PDZ domain-binding motif regulates cardiomyocyte compartment-specific nav1.5 channel expression and function

Circulation

Volumn 130, Issue 2, 2014, Pages 147-160

  Shy, Diana ^a   Gillet, Ludovic ^a   Ogrodnik, Jakob ^a   Albesa, Maxime ^a   Verkerk, Arie O ^b   Wolswinkel, Rianne ^c   Rougier, Jean Sébastien ^a   Barc, Julien ^c,d   Essers, Maria C ^a   Syam, Ninda ^a   Marsman, Roos F ^c   Van Mil, Anneke M ^e   Rotman, Samuel ^f   Redon, Richard ^g,h,i,j   Bezzina, Connie R ^c   Remme, Carol Ann ^c   Abriel, Hugues ^a  

^a UNIVERSITY OF BERN   (Switzerland)

^b Department of Anatomy Embryology and Physiology   (Switzerland)

^c UNIVERSITY OF AMSTERDAM   (Netherlands)

^d ROYAL NETHERLANDS ACADEMY OF ARTS AND SCIENCES   (Netherlands)

^e LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^f UNIVERSITY OF LAUSANNE   (Switzerland)

^g L INSTITUT DU THORAX   (France)

^h CNRS   (France)

ⁱ UNIVERSITÉ DE NANTES   (France)

^j NANTES UNIVERSITY HOSPITAL   (France)

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Author keywords

Dystrophin; Sodium channels; Syntrophin

Indexed keywords

BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; PDZ PROTEIN; SODIUM CHANNEL NAV1.5;

ANIMAL TISSUE; ANISOTROPY; ARTICLE; BRUGADA SYNDROME; CONTROLLED STUDY; GENETIC SCREENING; HEART MUSCLE CELL; HEART VENTRICLE CONDUCTION; HUMAN; HUMAN CELL; IN VIVO STUDY; INTERNALIZATION; MISSENSE MUTATION; MOUSE; NONHUMAN; PDZ DOMAIN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; SODIUM CURRENT;

DYSTROPHIN; SODIUM CHANNELS; SYNTROPHIN;

ANIMALS; GENE EXPRESSION REGULATION; GENE KNOCK-IN TECHNIQUES; HEK293 CELLS; HUMANS; MICE; MYOCYTES, CARDIAC; NAV1.5 VOLTAGE-GATED SODIUM CHANNEL; PDZ DOMAINS; PROTEIN INTERACTION DOMAINS AND MOTIFS;

EID: 84904053841     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.113.007852     Document Type: Article

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