-
1
-
-
34247866358
-
Human high-density lipoprotein particles prevent activation of the JNK pathway induced by human oxidised low-density lipoprotein particles in pancreatic beta cells
-
Abderrahmani A., Niederhauser G., Favre D. et al. (2007) Human high-density lipoprotein particles prevent activation of the JNK pathway induced by human oxidised low-density lipoprotein particles in pancreatic beta cells. Diabetologia 50, 1304-1314.
-
(2007)
Diabetologia
, vol.50
, pp. 1304-1314
-
-
Abderrahmani, A.1
Niederhauser, G.2
Favre, D.3
-
2
-
-
78751563884
-
Increased β-cell volume in mice fed a high-fat diet: a dynamic study over 12 months
-
Ahrén J., Ahrén B., Wierup N. (2010) Increased β-cell volume in mice fed a high-fat diet: a dynamic study over 12 months. Islets 2, 353-356.
-
(2010)
Islets
, vol.2
, pp. 353-356
-
-
Ahrén, J.1
Ahrén, B.2
Wierup, N.3
-
3
-
-
41949138132
-
ICER-1gamma overexpression drives palmitate-mediated connexin36 down-regulation in insulin-secreting cells
-
Allagnat F., Alonso F., Martin D., Abderrahmani A., Waeber G., Haefliger J.A. (2008) ICER-1gamma overexpression drives palmitate-mediated connexin36 down-regulation in insulin-secreting cells. J. Biol. Chem. 283, 5226-5234.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 5226-5234
-
-
Allagnat, F.1
Alonso, F.2
Martin, D.3
Abderrahmani, A.4
Waeber, G.5
Haefliger, J.A.6
-
4
-
-
77951603544
-
Improved insulin sensitivity in high fat- and high cholesterol-fed Ldlr-/- mice with macrophage-specific transgenic expression of cholesteryl ester hydrolase: role of macrophage inflammation and infiltration into adipose tissue
-
Bie J., Zhao B., Song J., Ghosh S. (2010) Improved insulin sensitivity in high fat- and high cholesterol-fed Ldlr-/- mice with macrophage-specific transgenic expression of cholesteryl ester hydrolase: role of macrophage inflammation and infiltration into adipose tissue. J. Biol. Chem. 285, 13630-13637.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 13630-13637
-
-
Bie, J.1
Zhao, B.2
Song, J.3
Ghosh, S.4
-
5
-
-
84856297712
-
LDL receptor knock-out mice are a physiological model particularly vulnerable to study the onset of inflammation in non-alcoholic fatty liver disease
-
Bieghs V., Van Gorp P.J., Wouters K. et al. (2012) LDL receptor knock-out mice are a physiological model particularly vulnerable to study the onset of inflammation in non-alcoholic fatty liver disease. PLoS ONE 7, e30668.
-
(2012)
PLoS ONE
, vol.7
-
-
Bieghs, V.1
Van Gorp, P.J.2
Wouters, K.3
-
6
-
-
73749088455
-
Primary hypercholesterolaemia impairs glucose homeostasis and insulin secretion in low-density lipoprotein receptor knockout mice independently of high-fat diet and obesity
-
Bonfleur M.L., Vanzela E.C., Ribeiro R.A. et al. (2010) Primary hypercholesterolaemia impairs glucose homeostasis and insulin secretion in low-density lipoprotein receptor knockout mice independently of high-fat diet and obesity. Biochim. Biophys. Acta 1801, 183-190.
-
(2010)
Biochim. Biophys. Acta
, vol.1801
, pp. 183-190
-
-
Bonfleur, M.L.1
Vanzela, E.C.2
Ribeiro, R.A.3
-
7
-
-
79960561698
-
Lower expression of PKAα impairs insulin secretion in islets isolated from low-density lipoprotein receptor (LDLR(-/-)) knockout mice
-
Bonfleur M.L., Ribeiro R.A., Balbo S.L. et al. (2011) Lower expression of PKAα impairs insulin secretion in islets isolated from low-density lipoprotein receptor (LDLR(-/-)) knockout mice. Metabolism 60, 1158-1164.
-
(2011)
Metabolism
, vol.60
, pp. 1158-1164
-
-
Bonfleur, M.L.1
Ribeiro, R.A.2
Balbo, S.L.3
-
8
-
-
33646554465
-
Histomorphology and ultrastructure of pancreatic islet tissue during in vivo maturation of rat pancreas
-
Carvalho C.P., Martins J.C., da Cunha D.A., Boschero A.C., Collares-Buzato C.B. (2006) Histomorphology and ultrastructure of pancreatic islet tissue during in vivo maturation of rat pancreas. Ann. Anat. 188, 221-234.
-
(2006)
Ann. Anat.
, vol.188
, pp. 221-234
-
-
Carvalho, C.P.1
Martins, J.C.2
da Cunha, D.A.3
Boschero, A.C.4
Collares-Buzato, C.B.5
-
9
-
-
77955653525
-
Beta cell coupling and connexin expression change during the functional maturation of rat pancreatic islets
-
Carvalho C.P., Barbosa H.C., Britan A. et al. (2010) Beta cell coupling and connexin expression change during the functional maturation of rat pancreatic islets. Diabetologia 53, 1428-1437.
-
(2010)
Diabetologia
, vol.53
, pp. 1428-1437
-
-
Carvalho, C.P.1
Barbosa, H.C.2
Britan, A.3
-
10
-
-
84863657669
-
Impaired β-cell-β-cell coupling mediated by Cx36 gap junctions in prediabetic mice
-
Carvalho C.P., Oliveira R.B., Britan A. et al. (2012) Impaired β-cell-β-cell coupling mediated by Cx36 gap junctions in prediabetic mice. Am. J. Physiol. Endocrinol. Metab. 303, E144-E151.
-
(2012)
Am. J. Physiol. Endocrinol. Metab.
, vol.303
-
-
Carvalho, C.P.1
Oliveira, R.B.2
Britan, A.3
-
11
-
-
34547645772
-
Obesity potentiates development of fatty liver and insulin resistance, but not atherosclerosis, in high-fat diet-fed agouti LDLR-deficient mice
-
Coenen K.R. & Hasty A.H. (2007) Obesity potentiates development of fatty liver and insulin resistance, but not atherosclerosis, in high-fat diet-fed agouti LDLR-deficient mice. Am. J. Physiol. Endocrinol. Metab. 293, E492-E499.
-
(2007)
Am. J. Physiol. Endocrinol. Metab.
, vol.293
-
-
Coenen, K.R.1
Hasty, A.H.2
-
12
-
-
64249150743
-
Age-accelerated atherosclerosis correlates with failure to upregulate antioxidant genes
-
Collins A.R., Lyon C.J., Xia X. et al. (2009) Age-accelerated atherosclerosis correlates with failure to upregulate antioxidant genes. Circ. Res. 104, e42-e54.
-
(2009)
Circ. Res.
, vol.104
-
-
Collins, A.R.1
Lyon, C.J.2
Xia, X.3
-
13
-
-
77951839161
-
Progression of diet-induced diabetes in C57BL6J mice involves functional dissociation of Ca2(+) channels from secretory vesicles
-
Collins S.C., Hoppa M.B., Walker J.N. et al. (2010) Progression of diet-induced diabetes in C57BL6J mice involves functional dissociation of Ca2(+) channels from secretory vesicles. Diabetes 59, 1192-1201.
-
(2010)
Diabetes
, vol.59
, pp. 1192-1201
-
-
Collins, S.C.1
Hoppa, M.B.2
Walker, J.N.3
-
14
-
-
70549113397
-
Role of glucotoxicity and lipotoxicity in the pathophysiology of Type 2 diabetes mellitus and emerging treatment strategies
-
Del Prato S. (2009) Role of glucotoxicity and lipotoxicity in the pathophysiology of Type 2 diabetes mellitus and emerging treatment strategies. Diabet. Med. 26, 1185-1192.
-
(2009)
Diabet. Med.
, vol.26
, pp. 1185-1192
-
-
Del Prato, S.1
-
15
-
-
76749091433
-
Glucose intolerance and decreased early insulin response in mice with severe hypertriglyceridemia
-
Ding Y.L., Wang Y.H., Huang W. et al. (2010) Glucose intolerance and decreased early insulin response in mice with severe hypertriglyceridemia. Exp. Biol. Med. (Maywood) 235, 40-46.
-
(2010)
Exp. Biol. Med. (Maywood)
, vol.235
, pp. 40-46
-
-
Ding, Y.L.1
Wang, Y.H.2
Huang, W.3
-
16
-
-
0034575220
-
Cholesterol-fed and transgenic rabbit models for the study of atherosclerosis
-
Fan J. & Watanabe T. (2000) Cholesterol-fed and transgenic rabbit models for the study of atherosclerosis. J. Atheroscler. Thromb. 7, 26-32.
-
(2000)
J. Atheroscler. Thromb.
, vol.7
, pp. 26-32
-
-
Fan, J.1
Watanabe, T.2
-
17
-
-
79251634527
-
Beta cell regeneration in human pancreas
-
Gianani R. (2011) Beta cell regeneration in human pancreas. Semin. Immunopathol. 33, 23-27.
-
(2011)
Semin. Immunopathol.
, vol.33
, pp. 23-27
-
-
Gianani, R.1
-
18
-
-
84863197999
-
Connexin-36 gap junctions regulate in vivo first- and second-phase insulin secretion dynamics and glucose tolerance in the conscious mouse
-
Head W.S., Orseth M.L., Nunemaker C.S., Satin L.S., Piston D.W., Benninger R.K. (2012) Connexin-36 gap junctions regulate in vivo first- and second-phase insulin secretion dynamics and glucose tolerance in the conscious mouse. Diabetes 61, 1700-1707.
-
(2012)
Diabetes
, vol.61
, pp. 1700-1707
-
-
Head, W.S.1
Orseth, M.L.2
Nunemaker, C.S.3
Satin, L.S.4
Piston, D.W.5
Benninger, R.K.6
-
19
-
-
0346100518
-
Scavenger receptors for oxidized and glycated proteins
-
Horiuchi S., Sakamoto Y., Sakai M. (2003) Scavenger receptors for oxidized and glycated proteins. Amino Acids 25, 283-292.
-
(2003)
Amino Acids
, vol.25
, pp. 283-292
-
-
Horiuchi, S.1
Sakamoto, Y.2
Sakai, M.3
-
20
-
-
14944359193
-
Correlation between volume fraction and volume-weighted mean volume, and between total number and total mass of islets in post-weaning and young Wistar rats
-
Inuwa I.M. & El Mardi A.S. (2005) Correlation between volume fraction and volume-weighted mean volume, and between total number and total mass of islets in post-weaning and young Wistar rats. J. Anat. 206, 185-192.
-
(2005)
J. Anat.
, vol.206
, pp. 185-192
-
-
Inuwa, I.M.1
El Mardi, A.S.2
-
21
-
-
0027258140
-
Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery
-
Ishibashi S., Brown M.S., Goldstein J.L., Gerard R.D., Hammer R.E., Herz J. (1993) Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery. J. Clin. Invest 92, 883-893.
-
(1993)
J. Clin. Invest
, vol.92
, pp. 883-893
-
-
Ishibashi, S.1
Brown, M.S.2
Goldstein, J.L.3
Gerard, R.D.4
Hammer, R.E.5
Herz, J.6
-
22
-
-
51749084429
-
Apolipoprotein E predisposes to obesity and related metabolic dysfunctions in mice
-
Karagiannides I., Abdou R., Tzortzopoulou A., Voshol P.J., Kypreos K.E. (2008) Apolipoprotein E predisposes to obesity and related metabolic dysfunctions in mice. FEBS J. 275, 4796-4809.
-
(2008)
FEBS J.
, vol.275
, pp. 4796-4809
-
-
Karagiannides, I.1
Abdou, R.2
Tzortzopoulou, A.3
Voshol, P.J.4
Kypreos, K.E.5
-
23
-
-
84055199884
-
Connexins protect mouse pancreatic β cells against apoptosis
-
Klee P., Allagnat F., Pontes H. et al. (2011a) Connexins protect mouse pancreatic β cells against apoptosis. J. Clin. Invest 121, 4870-4879.
-
(2011)
J. Clin. Invest
, vol.121
, pp. 4870-4879
-
-
Klee, P.1
Allagnat, F.2
Pontes, H.3
-
24
-
-
79960264237
-
Connexin implication in the control of the murine beta-cell mass
-
Klee P., Lamprianou S., Charollais A. et al. (2011b) Connexin implication in the control of the murine beta-cell mass. Pediatr. Res. 70, 142-147.
-
(2011)
Pediatr. Res.
, vol.70
, pp. 142-147
-
-
Klee, P.1
Lamprianou, S.2
Charollais, A.3
-
25
-
-
18944372249
-
Co-expression and regulation of connexins 36 and 43 in cultured neonatal rat pancreatic islets
-
Leite A.R., Carvalho C.P., Furtado A.G., Barbosa H.C., Boschero A.C., Collares-Buzato C.B. (2005) Co-expression and regulation of connexins 36 and 43 in cultured neonatal rat pancreatic islets. Can. J. Physiol. Pharmacol. 83, 142-151.
-
(2005)
Can. J. Physiol. Pharmacol.
, vol.83
, pp. 142-151
-
-
Leite, A.R.1
Carvalho, C.P.2
Furtado, A.G.3
Barbosa, H.C.4
Boschero, A.C.5
Collares-Buzato, C.B.6
-
26
-
-
0032936073
-
Western-type diets induce insulin resistance and hyperinsulinemia in LDL receptor-deficient mice but do not increase aortic atherosclerosis compared with normoinsulinemic mice in which similar plasma cholesterol levels are achieved by a fructose-rich diet
-
Merat S., Casanada F., Sutphin M., Palinski W., Reaven P.D. (1999) Western-type diets induce insulin resistance and hyperinsulinemia in LDL receptor-deficient mice but do not increase aortic atherosclerosis compared with normoinsulinemic mice in which similar plasma cholesterol levels are achieved by a fructose-rich diet. Arterioscler. Thromb. Vasc. Biol. 19, 1223-1230.
-
(1999)
Arterioscler. Thromb. Vasc. Biol.
, vol.19
, pp. 1223-1230
-
-
Merat, S.1
Casanada, F.2
Sutphin, M.3
Palinski, W.4
Reaven, P.D.5
-
27
-
-
73349120953
-
Pancreatic remodeling: beta-cell apoptosis, proliferation and neogenesis, and the measurement of beta-cell mass and of individual beta-cell size
-
Montanya E. & Téllez N. (2009) Pancreatic remodeling: beta-cell apoptosis, proliferation and neogenesis, and the measurement of beta-cell mass and of individual beta-cell size. Methods Mol. Biol. 560, 137-158.
-
(2009)
Methods Mol. Biol.
, vol.560
, pp. 137-158
-
-
Montanya, E.1
Téllez, N.2
-
28
-
-
12744274513
-
Fatty acid translocase (FAT/CD36) is localized on insulin-containing granules in human pancreatic beta-cells and mediates fatty acid effects on insulin secretion
-
Noushmehr H., D'Amico E., Farilla L. et al. (2005) Fatty acid translocase (FAT/CD36) is localized on insulin-containing granules in human pancreatic beta-cells and mediates fatty acid effects on insulin secretion. Diabetes 54, 472-481.
-
(2005)
Diabetes
, vol.54
, pp. 472-481
-
-
Noushmehr, H.1
D'Amico, E.2
Farilla, L.3
-
29
-
-
13644252970
-
Oxidized but not acetylated low-density lipoprotein reduces preproinsulin mRNA expression and secretion of insulin from HIT-T15 cells
-
Okajima F., Kurihara M., Ono C. et al. (2005) Oxidized but not acetylated low-density lipoprotein reduces preproinsulin mRNA expression and secretion of insulin from HIT-T15 cells. Biochim. Biophys. Acta 1687, 173-180.
-
(2005)
Biochim. Biophys. Acta
, vol.1687
, pp. 173-180
-
-
Okajima, F.1
Kurihara, M.2
Ono, C.3
-
30
-
-
0029097852
-
Increased autoantibody titers against epitopes of oxidized LDL in LDL receptor-deficient mice with increased atherosclerosis
-
Palinski W., Tangirala R.K., Miller E., Young S.G., Witztum J.L. (1995) Increased autoantibody titers against epitopes of oxidized LDL in LDL receptor-deficient mice with increased atherosclerosis. Arterioscler. Thromb. Vasc. Biol. 15, 1569-1576.
-
(1995)
Arterioscler. Thromb. Vasc. Biol.
, vol.15
, pp. 1569-1576
-
-
Palinski, W.1
Tangirala, R.K.2
Miller, E.3
Young, S.G.4
Witztum, J.L.5
-
31
-
-
77956373690
-
Beta-cell failure in diet-induced obese mice stratified according to body weight gain: secretory dysfunction and altered islet lipid metabolism without steatosis or reduced beta-cell mass
-
Peyot M.L., Pepin E., Lamontagne J. et al. (2010) Beta-cell failure in diet-induced obese mice stratified according to body weight gain: secretory dysfunction and altered islet lipid metabolism without steatosis or reduced beta-cell mass. Diabetes 59, 2178-2187.
-
(2010)
Diabetes
, vol.59
, pp. 2178-2187
-
-
Peyot, M.L.1
Pepin, E.2
Lamontagne, J.3
-
32
-
-
43549108142
-
Glucolipotoxicity: fuel excess and beta-cell dysfunction
-
Poitout V. & Robertson R.P. (2008) Glucolipotoxicity: fuel excess and beta-cell dysfunction. Endocr. Rev. 29, 351-366.
-
(2008)
Endocr. Rev.
, vol.29
, pp. 351-366
-
-
Poitout, V.1
Robertson, R.P.2
-
33
-
-
33745863033
-
Islet beta cell failure in type 2 diabetes
-
Prentki M. & Nolan C.J. (2006) Islet beta cell failure in type 2 diabetes. J. Clin. Invest 116, 1802-1812.
-
(2006)
J. Clin. Invest
, vol.116
, pp. 1802-1812
-
-
Prentki, M.1
Nolan, C.J.2
-
34
-
-
20044389102
-
Loss of connexin36 channels alters beta-cell coupling, islet synchronization of glucose-induced Ca2 + and insulin oscillations, and basal insulin release
-
Ravier M.A., Güldenagel M., Charollais A. et al. (2005) Loss of connexin36 channels alters beta-cell coupling, islet synchronization of glucose-induced Ca2 + and insulin oscillations, and basal insulin release. Diabetes 54, 1798-1807.
-
(2005)
Diabetes
, vol.54
, pp. 1798-1807
-
-
Ravier, M.A.1
Güldenagel, M.2
Charollais, A.3
-
35
-
-
12344323484
-
Type 2 diabetes-a matter of beta-cell life and death?
-
Rhodes C.J. (2005) Type 2 diabetes-a matter of beta-cell life and death? Science 307, 380-384.
-
(2005)
Science
, vol.307
, pp. 380-384
-
-
Rhodes, C.J.1
-
36
-
-
84863692697
-
Cell-to-cell contact dependence and junctional protein content are correlated with in vivo maturation of pancreatic beta cells
-
Santos-Silva J.C., Carvalho C.P., de Oliveira R.B., Boschero A.C., Collares-Buzato C.B. (2012) Cell-to-cell contact dependence and junctional protein content are correlated with in vivo maturation of pancreatic beta cells. Can. J. Physiol. Pharmacol. 90, 837-850.
-
(2012)
Can. J. Physiol. Pharmacol.
, vol.90
, pp. 837-850
-
-
Santos-Silva, J.C.1
Carvalho, C.P.2
de Oliveira, R.B.3
Boschero, A.C.4
Collares-Buzato, C.B.5
-
37
-
-
0030903840
-
Apoptosis participates in the remodeling of the endocrine pancreas in the neonatal rat
-
Scaglia L., Cahill C.J., Finegood D.T., Bonner-Weir S. (1997) Apoptosis participates in the remodeling of the endocrine pancreas in the neonatal rat. Endocrinology 138, 1736-1741.
-
(1997)
Endocrinology
, vol.138
, pp. 1736-1741
-
-
Scaglia, L.1
Cahill, C.J.2
Finegood, D.T.3
Bonner-Weir, S.4
-
38
-
-
0036076523
-
LDL receptor but not apolipoprotein E deficiency increases diet-induced obesity and diabetes in mice
-
Schreyer S.A., Vick C., Lystig T.C., Mystkowski P., LeBoeuf R.C. (2002) LDL receptor but not apolipoprotein E deficiency increases diet-induced obesity and diabetes in mice. Am. J. Physiol. Endocrinol. Metab. 282, E207-E214.
-
(2002)
Am. J. Physiol. Endocrinol. Metab.
, vol.282
-
-
Schreyer, S.A.1
Vick, C.2
Lystig, T.C.3
Mystkowski, P.4
LeBoeuf, R.C.5
-
39
-
-
58749115233
-
Cx36 makes channels coupling human pancreatic beta-cells, and correlates with insulin expression
-
Serre-Beinier V., Bosco D., Zulianello L. et al. (2009) Cx36 makes channels coupling human pancreatic beta-cells, and correlates with insulin expression. Hum. Mol. Genet. 18, 428-439.
-
(2009)
Hum. Mol. Genet.
, vol.18
, pp. 428-439
-
-
Serre-Beinier, V.1
Bosco, D.2
Zulianello, L.3
-
40
-
-
84873440296
-
Cholesterol reduction ameliorates glucose-induced calcium handling and insulin secretion in islets from low-density lipoprotein receptor knockout mice
-
Souza J.C., Vanzela E.C., Ribeiro R.A. et al. (2013) Cholesterol reduction ameliorates glucose-induced calcium handling and insulin secretion in islets from low-density lipoprotein receptor knockout mice. Biochim. Biophys. Acta 1831, 769-775.
-
(2013)
Biochim. Biophys. Acta
, vol.1831
, pp. 769-775
-
-
Souza, J.C.1
Vanzela, E.C.2
Ribeiro, R.A.3
-
41
-
-
80051826073
-
Dietary cholesterol exacerbates hepatic steatosis and inflammation in obese LDL receptor-deficient mice
-
Subramanian S., Goodspeed L., Wang S. et al. (2011) Dietary cholesterol exacerbates hepatic steatosis and inflammation in obese LDL receptor-deficient mice. J. Lipid Res. 52, 1626-1635.
-
(2011)
J. Lipid Res.
, vol.52
, pp. 1626-1635
-
-
Subramanian, S.1
Goodspeed, L.2
Wang, S.3
-
42
-
-
52049103091
-
Pancreas islets in metabolic signaling-focus on the beta-cell
-
Suckale J. & Solimena M. (2008) Pancreas islets in metabolic signaling-focus on the beta-cell. Front. Biosci. 13, 7156-7171.
-
(2008)
Front. Biosci.
, vol.13
, pp. 7156-7171
-
-
Suckale, J.1
Solimena, M.2
-
43
-
-
77956392948
-
Defects in insulin secretion and action in the pathogenesis of type 2 diabetes mellitus
-
Tripathy D. & Chavez A.O. (2010) Defects in insulin secretion and action in the pathogenesis of type 2 diabetes mellitus. Curr. Diab. Rep. 10, 184-191.
-
(2010)
Curr. Diab. Rep.
, vol.10
, pp. 184-191
-
-
Tripathy, D.1
Chavez, A.O.2
-
44
-
-
3543009434
-
The high-fat diet-fed mouse: a model for studying mechanisms and treatment of impaired glucose tolerance and type 2 diabetes
-
Winzell M.S. & Ahrén B. (2004) The high-fat diet-fed mouse: a model for studying mechanisms and treatment of impaired glucose tolerance and type 2 diabetes. Diabetes 53(Suppl 3), S215-S219.
-
(2004)
Diabetes
, vol.53
, Issue.Suppl 3
-
-
Winzell, M.S.1
Ahrén, B.2
|