메뉴 건너뛰기




Volumn 94, Issue 1, 2012, Pages 58-65

Connexin43 ablation in foetal atrial myocytes decreases electrical coupling, partner connexins, and sodium current

Author keywords

Atrial cell to cell coupling; Connexin; Cx43 ablation; Sodium current

Indexed keywords

CONNEXIN 40; CONNEXIN 43; CONNEXIN 45;

EID: 84859018881     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvs025     Document Type: Article
Times cited : (66)

References (37)
  • 1
    • 0036945719 scopus 로고    scopus 로고
    • Localization of sodium channels in intercalated disks modulates cardiac conduction
    • Kucera JP, Rohr S, Rudy Y. Localization of sodium channels in intercalated disks modulates cardiac conduction. Circ Res 2002;91:1176-1182.
    • (2002) Circ Res , vol.91 , pp. 1176-1182
    • Kucera, J.P.1    Rohr, S.2    Rudy, Y.3
  • 2
    • 1642370591 scopus 로고    scopus 로고
    • Distinct subcellular localization of different sodium channel alpha and beta subunits in single ventricular myocytes from mouse heart
    • Maier SK, Westenbroek RE, McCormick KA, Curtis R, Scheuer T, Catterall WA. Distinct subcellular localization of different sodium channel alpha and beta subunits in single ventricular myocytes from mouse heart. Circulation 2004;109:1421-1427.
    • (2004) Circulation , vol.109 , pp. 1421-1427
    • Maier, S.K.1    Westenbroek, R.E.2    McCormick, K.A.3    Curtis, R.4    Scheuer, T.5    Catterall, W.A.6
  • 3
    • 0037133689 scopus 로고    scopus 로고
    • An unexpected role for brain-type sodium channels in coupling of cell surface depolarization to contraction in the heart
    • Maier SK, Westenbroek RE, Schenkman KA, Feigl EO, Scheuer T, Catterall WA. An unexpected role for brain-type sodium channels in coupling of cell surface depolarization to contraction in the heart. Proc Natl Acad Sci USA 2002;99:4073-4078.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 4073-4078
    • Maier, S.K.1    Westenbroek, R.E.2    Schenkman, K.A.3    Feigl, E.O.4    Scheuer, T.5    Catterall, W.A.6
  • 4
    • 79751537880 scopus 로고    scopus 로고
    • SAP97 and dystrophin macromolecular complexes determine two pools of cardiac sodium channels Nav1.5 in cardiomyocytes
    • Petitprez S, Zmoos AF, Ogrodnik J, Balse E, Raad N, El-Haou S et al. SAP97 and dystrophin macromolecular complexes determine two pools of cardiac sodium channels Nav1.5 in cardiomyocytes. Circ Res 2011;108:294-304.
    • (2011) Circ Res , vol.108 , pp. 294-304
    • Petitprez, S.1    Zmoos, A.F.2    Ogrodnik, J.3    Balse, E.4    Raad, N.5    El-Haou, S.6
  • 5
    • 51749110724 scopus 로고    scopus 로고
    • Remodelling of gap junctions and connexin expression in diseased myocardium
    • Severs NJ, Bruce AF, Dupont E, Rothery S. Remodelling of gap junctions and connexin expression in diseased myocardium. Cardiovascular Res 2008;80:9-19.
    • (2008) Cardiovascular Res , vol.80 , pp. 9-19
    • Severs, N.J.1    Bruce, A.F.2    Dupont, E.3    Rothery, S.4
  • 7
    • 67650248283 scopus 로고    scopus 로고
    • C-terminal tagging with eGFP yields new insights into expression of connexin45 but prevents rescue of embryonic lethal connexin45-deficient mice
    • von Maltzahn J, Kreuzberg MM, Matern G, Euwens C, Hoher T, Worsdorfer P et al. C-terminal tagging with eGFP yields new insights into expression of connexin45 but prevents rescue of embryonic lethal connexin45-deficient mice. Eur J Cell Biol 2009; 88:481-494.
    • (2009) Eur J Cell Biol , vol.88 , pp. 481-494
    • Von Maltzahn, J.1    Kreuzberg, M.M.2    Matern, G.3    Euwens, C.4    Hoher, T.5    Worsdorfer, P.6
  • 8
    • 0027282484 scopus 로고
    • Multiple connexins colocalize in canine ventricular myocyte gap junctions
    • Kanter HL, Laing JG, Beyer EC, Green KG, Saffitz JE. Multiple connexins colocalize in canine ventricular myocyte gap junctions. Circ Res 1993;73:344-350.
    • (1993) Circ Res , vol.73 , pp. 344-350
    • Kanter, H.L.1    Laing, J.G.2    Beyer, E.C.3    Green, K.G.4    Saffitz, J.E.5
  • 9
    • 0027218911 scopus 로고
    • The spatial distribution and relative abundance of gap-junctional connexin40 and connexin43 correlate to functional properties of components of the cardiac atrioventricular conduction system
    • Gourdie RG, Severs NJ, Green CR, Rothery S, Germroth P, Thompson RP. The spatial distribution and relative abundance of gap-junctional connexin40 and connexin43 correlate to functional properties of components of the cardiac atrioventricular conduction system. J Cell Sci 1993;105(Pt 4):985-991.
    • (1993) J Cell Sci , vol.105 , Issue.PART 4 , pp. 985-991
    • Gourdie, R.G.1    Severs, N.J.2    Green, C.R.3    Rothery, S.4    Germroth, P.5    Thompson, R.P.6
  • 11
    • 0037094218 scopus 로고    scopus 로고
    • Atrial fibrillation-induced gap junctional remodeling
    • author reply 1709-1710
    • van der Velden HM, Wilders R, Jongsma HJ. Atrial fibrillation-induced gap junctional remodeling. J Am Coll Cardiol 2002;39:1709; author reply 1709-1710.
    • (2002) J Am Coll Cardiol , vol.39 , pp. 1709
    • Van Der Velden, H.M.1    Wilders, R.2    Jongsma, H.J.3
  • 12
    • 77954954398 scopus 로고    scopus 로고
    • Paradigm of genetic mosaicism and lone atrial fibrillation: Physiological characterization of a connexin 43-deletion mutant identified from atrial tissue
    • Thibodeau IL, Xu J, Li Q, Liu G, Lam K, Veinot JP et al. Paradigm of genetic mosaicism and lone atrial fibrillation: physiological characterization of a connexin 43-deletion mutant identified from atrial tissue. Circulation 2010;122:236-244.
    • (2010) Circulation , vol.122 , pp. 236-244
    • Thibodeau, I.L.1    Xu, J.2    Li, Q.3    Liu, G.4    Lam, K.5    Veinot, J.P.6
  • 13
    • 33751318437 scopus 로고    scopus 로고
    • Relative contributions of connexins 40 and 43 to atrial impulse propagation in synthetic strands of neonatal and fetal murine cardiomyocytes
    • Beauchamp P, Yamada KA, Baertschi AJ, Green K, Kanter EM, Saffitz JE et al. Relative contributions of connexins 40 and 43 to atrial impulse propagation in synthetic strands of neonatal and fetal murine cardiomyocytes. Circ Res 2006;99:1216-1224.
    • (2006) Circ Res , vol.99 , pp. 1216-1224
    • Beauchamp, P.1    Yamada, K.A.2    Baertschi, A.J.3    Green, K.4    Kanter, E.M.5    Saffitz, J.E.6
  • 15
    • 0035704411 scopus 로고    scopus 로고
    • Emerging issues of connexin channels: Biophysics fills the gap
    • Harris AL. Emerging issues of connexin channels: biophysics fills the gap. Q Rev Biophys 2001;34:325-472.
    • (2001) Q Rev Biophys , vol.34 , pp. 325-472
    • Harris, A.L.1
  • 16
    • 20444381286 scopus 로고    scopus 로고
    • Functional consequences of heterogeneous gap junction channel formation and its influence in health and disease
    • Cottrell GT, Burt JM. Functional consequences of heterogeneous gap junction channel formation and its influence in health and disease. Biochim Biophys Acta 2005;1711:126-141.
    • (2005) Biochim Biophys Acta , vol.1711 , pp. 126-141
    • Cottrell, G.T.1    Burt, J.M.2
  • 17
    • 0035195813 scopus 로고    scopus 로고
    • Heterotypic gap junction channel formation between heteromeric and homomeric Cx40 and Cx43 connexons
    • Cottrell GT, Burt JM. Heterotypic gap junction channel formation between heteromeric and homomeric Cx40 and Cx43 connexons. Am J Physiol Cell Physiol 2001; 281:C1559-C1567.
    • (2001) Am J Physiol Cell Physiol , vol.281
    • Cottrell, G.T.1    Burt, J.M.2
  • 19
    • 70449719640 scopus 로고    scopus 로고
    • Control of myocyte remodeling in vitro with engineered substrates
    • Geisse NA, Sheehy SP, Parker KK. Control of myocyte remodeling in vitro with engineered substrates. In Vitro Cell Dev Biol Anim 2009;45:343-350.
    • (2009) Vitro Cell Dev Biol Anim , vol.45 , pp. 343-350
    • Geisse, N.A.1    Sheehy, S.P.2    Parker, K.K.3
  • 20
    • 3442896550 scopus 로고    scopus 로고
    • Cardiac connexins Cx43 and Cx45: Formation of diverse gap junction channels with diverse electrical properties
    • Desplantez T, Halliday D, Dupont E, Weingart R. Cardiac connexins Cx43 and Cx45: formation of diverse gap junction channels with diverse electrical properties. Pflugers Arch 2004;448:363-375.
    • (2004) Pflugers Arch , vol.448 , pp. 363-375
    • Desplantez, T.1    Halliday, D.2    Dupont, E.3    Weingart, R.4
  • 21
    • 84855335569 scopus 로고    scopus 로고
    • Cell-to-cell coupling in engineered pairs of rat ventricular cardiomyocytes: Relation between Cx43 immunofluorescence and intercellular electrical conductance
    • McCain M, Desplantez T, Geisse N, Rothen-Rutishauser B, Oberer H, Parker K et al. Cell-to-cell coupling in engineered pairs of rat ventricular cardiomyocytes: relation between Cx43 immunofluorescence and intercellular electrical conductance. Am J Physiol Heart Circ Physiol 2012;302:H443-H450.
    • (2012) Am J Physiol Heart Circ Physiol , vol.302
    • McCain, M.1    Desplantez, T.2    Geisse, N.3    Rothen-Rutishauser, B.4    Oberer, H.5    Parker, K.6
  • 22
    • 0031955758 scopus 로고    scopus 로고
    • Quantitative analysis of dual whole-cell voltage-clamp determination of gap junctional conductance
    • Van Rijen HV, Wilders R, Van Ginneken AC, Jongsma HJ. Quantitative analysis of dual whole-cell voltage-clamp determination of gap junctional conductance. Pflugers Arch 1998;436:141-151.
    • (1998) Pflugers Arch , vol.436 , pp. 141-151
    • Van Rijen, H.V.1    Wilders, R.2    Van Ginneken, A.C.3    Jongsma, H.J.4
  • 24
    • 1942438935 scopus 로고    scopus 로고
    • Biophysical properties of homomeric and heteromultimeric channels formed by cardiac connexins
    • Moreno AP. Biophysical properties of homomeric and heteromultimeric channels formed by cardiac connexins. Cardiovascular Res 2004;62:276-286.
    • (2004) Cardiovascular Res , vol.62 , pp. 276-286
    • Moreno, A.P.1
  • 25
    • 84859312522 scopus 로고    scopus 로고
    • Reduced heterogeneous expression of Cx43 results in decreased Nav1.5 expression and reduced sodium current that accounts for arrhythmia vulnerability in conditional Cx43 knockout mice
    • Nov 16. [Epub ahead of print]
    • Jansen JA, Noorman M, Musa H, Stein M, de Jong S, van der Nagel R et al. Reduced heterogeneous expression of Cx43 results in decreased Nav1.5 expression and reduced sodium current that accounts for arrhythmia vulnerability in conditional Cx43 knockout mice. Heart Rhythm 2011 Nov 16. [Epub ahead of print].
    • (2011) Heart Rhythm
    • Jansen, J.A.1    Noorman, M.2    Musa, H.3    Stein, M.4    De Jong, S.5    Van Der Nagel, R.6
  • 26
    • 0032992532 scopus 로고    scopus 로고
    • Junctional communication between isolated pairs of canine atrial cells is mediated by homogeneous and heterogeneous gap junction channels
    • Elenes S, Rubart M, Moreno AP. Junctional communication between isolated pairs of canine atrial cells is mediated by homogeneous and heterogeneous gap junction channels. J Cardiovasc Electrophysiol 1999;10:990-1004.
    • (1999) J Cardiovasc Electrophysiol , vol.10 , pp. 990-1004
    • Elenes, S.1    Rubart, M.2    Moreno, A.P.3
  • 27
    • 0030939161 scopus 로고    scopus 로고
    • Characterization of gap junction channels in adult rabbit atrial and ventricular myocardium
    • Verheule S, van Kempen MJ, te Welscher PH, Kwak BR, Jongsma HJ. Characterization of gap junction channels in adult rabbit atrial and ventricular myocardium. Circ Res 1997;80:673-681.
    • (1997) Circ Res , vol.80 , pp. 673-681
    • Verheule, S.1    Van Kempen, M.J.2    Te Welscher, P.H.3    Kwak, B.R.4    Jongsma, H.J.5
  • 28
    • 3342896391 scopus 로고    scopus 로고
    • Electrical propagation in synthetic ventricular myocyte strands from germline connexin43 knockout mice
    • Beauchamp P, Choby C, Desplantez T, de Peyer K, Green K, Yamada KA et al. Electrical propagation in synthetic ventricular myocyte strands from germline connexin43 knockout mice. Circ Res 2004;95:170-178.
    • (2004) Circ Res , vol.95 , pp. 170-178
    • Beauchamp, P.1    Choby, C.2    Desplantez, T.3    De Peyer, K.4    Green, K.5    Yamada, K.A.6
  • 29
    • 0034665275 scopus 로고    scopus 로고
    • Synthetic strands of neonatal mouse cardiac myocytes: Structural and electrophysiological properties
    • Thomas SP, Bircher-Lehmann L, Thomas SA, Zhuang J, Saffitz JE, Kleber AG. Synthetic strands of neonatal mouse cardiac myocytes: structural and electrophysiological properties. Circ Res 2000;87:467-473.
    • (2000) Circ Res , vol.87 , pp. 467-473
    • Thomas, S.P.1    Bircher-Lehmann, L.2    Thomas, S.A.3    Zhuang, J.4    Saffitz, J.E.5    Kleber, A.G.6
  • 30
    • 26844537322 scopus 로고    scopus 로고
    • Altered right atrial excitation and propagation in connexin40 knockout mice
    • Bagwe S, Berenfeld O, Vaidya D, Morley GE, Jalife J. Altered right atrial excitation and propagation in connexin40 knockout mice. Circulation 2005;112:2245-2253.
    • (2005) Circulation , vol.112 , pp. 2245-2253
    • Bagwe, S.1    Berenfeld, O.2    Vaidya, D.3    Morley, G.E.4    Jalife, J.5
  • 31
    • 62349094053 scopus 로고    scopus 로고
    • A new diagnostic test for arrhythmogenic right ventricular cardiomyopathy
    • Asimaki A, Tandri H, Huang H, Halushka MK, Gautam S, Basso C et al. A new diagnostic test for arrhythmogenic right ventricular cardiomyopathy. N Engl J Med 2009; 360:1075-1084.
    • (2009) N Engl J Med , vol.360 , pp. 1075-1084
    • Asimaki, A.1    Tandri, H.2    Huang, H.3    Halushka, M.K.4    Gautam, S.5    Basso, C.6
  • 32
    • 33846695393 scopus 로고    scopus 로고
    • Microtubule plus-end-tracking proteins target gap junctions directly from the cell interior to adherens junctions
    • Shaw RM, Fay AJ, Puthenveedu MA, von Zastrow M, Jan YN, Jan LY. Microtubule plus-end-tracking proteins target gap junctions directly from the cell interior to adherens junctions. Cell 2007;128:547-560.
    • (2007) Cell , vol.128 , pp. 547-560
    • Shaw, R.M.1    Fay, A.J.2    Puthenveedu, M.A.3    Von Zastrow, M.4    Jan, Y.N.5    Jan, L.Y.6
  • 33
    • 70349242035 scopus 로고    scopus 로고
    • Loss of plakophilin-2 expression leads to decreased sodium current and slower conduction velocity in cultured cardiac myocytes
    • Sato PY, Musa H, Coombs W, Guerrero-Serna G, Patino GA, Taffet SM et al. Loss of plakophilin-2 expression leads to decreased sodium current and slower conduction velocity in cultured cardiac myocytes. Circ Res 2009;105:523-526.
    • (2009) Circ Res , vol.105 , pp. 523-526
    • Sato, P.Y.1    Musa, H.2    Coombs, W.3    Guerrero-Serna, G.4    Patino, G.A.5    Taffet, S.M.6
  • 35
    • 18844479760 scopus 로고    scopus 로고
    • Basic mechanisms of cardiac impulse propagation and associated arrhythmias
    • Kleber AG, Rudy Y. Basic mechanisms of cardiac impulse propagation and associated arrhythmias. Physiol Rev 2004;84:431-488.
    • (2004) Physiol Rev , vol.84 , pp. 431-488
    • Kleber, A.G.1    Rudy, Y.2
  • 36
    • 0037005778 scopus 로고    scopus 로고
    • Relative expression of immunolocalized connexins 40 and 43 correlates with human atrial conduction properties
    • Kanagaratnam P, Rothery S, Patel P, Severs NJ, Peters NS. Relative expression of immunolocalized connexins 40 and 43 correlates with human atrial conduction properties. J Am Coll Cardiol 2002;39:116-123.
    • (2002) J Am Coll Cardiol , vol.39 , pp. 116-123
    • Kanagaratnam, P.1    Rothery, S.2    Patel, P.3    Severs, N.J.4    Peters, N.S.5
  • 37
    • 0000566378 scopus 로고    scopus 로고
    • Normal and abnormal conduction in the heart
    • The Heart American Physiological Society, Oxford University Press
    • Kleber AG, Janse MJ, Fast VG. Normal and abnormal conduction in the heart. In: The Handbook of Physiology, The Cardiovascular System, Vol. 1. The Heart American Physiological Society, Oxford University Press; 2001. p455-529.
    • (2001) The Handbook of Physiology, the Cardiovascular System , vol.1 , pp. 455-529
    • Kleber, A.G.1    Janse, M.J.2    Fast, V.G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.