Critical role of large-conductance calcium- and voltage-activated potassium channels in leptin-induced neuroprotection of N-methyl-d-aspartate-exposed cortical neurons

Pharmacological Research

Volumn 87, Issue , 2014, Pages 80-86

  Mancini, Maria ^a,b,c   Soldovieri, Maria Virginia ^a   Gessner, Guido ^c   Wissuwa, Bianka ^c   Barrese, Vincenzo ^d   Boscia, Francesca ^d   Secondo, Agnese ^d   Miceli, Francesco ^d   Franco, Cristina ^d   Ambrosino, Paolo ^a   Canzoniero, Lorella Maria Teresa ^b   Bauer, Michael ^c   Hoshi, Toshinori ^e   Heinemann, Stefan H ^c   Taglialatela, Maurizio ^a,d  

^a UNIVERSITY OF MOLISE   (Italy)

^b UNIVERSITY OF SANNIO   (Italy)

^c JENA UNIVERSITY HOSPITAL   (Germany)

^d UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^e UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Calcium and voltage activated potassium channels (BK channels); Cortical neurons; Iberiotoxin; Leptin; N methyl d aspartate (NMDA); Neuroprotection; Paxilline

Indexed keywords

ADIPOCYTOKINE; IBERIOTOXIN; LARGE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; LEPTIN; N METHYL DEXTRO ASPARTIC ACID; PAXILLINE; CALCIUM; N METHYLASPARTIC ACID; NEUROPROTECTIVE AGENT;

ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BRAIN CELL; BRAIN CELL CULTURE; CALCIUM CELL LEVEL; CELL DEATH; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG MECHANISM; IN VITRO STUDY; MOUSE; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; RAT; ANIMAL; ANIMAL EMBRYO; BRAIN CORTEX; CELL CULTURE; CYTOLOGY; DRUG EFFECTS; METABOLISM; NERVE CELL; TRANSGENIC MOUSE; WISTAR RAT;

ANIMALS; CALCIUM; CELLS, CULTURED; CEREBRAL CORTEX; EMBRYO, MAMMALIAN; LARGE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS; LEPTIN; MICE, TRANSGENIC; N-METHYLASPARTATE; NEURONS; NEUROPROTECTIVE AGENTS; RATS, WISTAR;

EID: 84903952923     PISSN: 10436618     EISSN: 10961186     Source Type: Journal    
DOI: 10.1016/j.phrs.2014.06.010     Document Type: Article

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