Contrasting effects of α-synuclein and γ-synuclein on the phenotype of cysteine string protein α (CSPα) null mutant mice suggest distinct function of these proteins in neuronal synapses

Journal of Biological Chemistry

Volumn 287, Issue 53, 2012, Pages 44471-44477

  Ninkina, Natalia ^a,b   Peters, Owen M ^a   Connor Robson, Natalie ^a   Lytkina, Olga ^b   Sharfeddin, Essam ^a   Buchman, Vladimir L ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

^b INSTITUTE OF PHYSIOLOGICALLY ACTIVE COMPOUNDS   (Russian Federation)

Author keywords

[No Author keywords available]

Indexed keywords

C-TERMINAL DOMAINS; COMPLEX FORMATIONS; COMPLEX SEQUENCES; DIFFERENT MECHANISMS; FUNCTIONAL REDUNDANCY; IN-VIVO; LIPID BINDING; N-TERMINALS; NEURODEGENERATION; NEURONAL SYNAPSIS; NULL MUTANT; OVER-EXPRESSION; PRESYNAPTIC; STRUCTURAL SIMILARITY; SYNAPTIC VESICLE; SYNUCLEIN;

ACTIVATION ANALYSIS; AMINO ACIDS; CELL MEMBRANES; MAMMALS;

PROTEINS;

ALPHA SYNUCLEIN; CYSTEINE STRING PROTEIN; CYSTEINE STRING PROTEIN ALPHA; GAMMA SYNUCLEIN; SYNAPTOBREVIN 2; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; CYSTEINE STRING PROTEIN ALPHA GENE; GENE; IN VIVO STUDY; MOLECULAR DYNAMICS; MOUSE; NERVE DEGENERATION; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; SYNAPSE VESICLE;

ALPHA-SYNUCLEIN; ANIMALS; CELLS, CULTURED; FEMALE; GAMMA-SYNUCLEIN; HSP40 HEAT-SHOCK PROTEINS; HUMANS; MALE; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEURONS; PHENOTYPE; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; SYNAPSES; SYNAPTIC VESICLES; VESICLE-ASSOCIATED MEMBRANE PROTEIN 2;

MUS;

EID: 84871745200     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.422402     Document Type: Article

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