Chronic, low concentration exposure to pharmaceuticals impacts multiple organ systems in zebrafish

Aquatic Toxicology

Volumn 132-133, Issue , 2013, Pages 200-211

  Galus, Michal ^a   Kirischian, Nina ^a   Higgins, Sarah ^a   Purdy, James ^a   Chow, Justin ^a   Rangaranjan, Sahaana ^a   Li, Hongxia ^b   Metcalfe, Chris ^b   Wilson, Joanna Y ^a  

^a MCMASTER UNIVERSITY   (Canada)

^b TRENT UNIVERSITY   (Canada)

Author keywords

ACE; Acetaminophen; Carbamazepine; CBZ; Development; GEM; Gemfibrozil; Reproduction; VEN; Venlafaxine

Indexed keywords

11 OXOTESTOSTERONE; CARBAMAZEPINE; ESTRADIOL; GEMFIBROZIL; PARACETAMOL; VENLAFAXINE;

APOPTOSIS; CONCENTRATION (COMPOSITION); DRUG; EFFLUENT; FISH; HISTOLOGY; MORTALITY; POLLUTION EFFECT; POLLUTION EXPOSURE; REPRODUCTIVE SUCCESS; WASTEWATER;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DEVELOPMENTAL DISORDER; DEVELOPMENTAL TOXICITY; DRUG CONCENTRATION; EMBRYO; EMBRYO DEVELOPMENT; EMBRYO MORTALITY; EMBRYOPATHY; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL HEALTH; ENVIRONMENTAL IMPACT; ESTRADIOL BLOOD LEVEL; FEMALE; FEMALE INFERTILITY; GRANULOSA CELL; HEALTH HAZARD; HISTOPATHOLOGY; KIDNEY PROXIMAL TUBULE; LIVER STRUCTURE; LONG TERM EXPOSURE; MALE; MOLECULAR DYNAMICS; NICK END LABELING; NONHUMAN; OOCYTE DEVELOPMENT; OVARY FOLLICLE ATRESIA; PRIORITY JOURNAL; REPRODUCTIVE TOXICITY; TESTOSTERONE BLOOD LEVEL; THECA CELL; ZEBRA FISH;

ANIMALS; CHROMATOGRAPHY, LIQUID; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG TOXICITY; EMBRYO, NONMAMMALIAN; ENVIRONMENTAL EXPOSURE; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; IN SITU NICK-END LABELING; MALE; REPRODUCTION; TANDEM MASS SPECTROMETRY; WATER POLLUTANTS, CHEMICAL; ZEBRAFISH;

DANIO RERIO;

EID: 84875833526     PISSN: 0166445X     EISSN: 18791514     Source Type: Journal    
DOI: 10.1016/j.aquatox.2012.12.021     Document Type: Article

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