.1
  • 39
    • 84884491220 scopus 로고    scopus 로고
    • Contribution of cortical lesion subtypes at 7T MRI to physical and cognitive performance in MS
    • Nielsen A.S., et al. Contribution of cortical lesion subtypes at 7T MRI to physical and cognitive performance in MS. Neurology 2013, 81(7):641-649.
    • (2013) Neurology , vol.81 , Issue.7 , pp. 641-649
    • Nielsen, A.S.1
  • 40
    • 67650082863 scopus 로고    scopus 로고
    • Antibodies produced by clonally expanded plasma cells in multiple sclerosis cerebrospinal fluid
    • Owens G.P., et al. Antibodies produced by clonally expanded plasma cells in multiple sclerosis cerebrospinal fluid. Ann. Neurol. 2009, 65(6):639-649.
    • (2009) Ann. Neurol. , vol.65 , Issue.6 , pp. 639-649
    • Owens, G.P.1
  • 41
    • 84355166761 scopus 로고    scopus 로고
    • Th17 cells induce ectopic lymphoid follicles in central nervous system tissue inflammation
    • Peters A., et al. Th17 cells induce ectopic lymphoid follicles in central nervous system tissue inflammation. Immunity 2011, 35(6):986-996.
    • (2011) Immunity , vol.35 , Issue.6 , pp. 986-996
    • Peters, A.1
  • 42
    • 84859100978 scopus 로고    scopus 로고
    • Meningeal and cortical grey matter pathology in multiple sclerosis
    • Popescu B.F.G., Lucchinetti C.F. Meningeal and cortical grey matter pathology in multiple sclerosis. BMC Neurol. 2012, 12(1):11.
    • (2012) BMC Neurol. , vol.12 , Issue.1 , pp. 11
    • Popescu, B.F.G.1    Lucchinetti, C.F.2
  • 43
    • 79959494654 scopus 로고    scopus 로고
    • Multiple sclerosis: BAFF and CXCL13 in cerebrospinal fluid
    • Ragheb S., et al. Multiple sclerosis: BAFF and CXCL13 in cerebrospinal fluid. Mult. Scler. J. 2011, 17(7):819-829.
    • (2011) Mult. Scler. J. , vol.17 , Issue.7 , pp. 819-829
    • Ragheb, S.1
  • 44
    • 84874566824 scopus 로고    scopus 로고
    • Systemic inflammation in progressive multiple sclerosis involves follicular T-helper, Th17- and activated B-cells and correlates with progression
    • Romme Christensen J., et al. Systemic inflammation in progressive multiple sclerosis involves follicular T-helper, Th17- and activated B-cells and correlates with progression. PLoS One 2013, 8(3):1-11.
    • (2013) PLoS One , vol.8 , Issue.3 , pp. 1-11
    • Romme Christensen, J.1
  • 45
    • 84901201410 scopus 로고    scopus 로고
    • Natalizumab in progressive MS: results of an open-label, phase 2A, proof-of-concept trial
    • Romme Christensen J., et al. Natalizumab in progressive MS: results of an open-label, phase 2A, proof-of-concept trial. Neurology 2014, 1-9.
    • (2014) Neurology , pp. 1-9
    • Romme Christensen, J.1
  • 46
    • 73349109797 scopus 로고    scopus 로고
    • Increased cerebrospinal fluid concentrations of the chemokine CXCL13 in active MS
    • Sellebjerg F., et al. Increased cerebrospinal fluid concentrations of the chemokine CXCL13 in active MS. Neurology 2009, 73(23):2003-2010.
    • (2009) Neurology , vol.73 , Issue.23 , pp. 2003-2010
    • Sellebjerg, F.1
  • 47
    • 2442708947 scopus 로고    scopus 로고
    • Detection of ectopic B-cell follicles with germinal centers in the meninges of patients with secondary progressive multiple sclerosis
    • Serafini B., et al. Detection of ectopic B-cell follicles with germinal centers in the meninges of patients with secondary progressive multiple sclerosis. Brain Pathol. 2004, 14(2):164-174.
    • (2004) Brain Pathol. , vol.14 , Issue.2 , pp. 164-174
    • Serafini, B.1
  • 48
    • 58149374594 scopus 로고    scopus 로고
    • Expression of TWEAK and its receptor Fn14 in the multiple sclerosis brain: Implications for inflammatory tissue injury
    • Serafini B., et al. Expression of TWEAK and its receptor Fn14 in the multiple sclerosis brain: Implications for inflammatory tissue injury. J. Neuropathol. Exp. Neurol. 2008, 67(12):1137-1148.
    • (2008) J. Neuropathol. Exp. Neurol. , vol.67 , Issue.12 , pp. 1137-1148
    • Serafini, B.1
  • 49
    • 77954725231 scopus 로고    scopus 로고
    • Epstein-Barr virus latent infection and BAFF expression in B cells in the multiple sclerosis brain: implications for viral persistence and intrathecal B-cell activation
    • Serafini B., et al. Epstein-Barr virus latent infection and BAFF expression in B cells in the multiple sclerosis brain: implications for viral persistence and intrathecal B-cell activation. J. Neuropathol. Exp. Neurol. 2010, 69(7):677-693.
    • (2010) J. Neuropathol. Exp. Neurol. , vol.69 , Issue.7 , pp. 677-693
    • Serafini, B.1
  • 50
    • 48749091530 scopus 로고    scopus 로고
    • Requirement for lymphoid tissue-inducer cells in isolated follicle formation and T cell-independent immunoglobulin A generation in the gut
    • Tsuji M., et al. Requirement for lymphoid tissue-inducer cells in isolated follicle formation and T cell-independent immunoglobulin A generation in the gut. Immunity 2008, 29(2):261-271.
    • (2008) Immunity , vol.29 , Issue.2 , pp. 261-271
    • Tsuji, M.1
  • 51
    • 82655186611 scopus 로고    scopus 로고
    • Cortical injury in multiple sclerosis; the role of the immune system
    • Walker C.A., Huttner A.J., O'Connor K.C. Cortical injury in multiple sclerosis; the role of the immune system. BMC Neurol. 2011, 11(1):152-158.
    • (2011) BMC Neurol. , vol.11 , Issue.1 , pp. 152-158
    • Walker, C.A.1    Huttner, A.J.2    O'Connor, K.C.3
  • 52
    • 84903936591 scopus 로고    scopus 로고
    • Anti-CXCL13 antibody can inhibit the formation of gastric lymphoid follicles induced by Helicobacter infection
    • [Epub ahead of print]
    • Yamamoto K., et al. Anti-CXCL13 antibody can inhibit the formation of gastric lymphoid follicles induced by Helicobacter infection. Mucosal Immunol 2014, [Epub ahead of print]. 10.1038/mi.2014.14.
    • (2014) Mucosal Immunol
    • Yamamoto, K.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.