Rapid evolution of BRCA1 and BRCA2 in humans and other primates

BMC Evolutionary Biology

Volumn 14, Issue 1, 2014, Pages

  Lou, Dianne I ^a   McBee, Ross M ^a   Le, Uyen Q ^a   Stone, Anne C ^b   Wilkerson, Gregory K ^c   Demogines, Ann M ^a   Sawyer, Sara L ^a  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^b ARIZONA STATE UNIVERSITY   (United States)

^c UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

Cell cycle; DNA damage response; Positive selection; Simian primates

Indexed keywords

MACACA MULATTA; PAN; PAN PANISCUS; PAN TROGLODYTES; PRIMATES; SIMIAE;

AMINO ACID; CANCER; CHROMOSOME; DNA; GENE EXPRESSION; HUMAN EVOLUTION; MUTATION; PHENOTYPE; POLYMORPHISM; PRIMATE; PROTEIN;

BRCA1 PROTEIN; BRCA1 PROTEIN, HUMAN; BRCA2 PROTEIN; BRCA2 PROTEIN, HUMAN;

AMINO ACID SEQUENCE; ANIMAL; ARTICLE; BREAST TUMOR; CHEMICAL STRUCTURE; CHEMISTRY; DNA REPAIR; EXON; FEMALE; GENETIC POLYMORPHISM; GENETIC SELECTION; GENETICS; HUMAN; METABOLISM; MOLECULAR EVOLUTION; MOLECULAR GENETICS; MUTATION; OVARY TUMOR; PRIMATE; SEQUENCE ALIGNMENT; TUMOR SUPPRESSOR GENE; VIROLOGY;

AMINO ACID SEQUENCE; ANIMALS; BRCA1 PROTEIN; BRCA2 PROTEIN; BREAST NEOPLASMS; DNA REPAIR; EVOLUTION, MOLECULAR; EXONS; FEMALE; GENES, BRCA1; GENES, BRCA2; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; OVARIAN NEOPLASMS; POLYMORPHISM, GENETIC; PRIMATES; SELECTION, GENETIC; SEQUENCE ALIGNMENT;

EID: 84904086866     PISSN: None     EISSN: 14712148     Source Type: Journal    
DOI: 10.1186/1471-2148-14-155     Document Type: Article

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