-
1
-
-
0029033861
-
The retinoblastoma protein and cell cycle control
-
Weinberg RA. The retinoblastoma protein and cell cycle control. Cell 1995; 81: 323-330.
-
(1995)
Cell
, vol.81
, pp. 323-330
-
-
Weinberg, R.A.1
-
2
-
-
0025905183
-
The E2F transcription factor is a cellular target for the RB protein
-
Chellappan SP, Hiebert S, Mudryj M, Horowitz JM, Nevins JR. The E2F transcription factor is a cellular target for the RB protein. Cell 1991; 65: 1053-1061.
-
(1991)
Cell
, vol.65
, pp. 1053-1061
-
-
Chellappan, S.P.1
Hiebert, S.2
Mudryj, M.3
Horowitz, J.M.4
Nevins, J.R.5
-
3
-
-
0037445901
-
E2F and cell cycle control: A double-edged sword
-
Stevens C, La Thangue NB. E2F and cell cycle control: a double-edged sword. Arch Biochem Biophys 2003; 412: 157-169.
-
(2003)
Arch Biochem Biophys
, vol.412
, pp. 157-169
-
-
Stevens, C.1
La Thangue, N.B.2
-
5
-
-
0025869428
-
Adenovirus-E1a prevents the retinoblastoma gene-product from complexing with a cellular transcription factor
-
Bandara LR, Lathangue NB. Adenovirus-E1a prevents the retinoblastoma gene-product from complexing with a cellular transcription factor. Nature 1991; 351: 494-497.
-
(1991)
Nature
, vol.351
, pp. 494-497
-
-
Bandara, L.R.1
Lathangue, N.B.2
-
6
-
-
0032146274
-
The regulation of E2F by pRB-family proteins
-
Dyson N. The regulation of E2F by pRB-family proteins. Genes Dev 1998; 12: 2245-2262.
-
(1998)
Genes Dev
, vol.12
, pp. 2245-2262
-
-
Dyson, N.1
-
7
-
-
2942722811
-
Molecular mechanisms of E2F-dependent activation and pRB-mediated repression
-
Frolov MV, Dyson NJ. Molecular mechanisms of E2F-dependent activation and pRB-mediated repression. J Cell Sci 2004; 117(Pt 11): 2173-2181.
-
(2004)
J Cell Sci
, vol.117
, Issue.PART 11
, pp. 2173-2181
-
-
Frolov, M.V.1
Dyson, N.J.2
-
8
-
-
0037383818
-
Dp1 is required for extra-embryonic development
-
Kohn MJ, Bronson RT, Harlow E, Dyson NJ, Yamasaki L. Dp1 is required for extra-embryonic development. Development 2003; 130: 1295-1305.
-
(2003)
Development
, vol.130
, pp. 1295-1305
-
-
Kohn, M.J.1
Bronson, R.T.2
Harlow, E.3
Dyson, N.J.4
Yamasaki, L.5
-
9
-
-
3543022688
-
Dp1 is largely dispensable for embryonic development
-
Kohn MJ, Leung SW, Criniti V, Agromayor M, Yamasaki L. Dp1 is largely dispensable for embryonic development. Mol Cell Biol 2004; 24: 7197-7205.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 7197-7205
-
-
Kohn, M.J.1
Leung, S.W.2
Criniti, V.3
Agromayor, M.4
Yamasaki, L.5
-
10
-
-
54049120956
-
E2F-at the crossroads of life and death
-
Polager S, Ginsberg D. E2F-at the crossroads of life and death. Trends Cell Biol 2008; 18: 528-535.
-
(2008)
Trends Cell Biol
, vol.18
, pp. 528-535
-
-
Polager, S.1
Ginsberg, D.2
-
11
-
-
0029949784
-
E2F-1 functions in mice to promote apoptosis and suppress proliferation
-
Field SJ, Tsai FY, Kuo F, Zubiaga AM, Kaelin Jr WG, Livingston DM et al. E2F-1 functions in mice to promote apoptosis and suppress proliferation. Cell 1996; 85: 549-561.
-
(1996)
Cell
, vol.85
, pp. 549-561
-
-
Field, S.J.1
Tsai, F.Y.2
Kuo, F.3
Zubiaga, A.M.4
Kaelin, Jr.W.G.5
Livingston, D.M.6
-
12
-
-
0032939925
-
Transcription factor E2F-1 is upregulated in response to DNA damage in a manner analogous to that of p53
-
Blattner C, Sparks A, Lane D. Transcription factor E2F-1 is upregulated in response to DNA damage in a manner analogous to that of p53. Mol Cell Biol 1999; 19: 3704-3713.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 3704-3713
-
-
Blattner, C.1
Sparks, A.2
Lane, D.3
-
14
-
-
84855394410
-
Transcriptional and nontranscriptional functions of E2F1 in response to DNA damage
-
Biswas AK, Johnson DG. Transcriptional and nontranscriptional functions of E2F1 in response to DNA damage. Cancer Res 2012; 72: 13-17.
-
(2012)
Cancer Res
, vol.72
, pp. 13-17
-
-
Biswas, A.K.1
Johnson, D.G.2
-
15
-
-
70349437076
-
P53 and E2f: Partners in life and death
-
Polager S, Ginsberg D. p53 and E2f: partners in life and death. Nat Rev Cancer 2009; 9: 738-748.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 738-748
-
-
Polager, S.1
Ginsberg, D.2
-
16
-
-
80053364368
-
First somatic mutation of E2F1 in a critical DNA binding residue discovered in well-differentiated papillary mesothelioma of the peritoneum
-
Yu W, Chan-On W, Teo M, Ong CK, Cutcutache I, Allen GE et al. First somatic mutation of E2F1 in a critical DNA binding residue discovered in well-differentiated papillary mesothelioma of the peritoneum. Genome Biol 2011; 12: R96.
-
(2011)
Genome Biol
, vol.12
-
-
Yu, W.1
Chan-On, W.2
Teo, M.3
Ong, C.K.4
Cutcutache, I.5
Allen, G.E.6
-
17
-
-
0034455671
-
Cell cycle control and cancer
-
Sherr CJ. Cell cycle control and cancer. Harvey Lect 2000; 96: 73-92.
-
(2000)
Harvey Lect
, vol.96
, pp. 73-92
-
-
Sherr, C.J.1
-
18
-
-
0030678627
-
Role of the retinoblastoma protein in the pathogenesis of human cancer
-
Sellers WR, Kaelin Jr WG. Role of the retinoblastoma protein in the pathogenesis of human cancer. J Clin Oncol 1997; 15: 3301-3312.
-
(1997)
J Clin Oncol
, vol.15
, pp. 3301-3312
-
-
Sellers, W.R.1
Kaelin, Jr.W.G.2
-
19
-
-
3843084078
-
The COSMIC (catalogue of somatic mutations in cancer) database and website
-
Bamford S, Dawson E, Forbes S, Clements J, Pettett R, Dogan A et al. The COSMIC (catalogue of somatic mutations in cancer) database and website. Br J Cancer 2004; 91: 355-358.
-
(2004)
Br J Cancer
, vol.91
, pp. 355-358
-
-
Bamford, S.1
Dawson, E.2
Forbes, S.3
Clements, J.4
Pettett, R.5
Dogan, A.6
-
20
-
-
84859169877
-
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity
-
Barretina J, Caponigro G, Stransky N, Venkatesan K, Margolin AA, Kim S et al. The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity. Nature 2012; 483: 603-607.
-
(2012)
Nature
, vol.483
, pp. 603-607
-
-
Barretina, J.1
Caponigro, G.2
Stransky, N.3
Venkatesan, K.4
Margolin, A.A.5
Kim, S.6
-
21
-
-
0033559030
-
Structural basis of DNA recognition by the heterodimeric cell cycle transcription factor E2F-DP
-
Zheng N, Fraenkel E, Pabo CO, Pavletich NP. Structural basis of DNA recognition by the heterodimeric cell cycle transcription factor E2F-DP. Genes Dev 1999; 13: 666-674.
-
(1999)
Genes Dev
, vol.13
, pp. 666-674
-
-
Zheng, N.1
Fraenkel, E.2
Pabo, C.O.3
Pavletich, N.P.4
-
22
-
-
0029912789
-
Nuclear accumulation of the E2F heterodimer regulated by subunit composition and alternative splicing of a nuclear localization signal
-
de la Luna S, Burden MJ, Lee CW, La Thangue NB. Nuclear accumulation of the E2F heterodimer regulated by subunit composition and alternative splicing of a nuclear localization signal. J Cell Sci 1996; 109(Pt 10): 2443-2452.
-
(1996)
J Cell Sci
, vol.109
, Issue.PART 10
, pp. 2443-2452
-
-
De La Luna, S.1
Burden, M.J.2
Lee, C.W.3
La Thangue, N.B.4
-
23
-
-
0029991715
-
Nuclear localization of DP and E2F transcription factors by heterodimeric partners and retinoblastoma protein family members
-
Magae J, Wu CL, Illenye S, Harlow E, Heintz NH. Nuclear localization of DP and E2F transcription factors by heterodimeric partners and retinoblastoma protein family members. J Cell Sci 1996; 109(Pt 7): 1717-1726.
-
(1996)
J Cell Sci
, vol.109
, Issue.PART 7
, pp. 1717-1726
-
-
Magae, J.1
Wu, C.L.2
Illenye, S.3
Harlow, E.4
Heintz, N.H.5
-
24
-
-
0027129389
-
Transcriptional regulation. A closer look at E2F
-
Nevins JR. Transcriptional regulation. A closer look at E2F. Nature 1992; 358: 375-376.
-
(1992)
Nature
, vol.358
, pp. 375-376
-
-
Nevins, J.R.1
-
25
-
-
0029049577
-
Cellular targets for activation by the E2F1 transcription factor include DNA synthesis-and G1/S-regulatory genes
-
DeGregori J, Kowalik T, Nevins JR. Cellular targets for activation by the E2F1 transcription factor include DNA synthesis-and G1/S-regulatory genes. Mol Cell Biol 1995; 15: 4215-4224.
-
(1995)
Mol Cell Biol
, vol.15
, pp. 4215-4224
-
-
Degregori, J.1
Kowalik, T.2
Nevins, J.R.3
-
26
-
-
28944437358
-
Structure of the Rb C-terminal domain bound to E2F1-DP1: A mechanism for phosphorylation-induced E2F release
-
Rubin SM, Gall AL, Zheng N, Pavletich NP. Structure of the Rb C-terminal domain bound to E2F1-DP1: a mechanism for phosphorylation-induced E2F release. Cell 2005; 123: 1093-1106.
-
(2005)
Cell
, vol.123
, pp. 1093-1106
-
-
Rubin, S.M.1
Gall, A.L.2
Zheng, N.3
Pavletich, N.P.4
-
27
-
-
0038142184
-
Differential regulation of E2F1 apoptotic target genes in response to DNA damage
-
Pediconi N, Ianari A, Costanzo A, Belloni L, Gallo R, Cimino L et al. Differential regulation of E2F1 apoptotic target genes in response to DNA damage. Nat Cell Biol 2003; 5: 552-558.
-
(2003)
Nat Cell Biol
, vol.5
, pp. 552-558
-
-
Pediconi, N.1
Ianari, A.2
Costanzo, A.3
Belloni, L.4
Gallo, R.5
Cimino, L.6
-
28
-
-
0035878122
-
Selective induction of E2F1 in response to DNA damage, mediated by ATM-dependent phosphorylation
-
Lin WC, Lin FT, Nevins JR. Selective induction of E2F1 in response to DNA damage, mediated by ATM-dependent phosphorylation. Genes Dev 2001; 15: 1833-1844.
-
(2001)
Genes Dev
, vol.15
, pp. 1833-1844
-
-
Lin, W.C.1
Lin, F.T.2
Nevins, J.R.3
-
29
-
-
0034720201
-
Exogenous E2F expression is growth inhibitory before, during, and after cellular transformation
-
Lee TA, Farnham PJ. Exogenous E2F expression is growth inhibitory before, during, and after cellular transformation. Oncogene 2000; 19: 2257-2268.
-
(2000)
Oncogene
, vol.19
, pp. 2257-2268
-
-
Lee, T.A.1
Farnham, P.J.2
-
30
-
-
0035063183
-
The Rb/E2F pathway and cancer
-
Nevins JR. The Rb/E2F pathway and cancer. Hum Mol Genet 2001; 10: 699-703.
-
(2001)
Hum Mol Genet
, vol.10
, pp. 699-703
-
-
Nevins, J.R.1
-
31
-
-
0034306996
-
The Rb/E2F pathway: Expanding roles and emerging paradigms
-
Harbour JW, Dean DC. The Rb/E2F pathway: expanding roles and emerging paradigms. Genes Dev 2000; 14: 2393-2409.
-
(2000)
Genes Dev
, vol.14
, pp. 2393-2409
-
-
Harbour, J.W.1
Dean, D.C.2
-
32
-
-
0037659644
-
Role of the RB tumor suppressor in cancer
-
Yamasaki L. Role of the RB tumor suppressor in cancer. Cancer Treat Res 2003; 115: 209-239.
-
(2003)
Cancer Treat Res
, vol.115
, pp. 209-239
-
-
Yamasaki, L.1
-
33
-
-
0030738479
-
Distinct roles for E2F proteins in cell growth control and apoptosis
-
DeGregori J, Leone G, Miron A, Jakoi L, Nevins JR. Distinct roles for E2F proteins in cell growth control and apoptosis. Proc Natl Acad Sci USA 1997; 94: 7245-7250.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 7245-7250
-
-
Degregori, J.1
Leone, G.2
Miron, A.3
Jakoi, L.4
Nevins, J.R.5
-
34
-
-
33750920705
-
Distinct and overlapping roles for E2F family members in transcription, proliferation and apoptosis
-
DeGregori J, Johnson DG. Distinct and overlapping roles for E2F family members in transcription, proliferation and apoptosis. Curr Mol Med 2006; 6: 739-748.
-
(2006)
Curr Mol Med
, vol.6
, pp. 739-748
-
-
Degregori, J.1
Johnson, D.G.2
-
35
-
-
0027434084
-
Functional synergy between DP-1 and E2F-1 in the cell cycle-regulating transcription factor DRTF1/E2F
-
Bandara LR, Buck VM, Zamanian M, Johnston LH, La Thangue NB. Functional synergy between DP-1 and E2F-1 in the cell cycle-regulating transcription factor DRTF1/E2F. EMBO J 1993; 12: 4317-4324.
-
(1993)
EMBO J
, vol.12
, pp. 4317-4324
-
-
Bandara, L.R.1
Buck, V.M.2
Zamanian, M.3
Johnston, L.H.4
La Thangue, N.B.5
-
36
-
-
0028334543
-
DP-1: A cell cycle-regulated and phosphorylated component of transcription factor DRTF1/E2F which is functionally important for recognition by pRb and the ade-novirus E4 orf 6/7 protein
-
Bandara LR, Lam EW, Sorensen TS, Zamanian M, Girling R, La Thangue NB. DP-1: a cell cycle-regulated and phosphorylated component of transcription factor DRTF1/E2F which is functionally important for recognition by pRb and the ade-novirus E4 orf 6/7 protein. EMBO J 1994; 13: 3104-3114.
-
(1994)
EMBO J
, vol.13
, pp. 3104-3114
-
-
Bandara, L.R.1
Lam, E.W.2
Sorensen, T.S.3
Zamanian, M.4
Girling, R.5
La Thangue, N.B.6
-
37
-
-
33745060148
-
A functionally distinct member of the DP family of E2F subunits
-
Milton A, Luoto K, Ingram L, Munro S, Logan N, Graham AL et al. A functionally distinct member of the DP family of E2F subunits. Oncogene 2006; 25: 3212-3218.
-
(2006)
Oncogene
, vol.25
, pp. 3212-3218
-
-
Milton, A.1
Luoto, K.2
Ingram, L.3
Munro, S.4
Logan, N.5
Graham, A.L.6
-
38
-
-
0031796924
-
Cell cycle-regulated expression of mammalian CDC6 is dependent on E2F
-
Hateboer G, Wobst A, Petersen BO, Le Cam L, Vigo E, Sardet C et al. Cell cycle-regulated expression of mammalian CDC6 is dependent on E2F. Mol Cell Biol 1998; 18: 6679-6697.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 6679-6697
-
-
Hateboer, G.1
Wobst, A.2
Petersen, B.O.3
Le Cam, L.4
Vigo, E.5
Sardet, C.6
-
39
-
-
0034977277
-
Apaf-1 is a transcriptional target for E2F and p53
-
Moroni MC, Hickman ES, Lazzerini Denchi E, Caprara G, Colli E, Cecconi F et al. Apaf-1 is a transcriptional target for E2F and p53. Nat Cell Biol 2001; 3: 552-558.
-
(2001)
Nat Cell Biol
, vol.3
, pp. 552-558
-
-
Moroni, M.C.1
Hickman, E.S.2
Lazzerini Denchi, E.3
Caprara, G.4
Colli, E.5
Cecconi, F.6
-
40
-
-
0029942908
-
Cell cycle regulation of the murine cyclin e gene depends on an E2F binding site in the promoter
-
Botz J, Zerfass-Thome K, Spitkovsky D, Delius H, Vogt B, Eilers M et al. Cell cycle regulation of the murine cyclin E gene depends on an E2F binding site in the promoter. Mol Cell Biol 1996; 16: 3401-3409.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 3401-3409
-
-
Botz, J.1
Zerfass-Thome, K.2
Spitkovsky, D.3
Delius, H.4
Vogt, B.5
Eilers, M.6
-
41
-
-
33645830066
-
DNA-damage-responsive acetylation of pRb regulates binding to E2F-1
-
Markham D, Munro S, Soloway J, O'Connor DP, La Thangue NB. DNA-damage-responsive acetylation of pRb regulates binding to E2F-1. EMBO Rep 2006; 7: 192-198.
-
(2006)
EMBO Rep
, vol.7
, pp. 192-198
-
-
Markham, D.1
Munro, S.2
Soloway, J.3
O'Connor, D.P.4
La Thangue, N.B.5
-
42
-
-
77951623834
-
Lysine methylation regulates the pRb tumour suppressor protein
-
Munro S, Khaire N, Inche A, Carr S, La Thangue NB. Lysine methylation regulates the pRb tumour suppressor protein. Oncogene 2010; 29: 2357-2367.
-
(2010)
Oncogene
, vol.29
, pp. 2357-2367
-
-
Munro, S.1
Khaire, N.2
Inche, A.3
Carr, S.4
La Thangue, N.B.5
|