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Volumn 14, Issue 8, 2014, Pages

Imaging the role of amyloid in PD dementia and dementia with Lewy bodies

Author keywords

Amyloid; Dementia with Lewy bodies; Parkinson disease dementia; PET; Pittsburgh compound B

Indexed keywords

(3 IODOBENZYL)GUANIDINE; 2 [1 [6 [(2 FLUOROETHYL)(METHYL)AMINO] 2 NAPHTHYL]ETHYLIDENE]MALONONITRILE F 18; AMYLOID; AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-42]; CARBON 11; FLORBETABEN; FLORBETAPIR F 18; FLUORINE 18; FLUTAMETAMOL F 18; N SEC BUTYL 1 (2 CHLOROPHENYL) N METHYL 3 ISOQUINOLINECARBOXAMIDE C 11; PBR 28 C 11; PITTSBURGH COMPOUND B; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG;

EID: 84903873943     PISSN: 15284042     EISSN: 15346293     Source Type: Journal    
DOI: 10.1007/s11910-014-0472-6     Document Type: Article
Times cited : (35)

References (118)
  • 6
    • 84858336551 scopus 로고    scopus 로고
    • Antemortem amyloid imaging and β-amyloid pathology in a case with dementia with Lewy bodies
    • Kantarci K, Yang C, Schneider JA, Senjem ML, Reyes DA, Lowe VJ, et al. Antemortem amyloid imaging and β-amyloid pathology in a case with dementia with Lewy bodies. Neurobiol Aging. 2012;33:878-85.
    • (2012) Neurobiol Aging , vol.33 , pp. 878-885
    • Kantarci, K.1    Yang, C.2    Schneider, J.A.3    Senjem, M.L.4    Reyes, D.A.5    Lowe, V.J.6
  • 12
    • 77649314191 scopus 로고    scopus 로고
    • APOE predicts amyloid-beta but not tau Alzheimer pathology in cognitively normal aging
    • Morris JC, Roe CM, Xiong C, Fagan AM, Goate AM, Holtzman DM, et al. APOE predicts amyloid-beta but not tau Alzheimer pathology in cognitively normal aging. Ann Neurol. 2010;67: 122-31.
    • (2010) Ann Neurol , vol.67 , pp. 122-131
    • Morris, J.C.1    Roe, C.M.2    Xiong, C.3    Fagan, A.M.4    Goate, A.M.5    Holtzman, D.M.6
  • 15
    • 38149081191 scopus 로고    scopus 로고
    • Imaging of amyloid β in Alzheimer's disease with 18F-BAY94-9172, a novel PET tracer: Proof of mechanism
    • Rowe CC, Ackerman U, Browne W, Mulligan R, Pike KL, O'Keefe G, et al. Imaging of amyloid β in Alzheimer's disease with 18F-BAY94-9172, a novel PET tracer: proof of mechanism. Lancet Neurol. 2008;7:129-35.
    • (2008) Lancet Neurol , vol.7 , pp. 129-135
    • Rowe, C.C.1    Ackerman, U.2    Browne, W.3    Mulligan, R.4    Pike, K.L.5    O'Keefe, G.6
  • 16
    • 77953937194 scopus 로고    scopus 로고
    • In vivo imaging of amyloid deposition in Alzheimer disease using the radioligand 18F-AV-45 (florbetapir [corrected] F 18)
    • Wong DF, Rosenberg PB, Zhou Y, Kumar A, Raymont V, Ravert HT, et al. In vivo imaging of amyloid deposition in Alzheimer disease using the radioligand 18F-AV-45 (florbetapir [corrected] F 18). J Nucl Med. 2010;51:913-20.
    • (2010) J Nucl Med , vol.51 , pp. 913-920
    • Wong, D.F.1    Rosenberg, P.B.2    Zhou, Y.3    Kumar, A.4    Raymont, V.5    Ravert, H.T.6
  • 20
    • 79957694788 scopus 로고    scopus 로고
    • Florbetapir F-18: A histopathologically validated beta-amyloid positron emission tomography imaging agent
    • Lister-James J, Pontecorvo MJ, Clark C, Joshi AD, Mintun MA, Zhang W, et al. Florbetapir F-18: a histopathologically validated beta-amyloid positron emission tomography imaging agent. Semin Nucl Med. 2011;41:300-4.
    • (2011) Semin Nucl Med , vol.41 , pp. 300-304
    • Lister-James, J.1    Pontecorvo, M.J.2    Clark, C.3    Joshi, A.D.4    Mintun, M.A.5    Zhang, W.6
  • 21
    • 84863869296 scopus 로고    scopus 로고
    • Cerebral PETwith florbetapir compared with neuropathology at autopsy for detection of neuritic amyloid-β plaques: A prospective cohort study
    • Clark CM, Pontecorvo MJ, Beach TG, Bedell BJ, Coleman RE, Doraiswamy PM, et al. Cerebral PETwith florbetapir compared with neuropathology at autopsy for detection of neuritic amyloid-β plaques: a prospective cohort study. Lancet Neurol. 2012;11:669-78.
    • (2012) Lancet Neurol , vol.11 , pp. 669-678
    • Clark, C.M.1    Pontecorvo, M.J.2    Beach, T.G.3    Bedell, B.J.4    Coleman, R.E.5    Doraiswamy, P.M.6
  • 22
    • 84876876010 scopus 로고    scopus 로고
    • 18F]flutemetamol using positron emission tomography compared with parietal biopsy samples in living normal pressure hydrocephalus patients
    • 18F]flutemetamol using positron emission tomography compared with parietal biopsy samples in living normal pressure hydrocephalus patients. Mol Imaging Biol. 2013;15:230-7.
    • (2013) Mol Imaging Biol , vol.15 , pp. 230-237
    • Wong, D.F.1    Moghekar, A.R.2    Rigamonti, D.3    Brašić, J.R.4    Rousset, O.5    Willis, W.6
  • 23
    • 80051688987 scopus 로고    scopus 로고
    • 18F-florbetaben in Alzheimer disease and other dementias
    • Florbetaben was used to assess and compare amyloid burden in AD subjects, DLB subjects, PD subjects, FTD subjects, vascular dementia subjects, and HCS, and demonstrated results similar to those obtained with PiB
    • 18F-florbetaben in Alzheimer disease and other dementias. J Nucl Med. 2011;52:1210-7. Florbetaben was used to assess and compare amyloid burden in AD subjects, DLB subjects, PD subjects, FTD subjects, vascular dementia subjects, and HCS, and demonstrated results similar to those obtained with PiB.
    • (2011) J Nucl Med , vol.52 , pp. 1210-1217
    • Villemagne, V.L.1    Ong, K.2    Mulligan, R.S.3    Holl, G.4    Pejoska, S.5    Jones, G.6
  • 24
    • 84903743480 scopus 로고    scopus 로고
    • Amyloid PET imaging in Alzheimer's disease: A comparison of three radiotracers
    • Alzheimer 's Disease Neuroimaging Initiative. doi:10. 1007/s00259-014-2753-3. This article showed high correlation in PET characteristics among PiB, florbetapir, and flutemetamol
    • • Landau SM, Thomas BA, Thurfjell L, Schmidt M, Margolin R, Mintun M, et al. Alzheimer 's Disease Neuroimaging Initiative. Amyloid PET imaging in Alzheimer's disease: a comparison of three radiotracers. Eur J Nucl Med Mol Imaging. 2014. doi:10. 1007/s00259-014-2753-3. This article showed high correlation in PET characteristics among PiB, florbetapir, and flutemetamol.
    • (2014) Eur J Nucl Med Mol Imaging
    • Landau, S.M.1    Thomas, B.A.2    Thurfjell, L.3    Schmidt, M.4    Margolin, R.5    Mintun, M.6
  • 26
    • 33745028473 scopus 로고    scopus 로고
    • The 2,6-disubstituted naphthalene derivative FDDNP labeling reliably predicts Congo red birefringence of protein deposits in brain sections of selected human neurodegenerative diseases
    • DOI 10.1111/j.1750-3639.2006.00006.x
    • Smid LM, Vovko TD, Popovic M, Petric A, Kepe V, Barrio JR, et al. The 2,6-disubstituted naphthalene derivative FDDNP labeling reliably predicts Congo red birefringence of protein deposits in brain sections of selected human neurodegenerative diseases. Brain Pathol. 2006;16:124-30. (Pubitemid 43876472)
    • (2006) Brain Pathology , vol.16 , Issue.2 , pp. 124-130
    • Smid, L.M.1    Vovko, T.D.2    Popovic, M.3    Petric, A.4    Kepe, V.5    Barrio, J.R.6    Vidmar, G.7    Bresjanac, M.8
  • 29
    • 77954033257 scopus 로고    scopus 로고
    • Amyloid imaging results from the Australian Imaging, Biomarkers and Lifestyle (AIBL) study of aging
    • Rowe CC, Ellis KA, Rimajova M, Bourgeat P, Pike KE, Jones G, et al. Amyloid imaging results from the Australian Imaging, Biomarkers and Lifestyle (AIBL) study of aging. Neurobiol Aging. 2010;31:1275-83.
    • (2010) Neurobiol Aging , vol.31 , pp. 1275-1283
    • Rowe, C.C.1    Ellis, K.A.2    Rimajova, M.3    Bourgeat, P.4    Pike, K.E.5    Jones, G.6
  • 30
    • 84857776667 scopus 로고    scopus 로고
    • APOE modifies the association between Aβ load and cognition in cognitively normal older adults
    • Kantarci K, Lowe V, Przybelski SA, Weigand SD, Senjem ML, Ivnik RJ, et al. APOE modifies the association between Aβ load and cognition in cognitively normal older adults. Neurology. 2012;78:232-40.
    • (2012) Neurology , vol.78 , pp. 232-240
    • Kantarci, K.1    Lowe, V.2    Przybelski, S.A.3    Weigand, S.D.4    Senjem, M.L.5    Ivnik, R.J.6
  • 33
    • 84876385490 scopus 로고    scopus 로고
    • Meta-analysis of amyloid-cognition relations in cognitively normal older adults
    • Hedden T, Oh H, Younger AP, Patel TA. Meta-analysis of amyloid-cognition relations in cognitively normal older adults. Neurology. 2013;80:1341-8.
    • (2013) Neurology , vol.80 , pp. 1341-1348
    • Hedden, T.1    Oh, H.2    Younger, A.P.3    Patel, T.A.4
  • 34
  • 35
    • 84905557091 scopus 로고    scopus 로고
    • Florbetapir F 18 amyloid PET and 36-month cognitive decline: A prospective multicenter study
    • AV45-A11 Study Group. doi:10.1038/mp.2014.9
    • Doraiswamy PM, Sperling RA, Johnson K, Reiman EM, Wong TZ, Sabbagh MN, et al. AV45-A11 Study Group. Florbetapir F 18 amyloid PET and 36-month cognitive decline: a prospective multicenter study. Mol Psychiatry. 2014. doi:10.1038/mp.2014.9.
    • (2014) Mol Psychiatry
    • Doraiswamy, P.M.1    Sperling, R.A.2    Johnson, K.3    Reiman, E.M.4    Wong, T.Z.5    Sabbagh, M.N.6
  • 39
    • 0020077835 scopus 로고
    • Relationship of motor symptoms to intellectual deficits in Parkinson disease
    • Mortimer JA, Pirozzolo FJ, Hansch EC, Webster DD. Relationship of motor symptoms to intellectual deficits in Parkinson disease. Neurology. 1982;32:133-7. (Pubitemid 12223994)
    • (1982) Neurology , vol.32 , Issue.2 , pp. 133-137
    • Mortimer, J.A.1    Pirozzolo, F.J.2    Hansch, E.C.3    Webster, D.D.4
  • 40
    • 80052267232 scopus 로고    scopus 로고
    • MDS task force on mild cognitive impairment in Parkinson's disease: Critical review of PD-MCI
    • Litvan I, Aarsland D, Adler CH, Goldman JG, Kulisevsky J, Mollenhauer B, et al. MDS task force on mild cognitive impairment in Parkinson's disease: critical review of PD-MCI. Mov Disord. 2011;26:1814-24.
    • (2011) Mov Disord , vol.26 , pp. 1814-1824
    • Litvan, I.1    Aarsland, D.2    Adler, C.H.3    Goldman, J.G.4    Kulisevsky, J.5    Mollenhauer, B.6
  • 41
    • 0026751822 scopus 로고
    • A population-based investigation of Parkinson's disease with and without dementia. Relationship to age and gender
    • Mayeux R, Denaro J, Hemenegildo N, Marder K, Tang MX, Cote LJ, et al. A population-based investigation of Parkinson's disease with and without dementia. Relationship to age and gender Arch Neurol. 1992;49:492-7.
    • (1992) Arch Neurol , vol.49 , pp. 492-497
    • Mayeux, R.1    Denaro, J.2    Hemenegildo, N.3    Marder, K.4    Tang, M.X.5    Cote, L.J.6
  • 42
    • 0037335814 scopus 로고    scopus 로고
    • Prevalence and characteristics of dementia in Parkinson disease: An 8-year prospective study
    • DOI 10.1001/archneur.60.3.387
    • Aarsland D, Andersen K, Larsen JP, Lolk A, Kragh-Sorensen P. Prevalence and characteristics of dementia in Parkinson disease: an 8-year prospective study. Arch Neurol. 2003;60:387-92. (Pubitemid 36314364)
    • (2003) Archives of Neurology , vol.60 , Issue.3 , pp. 387-392
    • Aarsland, D.1    Andersen, K.2    Larsen, J.P.3    Lolk, A.4    Kragh-Sorensen, P.5
  • 46
    • 0024395281 scopus 로고
    • Dementia in Parkinson's disease is related to neuronal loss in the medial substantia nigra
    • Rinne JO, Rummukainen J, Paljarvi L, Rinne UK. Dementia in Parkinson's disease is related to neuronal loss in the medial substantia nigra. Ann Neurol. 1989;26:47-50. (Pubitemid 19190042)
    • (1989) Annals of Neurology , vol.26 , Issue.1 , pp. 47-50
    • Rinne, J.O.1    Rummukainen, J.2    Paljarvi, L.3    Rinne, U.K.4
  • 48
    • 84879601960 scopus 로고    scopus 로고
    • The many faces of alpha-synuclein mutations
    • Kasten M, Klein C. The many faces of alpha-synuclein mutations. Mov Disord. 2013;28:697-701.
    • (2013) Mov Disord , vol.28 , pp. 697-701
    • Kasten, M.1    Klein, C.2
  • 50
    • 0034827449 scopus 로고    scopus 로고
    • Cortical Lewy body pathology in the diagnosis of dementia
    • Harding AJ, Halliday GM. Cortical Lewy body pathology in the diagnosis of dementia. Acta Neuropathol. 2001;102:355-63. (Pubitemid 32894706)
    • (2001) Acta Neuropathologica , vol.102 , Issue.4 , pp. 355-363
    • Harding, A.J.1    Halliday, G.M.2
  • 52
    • 73549085595 scopus 로고    scopus 로고
    • Increased expression of alpha-synuclein reduces neurotransmitter release by inhibiting synaptic vesicle reclustering after endocytosis
    • Nemani VM, Lu W, Berge V, Nakamura K, Onoa B, Lee MK, et al. Increased expression of alpha-synuclein reduces neurotransmitter release by inhibiting synaptic vesicle reclustering after endocytosis. Neuron. 2010;65:66-79.
    • (2010) Neuron , vol.65 , pp. 66-79
    • Nemani, V.M.1    Lu, W.2    Berge, V.3    Nakamura, K.4    Onoa, B.5    Lee, M.K.6
  • 53
    • 77957264418 scopus 로고    scopus 로고
    • The synaptic pathology of alpha-synuclein aggregation in dementia with Lewy bodies, Parkinson's disease and Parkinson's disease dementia
    • Schulz-Schaeffer WJ. The synaptic pathology of alpha-synuclein aggregation in dementia with Lewy bodies, Parkinson's disease and Parkinson's disease dementia. Acta Neuropathol. 2010;120:131-43.
    • (2010) Acta Neuropathol , vol.120 , pp. 131-143
    • Schulz-Schaeffer, W.J.1
  • 54
    • 84898830649 scopus 로고    scopus 로고
    • The neurobiological basis of cognitive impairment in Parkinson's disease
    • Halliday GM, Leverenz JB, Schneider JS, Adler CH. The neurobiological basis of cognitive impairment in Parkinson's disease. Mov Disord. 2014;29:634-50.
    • (2014) Mov Disord , vol.29 , pp. 634-650
    • Halliday, G.M.1    Leverenz, J.B.2    Schneider, J.S.3    Adler, C.H.4
  • 55
    • 41149152169 scopus 로고    scopus 로고
    • Prevalence and impact of vascular and Alzheimer pathologies in Lewy body disease
    • Jellinger KA, Attems J. Prevalence and impact of vascular and Alzheimer pathologies in Lewy body disease. Acta Neuropathol. 2008;115:427-36.
    • (2008) Acta Neuropathol , vol.115 , pp. 427-436
    • Jellinger, K.A.1    Attems, J.2
  • 56
  • 58
    • 0036202684 scopus 로고    scopus 로고
    • Impact of coexistent Alzheimer pathology on the natural history of Parkinson's disease
    • DOI 10.1007/s007020200027
    • Jellinger KA, Seppi K, Wenning GK, Poewe W. Impact of coexistent Alzheimer pathology on the natural history of Parkinson's disease. J Neural Transm. 2002;109:329-39. (Pubitemid 34251637)
    • (2002) Journal of Neural Transmission , vol.109 , Issue.3 , pp. 329-339
    • Jellinger, K.A.1    Seppi, K.2    Wenning, G.K.3    Poewe, W.4
  • 59
    • 0031779243 scopus 로고    scopus 로고
    • Cortical Lewy bodies and Alzheimer-type changes in patients with Parkinson's disease
    • Mattila PM, Röyttä M, Torikka H, Dickson DW, Rinne JO. Cortical Lewy bodies and Alzheimer-type changes in patients with Parkinson's disease. Acta Neuropathol. 1998;95:576-82.
    • (1998) Acta Neuropathol , vol.95 , pp. 576-582
    • Mattila, P.M.1    Röyttä, M.2    Torikka, H.3    Dickson, D.W.4    Rinne, J.O.5
  • 60
    • 79957453213 scopus 로고    scopus 로고
    • Lewy- and Alzheimer-type pathologies in Parkinson's disease dementia: Which is more important?
    • Compta Y, Parkkinen L, O'Sullivan SS, Vandrovcova J, Holton JL, Collins C, et al. Lewy- and Alzheimer-type pathologies in Parkinson's disease dementia: which is more important? Brain. 2011;134:1493-505.
    • (2011) Brain , vol.134 , pp. 1493-1505
    • Compta, Y.1    Parkkinen, L.2    O'Sullivan, S.S.3    Vandrovcova, J.4    Holton, J.L.5    Collins, C.6
  • 61
    • 0025276828 scopus 로고
    • Cognitive impairment in Parkinson's disease: Amyloid plagues, neurofibrillary tangles, and neuropil threads in the cerebral cortex
    • DOI 10.1007/BF02251245
    • Braak H, Braak E. Cognitive impairment in Parkinson's disease: amyloid plaques, neurofibrillary tangles, and neuropil threads in the cerebral cortex. J Neural Transm Park Dis Dement Sect. 1990;2:45-57. (Pubitemid 20215381)
    • (1990) Journal of Neural Transmission - Parkinson's Disease and Dementia Section , vol.2 , Issue.1 , pp. 45-57
    • Braak, H.1    Braak, E.2
  • 64
    • 33845709899 scopus 로고    scopus 로고
    • Differences in neuropathologic characteristics across the Lewy body dementia spectrum
    • DOI 10.1212/01.wnl.0000249130.63615.cc, PII 0000611420061212000009
    • Ballard C, Ziabreva I, Perry R, Larsen JP, O'Brien J, McKeith I, et al. Differences in neuropathologic characteristics across the Lewy body dementia spectrum. Neurology. 2006;67:1931-4. (Pubitemid 44967366)
    • (2006) Neurology , vol.67 , Issue.11 , pp. 1931-1934
    • Ballard, C.1    Ziabreva, I.2    Perry, R.3    Larsen, J.P.4    O'Brien, J.5    McKeith, I.6    Perry, E.7    Aarsland, D.8
  • 65
    • 77957924992 scopus 로고    scopus 로고
    • Distribution of cerebral amyloid deposition and its relevance to clinical phenotype in Lewy body dementia
    • Fujishiro H, Iseki E, Higashi S, Kasanuki K, Murayama N, Togo T, et al. Distribution of cerebral amyloid deposition and its relevance to clinical phenotype in Lewy body dementia. Neurosci Lett. 2010;486:19-23.
    • (2010) Neurosci Lett , vol.486 , pp. 19-23
    • Fujishiro, H.1    Iseki, E.2    Higashi, S.3    Kasanuki, K.4    Murayama, N.5    Togo, T.6
  • 68
    • 78650626088 scopus 로고    scopus 로고
    • Striatal Aβ peptide deposition mirrors dementia and differentiates DLB and PDD from other parkinsonian syndromes
    • Kalaitzakis ME, Walls AJ, Pearce RK, Gentleman SM. Striatal Aβ peptide deposition mirrors dementia and differentiates DLB and PDD from other parkinsonian syndromes. Neurobiol Dis. 2011;41:377-84.
    • (2011) Neurobiol Dis , vol.41 , pp. 377-384
    • Kalaitzakis, M.E.1    Walls, A.J.2    Pearce, R.K.3    Gentleman, S.M.4
  • 70
    • 35048814562 scopus 로고    scopus 로고
    • Predictors of survival in dementia with Lewy bodies and Parkinson dementia
    • DOI 10.1159/000107703
    • Jellinger KA, Wenning GK, Seppi K. Predictors of survival in dementia with Lewy bodies and Parkinson dementia. Neurodegener Dis. 2007;4:428-30. (Pubitemid 47557284)
    • (2007) Neurodegenerative Diseases , vol.4 , Issue.6 , pp. 428-430
    • Jellinger, K.A.1    Wenning, G.K.2    Seppi, K.3
  • 73
    • 62149140954 scopus 로고    scopus 로고
    • Cortical PIB binding in Lewy body disease is associated with Alzheimer-like characteristics
    • Maetzler W, Liepelt I, Reimold M, Reischl G, Solbach C, Becker C, et al. Cortical PIB binding in Lewy body disease is associated with Alzheimer-like characteristics. Neurobiol Dis. 2009;34:107-12.
    • (2009) Neurobiol Dis , vol.34 , pp. 107-112
    • Maetzler, W.1    Liepelt, I.2    Reimold, M.3    Reischl, G.4    Solbach, C.5    Becker, C.6
  • 76
    • 84864005418 scopus 로고    scopus 로고
    • Brain amyloid and cognition in Lewy body diseases
    • This article confirmed prior results showing greater PiB retention in DLB compared with PDD and PD and showed that age and apolipoprotein ε4 contribute to PiB burden in Lewy body diseases, as they do in HCS and AD subjects
    • • Gomperts SN, Locascio JJ, Marquie M, Santarlasci AL, Rentz DM, Maye J, et al. Brain amyloid and cognition in Lewy body diseases. Mov Disord. 2012;27:965-73. This article confirmed prior results showing greater PiB retention in DLB compared with PDD and PD and showed that age and apolipoprotein ε4 contribute to PiB burden in Lewy body diseases, as they do in HCS and AD subjects.
    • (2012) Mov Disord , vol.27 , pp. 965-973
    • Gomperts, S.N.1    Locascio, J.J.2    Marquie, M.3    Santarlasci, A.L.4    Rentz, D.M.5    Maye, J.6
  • 77
    • 84878564712 scopus 로고    scopus 로고
    • Microglia, amyloid, and glucose metabolism in Parkinson's disease with and without dementia
    • Edison P, Ahmed I, Fan Z, Hinz R, Gelosa G, Ray Chaudhuri K, et al. Microglia, amyloid, and glucose metabolism in Parkinson's disease with and without dementia. Neuropsychopharmacology. 2013;38:938-49.
    • (2013) Neuropsychopharmacology , vol.38 , pp. 938-949
    • Edison, P.1    Ahmed, I.2    Fan, Z.3    Hinz, R.4    Gelosa, G.5    Ray Chaudhuri, K.6
  • 78
    • 84901228427 scopus 로고    scopus 로고
    • PET imaging of amyloid with Florbetapir F 18 and PET imaging of dopamine degeneration with 18F-AV-133 (florbenazine) in patients with Alzheimer's disease and Lewy body disorders
    • Florbetapir and the vesicular monoamine transporter ligand florbenazine were used to differentiate between AD subjects, DLB subjects, PD subjects, and HCS
    • • Siderowf A, Pontecorvo MJ, Shill HA, Mintun MA, Arora A, Joshi AD, et al. PET imaging of amyloid with Florbetapir F 18 and PET imaging of dopamine degeneration with 18F-AV-133 (florbenazine) in patients with Alzheimer's disease and Lewy body disorders. BMC Neurol. 2014;14:79. Florbetapir and the vesicular monoamine transporter ligand florbenazine were used to differentiate between AD subjects, DLB subjects, PD subjects, and HCS.
    • (2014) BMC Neurol , vol.14 , pp. 79
    • Siderowf, A.1    Pontecorvo, M.J.2    Shill, H.A.3    Mintun, M.A.4    Arora, A.5    Joshi, A.D.6
  • 79
    • 84878872401 scopus 로고    scopus 로고
    • PET imaging of neuropathology in tauopathies: Progressive supranuclear palsy
    • Kepe V, Bordelon Y, Boxer A, Huang SC, Liu J, Thiede FC, et al. PET imaging of neuropathology in tauopathies: progressive supranuclear palsy. J Alzheimers Dis. 2013;36:145-53.
    • (2013) J Alzheimers Dis , vol.36 , pp. 145-153
    • Kepe, V.1    Bordelon, Y.2    Boxer, A.3    Huang, S.C.4    Liu, J.5    Thiede, F.C.6
  • 80
    • 84867510729 scopus 로고    scopus 로고
    • Aβ-amyloid deposition in patients with Parkinson disease at risk for development of dementia
    • Petrou M, Bohnen NI, Müller ML, Koeppe RA, Albin RL, Frey KA. Aβ-amyloid deposition in patients with Parkinson disease at risk for development of dementia. Neurology. 2012;79:1161-7.
    • (2012) Neurology , vol.79 , pp. 1161-1167
    • Petrou, M.1    Bohnen, N.I.2    Müller, M.L.3    Koeppe, R.A.4    Albin, R.L.5    Frey, K.A.6
  • 81
    • 84873647470 scopus 로고    scopus 로고
    • Amyloid is linked to cognitive decline in patients with Parkinson disease without dementia
    • This article shows that baseline amyloid burden predicts cognitive decline in PD
    • • Gomperts SN, Locascio JJ, Rentz D, Santarlasci A, Marquie M, Johnson KA, et al. Amyloid is linked to cognitive decline in patients with Parkinson disease without dementia. Neurology. 2013;80:85-91. This article shows that baseline amyloid burden predicts cognitive decline in PD.
    • (2013) Neurology , vol.80 , pp. 85-91
    • Gomperts, S.N.1    Locascio, J.J.2    Rentz, D.3    Santarlasci, A.4    Marquie, M.5    Johnson, K.A.6
  • 83
    • 84874221857 scopus 로고    scopus 로고
    • β-Amyloid in Lewy body disease is related to Alzheimer's disease-like atrophy
    • This article associated amyloid burden in DLB and PDD with medial temporal lobe and cortical atrophy
    • • Shimada H, Shinotoh H, Hirano S, Miyoshi M, Sato K, Tanaka N, et al. β-Amyloid in Lewy body disease is related to Alzheimer's disease-like atrophy. Mov Disord. 2013;28:169-75. This article associated amyloid burden in DLB and PDD with medial temporal lobe and cortical atrophy.
    • (2013) Mov Disord , vol.28 , pp. 169-175
    • Shimada, H.1    Shinotoh, H.2    Hirano, S.3    Miyoshi, M.4    Sato, K.5    Tanaka, N.6
  • 86
    • 79957798322 scopus 로고    scopus 로고
    • Assessment of mild dementia with amyloid and dopamine terminal positron emission tomography
    • PiB and vesicular monoamine transporter imaging of the dopamine terminal were used to differentiate AD, DLB, and FTD subjects with mild dementia
    • • Burke JF, Albin RL, Koeppe RA, Giordani B, Kilbourn MR, Gilman S, et al. Assessment of mild dementia with amyloid and dopamine terminal positron emission tomography. Brain. 2011;134:1647-57. PiB and vesicular monoamine transporter imaging of the dopamine terminal were used to differentiate AD, DLB, and FTD subjects with mild dementia.
    • (2011) Brain , vol.134 , pp. 1647-1657
    • Burke, J.F.1    Albin, R.L.2    Koeppe, R.A.3    Giordani, B.4    Kilbourn, M.R.5    Gilman, S.6
  • 87
    • 84863448289 scopus 로고    scopus 로고
    • Multimodality imaging characteristics of dementia with Lewy bodies
    • This article compared AD and DLB patients using MRI, PiB imaging, and fluorodeoxyglucose imaging; a subset of patients underwent neuropathological evaluation. It found that a single imaging modality did not differentiate groups or individual patients well, but that using at least two modalities improved their discrimination
    • • Kantarci K, Lowe VJ, Boeve BF, Weigand SD, Senjem ML, Przybelski SA, et al. Multimodality imaging characteristics of dementia with Lewy bodies. Neurobiol Aging. 2012;33:2091-105. This article compared AD and DLB patients using MRI, PiB imaging, and fluorodeoxyglucose imaging; a subset of patients underwent neuropathological evaluation. It found that a single imaging modality did not differentiate groups or individual patients well, but that using at least two modalities improved their discrimination.
    • (2012) Neurobiol Aging , vol.33 , pp. 2091-2105
    • Kantarci, K.1    Lowe, V.J.2    Boeve, B.F.3    Weigand, S.D.4    Senjem, M.L.5    Przybelski, S.A.6
  • 90
    • 84857843988 scopus 로고    scopus 로고
    • Early AD pathology in a [C-11]PiB-negative case: A PiB-amyloid imaging, biochemical, and immunohistochemical study
    • This article explored the sensitivity of PiB and PiB imaging in a case of DLB with negative PiB imaging findings, and found that in some brain regions Aβ levels were significant, exceeding local plaque density and PiB binding
    • • Ikonomovic MD, Abrahamson EE, Price JC, Hamilton RL, Mathis CA, Paljug WR, et al. Early AD pathology in a [C-11]PiB-negative case: a PiB-amyloid imaging, biochemical, and immunohistochemical study. Acta Neuropathol. 2012;123:433-47. This article explored the sensitivity of PiB and PiB imaging in a case of DLB with negative PiB imaging findings, and found that in some brain regions Aβ levels were significant, exceeding local plaque density and PiB binding.
    • (2012) Acta Neuropathol , vol.123 , pp. 433-447
    • Ikonomovic, M.D.1    Abrahamson, E.E.2    Price, J.C.3    Hamilton, R.L.4    Mathis, C.A.5    Paljug, W.R.6
  • 91
  • 92
    • 33748357972 scopus 로고    scopus 로고
    • Changes in motor subtype and risk for incident dementia in Parkinson's disease
    • DOI 10.1002/mds.20897
    • Alves G, Larsen JP, Emre M, Wentzel-Larsen T, Aarsland D. Changes in motor subtype and risk for incident dementia in Parkinson's disease. Mov Disord. 2006;21:1123-30. (Pubitemid 44336596)
    • (2006) Movement Disorders , vol.21 , Issue.8 , pp. 1123-1130
    • Alves, G.1    Larsen, J.P.2    Emre, M.3    Wentzel-Larsen, T.4    Aarsland, D.5
  • 93
    • 84875483820 scopus 로고    scopus 로고
    • β-Amyloid and postural instability and gait difficulty in Parkinson's disease at risk for dementia
    • This article reported a relationship between amyloid burden and postural instability in PD with MCI
    • • Müller ML, Frey KA, Petrou M, Kotagal V, Koeppe RA, Albin RL, et al. β-Amyloid and postural instability and gait difficulty in Parkinson's disease at risk for dementia. Mov Disord. 2013;28:296-301. This article reported a relationship between amyloid burden and postural instability in PD with MCI.
    • (2013) Mov Disord , vol.28 , pp. 296-301
    • Müller, M.L.1    Frey, K.A.2    Petrou, M.3    Kotagal, V.4    Koeppe, R.A.5    Albin, R.L.6
  • 95
    • 77949423619 scopus 로고    scopus 로고
    • Cerebrospinal fluid and plasma biomarkers in Alzheimer disease
    • Blennow K, Hampel H, Weiner M, Zetterberg H. Cerebrospinal fluid and plasma biomarkers in Alzheimer disease. Nat Rev Neurol. 2010;6:131-44.
    • (2010) Nat Rev Neurol , vol.6 , pp. 131-144
    • Blennow, K.1    Hampel, H.2    Weiner, M.3    Zetterberg, H.4
  • 96
    • 84892918273 scopus 로고    scopus 로고
    • Alzheimer's Disease Neuroimaging Initiative. Comparing positron emission tomography imaging and cerebrospinal fluid measurements of β-amyloid
    • This study found that florbetapir PET findings and CSF levels of Aβ were highly correlated across HCS, MCI subjects, and AD subjects
    • • Landau SM, Lu M, Joshi AD, Pontecorvo M, Mintun MA, Trojanowski JQ, et al. Alzheimer's Disease Neuroimaging Initiative. Comparing positron emission tomography imaging and cerebrospinal fluid measurements of β-amyloid. Ann Neurol. 2013;74:826-36. This study found that florbetapir PET findings and CSF levels of Aβ were highly correlated across HCS, MCI subjects, and AD subjects.
    • (2013) Ann Neurol , vol.74 , pp. 826-836
    • Landau, S.M.1    Lu, M.2    Joshi, A.D.3    Pontecorvo, M.4    Mintun, M.A.5    Trojanowski, J.Q.6
  • 97
    • 84868585835 scopus 로고    scopus 로고
    • Accuracy of a panel of 5 cerebrospinal fluid biomarkers in the differential diagnosis of patients with dementia and/or parkinsonian disorders
    • Hall S, Öhrfelt A, Constantinescu R, Andreasson U, Surova Y, Bostrom F, et al. Accuracy of a panel of 5 cerebrospinal fluid biomarkers in the differential diagnosis of patients with dementia and/or parkinsonian disorders. Arch Neurol. 2012;69:1445-52.
    • (2012) Arch Neurol , vol.69 , pp. 1445-1452
    • Hall, S.1    Öhrfelt, A.2    Constantinescu, R.3    Andreasson, U.4    Surova, Y.5    Bostrom, F.6
  • 98
  • 100
    • 77957220702 scopus 로고    scopus 로고
    • CSF amyloid β 1-42 predicts cognitive decline in Parkinson disease
    • This article shows that the baseline CSF level of Aβ predicts cognitive decline in PD
    • • Siderowf A, Xie SX, Hurtig H, Weintraub D, Duda J, Chen-Plotkin A, et al. CSF amyloid β 1-42 predicts cognitive decline in Parkinson disease. Neurology. 2010;75:1055-61. This article shows that the baseline CSF level of Aβ predicts cognitive decline in PD.
    • (2010) Neurology , vol.75 , pp. 1055-1061
    • Siderowf, A.1    Xie, S.X.2    Hurtig, H.3    Weintraub, D.4    Duda, J.5    Chen-Plotkin, A.6
  • 101
    • 84902173245 scopus 로고    scopus 로고
    • CSF Aβ42 predicts early-onset dementia in Parkinson disease
    • This article replicates the result in [100] showing that the baseline CSF level of Aβ predicts cognitive decline in PD
    • • Alves G, Lange J, Blennow K, Zetterberg H, Andreasson U, Førland MG, et al. CSF Aβ42 predicts early-onset dementia in Parkinson disease. Neurology. 2014;82:1784-90. This article replicates the result in [100] showing that the baseline CSF level of Aβ predicts cognitive decline in PD.
    • (2014) Neurology , vol.82 , pp. 1784-1790
    • Alves, G.1    Lange, J.2    Blennow, K.3    Zetterberg, H.4    Andreasson, U.5    Førland, M.G.6
  • 102
    • 0034624908 scopus 로고    scopus 로고
    • Decreased CSF amyloid β42 and normal tau levels in dementia with Lewy bodies
    • Kanemaru K, Kameda N, Yamanouchi H. Decreased CSF amyloid β42 and normal tau levels in dementia with Lewy bodies. Neurology. 2000;54:1875-6. (Pubitemid 30428428)
    • (2000) Neurology , vol.54 , Issue.9 , pp. 1875-1876
    • Kanemaru, K.1    Kameda, N.2    Yamanouchi, H.3
  • 103
    • 34848885454 scopus 로고    scopus 로고
    • PIB is a non-specific imaging marker of amyloid-beta (Aβ) peptide-related cerebral amyloidosis
    • DOI 10.1093/brain/awm191
    • Lockhart A, Lamb JR, Osredkar T, Sue LI, Joyce JN, Ye L, et al. PIB is a non-specific imaging marker of amyloid-beta (Aβ) peptide-related cerebral amyloidosis. Brain. 2007;130:2607-15. (Pubitemid 47511709)
    • (2007) Brain , vol.130 , Issue.10 , pp. 2607-2615
    • Lockhart, A.1    Lamb, J.R.2    Osredkar, T.3    Sue, L.I.4    Joyce, J.N.5    Ye, L.6    Libri, V.7    Leppert, D.8    Beach, T.G.9
  • 106
    • 84896479748 scopus 로고    scopus 로고
    • The prevalence and incidence of dementia with Lewy bodies: A systematic review of population and clinical studies
    • Vann Jones SA, O'Brien JT. The prevalence and incidence of dementia with Lewy bodies: a systematic review of population and clinical studies. Psychol Med. 2014;44:673-83.
    • (2014) Psychol Med , vol.44 , pp. 673-683
    • Vann Jones, S.A.1    O'Brien, J.T.2
  • 107
    • 0035834076 scopus 로고    scopus 로고
    • β-Amyloid peptides enhance α-synuclein accumulation and neuronal deficits in a transgenic mouse model linking Alzheimer's disease and Parkinson's disease
    • Masliah E, Rockenstein E, Veinbergs I, Sagara Y, Mallory M, Hashimoto M, et al. β-Amyloid peptides enhance α-synuclein accumulation and neuronal deficits in a transgenic mouse model linking Alzheimer's disease and Parkinson's disease. Proc Natl Acad Sci U S A. 2001;98:12245-50.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 12245-12250
    • Masliah, E.1    Rockenstein, E.2    Veinbergs, I.3    Sagara, Y.4    Mallory, M.5    Hashimoto, M.6
  • 108
    • 84861378458 scopus 로고    scopus 로고
    • Interaction between pathogenic proteins in neurodegenerative disorders
    • This review discusses synergistic interactions between Aβ, tau, and α-synuclein that could contribute to neurodegeneration in PD and DLB
    • • Jellinger KA. Interaction between pathogenic proteins in neurodegenerative disorders. J Cell Mol Med. 2012;16:1166-83. This review discusses synergistic interactions between Aβ, tau, and α-synuclein that could contribute to neurodegeneration in PD and DLB.
    • (2012) J Cell Mol Med , vol.16 , pp. 1166-1183
    • Jellinger, K.A.1
  • 109
    • 84859885003 scopus 로고    scopus 로고
    • Biomarkers in dementia with Lewy bodies: A review
    • This review focuses on biomarkers in DLB
    • • Sinha N, Firbank M, O'Brien JT. Biomarkers in dementia with Lewy bodies: a review. Int J Geriatr Psychiatry. 2012;27:443-53. This review focuses on biomarkers in DLB.
    • (2012) Int J Geriatr Psychiatry , vol.27 , pp. 443-453
    • Sinha, N.1    Firbank, M.2    O'Brien, J.T.3
  • 110
    • 84898770196 scopus 로고    scopus 로고
    • What can biomarkers tell us about cognition in Parkinson's disease?
    • This review discusses biomarkers in PD
    • • Mollenhauer B, Rochester L, Chen-Plotkin A, Brooks D. What can biomarkers tell us about cognition in Parkinson's disease?Mov Disord. 2014;29:622-33. This review discusses biomarkers in PD.
    • (2014) Mov Disord , vol.29 , pp. 622-633
    • Mollenhauer, B.1    Rochester, L.2    Chen-Plotkin, A.3    Brooks, D.4
  • 111
    • 84878624956 scopus 로고    scopus 로고
    • Assessing mild cognitive impairment with amyloid and dopamine terminal molecular imaging
    • Albin RL, Burke JF, Koeppe RA, Giordani B, Gilman S, Frey KA. Assessing mild cognitive impairment with amyloid and dopamine terminal molecular imaging. J Nucl Med. 2013;54:887-93.
    • (2013) J Nucl Med , vol.54 , pp. 887-893
    • Albin, R.L.1    Burke, J.F.2    Koeppe, R.A.3    Giordani, B.4    Gilman, S.5    Frey, K.A.6
  • 112
    • 84877906835 scopus 로고    scopus 로고
    • Tau pathology and neurodegeneration
    • Spillantini MG, Goedert M. Tau pathology and neurodegeneration. Lancet Neurol. 2013;12:609-22.
    • (2013) Lancet Neurol , vol.12 , pp. 609-622
    • Spillantini, M.G.1    Goedert, M.2
  • 113
    • 77049090834 scopus 로고    scopus 로고
    • Selective interaction of lansoprazole and astemizole with tau polymers: Potential new clinical use in diagnosis of Alzheimer's disease
    • Rojo LE, Alzate-Morales J, Saavedra IN, Davies P, Maccioni RB. Selective interaction of lansoprazole and astemizole with tau polymers: potential new clinical use in diagnosis of Alzheimer's disease. J Alzheimers Dis. 2010;19:573-89.
    • (2010) J Alzheimers Dis , vol.19 , pp. 573-589
    • Rojo, L.E.1    Alzate-Morales, J.2    Saavedra, I.N.3    Davies, P.4    Maccioni, R.B.5
  • 115
    • 84884273839 scopus 로고    scopus 로고
    • Imaging of tau pathology in a tauopathy mouse model and in Alzheimer patients compared to normal controls
    • Maruyama M, Shimada H, Suhara T, Shinotoh H, Ji B, Maeda J, et al. Imaging of tau pathology in a tauopathy mouse model and in Alzheimer patients compared to normal controls. Neuron. 2013;79:1094-108.
    • (2013) Neuron , vol.79 , pp. 1094-1108
    • Maruyama, M.1    Shimada, H.2    Suhara, T.3    Shinotoh, H.4    Ji, B.5    Maeda, J.6
  • 117
    • 84887230291 scopus 로고    scopus 로고
    • Early clinical PET imaging results with the novel PHF-tau radioligand [F18]-T808
    • Chien DT, Szardenings AK, Bahri S, Walsh JC, Mu F, Xia C, et al. Early clinical PET imaging results with the novel PHF-tau radioligand [F18]-T808. J Alzheimers Dis. 2014;38:171-84.
    • (2014) J Alzheimers Dis , vol.38 , pp. 171-184
    • Chien, D.T.1    Szardenings, A.K.2    Bahri, S.3    Walsh, J.C.4    Mu, F.5    Xia, C.6
  • 118
    • 84901391350 scopus 로고    scopus 로고
    • Non-invasive assessment of Alzheimer's disease neurofibrillary pathology using 18F-THK5105 PET
    • doi:10.1093/brain/awu064
    • Okamura N, Furumoto S, Fodero-Tavoletti MT, Mulligan RS, Harada R, Yates P, et al. Non-invasive assessment of Alzheimer's disease neurofibrillary pathology using 18F-THK5105 PET. Brain. 2014. doi:10.1093/brain/awu064.
    • (2014) Brain
    • Okamura, N.1    Furumoto, S.2    Fodero-Tavoletti, M.T.3    Mulligan, R.S.4    Harada, R.5    Yates, P.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.