Anti-VEGF therapy reduces intestinal inflammation in Endoglin heterozygous mice subjected to experimental colitis

Angiogenesis

Volumn 17, Issue 3, 2014, Pages 641-659

  Ardelean, Daniela S ^a,b   Yin, Melissa ^c   Jerkic, Mirjana ^a,b   Peter, Madonna ^a,b   Ngan, Bo ^a,d   Kerbel, Robert S ^c,d   Foster, F Stuart ^c,d   Letarte, Michelle ^a,b,d  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c SUNNYBROOK RESEARCH INSTITUTE   (Canada)

^d UNIVERSITY OF TORONTO   (Canada)

Author keywords

Angiogenesis; Anti VEGF therapy; Endoglin; Inflammation; VEGF

Indexed keywords

AMPHIREGULIN; CD31 ANTIGEN; DEXTRAN SULFATE; ENDOGLIN; GRANULOCYTE COLONY STIMULATING FACTOR; INTERLEUKIN 1BETA; MONOCLONAL ANTIBODY G6 31; MUCOSAL ADDRESSIN CELL ADHESION MOLECULE 1; SMAD1 PROTEIN; SMAD2 PROTEIN; SMAD5 PROTEIN; SMAD8 PROTEIN; UNCLASSIFIED DRUG; VASCULOTROPIN ANTIBODY; AUTACOID; ENDOGLIN PROTEIN, MOUSE; MONOCLONAL ANTIBODY; SIGNAL PEPTIDE; SMAD PROTEIN; TRANSFORMING GROWTH FACTOR BETA; VASCULOTROPIN A;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CAPILLARY DENSITY; COLONIC WALL THICKNESS; CONTRAST ENHANCEMENT; CONTROLLED STUDY; DIGESTIVE TRACT PARAMETERS; ECHOGRAPHY; EXPERIMENTAL COLITIS; FEMALE; HETEROZYGOSITY; HISTOLOGY; IN VITRO STUDY; IN VIVO STUDY; INTESTINAL MICROVASCULAR HEMODYNAMICS; MALE; MICROVASCULATURE; MOUSE; NONHUMAN; PRIORITY JOURNAL; TISSUE LEVEL; UPREGULATION; WILD TYPE; WOUND HEALING; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; COLITIS; COLON; DEFICIENCY; DRUG EFFECTS; HEMODYNAMICS; HETEROZYGOTE; INFLAMMATION; INTESTINE; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY;

MUS;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD31; COLITIS; COLON; FEMALE; GRANULOCYTE COLONY-STIMULATING FACTOR; HEMODYNAMICS; HETEROZYGOTE; INFLAMMATION; INFLAMMATION MEDIATORS; INTERLEUKIN-1BETA; INTESTINES; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MICE, INBRED C57BL; MICROVESSELS; SMAD PROTEINS; TRANSFORMING GROWTH FACTOR BETA; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84903888349     PISSN: 09696970     EISSN: 15737209     Source Type: Journal    
DOI: 10.1007/s10456-014-9421-x     Document Type: Article

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