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Volumn 3, Issue 1, 2014, Pages 1-11

Ganoderma formosanum polysaccharides attenuate Th2 inflammation and airway hyperresponsiveness in a murine model of allergic asthma

Author keywords

Airway hyperresponsiveness; Allergic asthma; Ganoderma formosanum; Immunomodulation; Polysaccharides

Indexed keywords


EID: 84904003423     PISSN: None     EISSN: 21931801     Source Type: Journal    
DOI: 10.1186/2193-1801-3-297     Document Type: Article
Times cited : (10)

References (49)
  • 1
    • 6444222929 scopus 로고    scopus 로고
    • New drugs for asthma
    • Barnes PJ: New drugs for asthma. Nat Rev Drug Discov 2004, 3: 831-844.
    • (2004) Nat Rev Drug Discov , vol.3 , pp. 831-844
    • Barnes, P.J.1
  • 2
    • 0024445794 scopus 로고
    • The polyclonal and antigen-specific IgE and IgG subclass response of mice injected with ovalbumin in alum or complete Freund's adjuvant
    • Beck L, Spiegelberg HL: The polyclonal and antigen-specific IgE and IgG subclass response of mice injected with ovalbumin in alum or complete Freund's adjuvant. Cell Immunol 1989, 123: 1-8.
    • (1989) Cell Immunol , vol.123 , pp. 1-8
    • Beck, L.1    Spiegelberg, H.L.2
  • 4
    • 34548598182 scopus 로고    scopus 로고
    • Ganoderma lucidum and its pharmaceutically active compounds
    • Boh B, Berovic M, Zhang J, Zhi-Bin L: Ganoderma lucidumand its pharmaceutically active compounds. Biotechnol Annu Rev 2007, 13: 265-301.
    • (2007) Biotechnol Annu Rev , vol.13 , pp. 265-301
    • Boh, B.1    Berovic, M.2    Zhang, J.3    Zhi-Bin, L.4
  • 5
    • 84876903600 scopus 로고    scopus 로고
    • Update on allergy immunotherapy: American Academy of Allergy, Asthma & Immunology/European Academy of Allergy and Clinical Immunology/PRACTALL consensus report
    • Burks AW, Calderon MA, Casale T, Cox L, Demoly P, Jutel M, Nelson H, Akdis CA: Update on allergy immunotherapy: American Academy of Allergy, Asthma & Immunology/European Academy of Allergy and Clinical Immunology/PRACTALL consensus report. J Allergy Clin Immunol 2013, 131(1288-1296): e1283.
    • (2013) J Allergy Clin Immunol , vol.131 , Issue.1288-1296
    • Burks, A.W.1    Calderon, M.A.2    Casale, T.3    Cox, L.4    Demoly, P.5    Jutel, M.6    Nelson, H.7    Akdis, C.A.8
  • 6
    • 84880087432 scopus 로고    scopus 로고
    • A nebulized complex traditional Chinese medicine inhibits Histamine and IL-4 production by ovalbumin in guinea pigs and can stabilize mast cells in vitro
    • Chang HC, Gong CC, Chan CL, Mak OT: A nebulized complex traditional Chinese medicine inhibits Histamine and IL-4 production by ovalbumin in guinea pigs and can stabilize mast cells in vitro. BMC Complement Altern Med 2013, 13: 174.
    • (2013) BMC Complement Altern Med , vol.13 , pp. 174
    • Chang, H.C.1    Gong, C.C.2    Chan, C.L.3    Mak, O.T.4
  • 7
    • 80053173744 scopus 로고    scopus 로고
    • Inhibitory effects of inhaled complex traditional Chinese medicine on early and late asthmatic responses induced by ovalbumin in sensitized guinea pigs
    • Chang HC, Gong CC, Chen JL, Mak OT: Inhibitory effects of inhaled complex traditional Chinese medicine on early and late asthmatic responses induced by ovalbumin in sensitized guinea pigs. BMC Complement Altern Med 2011, 11: 80.
    • (2011) BMC Complement Altern Med , vol.11 , pp. 80
    • Chang, H.C.1    Gong, C.C.2    Chen, J.L.3    Mak, O.T.4
  • 8
    • 34247217191 scopus 로고    scopus 로고
    • Effects of triterpenoid-rich extracts of Ganoderma tsugae on airway hyperreactivity and Th2 responses in vivo
    • Chen ML, Lin BF: Effects of triterpenoid-rich extracts ofGanoderma tsugaeon airway hyperreactivity and Th2 responses in vivo. Int Arch Allergy Immunol 2007, 143: 21-30.
    • (2007) Int Arch Allergy Immunol , vol.143 , pp. 21-30
    • Chen, M.L.1    Lin, B.F.2
  • 10
    • 80255135644 scopus 로고    scopus 로고
    • Allergen immunotherapy: a history of the first 100 years
    • Fitzhugh DJ, Lockey RF: Allergen immunotherapy: a history of the first 100 years. Curr Opin Allergy Clin Immunol 2011, 11: 554-559.
    • (2011) Curr Opin Allergy Clin Immunol , vol.11 , pp. 554-559
    • Fitzhugh, D.J.1    Lockey, R.F.2
  • 11
    • 61749093073 scopus 로고    scopus 로고
    • Use of CpG oligonucleotides in treatment of asthma and allergic disease
    • Fonseca DE, Kline JN: Use of CpG oligonucleotides in treatment of asthma and allergic disease. Adv Drug Deliv Rev 2009, 61: 256-262.
    • (2009) Adv Drug Deliv Rev , vol.61 , pp. 256-262
    • Fonseca, D.E.1    Kline, J.N.2
  • 12
    • 47949107183 scopus 로고    scopus 로고
    • The development of allergic inflammation
    • Galli SJ, Tsai M, Piliponsky AM: The development of allergic inflammation. Nature 2008, 454: 445-454.
    • (2008) Nature , vol.454 , pp. 445-454
    • Galli, S.J.1    Tsai, M.2    Piliponsky, A.M.3
  • 13
    • 67651162340 scopus 로고    scopus 로고
    • Immunobiology of asthma
    • Hamid Q, Tulic M: Immunobiology of asthma. Annu Rev Physiol 2009, 71: 489-507.
    • (2009) Annu Rev Physiol , vol.71 , pp. 489-507
    • Hamid, Q.1    Tulic, M.2
  • 16
    • 84866296348 scopus 로고    scopus 로고
    • Immunomodulatory effect of water soluble extract separated from mycelium of Phellinus linteus on experimental atopic dermatitis
    • Hwang JS, Kwon HK, Kim JE, Rho J, Im SH: Immunomodulatory effect of water soluble extract separated from mycelium of Phellinus linteus on experimental atopic dermatitis. BMC Complement Altern Med 2012, 12: 159.
    • (2012) BMC Complement Altern Med , vol.12 , pp. 159
    • Hwang, J.S.1    Kwon, H.K.2    Kim, J.E.3    Rho, J.4    Im, S.H.5
  • 17
    • 84869100349 scopus 로고    scopus 로고
    • IL-13 in asthma and allergic disease: asthma phenotypes and targeted therapies
    • Ingram JL, Kraft M: IL-13 in asthma and allergic disease: asthma phenotypes and targeted therapies. J Allergy Clin Immunol 2012, 130: 829-842.
    • (2012) J Allergy Clin Immunol , vol.130 , pp. 829-842
    • Ingram, J.L.1    Kraft, M.2
  • 19
    • 80053583835 scopus 로고    scopus 로고
    • Immuno-modulatory activity of Ganoderma lucidum-derived polysacharide on human monocytoid dendritic cells pulsed with Der p 1 allergen
    • Jan RH, Lin TY, Hsu YC, Lee SS, Lo SY, Chang M, Chen LK, Lin YL: Immuno-modulatory activity ofGanoderma lucidum-derived polysacharide on human monocytoid dendritic cells pulsed with Der p 1 allergen. BMC Immunol 2011, 12: 31.
    • (2011) BMC Immunol , vol.12 , pp. 31
    • Jan, R.H.1    Lin, T.Y.2    Hsu, Y.C.3    Lee, S.S.4    Lo, S.Y.5    Chang, M.6    Chen, L.K.7    Lin, Y.L.8
  • 20
    • 44749088349 scopus 로고    scopus 로고
    • Attenuating regulatory T cell induction by TLR agonists through inhibition of p38 MAPK signaling in dendritic cells enhances their efficacy as vaccine adjuvants and cancer immunotherapeutics
    • Jarnicki AG, Conroy H, Brereton C, Donnelly G, Toomey D, Walsh K, Sweeney C, Leavy O, Fletcher J, Lavelle EC, Dunne P, Mills KH: Attenuating regulatory T cell induction by TLR agonists through inhibition of p38 MAPK signaling in dendritic cells enhances their efficacy as vaccine adjuvants and cancer immunotherapeutics. J Immunol 2008, 180: 3797-3806.
    • (2008) J Immunol , vol.180 , pp. 3797-3806
    • Jarnicki, A.G.1    Conroy, H.2    Brereton, C.3    Donnelly, G.4    Toomey, D.5    Walsh, K.6    Sweeney, C.7    Leavy, O.8    Fletcher, J.9    Lavelle, E.C.10    Dunne, P.11    Mills, K.H.12
  • 21
    • 0029984358 scopus 로고    scopus 로고
    • CpG motifs present in bacteria DNA rapidly induce lymphocytes to secrete interleukin 6, interleukin 12, and interferon gamma
    • Klinman DM, Yi AK, Beaucage SL, Conover J, Krieg AM: CpG motifs present in bacteria DNA rapidly induce lymphocytes to secrete interleukin 6, interleukin 12, and interferon gamma. Proc Natl Acad Sci U S A 1996, 93: 2879-2883.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 2879-2883
    • Klinman, D.M.1    Yi, A.K.2    Beaucage, S.L.3    Conover, J.4    Krieg, A.M.5
  • 23
    • 78149395454 scopus 로고    scopus 로고
    • Shikonin inhibits maturation of bone marrow-derived dendritic cells and suppresses allergic airway inflammation in a murine model of asthma
    • Lee CC, Wang CN, Lai YT, Kang JJ, Liao JW, Chiang BL, Chen HC, Cheng YW: Shikonin inhibits maturation of bone marrow-derived dendritic cells and suppresses allergic airway inflammation in a murine model of asthma. Br J Pharmacol 2010, 161: 1496-1511.
    • (2010) Br J Pharmacol , vol.161 , pp. 1496-1511
    • Lee, C.C.1    Wang, C.N.2    Lai, Y.T.3    Kang, J.J.4    Liao, J.W.5    Chiang, B.L.6    Chen, H.C.7    Cheng, Y.W.8
  • 24
    • 84870978947 scopus 로고    scopus 로고
    • A water extract of Samchulkunbi-tang attenuates airway inflammation by inhibiting inos and MMP-9 activities in an ovalbumin-induced murine asthma model
    • Lee MY, Shin IS, Lim HS, Shin HK: A water extract of Samchulkunbi-tang attenuates airway inflammation by inhibiting inos and MMP-9 activities in an ovalbumin-induced murine asthma model. BMC Complement Altern Med 2012, 12: 257.
    • (2012) BMC Complement Altern Med , vol.12 , pp. 257
    • Lee, M.Y.1    Shin, I.S.2    Lim, H.S.3    Shin, H.K.4
  • 25
    • 17144473096 scopus 로고    scopus 로고
    • Hazardous air pollutants and asthma
    • Leikauf GD: Hazardous air pollutants and asthma. Environ Health Perspect 2002, 110(Suppl 4): 505-526.
    • (2002) Environ Health Perspect , vol.110 , Issue.SUPPL. 4 , pp. 505-526
    • Leikauf, G.D.1
  • 26
    • 81055144464 scopus 로고    scopus 로고
    • Recent status and prospects of the fungal immunomodulatory protein family
    • Li QZ, Wang XF, Zhou XW: Recent status and prospects of the fungal immunomodulatory protein family. Crit Rev Biotechnol 2011, 31: 365-375.
    • (2011) Crit Rev Biotechnol , vol.31 , pp. 365-375
    • Li, Q.Z.1    Wang, X.F.2    Zhou, X.W.3
  • 27
    • 30144439222 scopus 로고    scopus 로고
    • Ganoderma tsugae supplementation alleviates bronchoalveolar inflammation in an airway sensitization and challenge mouse model
    • Lin JY, Chen ML, Chiang BL, Lin BF: Ganoderma tsugaesupplementation alleviates bronchoalveolar inflammation in an airway sensitization and challenge mouse model. Int Immunopharmacol 2006, 6: 241-251.
    • (2006) Int Immunopharmacol , vol.6 , pp. 241-251
    • Lin, J.Y.1    Chen, M.L.2    Chiang, B.L.3    Lin, B.F.4
  • 28
    • 75949100823 scopus 로고    scopus 로고
    • Administration of polysaccharides from Antrodia camphorata modulates dendritic cell function and alleviates allergen-induced T helper type 2 responses in a mouse model of asthma
    • Liu KJ, Leu SJ, Su CH, Chiang BL, Chen YL, Lee YL: Administration of polysaccharides from Antrodia camphorata modulates dendritic cell function and alleviates allergen-induced T helper type 2 responses in a mouse model of asthma. Immunology 2010, 129: 351-362.
    • (2010) Immunology , vol.129 , pp. 351-362
    • Liu, K.J.1    Leu, S.J.2    Su, C.H.3    Chiang, B.L.4    Chen, Y.L.5    Lee, Y.L.6
  • 29
    • 0347024380 scopus 로고    scopus 로고
    • Effectiveness of Dp2 nasal therapy for Dp2- induced airway inflammation in mice: using oral Ganoderma lucidum as an immunomodulator
    • Liu YH, Tsai CF, Kao MC, Lai YL, Tsai JJ: Effectiveness of Dp2 nasal therapy for Dp2- induced airway inflammation in mice: using oralGanoderma lucidumas an immunomodulator. J Microbiol Immunol Infect 2003, 36: 236-242.
    • (2003) J Microbiol Immunol Infect , vol.36 , pp. 236-242
    • Liu, Y.H.1    Tsai, C.F.2    Kao, M.C.3    Lai, Y.L.4    Tsai, J.J.5
  • 30
    • 0033938275 scopus 로고    scopus 로고
    • Systemic or mucosal administration of immunostimulatory DNA inhibits early and late phases of murine allergic conjunctivitis
    • Magone MT, Chan CC, Beck L, Whitcup SM, Raz E: Systemic or mucosal administration of immunostimulatory DNA inhibits early and late phases of murine allergic conjunctivitis. Eur J Immunol 2000, 30: 1841-1850.
    • (2000) Eur J Immunol , vol.30 , pp. 1841-1850
    • Magone, M.T.1    Chan, C.C.2    Beck, L.3    Whitcup, S.M.4    Raz, E.5
  • 31
    • 59449093011 scopus 로고    scopus 로고
    • Complementary and alternative medicine: herbs, phytochemicals and vitamins and their immunologic effects
    • Mainardi T, Kapoor S, Bielory L: Complementary and alternative medicine: herbs, phytochemicals and vitamins and their immunologic effects. J Allergy Clin Immunol 2009, 123: 283-294.
    • (2009) J Allergy Clin Immunol , vol.123 , pp. 283-294
    • Mainardi, T.1    Kapoor, S.2    Bielory, L.3
  • 32
    • 33748091693 scopus 로고    scopus 로고
    • Ganoderma - a therapeutic fungal biofactory
    • Paterson RR: Ganoderma- a therapeutic fungal biofactory. Phytochemistry 2006, 67: 1985-2001.
    • (2006) Phytochemistry , vol.67 , pp. 1985-2001
    • Paterson, R.R.1
  • 33
    • 84870821942 scopus 로고    scopus 로고
    • The potential of biologics for the treatment of asthma
    • Pelaia G, Vatrella A, Maselli R: The potential of biologics for the treatment of asthma. Nat Rev Drug Discov 2012, 11: 958-972.
    • (2012) Nat Rev Drug Discov , vol.11 , pp. 958-972
    • Pelaia, G.1    Vatrella, A.2    Maselli, R.3
  • 34
    • 84891032934 scopus 로고    scopus 로고
    • Polysaccharides from Ganoderma formosanum function as a Th1 adjuvant and stimulate cytotoxic T cell response in vivo
    • Pi CC, Chu CL, Lu CY, Zhuang YJ, Wang CL, Yu YH, Wang HY, Lin CC, Chen CJ: Polysaccharides from Ganoderma formosanum function as a Th1 adjuvant and stimulate cytotoxic T cell response in vivo. Vaccine 2014, 32: 401-408.
    • (2014) Vaccine , vol.32 , pp. 401-408
    • Pi, C.C.1    Chu, C.L.2    Lu, C.Y.3    Zhuang, Y.J.4    Wang, C.L.5    Yu, Y.H.6    Wang, H.Y.7    Lin, C.C.8    Chen, C.J.9
  • 35
    • 78349268770 scopus 로고    scopus 로고
    • Immunomodulatory dietary polysaccharides: a systematic review of the literature
    • Ramberg JE, Nelson ED, Sinnott RA: Immunomodulatory dietary polysaccharides: a systematic review of the literature. Nutr J 2010, 9: 54.
    • (2010) Nutr J , vol.9 , pp. 54
    • Ramberg, J.E.1    Nelson, E.D.2    Sinnott, R.A.3
  • 36
    • 84883631190 scopus 로고    scopus 로고
    • Ovatodiolide inhibits the maturation of allergen-induced bone marrow-derived dendritic cells and induction of Th2 cell differentiation
    • Rao YK, Chen YC, Fang SH, Lai CH, Geethangili M, Lee CC, Tzeng YM: Ovatodiolide inhibits the maturation of allergen-induced bone marrow-derived dendritic cells and induction of Th2 cell differentiation. Int Immunopharmacol 2013, 17: 617-624.
    • (2013) Int Immunopharmacol , vol.17 , pp. 617-624
    • Rao, Y.K.1    Chen, Y.C.2    Fang, S.H.3    Lai, C.H.4    Geethangili, M.5    Lee, C.C.6    Tzeng, Y.M.7
  • 37
  • 38
    • 78649673636 scopus 로고    scopus 로고
    • Efficacy and safety of subcutaneous omalizumab vs placebo as add-on therapy to corticosteroids for children and adults with asthma: a systematic review
    • Rodrigo GJ, Neffen H, Castro-Rodriguez JA: Efficacy and safety of subcutaneous omalizumab vs placebo as add-on therapy to corticosteroids for children and adults with asthma: a systematic review. Chest 2011, 139: 28-35.
    • (2011) Chest , vol.139 , pp. 28-35
    • Rodrigo, G.J.1    Neffen, H.2    Castro-Rodriguez, J.A.3
  • 39
    • 0034493299 scopus 로고    scopus 로고
    • Animal models of bronchial asthma
    • Szelenyi I: Animal models of bronchial asthma. Inflamm Res 2000, 49: 639-654.
    • (2000) Inflamm Res , vol.49 , pp. 639-654
    • Szelenyi, I.1
  • 40
    • 84881351958 scopus 로고    scopus 로고
    • Profile of reslizumab in eosinophilic disease and its potential in the treatment of poorly controlled eosinophilic asthma
    • Walsh GM: Profile of reslizumab in eosinophilic disease and its potential in the treatment of poorly controlled eosinophilic asthma. Biologics 2013, 7: 7-11.
    • (2013) Biologics , vol.7 , pp. 7-11
    • Walsh, G.M.1
  • 41
    • 84879808796 scopus 로고    scopus 로고
    • Oral supplementation with areca-derived polyphenols attenuates food allergic responses in ovalbumin-sensitized mice
    • Wang CC, Lin YR, Liao MH, Jan TR: Oral supplementation with areca-derived polyphenols attenuates food allergic responses in ovalbumin-sensitized mice. BMC Complement Altern Med 2013, 13: 154.
    • (2013) BMC Complement Altern Med , vol.13 , pp. 154
    • Wang, C.C.1    Lin, Y.R.2    Liao, M.H.3    Jan, T.R.4
  • 42
    • 84864793205 scopus 로고    scopus 로고
    • Extracellular polysaccharides produced by Ganoderma formosanum stimulate macrophage activation via multiple pattern-recognition receptors
    • Wang CL, Lu CY, Pi CC, Zhuang YJ, Chu CL, Liu WH, Chen CJ: Extracellular polysaccharides produced byGanoderma formosanumstimulate macrophage activation via multiple pattern-recognition receptors. BMC Complement Altern Med 2012, 12: 119.
    • (2012) BMC Complement Altern Med , vol.12 , pp. 119
    • Wang, C.L.1    Lu, C.Y.2    Pi, C.C.3    Zhuang, Y.J.4    Chu, C.L.5    Liu, W.H.6    Chen, C.J.7
  • 43
    • 80053211038 scopus 로고    scopus 로고
    • Polysaccharides purified from the submerged culture of Ganoderma formosanum stimulate macrophage activation and protect mice against Listeria monocytogenes infection
    • Wang CL, Pi CC, Kuo CW, Zhuang YJ, Khoo KH, Liu WH, Chen CJ: Polysaccharides purified from the submerged culture ofGanoderma formosanumstimulate macrophage activation and protect mice againstListeria monocytogenesinfection. Biotechnol Lett 2011, 33: 2271-2278.
    • (2011) Biotechnol Lett , vol.33 , pp. 2271-2278
    • Wang, C.L.1    Pi, C.C.2    Kuo, C.W.3    Zhuang, Y.J.4    Khoo, K.H.5    Liu, W.H.6    Chen, C.J.7
  • 44
    • 0037210695 scopus 로고    scopus 로고
    • Medicinal mushrooms as a source of antitumor and immunomodulating polysaccharides
    • Wasser SP: Medicinal mushrooms as a source of antitumor and immunomodulating polysaccharides. Appl Microbiol Biotechnol 2002, 60: 258-274.
    • (2002) Appl Microbiol Biotechnol , vol.60 , pp. 258-274
    • Wasser, S.P.1
  • 45
    • 35348909044 scopus 로고    scopus 로고
    • Effect of an interleukin-4 variant on late phase asthmatic response to allergen challenge in asthmatic patients: results of two phase 2a studies
    • Wenzel S, Wilbraham D, Fuller R, Getz EB, Longphre M: Effect of an interleukin-4 variant on late phase asthmatic response to allergen challenge in asthmatic patients: results of two phase 2a studies. Lancet 2007, 370: 1422-1431.
    • (2007) Lancet , vol.370 , pp. 1422-1431
    • Wenzel, S.1    Wilbraham, D.2    Fuller, R.3    Getz, E.B.4    Longphre, M.5
  • 46
    • 0032968706 scopus 로고    scopus 로고
    • Immunologic basis of antigen-induced airway hyperresponsiveness
    • Wills-Karp M: Immunologic basis of antigen-induced airway hyperresponsiveness. Annu Rev Immunol 1999, 17: 255-281.
    • (1999) Annu Rev Immunol , vol.17 , pp. 255-281
    • Wills-Karp, M.1
  • 47
    • 78751493724 scopus 로고    scopus 로고
    • Ganoderma lucidum polysaccharides: immunomodulation and potential anti-tumor activities
    • Xu Z, Chen X, Zhong Z, Chen L, Wang Y: Ganoderma lucidumpolysaccharides: immunomodulation and potential anti-tumor activities. Am J Chin Med 2011, 39: 15-27.
    • (2011) Am J Chin Med , vol.39 , pp. 15-27
    • Xu, Z.1    Chen, X.2    Zhong, Z.3    Chen, L.4    Wang, Y.5
  • 48
    • 0031044958 scopus 로고    scopus 로고
    • Influence of the route of allergen administration and genetic background on the murine allergic pulmonary response
    • Zhang Y, Lamm WJ, Albert RK, Chi EY, Henderson WR Jr, Lewis DB: Influence of the route of allergen administration and genetic background on the murine allergic pulmonary response. Am J Respir Crit Care Med 1997, 155: 661-669.
    • (1997) Am J Respir Crit Care Med , vol.155 , pp. 661-669
    • Zhang, Y.1    Lamm, W.J.2    Albert, R.K.3    Chi, E.Y.4    Henderson Jr., W.R.5    Lewis, D.B.6
  • 49
    • 77952313777 scopus 로고    scopus 로고
    • Differentiation of effector CD4 T cell populations (*)
    • Zhu J, Yamane H, Paul WE: Differentiation of effector CD4 T cell populations (*). Annu Rev Immunol 2010, 28: 445-489.
    • (2010) Annu Rev Immunol , vol.28 , pp. 445-489
    • Zhu, J.1    Yamane, H.2    Paul, W.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.