Increased mucosal production of granulocyte colony-stimulating factor is related to a delay in neutrophil apoptosis in Inflammatory Bowel disease

Journal of Gastroenterology and Hepatology (Australia)

Volumn 14, Issue 1, 1999, Pages 46-53

  Ina, Kenji ^a   Kusugami, Kazuo ^a   Hosokawa, Takehiko ^a   Imada, Akira ^a   Shimizu, Tatsuji ^a   Yamaguchi, Takeo ^a   Ohsuga, Masahiro ^a   Kyokane, Kazuhiro ^a   Sakai, Tetsu ^a   Nishio, Yuji ^a   Yokoyama, Yasuhisa ^b   Ando, Takafumi ^a  

^a NAGOYA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b Yokoyama Gastrointestinal Hospital   (Japan)

Author keywords

Apoptosis; Granulocyte colony stimulating factor; Inflammatory Bowel disease; Polymorphonuclear neutrophil

Indexed keywords

ACRIDINE ORANGE; DNA FRAGMENT; ETHIDIUM BROMIDE; GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HISTONE; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR; RECOMBINANT GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; RECOMBINANT INTERLEUKIN 1BETA; RECOMBINANT INTERLEUKIN 6; RECOMBINANT INTERLEUKIN 8; RECOMBINANT TUMOR NECROSIS FACTOR ALPHA;

ADOLESCENT; ADULT; APOPTOSIS; ARTICLE; CLINICAL ARTICLE; COLON MUCOSA; CONTROLLED STUDY; CROHN DISEASE; ENTERITIS; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; NEUTROPHIL; ORGAN CULTURE; PRIORITY JOURNAL; ULCERATIVE COLITIS;

EID: 0033019574     PISSN: 08159319     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1440-1746.1999.01807.x     Document Type: Article

References (23)

1. Morson BC, Dawson IMP. Gastrointestinal Pathology. Oxford: Blackwell Science, 1979.
2. Weiss SJ. Tissue destruction by neutrophils. N. Engl. J. Med. 1989; 320: 365-76.
3. Davies GR, Banatvala N, Collins CE et al. Relationship between infective load of Helicobacter pylori and reactive oxygen metabolite production in antral mucosa. Scand. J. Gastroenterol. 1994; 29: 419-24.
4. Parkos CA, Colgan SP, Delp C, Arnaut MA, Madara JL. Neutrophil migration across a cultured epithelial monolayer elicits a biphasic resistance response representing sequential effects on transcellular and paracellular pathways. J. Cell. Biol. 1992; 117: 757-64.
5. Kurose I, Granger DN, Evans DJ et al. Helicobacter pylori-induced microvascular protein leakage in rats: Role of neutrophils, mast cells and platelets. Gastroenterology 1994; 107: 70-9.
6. Savill JS, Wyllie AH, Henson JE, Walport MJ, Henson PM, Haslett C. Macrophage phagocytosis of aging neutrophils in inflammation. J. Clin. Invest. 1989; 83: 865-75.
7. Brach MA, deVos S, Gruss HJ, Herrmann F. Prolongation of survival of human polymorphonuclear neutrophils by granulocyte-macrophage colony-stimulating factor is caused by inhibition of programmed cell death. Blood 1992; 80: 2920-1.
8. Colotta F, Re F, Polentarutti N, Sozzani S, Mantovani A. Modulation of granulocyte survival and programmed cell death by cytokines and bacterial products. Blood 1992; 80: 2012-20.
9. Lee A, Whyte MKB, Haslett C. Inhibition of apoptosis and prolongation of neutrophil functional longevity by inflammatory mediators. J. Leuk. Biol. 1993; 54: 283-8.
10. Hall SE, Savill JS, Henson PM, Haslett C. Apoptotic neutrophils are phagocytosed by fibroblasts with participation of the fibroblast vitronectin receptor and involvement of a mannose/fucose-specific lectin. J. Immunol. 1994; 153: 3218-27.
11. Pullman WE, Elsbury S, Kobayashi M, Hapel AJ, Doe WF. Enhanced mucosal cytokine production in inflammatory bowel disease. Gastroenterology 1992; 102: 529-37.
12. Kusugami K, Fukatsu A, Tanimoto M et al. Elevation of interleukin-6 in inflammatory bowel disease is macrophage- and epithelial cell-dependent. Dig. Dis. Sci. 1995; 40: 949-59.
13. Peterson GL. A simplification of the protein assay method of Lowry et al. which is more generally applicable. Anal. Biochem. 1977; 83: 346-56.
14. Kusugami K, Ando T, Ohsuga M et al. Mucosal chemokine activity in Helicobacter pylori infection. J. Clin. Gastroenterol. 1997; 25: S203-10.
15. Zhou P, Qian L, Kozopas KM, Craig RW. Mcl-1, a Bcl-2 family member, delays the death of hematopoietic cells under a variety of apoptosis-inducing conditions. Blood 1997; 89: 630-43.
16. Gavrieli Y, Sherman Y, Ben-Sasson SA. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J. Cell. Biol. 1992; 119: 493-501.
17. Kasama T, Strieter RM, Lukacs NW, Lincoln PM, Burdick MD, Kunkel SL. Interferon gamma modulates the expression of neutrophil-derived chemokines. J. Invest. Med. 1995; 43: 58-67.
18. MacDonald TT, Hutchings P, Choy MY, Murch SH, Cooke A. Tumor necrosis factor-alpha and interferon-gamma production measured at a single cell level in normal and inflamed human intestine. Clin. Exp. Immunol. 1990; 81: 301-5.
19. Ligumsky M, Simon PL, Karmeli F, Rachmilewitz D. Role of interleukin 1 in inflammatory bowel disease: Enhanced production during active disease. Gut 1990; 31: 686-9.
20. Mahida YR, Ceska M, Effenberger F, Kurlak L, Lindley I, Hawkey CJ. Enhanced synthesis of neutrophil-activating peptide-1/interleukin-8 in active ulcerative colitis. Clin. Sci. 1992; 82: 273-5.
21. Ina K, Kusugami K, Yamaguchi T et al. Mucosal interleukin-8 is involved in neutrophil migration and binding to extracellular matrix in inflammatory bowel disease. Am. J. Gastroenterol. 1997; 92: 1342-6.
22. Sakai T, Kusugami K, Nishimura H et al. Interleukin-15 activity in the rectal mucosa of inflammatory bowel disease. Gastroenterology 1998; 114: 1237-43.
23. Jenkins D, Balsitis M, Gallivan S et al. Guidelines for the initial biopsy diagnosis of suspected chronic idiopathic inflammatory bowel disease. The British Society of Gastroenterology initiative. J. Clin. Pathol. 1997; 50: 93-105.