메뉴 건너뛰기




Volumn 69, Issue 3, 2014, Pages 296-303

Ecological risk assessment of the presence of pharmaceutical residues in a French national water survey

Author keywords

Environment; Pharmaceuticals; Risk assessment; Water resource

Indexed keywords

AMLODIPINE; AMOXICILLIN; ATENOLOL; CAFFEINE; CARBAMAZEPINE; CYCLOPHOSPHAMIDE; DICLOFENAC; DOXYCYCLINE; DRUG RESIDUE; ERYTHROMYCIN; ESTRADIOL; ESTRONE; FLUVOXAMINE; FUROSEMIDE; GADOLINIUM; HYDROCHLOROTHIAZIDE; IBUPROFEN; KETOPROFEN; LEVONORGESTREL; LOSARTAN; NAFTIDROFURYL; OXAZEPAM; PARACETAMOL; PRAVASTATIN; PROGESTERONE; RAMIPRIL; RANITIDINE; SALICYLIC ACID; TRIMETAZIDINE; UNINDEXED DRUG; DRUG; WATER; WATER POLLUTANT;

EID: 84904047702     PISSN: 02732300     EISSN: 10960295     Source Type: Journal    
DOI: 10.1016/j.yrtph.2014.04.006     Document Type: Article
Times cited : (118)

References (53)
  • 1
    • 0035987825 scopus 로고    scopus 로고
    • Carbamazepine in water: persistence in the environment, ozonation treatment and preliminary assessment on algal toxicity
    • Andreozzi R., Marotta R., Pinto G., Pollio A. Carbamazepine in water: persistence in the environment, ozonation treatment and preliminary assessment on algal toxicity. Water Res. 2002, 36(11):2869-2877.
    • (2002) Water Res. , vol.36 , Issue.11 , pp. 2869-2877
    • Andreozzi, R.1    Marotta, R.2    Pinto, G.3    Pollio, A.4
  • 2
    • 0037369490 scopus 로고    scopus 로고
    • Pharmaceuticals in STP effluents and their solar photodegradation in aquatic environment
    • Andreozzi R., Raffaele M., Nicklas P. Pharmaceuticals in STP effluents and their solar photodegradation in aquatic environment. Chemosphere 2003, 50(10):1319-1330.
    • (2003) Chemosphere , vol.50 , Issue.10 , pp. 1319-1330
    • Andreozzi, R.1    Raffaele, M.2    Nicklas, P.3
  • 3
    • 84904056823 scopus 로고    scopus 로고
    • ANSES, 2011. Campagne nationale d'occurrence des résidus de médicaments dans les eaux destinées à la consommation humaine. Available from: <>.
    • ANSES, 2011. Campagne nationale d'occurrence des résidus de médicaments dans les eaux destinées à la consommation humaine. Available from: <>. http://www.anses.fr/sites/default/files/documents/LABO-Ra-EtudeMedicamentsEaux.pdf.
  • 4
    • 48349095400 scopus 로고    scopus 로고
    • Exposure assessment of pharmaceuticals and their metabolites in the aquatic environment: application to the french situation and preliminary prioritization
    • Besse J.P., Kausch-Barreto C., Garric J. Exposure assessment of pharmaceuticals and their metabolites in the aquatic environment: application to the french situation and preliminary prioritization. Human Ecol. Risk Assess. 2008, 14:665-695.
    • (2008) Human Ecol. Risk Assess. , vol.14 , pp. 665-695
    • Besse, J.P.1    Kausch-Barreto, C.2    Garric, J.3
  • 5
    • 37549008799 scopus 로고    scopus 로고
    • Human pharmaceuticals in surface waters. Implementation of a prioritization methodology and application to the French situation
    • Besse J.P., Garric J. Human pharmaceuticals in surface waters. Implementation of a prioritization methodology and application to the French situation. Toxicol. Lett. 2008, 176(2):104-123.
    • (2008) Toxicol. Lett. , vol.176 , Issue.2 , pp. 104-123
    • Besse, J.P.1    Garric, J.2
  • 6
    • 33746612291 scopus 로고    scopus 로고
    • Predicted and measured concentrations for selected pharmaceuticals in UK rivers: implications for risk assessment
    • Bound J.P., Voulvoulis N. Predicted and measured concentrations for selected pharmaceuticals in UK rivers: implications for risk assessment. Water Res. 2006, 40(15):2885-2892.
    • (2006) Water Res. , vol.40 , Issue.15 , pp. 2885-2892
    • Bound, J.P.1    Voulvoulis, N.2
  • 7
    • 84873667768 scopus 로고    scopus 로고
    • Dilute concentrations of a psychiatric drug alter behavior of fish from natural populations
    • Brodin T., Fick J., Jonsson M., Klaminder J. Dilute concentrations of a psychiatric drug alter behavior of fish from natural populations. Science 2013, 339(6121):814-815.
    • (2013) Science , vol.339 , Issue.6121 , pp. 814-815
    • Brodin, T.1    Fick, J.2    Jonsson, M.3    Klaminder, J.4
  • 8
    • 0028029990 scopus 로고
    • Modelling of human acute toxicity from physicochemical properties and non-vertebrate acute toxicity of the 38 organic chemicals of the MEIC priority list by PLS regression and neural network
    • Calleja M.C., Geladi P., Persoone G. Modelling of human acute toxicity from physicochemical properties and non-vertebrate acute toxicity of the 38 organic chemicals of the MEIC priority list by PLS regression and neural network. Food Chem. Toxicol. 1994, 32(10):923-941.
    • (1994) Food Chem. Toxicol. , vol.32 , Issue.10 , pp. 923-941
    • Calleja, M.C.1    Geladi, P.2    Persoone, G.3
  • 9
    • 0028345560 scopus 로고
    • Human acute toxicity prediction of the first 50 MEIC chemicals by a battery of ecotoxicological tests and physicochemical properties
    • Calleja M.C., Persoone G., Geladi P. Human acute toxicity prediction of the first 50 MEIC chemicals by a battery of ecotoxicological tests and physicochemical properties. Food Chem. Toxicol. 1994, 32(2):173-187.
    • (1994) Food Chem. Toxicol. , vol.32 , Issue.2 , pp. 173-187
    • Calleja, M.C.1    Persoone, G.2    Geladi, P.3
  • 10
    • 33646853060 scopus 로고    scopus 로고
    • Are pharmaceuticals potent environmental pollutants? Part I: environmental risk assessments of selected active pharmaceutical ingredients
    • Carlsson C., Johansson A.K., Alvan G., Bergman K., Kühler T. Are pharmaceuticals potent environmental pollutants? Part I: environmental risk assessments of selected active pharmaceutical ingredients. Sci. Total Environ. 2006, 364(1-3):67-87.
    • (2006) Sci. Total Environ. , vol.364 , Issue.1-3 , pp. 67-87
    • Carlsson, C.1    Johansson, A.K.2    Alvan, G.3    Bergman, K.4    Kühler, T.5
  • 11
    • 52949084652 scopus 로고    scopus 로고
    • Seasonal variations of several pharmaceutical residues in surface water and sewage treatment plants of Han River, Korea
    • Choi K., Kim Y., Park J., Park C.K., Kim M., Kim H.S., Kim P. Seasonal variations of several pharmaceutical residues in surface water and sewage treatment plants of Han River, Korea. Sci. Total Environ. 2008, 405(1-3):120-128.
    • (2008) Sci. Total Environ. , vol.405 , Issue.1-3 , pp. 120-128
    • Choi, K.1    Kim, Y.2    Park, J.3    Park, C.K.4    Kim, M.5    Kim, H.S.6    Kim, P.7
  • 12
    • 40049101875 scopus 로고    scopus 로고
    • Rapid liquid chromatography-tandem mass spectrometry method for the determination of a broad mixture of pharmaceuticals in surface water
    • Conley J.M., Symes S.J., Kindelberger S.A., Richards S.M. Rapid liquid chromatography-tandem mass spectrometry method for the determination of a broad mixture of pharmaceuticals in surface water. J. Chromatogr. A 2008, 1185(2):206-215.
    • (2008) J. Chromatogr. A , vol.1185 , Issue.2 , pp. 206-215
    • Conley, J.M.1    Symes, S.J.2    Kindelberger, S.A.3    Richards, S.M.4
  • 14
    • 62949122307 scopus 로고    scopus 로고
    • Developmental anomalies induced by a non-selective COX inhibitor (ibuprofen) in zebrafish (Danio rerio)
    • David A., Pancharatna K. Developmental anomalies induced by a non-selective COX inhibitor (ibuprofen) in zebrafish (Danio rerio). Environ. Toxicol. Pharmacol. 2009, 27(3):390-395.
    • (2009) Environ. Toxicol. Pharmacol. , vol.27 , Issue.3 , pp. 390-395
    • David, A.1    Pancharatna, K.2
  • 15
    • 70350238652 scopus 로고    scopus 로고
    • Effects of acetaminophen (acetaminophen) in the embryonic development of zebrafish, Danio rerio
    • David A., Pancharatna K. Effects of acetaminophen (acetaminophen) in the embryonic development of zebrafish, Danio rerio. J. Appl. Toxicol. 2009, 29(7):597-602.
    • (2009) J. Appl. Toxicol. , vol.29 , Issue.7 , pp. 597-602
    • David, A.1    Pancharatna, K.2
  • 17
    • 84904056825 scopus 로고    scopus 로고
    • EMA, 2006. European medicine agency guideline on the environmental risk assessment of medicinal products for human use (EMEA/CHMP/SWP/4447/00). Available from: <>.
    • EMA, 2006. European medicine agency guideline on the environmental risk assessment of medicinal products for human use (EMEA/CHMP/SWP/4447/00). Available from: <>. http://www.ema.europa.eu/ema/pages/includes/document/open_document.jsp?webContentId=WC500003978.
  • 18
    • 0035861516 scopus 로고    scopus 로고
    • Determination of drugs in surface water and wastewater samples by liquid chromatography-mass spectrometry: methods and preliminary results including toxicity studies with Vibrio fischeri
    • Farré M.L., Ferrer I., Ginebreda A., Figueras M., Olivella L., Tirapu L., Vilanova M., Barceló D. Determination of drugs in surface water and wastewater samples by liquid chromatography-mass spectrometry: methods and preliminary results including toxicity studies with Vibrio fischeri. J. Chromatogr. A 2001, 938(1-2):187-197.
    • (2001) J. Chromatogr. A , vol.938 , Issue.1-2 , pp. 187-197
    • Farré, M.L.1    Ferrer, I.2    Ginebreda, A.3    Figueras, M.4    Olivella, L.5    Tirapu, L.6    Vilanova, M.7    Barceló, D.8
  • 19
    • 84862798577 scopus 로고    scopus 로고
    • Carbamazepine, carbamazepine epoxide and dihydroxycarbamazepine sorption to soil and occurrence in a wastewater reuse site in Tunisia
    • Fenet H., Mathieu O., Mahjoub O., Li Z., Hillaire-Buys D., Casellas C., Gomez E. Carbamazepine, carbamazepine epoxide and dihydroxycarbamazepine sorption to soil and occurrence in a wastewater reuse site in Tunisia. Chemosphere 2012, 88(1):49-54.
    • (2012) Chemosphere , vol.88 , Issue.1 , pp. 49-54
    • Fenet, H.1    Mathieu, O.2    Mahjoub, O.3    Li, Z.4    Hillaire-Buys, D.5    Casellas, C.6    Gomez, E.7
  • 20
    • 0038544203 scopus 로고    scopus 로고
    • Ecotoxicological impact of pharmaceuticals found in treated wastewaters: study of carbamazepine, clofibric acid, and diclofenac
    • Ferrari B., Paxéus N., Lo Giudice R., Pollio A., Garric J. Ecotoxicological impact of pharmaceuticals found in treated wastewaters: study of carbamazepine, clofibric acid, and diclofenac. Ecotoxicol. Environ. Saf. 2003, 55(3):359-370.
    • (2003) Ecotoxicol. Environ. Saf. , vol.55 , Issue.3 , pp. 359-370
    • Ferrari, B.1    Paxéus, N.2    Lo Giudice, R.3    Pollio, A.4    Garric, J.5
  • 21
    • 48649092025 scopus 로고    scopus 로고
    • A national reconnaissance for pharmaceuticals and other organic wastewater contaminants in the United States-II) untreated drinking water sources
    • Focazio M.J., Kolpin D.W., Barnes K.K., Furlong E.T., Meyer M.T., Zaugg S.D., Barber L.B., Thurman M.E. A national reconnaissance for pharmaceuticals and other organic wastewater contaminants in the United States-II) untreated drinking water sources. Sci. Total Environ. 2008, 402(2-3):201-216.
    • (2008) Sci. Total Environ. , vol.402 , Issue.2-3 , pp. 201-216
    • Focazio, M.J.1    Kolpin, D.W.2    Barnes, K.K.3    Furlong, E.T.4    Meyer, M.T.5    Zaugg, S.D.6    Barber, L.B.7    Thurman, M.E.8
  • 22
    • 84875829844 scopus 로고    scopus 로고
    • Chronic effects of exposure to a pharmaceutical mixture and municipal wastewater in zebrafish
    • Galus M., Jeyaranjaan J., Smith E., Li H., Metcalfe C., Wilson J.Y. Chronic effects of exposure to a pharmaceutical mixture and municipal wastewater in zebrafish. Aquat. Toxicol. 2013, 132-133(15):212-222.
    • (2013) Aquat. Toxicol. , Issue.15 , pp. 212-222
    • Galus, M.1    Jeyaranjaan, J.2    Smith, E.3    Li, H.4    Metcalfe, C.5    Wilson, J.Y.6
  • 25
    • 29744441163 scopus 로고    scopus 로고
    • Ecotoxicological risk of pharmaceuticals from wastewater treatment plants in Korea: occurrence and toxicity to Daphnia magna
    • Han G.H., Hur H.G., Kim S.D. Ecotoxicological risk of pharmaceuticals from wastewater treatment plants in Korea: occurrence and toxicity to Daphnia magna. Environ. Toxicol. Chem. 2006, 25(1):265-271.
    • (2006) Environ. Toxicol. Chem. , vol.25 , Issue.1 , pp. 265-271
    • Han, G.H.1    Hur, H.G.2    Kim, S.D.3
  • 26
    • 77953687759 scopus 로고    scopus 로고
    • Endocrine disruption and consequences of chronic exposure to ibuprofen in Japanese medaka (Oryzias latipes) and freshwater cladocerans Daphnia magna and Moina macrocopa
    • Han S., Choi K., Kim J., Ji K., Kim S., Ahn B., Yun J., Choi K., Khim J.S., Zhang X., Giesy J.P. Endocrine disruption and consequences of chronic exposure to ibuprofen in Japanese medaka (Oryzias latipes) and freshwater cladocerans Daphnia magna and Moina macrocopa. Aquat. Toxicol. 2010, 98(3):256-264.
    • (2010) Aquat. Toxicol. , vol.98 , Issue.3 , pp. 256-264
    • Han, S.1    Choi, K.2    Kim, J.3    Ji, K.4    Kim, S.5    Ahn, B.6    Yun, J.7    Choi, K.8    Khim, J.S.9    Zhang, X.10    Giesy, J.P.11
  • 27
    • 43349094325 scopus 로고    scopus 로고
    • Reproduction recovery of the crustacean Daphnia magna after chronic exposure to ibuprofen
    • Hayashi Y., Heckmann L.H., Callaghan A., Sibly R.M. Reproduction recovery of the crustacean Daphnia magna after chronic exposure to ibuprofen. Ecotoxicology 2008, 17(4):246-251.
    • (2008) Ecotoxicology , vol.17 , Issue.4 , pp. 246-251
    • Hayashi, Y.1    Heckmann, L.H.2    Callaghan, A.3    Sibly, R.M.4
  • 29
    • 84855461431 scopus 로고    scopus 로고
    • Assessment of the health risks related to the presence of drug residues in water for human consumption: application to carbamazepine
    • Houeto P., Carton A., Guerbet M., Mauclaire A.C., Gatignol C., Lechat P., Masset D. Assessment of the health risks related to the presence of drug residues in water for human consumption: application to carbamazepine. Regul. Toxicol. Pharmacol. 2012, 62(1):41-48.
    • (2012) Regul. Toxicol. Pharmacol. , vol.62 , Issue.1 , pp. 41-48
    • Houeto, P.1    Carton, A.2    Guerbet, M.3    Mauclaire, A.C.4    Gatignol, C.5    Lechat, P.6    Masset, D.7
  • 30
    • 77956341031 scopus 로고    scopus 로고
    • Toxicological effects of arsenate exposure on hematological, biochemical and liver transaminases activity in an Indian major carp, Catla catla
    • Kavitha C., Malarvizhi A., Senthil Kumaran S., Ramesh M. Toxicological effects of arsenate exposure on hematological, biochemical and liver transaminases activity in an Indian major carp, Catla catla. Food Chem. Toxicol. 2010, 48(10):2848-2854.
    • (2010) Food Chem. Toxicol. , vol.48 , Issue.10 , pp. 2848-2854
    • Kavitha, C.1    Malarvizhi, A.2    Senthil Kumaran, S.3    Ramesh, M.4
  • 31
    • 84863619420 scopus 로고    scopus 로고
    • Effect of chronic exposure to acetaminophen and lincomycin on Japanese medaka (Oryzias latipes) and freshwater cladocerans Daphnia magna and Moina macrocopa, and potential mechanisms of endocrine disruption
    • Kim P., Park Y., Ji K., Seo J., Lee S., Choi K., Kho Y., Park J., Choi K. Effect of chronic exposure to acetaminophen and lincomycin on Japanese medaka (Oryzias latipes) and freshwater cladocerans Daphnia magna and Moina macrocopa, and potential mechanisms of endocrine disruption. Chemosphere 2012, 89(1):10-18.
    • (2012) Chemosphere , vol.89 , Issue.1 , pp. 10-18
    • Kim, P.1    Park, Y.2    Ji, K.3    Seo, J.4    Lee, S.5    Choi, K.6    Kho, Y.7    Park, J.8    Choi, K.9
  • 34
    • 0024645192 scopus 로고
    • Results of the harmful effects of selected water polluants (anilines, phenols, aliphatic compounds) to Daphnia magna
    • Kuhn R., Pattard M. Results of the harmful effects of selected water polluants (anilines, phenols, aliphatic compounds) to Daphnia magna. Water Res. 1989, 23:495-499.
    • (1989) Water Res. , vol.23 , pp. 495-499
    • Kuhn, R.1    Pattard, M.2
  • 35
    • 4444241488 scopus 로고    scopus 로고
    • Resistance in the environment
    • Kummerer K. Resistance in the environment. J. Antimicrob. Chemother. 2004, 54(2):311-320.
    • (2004) J. Antimicrob. Chemother. , vol.54 , Issue.2 , pp. 311-320
    • Kummerer, K.1
  • 36
    • 78651437395 scopus 로고    scopus 로고
    • Transformation of the antiepileptic drug oxcarbazepine upon different water disinfection processes
    • Li Z., Fenet H., Gomez E., Chiron S. Transformation of the antiepileptic drug oxcarbazepine upon different water disinfection processes. Water Res. 2011, 45(4):1587-1596.
    • (2011) Water Res. , vol.45 , Issue.4 , pp. 1587-1596
    • Li, Z.1    Fenet, H.2    Gomez, E.3    Chiron, S.4
  • 37
    • 71549149009 scopus 로고    scopus 로고
    • Inhibition of egg production in zebrafish by fluoxetine and municipal effluents: a mechanistic evaluation
    • Lister A., Regan C., Van Zwol J., Van Der Kraak G. Inhibition of egg production in zebrafish by fluoxetine and municipal effluents: a mechanistic evaluation. Aquat. Toxicol. 2009, 95(4):320-329.
    • (2009) Aquat. Toxicol. , vol.95 , Issue.4 , pp. 320-329
    • Lister, A.1    Regan, C.2    Van Zwol, J.3    Van Der Kraak, G.4
  • 38
    • 79960465071 scopus 로고    scopus 로고
    • The toxicity potential of pharmaceuticals found in the Douro River estuary (Portugal): assessing impacts on gonadal maturation with a histopathological and stereological study of zebrafish ovary and testis after sub-acute exposures
    • Madureira T.V., Rocha M.J., Cruzeiro C., Galante M.H., Monteiro R.A., Rocha E. The toxicity potential of pharmaceuticals found in the Douro River estuary (Portugal): assessing impacts on gonadal maturation with a histopathological and stereological study of zebrafish ovary and testis after sub-acute exposures. Aquat. Toxicol. 2011, 105(3-4):292-299.
    • (2011) Aquat. Toxicol. , vol.105 , Issue.3-4 , pp. 292-299
    • Madureira, T.V.1    Rocha, M.J.2    Cruzeiro, C.3    Galante, M.H.4    Monteiro, R.A.5    Rocha, E.6
  • 41
    • 77950866871 scopus 로고    scopus 로고
    • In ovo nanoinjection of triclosan, diclofenac and carbamazepine affects embryonic development of medaka fish (Oryzias latipes)
    • Nassef M., Kim S.G., Seki M., Kang I.J., Hano T., Shimasaki Y., Oshima Y. In ovo nanoinjection of triclosan, diclofenac and carbamazepine affects embryonic development of medaka fish (Oryzias latipes). Chemosphere 2010, 79(9):966-973.
    • (2010) Chemosphere , vol.79 , Issue.9 , pp. 966-973
    • Nassef, M.1    Kim, S.G.2    Seki, M.3    Kang, I.J.4    Hano, T.5    Shimasaki, Y.6    Oshima, Y.7
  • 42
    • 33947729797 scopus 로고    scopus 로고
    • Occurrence and risk assessment of pharmaceutically active compounds in wastewater treatment plants. A case study: Seville city (Spain)
    • Santos J.L., Aparicio I., Alonso E. Occurrence and risk assessment of pharmaceutically active compounds in wastewater treatment plants. A case study: Seville city (Spain). Environ. Int. 2007, 33(4):596-601.
    • (2007) Environ. Int. , vol.33 , Issue.4 , pp. 596-601
    • Santos, J.L.1    Aparicio, I.2    Alonso, E.3
  • 43
    • 84857953821 scopus 로고    scopus 로고
    • Effects of Ibuprofen on hematological, biochemical and enzymological parameters of blood in an Indian major carp, Cirrhinus mrigala
    • Saravanan M., Devi K.U., Malarvizhi A., Ramesh M. Effects of Ibuprofen on hematological, biochemical and enzymological parameters of blood in an Indian major carp, Cirrhinus mrigala. Environ. Toxicol. Pharmacol. 2012, 34(1):14-22.
    • (2012) Environ. Toxicol. Pharmacol. , vol.34 , Issue.1 , pp. 14-22
    • Saravanan, M.1    Devi, K.U.2    Malarvizhi, A.3    Ramesh, M.4
  • 44
    • 84888008689 scopus 로고    scopus 로고
    • Alteration in certain enzymological parameters of an Indian major carp, Cirrhinus mrigala exposed to short- and long-term exposure of clofibric acid and diclofenac
    • Saravanan M., Ramesh M., Petkam R. Alteration in certain enzymological parameters of an Indian major carp, Cirrhinus mrigala exposed to short- and long-term exposure of clofibric acid and diclofenac. Fish Physiol. Biochem. 2013, 39(6):1431-1440.
    • (2013) Fish Physiol. Biochem. , vol.39 , Issue.6 , pp. 1431-1440
    • Saravanan, M.1    Ramesh, M.2    Petkam, R.3
  • 45
    • 3242680822 scopus 로고    scopus 로고
    • Persistence of pharmaceutical compounds and other organic wastewater contaminants in a conventional drinking-water-treatment plant
    • Stackelberg P.E., Furlong E.T., Meyer M.T., Zaugg S.D., Henderson A.K., Reissman D.B. Persistence of pharmaceutical compounds and other organic wastewater contaminants in a conventional drinking-water-treatment plant. Sci. Total Environ. 2004, 329(1-3):99-113.
    • (2004) Sci. Total Environ. , vol.329 , Issue.1-3 , pp. 99-113
    • Stackelberg, P.E.1    Furlong, E.T.2    Meyer, M.T.3    Zaugg, S.D.4    Henderson, A.K.5    Reissman, D.B.6
  • 46
    • 70049109606 scopus 로고    scopus 로고
    • Effects of various propolis concentrations on biochemical and hematological parameters of rainbow trout (Oncorhynchus mykiss)
    • Talas Z.S., Gulhan M.F. Effects of various propolis concentrations on biochemical and hematological parameters of rainbow trout (Oncorhynchus mykiss). Ecotoxicol. Environ. Saf. 2009, 72(7):1994-1998.
    • (2009) Ecotoxicol. Environ. Saf. , vol.72 , Issue.7 , pp. 1994-1998
    • Talas, Z.S.1    Gulhan, M.F.2
  • 47
    • 0037445163 scopus 로고    scopus 로고
    • Occurrence and fate of carbamazepine, clofibric acid, diclofenac, ibuprofen, ketoprofen, and naproxen in surface waters
    • Tixier C., Singer H.P., Oellers S., Müller S.R. Occurrence and fate of carbamazepine, clofibric acid, diclofenac, ibuprofen, ketoprofen, and naproxen in surface waters. Environ. Sci. Technol. 2003, 37(6):1061-1068.
    • (2003) Environ. Sci. Technol. , vol.37 , Issue.6 , pp. 1061-1068
    • Tixier, C.1    Singer, H.P.2    Oellers, S.3    Müller, S.R.4
  • 48
    • 2442535152 scopus 로고    scopus 로고
    • Toxic effects of the non-steroidal anti-inflammatory drug diclofenac. Part II: cytological effects in liver, kidney, gills and intestine of rainbow trout (Oncorhynchus mykiss)
    • Triebskorn R., Casper H., Heyd A., Eikemper R., Köhler H.R., Schwaiger J. Toxic effects of the non-steroidal anti-inflammatory drug diclofenac. Part II: cytological effects in liver, kidney, gills and intestine of rainbow trout (Oncorhynchus mykiss). Aquat. Toxicol. 2004, 68(2):151-166.
    • (2004) Aquat. Toxicol. , vol.68 , Issue.2 , pp. 151-166
    • Triebskorn, R.1    Casper, H.2    Heyd, A.3    Eikemper, R.4    Köhler, H.R.5    Schwaiger, J.6
  • 49
    • 33846880516 scopus 로고    scopus 로고
    • Ultrastructural effects of pharmaceuticals (carbamazepine, clofibric acid, metoprolol, diclofenac) in rainbow trout (Oncorhynchus mykiss) and common carp (Cyprinus carpio)
    • Triebskorn R., Casper H., Scheil V., Schwaiger J. Ultrastructural effects of pharmaceuticals (carbamazepine, clofibric acid, metoprolol, diclofenac) in rainbow trout (Oncorhynchus mykiss) and common carp (Cyprinus carpio). Anal. Bioanal. Chem. 2007, 387(4):1405-1416.
    • (2007) Anal. Bioanal. Chem. , vol.387 , Issue.4 , pp. 1405-1416
    • Triebskorn, R.1    Casper, H.2    Scheil, V.3    Schwaiger, J.4
  • 51
    • 77957916105 scopus 로고    scopus 로고
    • Fish embryo toxicity of carbamazepine, diclofenac and metoprolol
    • Van den Brandhof E.J., Montforts M. Fish embryo toxicity of carbamazepine, diclofenac and metoprolol. Ecotoxicol. Environ. Saf. 2010, 73(8):1862-1866.
    • (2010) Ecotoxicol. Environ. Saf. , vol.73 , Issue.8 , pp. 1862-1866
    • Van den Brandhof, E.J.1    Montforts, M.2
  • 53
    • 84869886405 scopus 로고    scopus 로고
    • Seasonal variation of endocrine disrupting compounds, pharmaceuticals and personal care products in wastewater treatment plants
    • Yu Y., Wu L., Chang A.C. Seasonal variation of endocrine disrupting compounds, pharmaceuticals and personal care products in wastewater treatment plants. Sci. Total Environ. 2013, 442:310-316.
    • (2013) Sci. Total Environ. , vol.442 , pp. 310-316
    • Yu, Y.1    Wu, L.2    Chang, A.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.