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Volumn 95, Issue 4, 2014, Pages 296-308

Impaired compensatory beta-cell function and growth in response to high-fat diet in LDL receptor knockout mice

Author keywords

Beta cell mass; Connexin 36; High fat diet; LDL receptor; Prediabetes

Indexed keywords

CONNEXIN 36; GLUCOSE; HUMAN INSULIN; INSULIN; KI 67 ANTIGEN; LOW DENSITY LIPOPROTEIN RECEPTOR; RECOMBINANT HUMAN INSULIN;

EID: 84903984828     PISSN: 09599673     EISSN: 13652613     Source Type: Journal    
DOI: 10.1111/iep.12084     Document Type: Article
Times cited : (22)

References (44)
  • 1
    • 34247866358 scopus 로고    scopus 로고
    • Human high-density lipoprotein particles prevent activation of the JNK pathway induced by human oxidised low-density lipoprotein particles in pancreatic beta cells
    • Abderrahmani A., Niederhauser G., Favre D. et al. (2007) Human high-density lipoprotein particles prevent activation of the JNK pathway induced by human oxidised low-density lipoprotein particles in pancreatic beta cells. Diabetologia 50, 1304-1314.
    • (2007) Diabetologia , vol.50 , pp. 1304-1314
    • Abderrahmani, A.1    Niederhauser, G.2    Favre, D.3
  • 2
    • 78751563884 scopus 로고    scopus 로고
    • Increased β-cell volume in mice fed a high-fat diet: a dynamic study over 12 months
    • Ahrén J., Ahrén B., Wierup N. (2010) Increased β-cell volume in mice fed a high-fat diet: a dynamic study over 12 months. Islets 2, 353-356.
    • (2010) Islets , vol.2 , pp. 353-356
    • Ahrén, J.1    Ahrén, B.2    Wierup, N.3
  • 3
    • 41949138132 scopus 로고    scopus 로고
    • ICER-1gamma overexpression drives palmitate-mediated connexin36 down-regulation in insulin-secreting cells
    • Allagnat F., Alonso F., Martin D., Abderrahmani A., Waeber G., Haefliger J.A. (2008) ICER-1gamma overexpression drives palmitate-mediated connexin36 down-regulation in insulin-secreting cells. J. Biol. Chem. 283, 5226-5234.
    • (2008) J. Biol. Chem. , vol.283 , pp. 5226-5234
    • Allagnat, F.1    Alonso, F.2    Martin, D.3    Abderrahmani, A.4    Waeber, G.5    Haefliger, J.A.6
  • 4
    • 77951603544 scopus 로고    scopus 로고
    • Improved insulin sensitivity in high fat- and high cholesterol-fed Ldlr-/- mice with macrophage-specific transgenic expression of cholesteryl ester hydrolase: role of macrophage inflammation and infiltration into adipose tissue
    • Bie J., Zhao B., Song J., Ghosh S. (2010) Improved insulin sensitivity in high fat- and high cholesterol-fed Ldlr-/- mice with macrophage-specific transgenic expression of cholesteryl ester hydrolase: role of macrophage inflammation and infiltration into adipose tissue. J. Biol. Chem. 285, 13630-13637.
    • (2010) J. Biol. Chem. , vol.285 , pp. 13630-13637
    • Bie, J.1    Zhao, B.2    Song, J.3    Ghosh, S.4
  • 5
    • 84856297712 scopus 로고    scopus 로고
    • LDL receptor knock-out mice are a physiological model particularly vulnerable to study the onset of inflammation in non-alcoholic fatty liver disease
    • Bieghs V., Van Gorp P.J., Wouters K. et al. (2012) LDL receptor knock-out mice are a physiological model particularly vulnerable to study the onset of inflammation in non-alcoholic fatty liver disease. PLoS ONE 7, e30668.
    • (2012) PLoS ONE , vol.7
    • Bieghs, V.1    Van Gorp, P.J.2    Wouters, K.3
  • 6
    • 73749088455 scopus 로고    scopus 로고
    • Primary hypercholesterolaemia impairs glucose homeostasis and insulin secretion in low-density lipoprotein receptor knockout mice independently of high-fat diet and obesity
    • Bonfleur M.L., Vanzela E.C., Ribeiro R.A. et al. (2010) Primary hypercholesterolaemia impairs glucose homeostasis and insulin secretion in low-density lipoprotein receptor knockout mice independently of high-fat diet and obesity. Biochim. Biophys. Acta 1801, 183-190.
    • (2010) Biochim. Biophys. Acta , vol.1801 , pp. 183-190
    • Bonfleur, M.L.1    Vanzela, E.C.2    Ribeiro, R.A.3
  • 7
    • 79960561698 scopus 로고    scopus 로고
    • Lower expression of PKAα impairs insulin secretion in islets isolated from low-density lipoprotein receptor (LDLR(-/-)) knockout mice
    • Bonfleur M.L., Ribeiro R.A., Balbo S.L. et al. (2011) Lower expression of PKAα impairs insulin secretion in islets isolated from low-density lipoprotein receptor (LDLR(-/-)) knockout mice. Metabolism 60, 1158-1164.
    • (2011) Metabolism , vol.60 , pp. 1158-1164
    • Bonfleur, M.L.1    Ribeiro, R.A.2    Balbo, S.L.3
  • 8
    • 33646554465 scopus 로고    scopus 로고
    • Histomorphology and ultrastructure of pancreatic islet tissue during in vivo maturation of rat pancreas
    • Carvalho C.P., Martins J.C., da Cunha D.A., Boschero A.C., Collares-Buzato C.B. (2006) Histomorphology and ultrastructure of pancreatic islet tissue during in vivo maturation of rat pancreas. Ann. Anat. 188, 221-234.
    • (2006) Ann. Anat. , vol.188 , pp. 221-234
    • Carvalho, C.P.1    Martins, J.C.2    da Cunha, D.A.3    Boschero, A.C.4    Collares-Buzato, C.B.5
  • 9
    • 77955653525 scopus 로고    scopus 로고
    • Beta cell coupling and connexin expression change during the functional maturation of rat pancreatic islets
    • Carvalho C.P., Barbosa H.C., Britan A. et al. (2010) Beta cell coupling and connexin expression change during the functional maturation of rat pancreatic islets. Diabetologia 53, 1428-1437.
    • (2010) Diabetologia , vol.53 , pp. 1428-1437
    • Carvalho, C.P.1    Barbosa, H.C.2    Britan, A.3
  • 10
    • 84863657669 scopus 로고    scopus 로고
    • Impaired β-cell-β-cell coupling mediated by Cx36 gap junctions in prediabetic mice
    • Carvalho C.P., Oliveira R.B., Britan A. et al. (2012) Impaired β-cell-β-cell coupling mediated by Cx36 gap junctions in prediabetic mice. Am. J. Physiol. Endocrinol. Metab. 303, E144-E151.
    • (2012) Am. J. Physiol. Endocrinol. Metab. , vol.303
    • Carvalho, C.P.1    Oliveira, R.B.2    Britan, A.3
  • 11
    • 34547645772 scopus 로고    scopus 로고
    • Obesity potentiates development of fatty liver and insulin resistance, but not atherosclerosis, in high-fat diet-fed agouti LDLR-deficient mice
    • Coenen K.R. & Hasty A.H. (2007) Obesity potentiates development of fatty liver and insulin resistance, but not atherosclerosis, in high-fat diet-fed agouti LDLR-deficient mice. Am. J. Physiol. Endocrinol. Metab. 293, E492-E499.
    • (2007) Am. J. Physiol. Endocrinol. Metab. , vol.293
    • Coenen, K.R.1    Hasty, A.H.2
  • 12
    • 64249150743 scopus 로고    scopus 로고
    • Age-accelerated atherosclerosis correlates with failure to upregulate antioxidant genes
    • Collins A.R., Lyon C.J., Xia X. et al. (2009) Age-accelerated atherosclerosis correlates with failure to upregulate antioxidant genes. Circ. Res. 104, e42-e54.
    • (2009) Circ. Res. , vol.104
    • Collins, A.R.1    Lyon, C.J.2    Xia, X.3
  • 13
    • 77951839161 scopus 로고    scopus 로고
    • Progression of diet-induced diabetes in C57BL6J mice involves functional dissociation of Ca2(+) channels from secretory vesicles
    • Collins S.C., Hoppa M.B., Walker J.N. et al. (2010) Progression of diet-induced diabetes in C57BL6J mice involves functional dissociation of Ca2(+) channels from secretory vesicles. Diabetes 59, 1192-1201.
    • (2010) Diabetes , vol.59 , pp. 1192-1201
    • Collins, S.C.1    Hoppa, M.B.2    Walker, J.N.3
  • 14
    • 70549113397 scopus 로고    scopus 로고
    • Role of glucotoxicity and lipotoxicity in the pathophysiology of Type 2 diabetes mellitus and emerging treatment strategies
    • Del Prato S. (2009) Role of glucotoxicity and lipotoxicity in the pathophysiology of Type 2 diabetes mellitus and emerging treatment strategies. Diabet. Med. 26, 1185-1192.
    • (2009) Diabet. Med. , vol.26 , pp. 1185-1192
    • Del Prato, S.1
  • 15
    • 76749091433 scopus 로고    scopus 로고
    • Glucose intolerance and decreased early insulin response in mice with severe hypertriglyceridemia
    • Ding Y.L., Wang Y.H., Huang W. et al. (2010) Glucose intolerance and decreased early insulin response in mice with severe hypertriglyceridemia. Exp. Biol. Med. (Maywood) 235, 40-46.
    • (2010) Exp. Biol. Med. (Maywood) , vol.235 , pp. 40-46
    • Ding, Y.L.1    Wang, Y.H.2    Huang, W.3
  • 16
    • 0034575220 scopus 로고    scopus 로고
    • Cholesterol-fed and transgenic rabbit models for the study of atherosclerosis
    • Fan J. & Watanabe T. (2000) Cholesterol-fed and transgenic rabbit models for the study of atherosclerosis. J. Atheroscler. Thromb. 7, 26-32.
    • (2000) J. Atheroscler. Thromb. , vol.7 , pp. 26-32
    • Fan, J.1    Watanabe, T.2
  • 17
    • 79251634527 scopus 로고    scopus 로고
    • Beta cell regeneration in human pancreas
    • Gianani R. (2011) Beta cell regeneration in human pancreas. Semin. Immunopathol. 33, 23-27.
    • (2011) Semin. Immunopathol. , vol.33 , pp. 23-27
    • Gianani, R.1
  • 18
    • 84863197999 scopus 로고    scopus 로고
    • Connexin-36 gap junctions regulate in vivo first- and second-phase insulin secretion dynamics and glucose tolerance in the conscious mouse
    • Head W.S., Orseth M.L., Nunemaker C.S., Satin L.S., Piston D.W., Benninger R.K. (2012) Connexin-36 gap junctions regulate in vivo first- and second-phase insulin secretion dynamics and glucose tolerance in the conscious mouse. Diabetes 61, 1700-1707.
    • (2012) Diabetes , vol.61 , pp. 1700-1707
    • Head, W.S.1    Orseth, M.L.2    Nunemaker, C.S.3    Satin, L.S.4    Piston, D.W.5    Benninger, R.K.6
  • 19
    • 0346100518 scopus 로고    scopus 로고
    • Scavenger receptors for oxidized and glycated proteins
    • Horiuchi S., Sakamoto Y., Sakai M. (2003) Scavenger receptors for oxidized and glycated proteins. Amino Acids 25, 283-292.
    • (2003) Amino Acids , vol.25 , pp. 283-292
    • Horiuchi, S.1    Sakamoto, Y.2    Sakai, M.3
  • 20
    • 14944359193 scopus 로고    scopus 로고
    • Correlation between volume fraction and volume-weighted mean volume, and between total number and total mass of islets in post-weaning and young Wistar rats
    • Inuwa I.M. & El Mardi A.S. (2005) Correlation between volume fraction and volume-weighted mean volume, and between total number and total mass of islets in post-weaning and young Wistar rats. J. Anat. 206, 185-192.
    • (2005) J. Anat. , vol.206 , pp. 185-192
    • Inuwa, I.M.1    El Mardi, A.S.2
  • 21
    • 0027258140 scopus 로고
    • Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery
    • Ishibashi S., Brown M.S., Goldstein J.L., Gerard R.D., Hammer R.E., Herz J. (1993) Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery. J. Clin. Invest 92, 883-893.
    • (1993) J. Clin. Invest , vol.92 , pp. 883-893
    • Ishibashi, S.1    Brown, M.S.2    Goldstein, J.L.3    Gerard, R.D.4    Hammer, R.E.5    Herz, J.6
  • 22
    • 51749084429 scopus 로고    scopus 로고
    • Apolipoprotein E predisposes to obesity and related metabolic dysfunctions in mice
    • Karagiannides I., Abdou R., Tzortzopoulou A., Voshol P.J., Kypreos K.E. (2008) Apolipoprotein E predisposes to obesity and related metabolic dysfunctions in mice. FEBS J. 275, 4796-4809.
    • (2008) FEBS J. , vol.275 , pp. 4796-4809
    • Karagiannides, I.1    Abdou, R.2    Tzortzopoulou, A.3    Voshol, P.J.4    Kypreos, K.E.5
  • 23
    • 84055199884 scopus 로고    scopus 로고
    • Connexins protect mouse pancreatic β cells against apoptosis
    • Klee P., Allagnat F., Pontes H. et al. (2011a) Connexins protect mouse pancreatic β cells against apoptosis. J. Clin. Invest 121, 4870-4879.
    • (2011) J. Clin. Invest , vol.121 , pp. 4870-4879
    • Klee, P.1    Allagnat, F.2    Pontes, H.3
  • 24
    • 79960264237 scopus 로고    scopus 로고
    • Connexin implication in the control of the murine beta-cell mass
    • Klee P., Lamprianou S., Charollais A. et al. (2011b) Connexin implication in the control of the murine beta-cell mass. Pediatr. Res. 70, 142-147.
    • (2011) Pediatr. Res. , vol.70 , pp. 142-147
    • Klee, P.1    Lamprianou, S.2    Charollais, A.3
  • 26
    • 0032936073 scopus 로고    scopus 로고
    • Western-type diets induce insulin resistance and hyperinsulinemia in LDL receptor-deficient mice but do not increase aortic atherosclerosis compared with normoinsulinemic mice in which similar plasma cholesterol levels are achieved by a fructose-rich diet
    • Merat S., Casanada F., Sutphin M., Palinski W., Reaven P.D. (1999) Western-type diets induce insulin resistance and hyperinsulinemia in LDL receptor-deficient mice but do not increase aortic atherosclerosis compared with normoinsulinemic mice in which similar plasma cholesterol levels are achieved by a fructose-rich diet. Arterioscler. Thromb. Vasc. Biol. 19, 1223-1230.
    • (1999) Arterioscler. Thromb. Vasc. Biol. , vol.19 , pp. 1223-1230
    • Merat, S.1    Casanada, F.2    Sutphin, M.3    Palinski, W.4    Reaven, P.D.5
  • 27
    • 73349120953 scopus 로고    scopus 로고
    • Pancreatic remodeling: beta-cell apoptosis, proliferation and neogenesis, and the measurement of beta-cell mass and of individual beta-cell size
    • Montanya E. & Téllez N. (2009) Pancreatic remodeling: beta-cell apoptosis, proliferation and neogenesis, and the measurement of beta-cell mass and of individual beta-cell size. Methods Mol. Biol. 560, 137-158.
    • (2009) Methods Mol. Biol. , vol.560 , pp. 137-158
    • Montanya, E.1    Téllez, N.2
  • 28
    • 12744274513 scopus 로고    scopus 로고
    • Fatty acid translocase (FAT/CD36) is localized on insulin-containing granules in human pancreatic beta-cells and mediates fatty acid effects on insulin secretion
    • Noushmehr H., D'Amico E., Farilla L. et al. (2005) Fatty acid translocase (FAT/CD36) is localized on insulin-containing granules in human pancreatic beta-cells and mediates fatty acid effects on insulin secretion. Diabetes 54, 472-481.
    • (2005) Diabetes , vol.54 , pp. 472-481
    • Noushmehr, H.1    D'Amico, E.2    Farilla, L.3
  • 29
    • 13644252970 scopus 로고    scopus 로고
    • Oxidized but not acetylated low-density lipoprotein reduces preproinsulin mRNA expression and secretion of insulin from HIT-T15 cells
    • Okajima F., Kurihara M., Ono C. et al. (2005) Oxidized but not acetylated low-density lipoprotein reduces preproinsulin mRNA expression and secretion of insulin from HIT-T15 cells. Biochim. Biophys. Acta 1687, 173-180.
    • (2005) Biochim. Biophys. Acta , vol.1687 , pp. 173-180
    • Okajima, F.1    Kurihara, M.2    Ono, C.3
  • 30
    • 0029097852 scopus 로고
    • Increased autoantibody titers against epitopes of oxidized LDL in LDL receptor-deficient mice with increased atherosclerosis
    • Palinski W., Tangirala R.K., Miller E., Young S.G., Witztum J.L. (1995) Increased autoantibody titers against epitopes of oxidized LDL in LDL receptor-deficient mice with increased atherosclerosis. Arterioscler. Thromb. Vasc. Biol. 15, 1569-1576.
    • (1995) Arterioscler. Thromb. Vasc. Biol. , vol.15 , pp. 1569-1576
    • Palinski, W.1    Tangirala, R.K.2    Miller, E.3    Young, S.G.4    Witztum, J.L.5
  • 31
    • 77956373690 scopus 로고    scopus 로고
    • Beta-cell failure in diet-induced obese mice stratified according to body weight gain: secretory dysfunction and altered islet lipid metabolism without steatosis or reduced beta-cell mass
    • Peyot M.L., Pepin E., Lamontagne J. et al. (2010) Beta-cell failure in diet-induced obese mice stratified according to body weight gain: secretory dysfunction and altered islet lipid metabolism without steatosis or reduced beta-cell mass. Diabetes 59, 2178-2187.
    • (2010) Diabetes , vol.59 , pp. 2178-2187
    • Peyot, M.L.1    Pepin, E.2    Lamontagne, J.3
  • 32
    • 43549108142 scopus 로고    scopus 로고
    • Glucolipotoxicity: fuel excess and beta-cell dysfunction
    • Poitout V. & Robertson R.P. (2008) Glucolipotoxicity: fuel excess and beta-cell dysfunction. Endocr. Rev. 29, 351-366.
    • (2008) Endocr. Rev. , vol.29 , pp. 351-366
    • Poitout, V.1    Robertson, R.P.2
  • 33
    • 33745863033 scopus 로고    scopus 로고
    • Islet beta cell failure in type 2 diabetes
    • Prentki M. & Nolan C.J. (2006) Islet beta cell failure in type 2 diabetes. J. Clin. Invest 116, 1802-1812.
    • (2006) J. Clin. Invest , vol.116 , pp. 1802-1812
    • Prentki, M.1    Nolan, C.J.2
  • 34
    • 20044389102 scopus 로고    scopus 로고
    • Loss of connexin36 channels alters beta-cell coupling, islet synchronization of glucose-induced Ca2 + and insulin oscillations, and basal insulin release
    • Ravier M.A., Güldenagel M., Charollais A. et al. (2005) Loss of connexin36 channels alters beta-cell coupling, islet synchronization of glucose-induced Ca2 + and insulin oscillations, and basal insulin release. Diabetes 54, 1798-1807.
    • (2005) Diabetes , vol.54 , pp. 1798-1807
    • Ravier, M.A.1    Güldenagel, M.2    Charollais, A.3
  • 35
    • 12344323484 scopus 로고    scopus 로고
    • Type 2 diabetes-a matter of beta-cell life and death?
    • Rhodes C.J. (2005) Type 2 diabetes-a matter of beta-cell life and death? Science 307, 380-384.
    • (2005) Science , vol.307 , pp. 380-384
    • Rhodes, C.J.1
  • 37
    • 0030903840 scopus 로고    scopus 로고
    • Apoptosis participates in the remodeling of the endocrine pancreas in the neonatal rat
    • Scaglia L., Cahill C.J., Finegood D.T., Bonner-Weir S. (1997) Apoptosis participates in the remodeling of the endocrine pancreas in the neonatal rat. Endocrinology 138, 1736-1741.
    • (1997) Endocrinology , vol.138 , pp. 1736-1741
    • Scaglia, L.1    Cahill, C.J.2    Finegood, D.T.3    Bonner-Weir, S.4
  • 39
    • 58749115233 scopus 로고    scopus 로고
    • Cx36 makes channels coupling human pancreatic beta-cells, and correlates with insulin expression
    • Serre-Beinier V., Bosco D., Zulianello L. et al. (2009) Cx36 makes channels coupling human pancreatic beta-cells, and correlates with insulin expression. Hum. Mol. Genet. 18, 428-439.
    • (2009) Hum. Mol. Genet. , vol.18 , pp. 428-439
    • Serre-Beinier, V.1    Bosco, D.2    Zulianello, L.3
  • 40
    • 84873440296 scopus 로고    scopus 로고
    • Cholesterol reduction ameliorates glucose-induced calcium handling and insulin secretion in islets from low-density lipoprotein receptor knockout mice
    • Souza J.C., Vanzela E.C., Ribeiro R.A. et al. (2013) Cholesterol reduction ameliorates glucose-induced calcium handling and insulin secretion in islets from low-density lipoprotein receptor knockout mice. Biochim. Biophys. Acta 1831, 769-775.
    • (2013) Biochim. Biophys. Acta , vol.1831 , pp. 769-775
    • Souza, J.C.1    Vanzela, E.C.2    Ribeiro, R.A.3
  • 41
    • 80051826073 scopus 로고    scopus 로고
    • Dietary cholesterol exacerbates hepatic steatosis and inflammation in obese LDL receptor-deficient mice
    • Subramanian S., Goodspeed L., Wang S. et al. (2011) Dietary cholesterol exacerbates hepatic steatosis and inflammation in obese LDL receptor-deficient mice. J. Lipid Res. 52, 1626-1635.
    • (2011) J. Lipid Res. , vol.52 , pp. 1626-1635
    • Subramanian, S.1    Goodspeed, L.2    Wang, S.3
  • 42
    • 52049103091 scopus 로고    scopus 로고
    • Pancreas islets in metabolic signaling-focus on the beta-cell
    • Suckale J. & Solimena M. (2008) Pancreas islets in metabolic signaling-focus on the beta-cell. Front. Biosci. 13, 7156-7171.
    • (2008) Front. Biosci. , vol.13 , pp. 7156-7171
    • Suckale, J.1    Solimena, M.2
  • 43
    • 77956392948 scopus 로고    scopus 로고
    • Defects in insulin secretion and action in the pathogenesis of type 2 diabetes mellitus
    • Tripathy D. & Chavez A.O. (2010) Defects in insulin secretion and action in the pathogenesis of type 2 diabetes mellitus. Curr. Diab. Rep. 10, 184-191.
    • (2010) Curr. Diab. Rep. , vol.10 , pp. 184-191
    • Tripathy, D.1    Chavez, A.O.2
  • 44
    • 3543009434 scopus 로고    scopus 로고
    • The high-fat diet-fed mouse: a model for studying mechanisms and treatment of impaired glucose tolerance and type 2 diabetes
    • Winzell M.S. & Ahrén B. (2004) The high-fat diet-fed mouse: a model for studying mechanisms and treatment of impaired glucose tolerance and type 2 diabetes. Diabetes 53(Suppl 3), S215-S219.
    • (2004) Diabetes , vol.53 , Issue.Suppl 3
    • Winzell, M.S.1    Ahrén, B.2


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